1KN9A

Crystal structure of a bacterial signal peptidase apo-enzyme, implications for signal peptide binding and the ser-lys dyad mechanism.
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
248
structure length
234
Chain Sequence
VRSFIYEPFQIPSGSMMPTLLIGDFILVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDPVSKELTIQPGCSSNALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETKENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGRATAIWMSFDLRLSRIGGIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli k12
molecule keywords Signal peptidase I
total genus 52
structure length 234
sequence length 248
chains with identical sequence B, C, D
ec nomenclature ec 3.4.21.89: Signal peptidase I.
pdb deposition date 2001-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00717 Peptidase_S24 Peptidase S24-like
A PF10502 Peptidase_S26 Signal peptidase, peptidase S26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.109.10 Mainly Beta Ribbon Umud Fragment, subunit A Umud Fragment, subunit A 1kn9A01
2.170.230.10 Mainly Beta Beta Complex Signal Peptidase I; Chain: A, domain 2 Signal Peptidase I; Chain: A, domain 2 1kn9A02
1JHHA 2FJRA 4NV4A 1B12A 2HNFA 3IIQA 4ME8A 2FKDA 4K8WA 1JHCA 1KN9A 1JHFA 1T7DA 2HO0A 3JSPA 1UMUA 1AY9A 3BDNA 3JSOA 1F39A 1JHEA 1KCAA 3K2ZA 1I4VA 3S04A 4N31A
chains in the Genus database with same CATH superfamily
1JHHA 2FJRA 4NV4A 1B12A 2HNFA 3IIQA 4ME8A 2FKDA 4K8WA 1JHCA 1KN9A 1JHFA 1T7DA 2HO0A 3JSPA 1UMUA 1AY9A 3BDNA 3JSOA 1F39A 1JHEA 1KCAA 3K2ZA 1I4VA 3S04A 4N31A
chains in the Genus database with same CATH topology
1JHHA 2FJRA 4NV4A 1B12A 2HNFA 3IIQA 4ME8A 2FKDA 4K8WA 1JHCA 1KN9A 1JHFA 1T7DA 2HO0A 3JSPA 1UMUA 1AY9A 3BDNA 3JSOA 1F39A 1JHEA 1KCAA 3K2ZA 1I4VA 3S04A 4N31A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JHH A;  2FJR A;  4NV4 A;  1B12 A;  2HNF A;  3IIQ A;  4ME8 A;  2FKD A;  4K8W A;  1JHC A;  1KN9 A;  1JHF A;  1T7D A;  2HO0 A;  3JSP A;  1UMU A;  1AY9 A;  3BDN A;  3JSO A;  1F39 A;  1JHE A;  1KCA A;  3K2Z A;  1I4V A;  3S04 A;  4N31 A; 
#chains in the Genus database with same CATH topology
 1JHH A;  2FJR A;  4NV4 A;  1B12 A;  2HNF A;  3IIQ A;  4ME8 A;  2FKD A;  4K8W A;  1JHC A;  1KN9 A;  1JHF A;  1T7D A;  2HO0 A;  3JSP A;  1UMU A;  1AY9 A;  3BDN A;  3JSO A;  1F39 A;  1JHE A;  1KCA A;  3K2Z A;  1I4V A;  3S04 A;  4N31 A; 
#chains in the Genus database with same CATH homology
 1JHH A;  2FJR A;  4NV4 A;  1B12 A;  2HNF A;  3IIQ A;  4ME8 A;  2FKD A;  4K8W A;  1JHC A;  1KN9 A;  1JHF A;  1T7D A;  2HO0 A;  3JSP A;  1UMU A;  1AY9 A;  3BDN A;  3JSO A;  1F39 A;  1JHE A;  1KCA A;  3K2Z A;  1I4V A;  3S04 A;  4N31 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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