1KHOA

Crystal structure analysis of clostridium perfringens alpha-toxin isolated from avian strain swcp
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
370
structure length
370
Chain Sequence
WDGKADGTGTHAMIATQGVTILENDLSSNEPEVIRNNLEILKQNMHDLQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFTKDSKWYLSYSIPDTAESQIRKFSALARYEWKRGNYKQATFYLGEAMHYFGDADTPYHAANVTAVDSPGHVKFETFAEDRKDQYKINTTGSKTNDAFYSNILTNEDFNSWSKEFARSFAKTAKDLYYSHANMSCSWDEWDYAAKVALANSQKGTSGYIYRFLHDVSDGKDSSANKNVNELVAYITTGGEKYAGTDDYMYFGIKTKDGQTQEWTMDNPGNDFMTGSQDTYTFKLKDKNLKIDDIQNMWIRKSKYTEFGDDYKPANIKVIANGNVVLNKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties.
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium perfringens
molecule keywords alpha-toxin
total genus 141
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2001-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1khoA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1khoA02
4JDGA 3BNBA 1AK0A 1QMDA 1N8QA 1HU9A 2FFZA 1OLPA 1FGQA 1KHOA 1W52X 1F8NA 3BNEA 2FGNA 1RRHA 5FBDA 2OXEA 3V92A 5FBCA 2IUJA 1IK3A 4CWMA 4NREA 3FG1A 2FNQA 3PZWA 4CXOA 1ROVA 4WHAA 3W52A 5EEOA 1RRLA 2WXUA 5FB9A 1YGEA 2SBLA 3BNCA 3VF1A 1LOXA 1CA1A 2PVSA 1QM6A 4CXPA 1LPBB 3O8YA 5FBBA 4WFOA 2HUCA 3CWZB 2P0MA 4CXVA 1LPAB 5FBFA 1P6EA 1ETHA 3V98A 1AH7A 2WY6A 1LNHA 1GYGA 2PPLA 1N8SA 4QWTA 5FBGA 1FGMA 5FBAA 3FG3A 1FGOA 2IUKA 1Y4KA 1BU8A 1JNQA 3V99A 1FGTA 1GPLA 1FGRA 3SNGA 3BNDA 1P6DA 3FG4A 2WXTA 1P5XA 4DJ4A 1RP1A 1NO3A 1HPLA
chains in the Genus database with same CATH superfamily
4JDGA 2XHJA 3BNBA 1AK0A 1QMDA 1N8QA 1HU9A 2FFZA 1OLPA 1FGQA 1KHOA 3IBZA 1W52X 1F8NA 3BNEA 2FGNA 3U6GA 1RRHA 5FBDA 2OXEA 2XFEA 3V92A 5FBCA 2IUJA 1IK3A 4CWMA 4NREA 3FG1A 2FNQA 3PZWA 4CXOA 1ROVA 4WHAA 2LRGA 3W52A 5EEOA 1RRLA 2WXUA 5FB9A 1YGEA 4QEYA 2SBLA 3BNCA 3VF1A 1LOXA 1CA1A 2PVSA 1NO3A 1QM6A 4CXPA 2XHHA 1LPBB 3O8YA 2KXTA 5FBBA 4WFOA 2HUCA 3CWZB 2P0MA 4CXVA 1LPAB 5FBFA 1P6EA 1ETHA 3V98A 1AH7A 2XFDA 2LGEA 2WY6A 1LNHA 2KXVA 2LG7A 1GYGA 2PPLA 1N8SA 4QWTA 5FBGA 1FGMA 5FBAA 3FG3A 1FGOA 2IUKA 1Y4KA 1BU8A 1JNQA 3V99A 1FGTA 1GPLA 1FGRA 3SNGA 3BNDA 1P6DA 3FG4A 2WXTA 1P5XA 2QNGA 4DJ4A 1RP1A 2QZ7A 1HPLA
chains in the Genus database with same CATH topology
4JDGA 3BNBA 1AK0A 1QMDA 1N8QA 1HU9A 2FFZA 1OLPA 1FGQA 1KHOA 1W52X 1F8NA 3BNEA 2FGNA 1RRHA 5FBDA 2OXEA 3V92A 5FBCA 2IUJA 1IK3A 4CWMA 4NREA 3FG1A 2FNQA 3PZWA 4CXOA 1ROVA 4WHAA 3W52A 5EEOA 1RRLA 2WXUA 5FB9A 1YGEA 2SBLA 3BNCA 3VF1A 1LOXA 1CA1A 2PVSA 1QM6A 4CXPA 1LPBB 3O8YA 5FBBA 4WFOA 2HUCA 3CWZB 2P0MA 4CXVA 1LPAB 5FBFA 1P6EA 1ETHA 3V98A 1AH7A 2WY6A 1LNHA 1GYGA 2PPLA 1N8SA 4QWTA 5FBGA 1FGMA 5FBAA 3FG3A 1FGOA 2IUKA 1Y4KA 1BU8A 1JNQA 3V99A 1FGTA 1GPLA 1FGRA 3SNGA 3BNDA 1P6DA 3FG4A 2WXTA 1P5XA 4DJ4A 1RP1A 1NO3A 1HPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JDG A;  3BNB A;  1AK0 A;  1QMD A;  1N8Q A;  1HU9 A;  2FFZ A;  1OLP A;  1FGQ A;  1KHO A;  1W52 X;  1F8N A;  3BNE A;  2FGN A;  1RRH A;  5FBD A;  2OXE A;  3V92 A;  5FBC A;  2IUJ A;  1IK3 A;  4CWM A;  4NRE A;  3FG1 A;  2FNQ A;  3PZW A;  4CXO A;  1ROV A;  4WHA A;  3W52 A;  5EEO A;  1RRL A;  2WXU A;  5FB9 A;  1YGE A;  2SBL A;  3BNC A;  3VF1 A;  1LOX A;  1CA1 A;  2PVS A;  1QM6 A;  4CXP A;  1LPB B;  3O8Y A;  5FBB A;  4WFO A;  2HUC A;  3CWZ B;  2P0M A;  4CXV A;  1LPA B;  5FBF A;  1P6E A;  1ETH A;  3V98 A;  1AH7 A;  2WY6 A;  1LNH A;  1GYG A;  2PPL A;  1N8S A;  4QWT A;  5FBG A;  1FGM A;  5FBA A;  3FG3 A;  1FGO A;  2IUK A;  1Y4K A;  1BU8 A;  1JNQ A;  3V99 A;  1FGT A;  1GPL A;  1FGR A;  3SNG A;  3BND A;  1P6D A;  3FG4 A;  2WXT A;  1P5X A;  4DJ4 A;  1RP1 A;  1NO3 A;  1HPL A; 
#chains in the Genus database with same CATH topology
 4JDG A;  2XHJ A;  3BNB A;  1AK0 A;  1QMD A;  1N8Q A;  1HU9 A;  2FFZ A;  1OLP A;  1FGQ A;  1KHO A;  3IBZ A;  1W52 X;  1F8N A;  3BNE A;  2FGN A;  3U6G A;  1RRH A;  5FBD A;  2OXE A;  2XFE A;  3V92 A;  5FBC A;  2IUJ A;  1IK3 A;  4CWM A;  4NRE A;  3FG1 A;  2FNQ A;  3PZW A;  4CXO A;  1ROV A;  4WHA A;  2LRG A;  3W52 A;  5EEO A;  1RRL A;  2WXU A;  5FB9 A;  1YGE A;  4QEY A;  2SBL A;  3BNC A;  3VF1 A;  1LOX A;  1CA1 A;  2PVS A;  1NO3 A;  1QM6 A;  4CXP A;  2XHH A;  1LPB B;  3O8Y A;  2KXT A;  5FBB A;  4WFO A;  2HUC A;  3CWZ B;  2P0M A;  4CXV A;  1LPA B;  5FBF A;  1P6E A;  1ETH A;  3V98 A;  1AH7 A;  2XFD A;  2LGE A;  2WY6 A;  1LNH A;  2KXV A;  2LG7 A;  1GYG A;  2PPL A;  1N8S A;  4QWT A;  5FBG A;  1FGM A;  5FBA A;  3FG3 A;  1FGO A;  2IUK A;  1Y4K A;  1BU8 A;  1JNQ A;  3V99 A;  1FGT A;  1GPL A;  1FGR A;  3SNG A;  3BND A;  1P6D A;  3FG4 A;  2WXT A;  1P5X A;  2QNG A;  4DJ4 A;  1RP1 A;  2QZ7 A;  1HPL A; 
#chains in the Genus database with same CATH homology
 4JDG A;  3BNB A;  1AK0 A;  1QMD A;  1N8Q A;  1HU9 A;  2FFZ A;  1OLP A;  1FGQ A;  1KHO A;  1W52 X;  1F8N A;  3BNE A;  2FGN A;  1RRH A;  5FBD A;  2OXE A;  3V92 A;  5FBC A;  2IUJ A;  1IK3 A;  4CWM A;  4NRE A;  3FG1 A;  2FNQ A;  3PZW A;  4CXO A;  1ROV A;  4WHA A;  3W52 A;  5EEO A;  1RRL A;  2WXU A;  5FB9 A;  1YGE A;  2SBL A;  3BNC A;  3VF1 A;  1LOX A;  1CA1 A;  2PVS A;  1QM6 A;  4CXP A;  1LPB B;  3O8Y A;  5FBB A;  4WFO A;  2HUC A;  3CWZ B;  2P0M A;  4CXV A;  1LPA B;  5FBF A;  1P6E A;  1ETH A;  3V98 A;  1AH7 A;  2WY6 A;  1LNH A;  1GYG A;  2PPL A;  1N8S A;  4QWT A;  5FBG A;  1FGM A;  5FBA A;  3FG3 A;  1FGO A;  2IUK A;  1Y4K A;  1BU8 A;  1JNQ A;  3V99 A;  1FGT A;  1GPL A;  1FGR A;  3SNG A;  3BND A;  1P6D A;  3FG4 A;  2WXT A;  1P5X A;  4DJ4 A;  1RP1 A;  1NO3 A;  1HPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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