1KHOA

Crystal structure analysis of clostridium perfringens alpha-toxin isolated from avian strain swcp
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
370
structure length
370
Chain Sequence
WDGKADGTGTHAMIATQGVTILENDLSSNEPEVIRNNLEILKQNMHDLQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFTKDSKWYLSYSIPDTAESQIRKFSALARYEWKRGNYKQATFYLGEAMHYFGDADTPYHAANVTAVDSPGHVKFETFAEDRKDQYKINTTGSKTNDAFYSNILTNEDFNSWSKEFARSFAKTAKDLYYSHANMSCSWDEWDYAAKVALANSQKGTSGYIYRFLHDVSDGKDSSANKNVNELVAYITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDIQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium perfringens
molecule keywords alpha-toxin
total genus 141
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2001-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1khoA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1khoA02
4WHAA 5FBGA 1IK3A 5FBBA 2WXUA 1FGMA 1GPLA 3CWZB 1HPLA 2WXTA 2IUKA 1JNQA 1LPBB 1Y4KA 4CWMA 2P0MA 1N8SA 1P6EA 1W52X 2OXEA 1CA1A 3SNGA 3VF1A 1LNHA 5FB9A 4WFOA 3BNDA 1P5XA 1AH7A 3O8YA 3V99A 1HU9A 2WY6A 1YGEA 1P6DA 3V98A 5FBAA 1F8NA 1ETHA 1NO3A 4QWTA 4CXVA 5FBDA 2PPLA 2FNQA 1KHOA 3FG3A 3PZWA 5EEOA 1QM6A 1AK0A 4DJ4A 1N8QA 3FG1A 4JDGA 1OLPA 3FG4A 3W52A 5FBFA 1ROVA 1LPAB 1LOXA 3BNCA 4CXOA 3BNBA 2FFZA 1FGOA 2IUJA 1FGQA 4NREA 2FGNA 1QMDA 1GYGA 4CXPA 1RRHA 2SBLA 1RP1A 3BNEA 2PVSA 3V92A 1FGTA 5FBCA 1FGRA 2HUCA 1BU8A 1RRLA
chains in the Genus database with same CATH superfamily
4WHAA 5FBGA 2LRGA 2QNGA 4QEYA 1IK3A 5FBBA 2WXUA 1FGMA 1GPLA 3CWZB 1HPLA 2WXTA 2IUKA 1JNQA 1LPBB 1Y4KA 4CWMA 2P0MA 1N8SA 1P6EA 2XFDA 1W52X 2OXEA 2XHJA 1CA1A 2XHHA 3SNGA 3VF1A 1LNHA 5FB9A 4WFOA 3BNDA 1P5XA 1AH7A 2KXVA 3O8YA 3V99A 1HU9A 2WY6A 1YGEA 1P6DA 3V98A 5FBAA 1F8NA 1ETHA 1NO3A 4QWTA 4CXVA 2KXTA 5FBDA 2LG7A 2PPLA 2FNQA 2LGEA 1KHOA 3FG3A 3PZWA 5EEOA 1QM6A 1AK0A 4DJ4A 3U6GA 1N8QA 3FG1A 4JDGA 1OLPA 3FG4A 3W52A 5FBFA 3IBZA 1ROVA 1LPAB 1LOXA 3BNCA 4CXOA 3BNBA 2FFZA 1FGOA 2IUJA 1FGQA 4NREA 2FGNA 2QZ7A 2XFEA 1QMDA 1GYGA 4CXPA 1RRHA 2SBLA 1RP1A 3BNEA 2PVSA 3V92A 1FGTA 5FBCA 1FGRA 2HUCA 1BU8A 1RRLA
chains in the Genus database with same CATH topology
4WHAA 5FBGA 1IK3A 5FBBA 2WXUA 1FGMA 1GPLA 3CWZB 1HPLA 2WXTA 2IUKA 1JNQA 1LPBB 1Y4KA 4CWMA 2P0MA 1N8SA 1P6EA 1W52X 2OXEA 1CA1A 3SNGA 3VF1A 1LNHA 5FB9A 4WFOA 3BNDA 1P5XA 1AH7A 3O8YA 3V99A 1HU9A 2WY6A 1YGEA 1P6DA 3V98A 5FBAA 1F8NA 1ETHA 1NO3A 4QWTA 4CXVA 5FBDA 2PPLA 2FNQA 1KHOA 3FG3A 3PZWA 5EEOA 1QM6A 1AK0A 4DJ4A 1N8QA 3FG1A 4JDGA 1OLPA 3FG4A 3W52A 5FBFA 1ROVA 1LPAB 1LOXA 3BNCA 4CXOA 3BNBA 2FFZA 1FGOA 2IUJA 1FGQA 4NREA 2FGNA 1QMDA 1GYGA 4CXPA 1RRHA 2SBLA 1RP1A 3BNEA 2PVSA 3V92A 1FGTA 5FBCA 1FGRA 2HUCA 1BU8A 1RRLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WHA A;  5FBG A;  