1KHOA

Crystal structure analysis of clostridium perfringens alpha-toxin isolated from avian strain swcp
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
370
structure length
370
Chain Sequence
WDGKADGTGTHAMIATQGVTILENDLSSNEPEVIRNNLEILKQNMHDLQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFTKDSKWYLSYSIPDTAESQIRKFSALARYEWKRGNYKQATFYLGEAMHYFGDADTPYHAANVTAVDSPGHVKFETFAEDRKDQYKINTTGSKTNDAFYSNILTNEDFNSWSKEFARSFAKTAKDLYYSHANMSCSWDEWDYAAKVALANSQKGTSGYIYRFLHDVSDGKDSSANKNVNELVAYITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDIQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium perfringens
molecule keywords alpha-toxin
total genus 141
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2001-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1khoA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1khoA02
1AK0A 3BNBA 1P5XA 5FBGA 2WXUA 1OLPA 1LPAB 1FGQA 3SNGA 4QWTA 4JDGA 4CXOA 5FBDA 1GYGA 1FGTA 2OXEA 1N8QA 3V92A 3CWZB 4CWMA 1JNQA 1RRHA 3FG1A 4CXVA 3V98A 1QM6A 3W52A 1LPBB 4NREA 1F8NA 1QMDA 1FGOA 1P6DA 2PVSA 1LNHA 2IUKA 2FFZA 2WY6A 1ROVA 3FG3A 1FGRA 2SBLA 5FB9A 1BU8A 1GPLA 2IUJA 1W52X 4WHAA 1HU9A 3V99A 2HUCA 5FBCA 3BNDA 1LOXA 1FGMA 1KHOA 5FBFA 1YGEA 3FG4A 3BNEA 3VF1A 4WFOA 1P6EA 5FBBA 1CA1A 5EEOA 3PZWA 3O8YA 1IK3A 2FGNA 1N8SA 5FBAA 2WXTA 4CXPA 1AH7A 2PPLA 1NO3A 1RP1A 1Y4KA 1RRLA 2FNQA 3BNCA 1HPLA 1ETHA 2P0MA 4DJ4A
chains in the Genus database with same CATH superfamily
1AK0A 3BNBA 1P5XA 5FBGA 2WXUA 1OLPA 1LPAB 3IBZA 2XHJA 2LRGA 1FGQA 3SNGA 4QWTA 4JDGA 4CXOA 5FBDA 1GYGA 1FGTA 2OXEA 3U6GA 1N8QA 2KXTA 3V92A 3CWZB 4CWMA 1JNQA 1RRHA 3FG1A 4CXVA 3V98A 1QM6A 3W52A 2LGEA 1LPBB 4NREA 1F8NA 1QMDA 1FGOA 1P6DA 2PVSA 1LNHA 2IUKA 2FFZA 2WY6A 1ROVA 3FG3A 1FGRA 2QNGA 2XFEA 2SBLA 5FB9A 1BU8A 1GPLA 2IUJA 1W52X 2XHHA 4QEYA 4WHAA 1HU9A 3V99A 2HUCA 5FBCA 3BNDA 1LOXA 1FGMA 1KHOA 5FBFA 2KXVA 2XFDA 1YGEA 3FG4A 3BNEA 3VF1A 4WFOA 1P6EA 5FBBA 1CA1A 5EEOA 3PZWA 3O8YA 1IK3A 2FGNA 1N8SA 5FBAA 2WXTA 4CXPA 1AH7A 2PPLA 1NO3A 1RP1A 2LG7A 1Y4KA 1RRLA 2FNQA 3BNCA 1HPLA 1ETHA 2P0MA 2QZ7A 4DJ4A
chains in the Genus database with same CATH topology
1AK0A 3BNBA 1P5XA 5FBGA 2WXUA 1OLPA 1LPAB 1FGQA 3SNGA 4QWTA 4JDGA 4CXOA 5FBDA 1GYGA 1FGTA 2OXEA 1N8QA 3V92A 3CWZB 4CWMA 1JNQA 1RRHA 3FG1A 4CXVA 3V98A 1QM6A 3W52A 1LPBB 4NREA 1F8NA 1QMDA 1FGOA 1P6DA 2PVSA 1LNHA 2IUKA 2FFZA 2WY6A 1ROVA 3FG3A 1FGRA 2SBLA 5FB9A 1BU8A 1GPLA 2IUJA 1W52X 4WHAA 1HU9A 3V99A 2HUCA 5FBCA 3BNDA 1LOXA 1FGMA 1KHOA 5FBFA 1YGEA 3FG4A 3BNEA 3VF1A 4WFOA 1P6EA 5FBBA 1CA1A 5EEOA 3PZWA 3O8YA 1IK3A 2FGNA 1N8SA 5FBAA 2WXTA 4CXPA 1AH7A 2PPLA 1NO3A 1RP1A 1Y4KA 1RRLA 2FNQA 3BNCA 1HPLA 1ETHA 2P0MA 4DJ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1AK0 A;  3BNB