1GYGA

R32 closed form of alpha-toxin from clostridium perfringens strain cer89l43
Total Genus 131
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
131
sequence length
370
structure length
370
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTVGCKTNEDFYADILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKVIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the C. Perfringens Alpha-Toxin with the Active Site Closed by a Flexible Loop Region
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords PHOSPHOLIPASE C
total genus 131
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2002-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1gygA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1gygA02
5FBCA 1LNHA 3FG3A 1QMDA 1QM6A 5FBGA 4WHAA 4WFOA 1P6DA 1IK3A 1RP1A 5FBAA 1FGTA 1YGEA 2P0MA 3V99A 5EEOA 2PVSA 1GYGA 3V98A 3V92A 2IUJA 4JDGA 1AK0A 2HUCA 2PPLA 1FGOA 1FGMA 2SBLA 1RRHA 1GPLA 1LPAB 3BNDA 3FG4A 5FB9A 1AH7A 1N8QA 1NO3A 4CWMA 1FGRA 1F8NA 1Y4KA 2WY6A 1OLPA 2FNQA 3BNCA 1BU8A 1P5XA 3O8YA 3FG1A 1ROVA 3PZWA 2WXUA 1CA1A 4DJ4A 1LOXA 2FGNA 1N8SA 1P6EA 3VF1A 3SNGA 5FBFA 3CWZB 5FBDA 1RRLA 4CXPA 1W52X 2FFZA 2OXEA 3BNEA 1LPBB 2WXTA 2IUKA 1FGQA 1KHOA 1HPLA 3W52A 4NREA 4CXVA 5FBBA 3BNBA 4CXOA 4QWTA 1JNQA 1HU9A 1ETHA
chains in the Genus database with same CATH superfamily
3IBZA 5FBCA 1LNHA 3FG3A 3U6GA 1QMDA 1QM6A 5FBGA 4WHAA 4WFOA 1P6DA 1IK3A 1RP1A 5FBAA 2QNGA 1FGTA 2XFEA 1YGEA 2P0MA 3V99A 5EEOA 2PVSA 1GYGA 3V98A 2XHJA 3V92A 2IUJA 4JDGA 1AK0A 2HUCA 2PPLA 1FGOA 1FGMA 2SBLA 1RRHA 1GPLA 1LPAB 3BNDA 3FG4A 5FB9A 1AH7A 1N8QA 1NO3A 4CWMA 1FGRA 2LRGA 1F8NA 1Y4KA 2WY6A 1OLPA 2FNQA 3BNCA 1BU8A 1P5XA 3O8YA 3FG1A 2XFDA 1ROVA 3PZWA 2WXUA 1CA1A 4DJ4A 1LOXA 2FGNA 1N8SA 1P6EA 2KXTA 3VF1A 3SNGA 5FBFA 3CWZB 4QEYA 5FBDA 1RRLA 4CXPA 2LG7A 1W52X 2FFZA 2OXEA 3BNEA 1LPBB 2WXTA 2IUKA 1FGQA 1KHOA 1HPLA 3W52A 4NREA 1HU9A 2KXVA 4CXVA 5FBBA 3BNBA 4CXOA 4QWTA 2XHHA 1JNQA 2LGEA 2QZ7A 1ETHA
chains in the Genus database with same CATH topology
5FBCA 1LNHA 3FG3A 1QMDA 1QM6A 5FBGA 4WHAA 4WFOA 1P6DA 1IK3A 1RP1A 5FBAA 1FGTA 1YGEA 2P0MA 3V99A 5EEOA 2PVSA 1GYGA 3V98A 3V92A 2IUJA 4JDGA 1AK0A 2HUCA 2PPLA 1FGOA 1FGMA 2SBLA 1RRHA 1GPLA 1LPAB 3BNDA 3FG4A 5FB9A 1AH7A 1N8QA 1NO3A 4CWMA 1FGRA 1F8NA 1Y4KA 2WY6A 1OLPA 2FNQA 3BNCA 1BU8A 1P5XA 3O8YA 3FG1A 1ROVA 3PZWA 2WXUA 1CA1A 4DJ4A 1LOXA 2FGNA 1N8SA 1P6EA 3VF1A 3SNGA 5FBFA 3CWZB 5FBDA 1RRLA 4CXPA 1W52X 2FFZA 2OXEA 3BNEA 1LPBB 2WXTA 2IUKA 1FGQA 1KHOA 1HPLA 3W52A 4NREA 4CXVA 5FBBA 3BNBA 4CXOA 4QWTA 1JNQA 1HU9A 1ETHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FBC A;  1LNH A;  3FG3 A;  1QMD A;  1QM6 A;  5FBG A;  4WHA A;  4WFO A;  