1IK3 A;  5FBB A;  2WXU A;  1FGM A;  1GPL A;  3CWZ B;  1HPL A;  2WXT A;  2IUK A;  1JNQ A;  1LPB B;  1Y4K A;  4CWM A;  2P0M A;  1N8S A;  1P6E A;  1W52 X;  2OXE A;  1CA1 A;  3SNG A;  3VF1 A;  1LNH A;  5FB9 A;  4WFO A;  3BND A;  1P5X A;  1AH7 A;  3O8Y A;  3V99 A;  1HU9 A;  2WY6 A;  1YGE A;  1P6D A;  3V98 A;  5FBA A;  1F8N A;  1ETH A;  1NO3 A;  4QWT A;  4CXV A;  5FBD A;  2PPL A;  2FNQ A;  1KHO A;  3FG3 A;  3PZW A;  5EEO A;  1QM6 A;  1AK0 A;  4DJ4 A;  1N8Q A;  3FG1 A;  4JDG A;  1OLP A;  3FG4 A;  3W52 A;  5FBF A;  1ROV A;  1LPA B;  1LOX A;  3BNC A;  4CXO A;  3BNB A;  2FFZ A;  1FGO A;  2IUJ A;  1FGQ A;  4NRE A;  2FGN A;  1QMD A;  1GYG A;  4CXP A;  1RRH A;  2SBL A;  1RP1 A;  3BNE A;  2PVS A;  3V92 A;  1FGT A;  5FBC A;  1FGR A;  2HUC A;  1BU8 A;  1RRL A; 
#chains in the Genus database with same CATH topology
 4WHA A;  5FBG A;  2LRG A;  2QNG A;  4QEY A;  1IK3 A;  5FBB A;  2WXU A;  1FGM A;  1GPL A;  3CWZ B;  1HPL A;  2WXT A;  2IUK A;  1JNQ A;  1LPB B;  1Y4K A;  4CWM A;  2P0M A;  1N8S A;  1P6E A;  2XFD A;  1W52 X;  2OXE A;  2XHJ A;  1CA1 A;  2XHH A;  3SNG A;  3VF1 A;  1LNH A;  5FB9 A;  4WFO A;  3BND A;  1P5X A;  1AH7 A;  2KXV A;  3O8Y A;  3V99 A;  1HU9 A;  2WY6 A;  1YGE A;  1P6D A;  3V98 A;  5FBA A;  1F8N A;  1ETH A;  1NO3 A;  4QWT A;  4CXV A;  2KXT A;  5FBD A;  2LG7 A;  2PPL A;  2FNQ A;  2LGE A;  1KHO A;  3FG3 A;  3PZW A;  5EEO A;  1QM6 A;  1AK0 A;  4DJ4 A;  3U6G A;  1N8Q A;  3FG1 A;  4JDG A;  1OLP A;  3FG4 A;  3W52 A;  5FBF A;  3IBZ A;  1ROV A;  1LPA B;  1LOX A;  3BNC A;  4CXO A;  3BNB A;  2FFZ A;  1FGO A;  2IUJ A;  1FGQ A;  4NRE A;  2FGN A;  2QZ7 A;  2XFE A;  1QMD A;  1GYG A;  4CXP A;  1RRH A;  2SBL A;  1RP1 A;  3BNE A;  2PVS A;  3V92 A;  1FGT A;  5FBC A;  1FGR A;  2HUC A;  1BU8 A;  1RRL A; 
#chains in the Genus database with same CATH homology
 4WHA A;  5FBG A;  1IK3 A;  5FBB A;  2WXU A;  1FGM A;  1GPL A;  3CWZ B;  1HPL A;  2WXT A;  2IUK A;  1JNQ A;  1LPB B;  1Y4K A;  4CWM A;  2P0M A;  1N8S A;  1P6E A;  1W52 X;  2OXE A;  1CA1 A;  3SNG A;  3VF1 A;  1LNH A;  5FB9 A;  4WFO A;  3BND A;  1P5X A;  1AH7 A;  3O8Y A;  3V99 A;  1HU9 A;  2WY6 A;  1YGE A;  1P6D A;  3V98 A;  5FBA A;  1F8N A;  1ETH A;  1NO3 A;  4QWT A;  4CXV A;  5FBD A;  2PPL A;  2FNQ A;  1KHO A;  3FG3 A;  3PZW A;  5EEO A;  1QM6 A;  1AK0 A;  4DJ4 A;  1N8Q A;  3FG1 A;  4JDG A;  1OLP A;  3FG4 A;  3W52 A;  5FBF A;  1ROV A;  1LPA B;  1LOX A;  3BNC A;  4CXO A;  3BNB A;  2FFZ A;  1FGO A;  2IUJ A;  1FGQ A;  4NRE A;  2FGN A;  1QMD A;  1GYG A;  4CXP A;  1RRH A;  2SBL A;  1RP1 A;  3BNE A;  2PVS A;  3V92 A;  1FGT A;  5FBC A;  1FGR A;  2HUC A;  1BU8 A;  1RRL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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