A;  1P5X A;  5FBG A;  2WXU A;  1OLP A;  1LPA B;  1FGQ A;  3SNG A;  4QWT A;  4JDG A;  4CXO A;  5FBD A;  1GYG A;  1FGT A;  2OXE A;  1N8Q A;  3V92 A;  3CWZ B;  4CWM A;  1JNQ A;  1RRH A;  3FG1 A;  4CXV A;  3V98 A;  1QM6 A;  3W52 A;  1LPB B;  4NRE A;  1F8N A;  1QMD A;  1FGO A;  1P6D A;  2PVS A;  1LNH A;  2IUK A;  2FFZ A;  2WY6 A;  1ROV A;  3FG3 A;  1FGR A;  2SBL A;  5FB9 A;  1BU8 A;  1GPL A;  2IUJ A;  1W52 X;  4WHA A;  1HU9 A;  3V99 A;  2HUC A;  5FBC A;  3BND A;  1LOX A;  1FGM A;  1KHO A;  5FBF A;  1YGE A;  3FG4 A;  3BNE A;  3VF1 A;  4WFO A;  1P6E A;  5FBB A;  1CA1 A;  5EEO A;  3PZW A;  3O8Y A;  1IK3 A;  2FGN A;  1N8S A;  5FBA A;  2WXT A;  4CXP A;  1AH7 A;  2PPL A;  1NO3 A;  1RP1 A;  1Y4K A;  1RRL A;  2FNQ A;  3BNC A;  1HPL A;  1ETH A;  2P0M A;  4DJ4 A; 
#chains in the Genus database with same CATH topology
 1AK0 A;  3BNB A;  1P5X A;  5FBG A;  2WXU A;  1OLP A;  1LPA B;  3IBZ A;  2XHJ A;  2LRG A;  1FGQ A;  3SNG A;  4QWT A;  4JDG A;  4CXO A;  5FBD A;  1GYG A;  1FGT A;  2OXE A;  3U6G A;  1N8Q A;  2KXT A;  3V92 A;  3CWZ B;  4CWM A;  1JNQ A;  1RRH A;  3FG1 A;  4CXV A;  3V98 A;  1QM6 A;  3W52 A;  2LGE A;  1LPB B;  4NRE A;  1F8N A;  1QMD A;  1FGO A;  1P6D A;  2PVS A;  1LNH A;  2IUK A;  2FFZ A;  2WY6 A;  1ROV A;  3FG3 A;  1FGR A;  2QNG A;  2XFE A;  2SBL A;  5FB9 A;  1BU8 A;  1GPL A;  2IUJ A;  1W52 X;  2XHH A;  4QEY A;  4WHA A;  1HU9 A;  3V99 A;  2HUC A;  5FBC A;  3BND A;  1LOX A;  1FGM A;  1KHO A;  5FBF A;  2KXV A;  2XFD A;  1YGE A;  3FG4 A;  3BNE A;  3VF1 A;  4WFO A;  1P6E A;  5FBB A;  1CA1 A;  5EEO A;  3PZW A;  3O8Y A;  1IK3 A;  2FGN A;  1N8S A;  5FBA A;  2WXT A;  4CXP A;  1AH7 A;  2PPL A;  1NO3 A;  1RP1 A;  2LG7 A;  1Y4K A;  1RRL A;  2FNQ A;  3BNC A;  1HPL A;  1ETH A;  2P0M A;  2QZ7 A;  4DJ4 A; 
#chains in the Genus database with same CATH homology
 1AK0 A;  3BNB A;  1P5X A;  5FBG A;  2WXU A;  1OLP A;  1LPA B;  1FGQ A;  3SNG A;  4QWT A;  4JDG A;  4CXO A;  5FBD A;  1GYG A;  1FGT A;  2OXE A;  1N8Q A;  3V92 A;  3CWZ B;  4CWM A;  1JNQ A;  1RRH A;  3FG1 A;  4CXV A;  3V98 A;  1QM6 A;  3W52 A;  1LPB B;  4NRE A;  1F8N A;  1QMD A;  1FGO A;  1P6D A;  2PVS A;  1LNH A;  2IUK A;  2FFZ A;  2WY6 A;  1ROV A;  3FG3 A;  1FGR A;  2SBL A;  5FB9 A;  1BU8 A;  1GPL A;  2IUJ A;  1W52 X;  4WHA A;  1HU9 A;  3V99 A;  2HUC A;  5FBC A;  3BND A;  1LOX A;  1FGM A;  1KHO A;  5FBF A;  1YGE A;  3FG4 A;  3BNE A;  3VF1 A;  4WFO A;  1P6E A;  5FBB A;  1CA1 A;  5EEO A;  3PZW A;  3O8Y A;  1IK3 A;  2FGN A;  1N8S A;  5FBA A;  2WXT A;  4CXP A;  1AH7 A;  2PPL A;  1NO3 A;  1RP1 A;  1Y4K A;  1RRL A;  2FNQ A;  3BNC A;  1HPL A;  1ETH A;  2P0M A;  4DJ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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