1GYGA

R32 closed form of alpha-toxin from clostridium perfringens strain cer89l43
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
370
structure length
370
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords PHOSPHOLIPASE C
total genus 131
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2002-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1gygA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1gygA02
3SNGA 1F8NA 4JDGA 1FGOA 1QMDA 1GPLA 3O8YA 2FFZA 3BNEA 1AK0A 5EEOA 5FBFA 3CWZB 3FG3A 1ETHA 3FG4A 1KHOA 2P0MA 1FGTA 3V98A 3V99A 1LPBB 2HUCA 2OXEA 4CXVA 1NO3A 1N8QA 2IUKA 3PZWA 1LPAB 1FGMA 3V92A 1AH7A 2FGNA 3VF1A 1JNQA 1W52X 1FGRA 4WHAA 2WXTA 5FB9A 1LNHA 1RRHA 1FGQA 1BU8A 4QWTA 1CA1A 2SBLA 4DJ4A 2IUJA 3W52A 4CXOA 1HPLA 4WFOA 5FBAA 1P5XA 3BNCA 1P6DA 5FBDA 5FBBA 5FBGA 4CXPA 3BNBA 1OLPA 5FBCA 1P6EA 4NREA 1HU9A 1Y4KA 1LOXA 4CWMA 2WXUA 1GYGA 1YGEA 1RP1A 1ROVA 2PVSA 1IK3A 1N8SA 3FG1A 2WY6A 3BNDA 2PPLA 1RRLA 2FNQA 1QM6A
chains in the Genus database with same CATH superfamily
3SNGA 1F8NA 4JDGA 1FGOA 1QMDA 1GPLA 3O8YA 2FFZA 3BNEA 1AK0A 5EEOA 5FBFA 3CWZB 3FG3A 1ETHA 3FG4A 1KHOA 2P0MA 3U6GA 1FGTA 3V98A 3V99A 2QZ7A 1LPBB 2HUCA 2OXEA 4CXVA 1NO3A 1N8QA 2IUKA 2XHHA 3PZWA 1LPAB 1FGMA 3V92A 1AH7A 2FGNA 3VF1A 1JNQA 1W52X 1FGRA 4WHAA 2WXTA 5FB9A 2XHJA 1LNHA 1RRHA 4QEYA 1FGQA 1BU8A 4QWTA 1CA1A 2SBLA 4DJ4A 2IUJA 3W52A 4CXOA 1HPLA 4WFOA 5FBAA 1P5XA 3BNCA 1P6DA 2LG7A 5FBDA 5FBBA 5FBGA 4CXPA 2XFDA 3BNBA 1OLPA 5FBCA 2KXTA 1P6EA 4NREA 1HU9A 2LRGA 1Y4KA 1LOXA 4CWMA 2XFEA 2WXUA 1GYGA 2KXVA 2LGEA 1YGEA 1RP1A 1ROVA 2PVSA 1IK3A 1N8SA 3FG1A 2QNGA 2WY6A 3BNDA 3IBZA 2PPLA 1RRLA 2FNQA 1QM6A
chains in the Genus database with same CATH topology
3SNGA 1F8NA 4JDGA 1FGOA 1QMDA 1GPLA 3O8YA 2FFZA 3BNEA 1AK0A 5EEOA 5FBFA 3CWZB 3FG3A 1ETHA 3FG4A 1KHOA 2P0MA 1FGTA 3V98A 3V99A 1LPBB 2HUCA 2OXEA 4CXVA 1NO3A 1N8QA 2IUKA 3PZWA 1LPAB 1FGMA 3V92A 1AH7A 2FGNA 3VF1A 1JNQA 1W52X 1FGRA 4WHAA 2WXTA 5FB9A 1LNHA 1RRHA 1FGQA 1BU8A 4QWTA 1CA1A 2SBLA 4DJ4A 2IUJA 3W52A 4CXOA 1HPLA 4WFOA 5FBAA 1P5XA 3BNCA 1P6DA 5FBDA 5FBBA 5FBGA 4CXPA 3BNBA 1OLPA 5FBCA 1P6EA 4NREA 1HU9A 1Y4KA 1LOXA 4CWMA 2WXUA 1GYGA 1YGEA 1RP1A 1ROVA 2PVSA 1IK3A 1N8SA 3FG1A 2WY6A 3BNDA 2PPLA 1RRLA 2FNQA 1QM6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SNG A;  1F8N A;  4JDG A;  1FGO A;  1QMD A;  1GPL A;  3O8Y A;  2FFZ A;  3BNE A;  1AK0 A;  5EEO A;  5FBF A;  3CWZ B;  3FG3 A;  1ETH A;  3FG4 A;  1KHO A;  2P0M A;  1FGT A;  3V98 A;  3V99 A;  1LPB B;  2HUC A;  2OXE A;  4CXV