1P6D A;  1IK3 A;  1RP1 A;  5FBA A;  1FGT A;  1YGE A;  2P0M A;  3V99 A;  5EEO A;  2PVS A;  1GYG A;  3V98 A;  3V92 A;  2IUJ A;  4JDG A;  1AK0 A;  2HUC A;  2PPL A;  1FGO A;  1FGM A;  2SBL A;  1RRH A;  1GPL A;  1LPA B;  3BND A;  3FG4 A;  5FB9 A;  1AH7 A;  1N8Q A;  1NO3 A;  4CWM A;  1FGR A;  1F8N A;  1Y4K A;  2WY6 A;  1OLP A;  2FNQ A;  3BNC A;  1BU8 A;  1P5X A;  3O8Y A;  3FG1 A;  1ROV A;  3PZW A;  2WXU A;  1CA1 A;  4DJ4 A;  1LOX A;  2FGN A;  1N8S A;  1P6E A;  3VF1 A;  3SNG A;  5FBF A;  3CWZ B;  5FBD A;  1RRL A;  4CXP A;  1W52 X;  2FFZ A;  2OXE A;  3BNE A;  1LPB B;  2WXT A;  2IUK A;  1FGQ A;  1KHO A;  1HPL A;  3W52 A;  4NRE A;  4CXV A;  5FBB A;  3BNB A;  4CXO A;  4QWT A;  1JNQ A;  1HU9 A;  1ETH A; 
#chains in the Genus database with same CATH topology
 3IBZ A;  5FBC A;  1LNH A;  3FG3 A;  3U6G A;  1QMD A;  1QM6 A;  5FBG A;  4WHA A;  4WFO A;  1P6D A;  1IK3 A;  1RP1 A;  5FBA A;  2QNG A;  1FGT A;  2XFE A;  1YGE A;  2P0M A;  3V99 A;  5EEO A;  2PVS A;  1GYG A;  3V98 A;  2XHJ A;  3V92 A;  2IUJ A;  4JDG A;  1AK0 A;  2HUC A;  2PPL A;  1FGO A;  1FGM A;  2SBL A;  1RRH A;  1GPL A;  1LPA B;  3BND A;  3FG4 A;  5FB9 A;  1AH7 A;  1N8Q A;  1NO3 A;  4CWM A;  1FGR A;  2LRG A;  1F8N A;  1Y4K A;  2WY6 A;  1OLP A;  2FNQ A;  3BNC A;  1BU8 A;  1P5X A;  3O8Y A;  3FG1 A;  2XFD A;  1ROV A;  3PZW A;  2WXU A;  1CA1 A;  4DJ4 A;  1LOX A;  2FGN A;  1N8S A;  1P6E A;  2KXT A;  3VF1 A;  3SNG A;  5FBF A;  3CWZ B;  4QEY A;  5FBD A;  1RRL A;  4CXP A;  2LG7 A;  1W52 X;  2FFZ A;  2OXE A;  3BNE A;  1LPB B;  2WXT A;  2IUK A;  1FGQ A;  1KHO A;  1HPL A;  3W52 A;  4NRE A;  1HU9 A;  2KXV A;  4CXV A;  5FBB A;  3BNB A;  4CXO A;  4QWT A;  2XHH A;  1JNQ A;  2LGE A;  2QZ7 A;  1ETH A; 
#chains in the Genus database with same CATH homology
 5FBC A;  1LNH A;  3FG3 A;  1QMD A;  1QM6 A;  5FBG A;  4WHA A;  4WFO A;  1P6D A;  1IK3 A;  1RP1 A;  5FBA A;  1FGT A;  1YGE A;  2P0M A;  3V99 A;  5EEO A;  2PVS A;  1GYG A;  3V98 A;  3V92 A;  2IUJ A;  4JDG A;  1AK0 A;  2HUC A;  2PPL A;  1FGO A;  1FGM A;  2SBL A;  1RRH A;  1GPL A;  1LPA B;  3BND A;  3FG4 A;  5FB9 A;  1AH7 A;  1N8Q A;  1NO3 A;  4CWM A;  1FGR A;  1F8N A;  1Y4K A;  2WY6 A;  1OLP A;  2FNQ A;  3BNC A;  1BU8 A;  1P5X A;  3O8Y A;  3FG1 A;  1ROV A;  3PZW A;  2WXU A;  1CA1 A;  4DJ4 A;  1LOX A;  2FGN A;  1N8S A;  1P6E A;  3VF1 A;  3SNG A;  5FBF A;  3CWZ B;  5FBD A;  1RRL A;  4CXP A;  1W52 X;  2FFZ A;  2OXE A;  3BNE A;  1LPB B;  2WXT A;  2IUK A;  1FGQ A;  1KHO A;  1HPL A;  3W52 A;  4NRE A;  4CXV A;  5FBB A;  3BNB A;  4CXO A;  4QWT A;  1JNQ A;  1HU9 A;  1ETH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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