A;  1NO3 A;  1N8Q A;  2IUK A;  3PZW A;  1LPA B;  1FGM A;  3V92 A;  1AH7 A;  2FGN A;  3VF1 A;  1JNQ A;  1W52 X;  1FGR A;  4WHA A;  2WXT A;  5FB9 A;  1LNH A;  1RRH A;  1FGQ A;  1BU8 A;  4QWT A;  1CA1 A;  2SBL A;  4DJ4 A;  2IUJ A;  3W52 A;  4CXO A;  1HPL A;  4WFO A;  5FBA A;  1P5X A;  3BNC A;  1P6D A;  5FBD A;  5FBB A;  5FBG A;  4CXP A;  3BNB A;  1OLP A;  5FBC A;  1P6E A;  4NRE A;  1HU9 A;  1Y4K A;  1LOX A;  4CWM A;  2WXU A;  1GYG A;  1YGE A;  1RP1 A;  1ROV A;  2PVS A;  1IK3 A;  1N8S A;  3FG1 A;  2WY6 A;  3BND A;  2PPL A;  1RRL A;  2FNQ A;  1QM6 A; 
#chains in the Genus database with same CATH topology
 3SNG A;  1F8N A;  4JDG A;  1FGO A;  1QMD A;  1GPL A;  3O8Y A;  2FFZ A;  3BNE A;  1AK0 A;  5EEO A;  5FBF A;  3CWZ B;  3FG3 A;  1ETH A;  3FG4 A;  1KHO A;  2P0M A;  3U6G A;  1FGT A;  3V98 A;  3V99 A;  2QZ7 A;  1LPB B;  2HUC A;  2OXE A;  4CXV A;  1NO3 A;  1N8Q A;  2IUK A;  2XHH A;  3PZW A;  1LPA B;  1FGM A;  3V92 A;  1AH7 A;  2FGN A;  3VF1 A;  1JNQ A;  1W52 X;  1FGR A;  4WHA A;  2WXT A;  5FB9 A;  2XHJ A;  1LNH A;  1RRH A;  4QEY A;  1FGQ A;  1BU8 A;  4QWT A;  1CA1 A;  2SBL A;  4DJ4 A;  2IUJ A;  3W52 A;  4CXO A;  1HPL A;  4WFO A;  5FBA A;  1P5X A;  3BNC A;  1P6D A;  2LG7 A;  5FBD A;  5FBB A;  5FBG A;  4CXP A;  2XFD A;  3BNB A;  1OLP A;  5FBC A;  2KXT A;  1P6E A;  4NRE A;  1HU9 A;  2LRG A;  1Y4K A;  1LOX A;  4CWM A;  2XFE A;  2WXU A;  1GYG A;  2KXV A;  2LGE A;  1YGE A;  1RP1 A;  1ROV A;  2PVS A;  1IK3 A;  1N8S A;  3FG1 A;  2QNG A;  2WY6 A;  3BND A;  3IBZ A;  2PPL A;  1RRL A;  2FNQ A;  1QM6 A; 
#chains in the Genus database with same CATH homology
 3SNG A;  1F8N A;  4JDG A;  1FGO A;  1QMD A;  1GPL A;  3O8Y A;  2FFZ A;  3BNE A;  1AK0 A;  5EEO A;  5FBF A;  3CWZ B;  3FG3 A;  1ETH A;  3FG4 A;  1KHO A;  2P0M A;  1FGT A;  3V98 A;  3V99 A;  1LPB B;  2HUC A;  2OXE A;  4CXV A;  1NO3 A;  1N8Q A;  2IUK A;  3PZW A;  1LPA B;  1FGM A;  3V92 A;  1AH7 A;  2FGN A;  3VF1 A;  1JNQ A;  1W52 X;  1FGR A;  4WHA A;  2WXT A;  5FB9 A;  1LNH A;  1RRH A;  1FGQ A;  1BU8 A;  4QWT A;  1CA1 A;  2SBL A;  4DJ4 A;  2IUJ A;  3W52 A;  4CXO A;  1HPL A;  4WFO A;  5FBA A;  1P5X A;  3BNC A;  1P6D A;  5FBD A;  5FBB A;  5FBG A;  4CXP A;  3BNB A;  1OLP A;  5FBC A;  1P6E A;  4NRE A;  1HU9 A;  1Y4K A;  1LOX A;  4CWM A;  2WXU A;  1GYG A;  1YGE A;  1RP1 A;  1ROV A;  2PVS A;  1IK3 A;  1N8S A;  3FG1 A;  2WY6 A;  3BND A;  2PPL A;  1RRL A;  2FNQ A;  1QM6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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