1OLPA

Alpha toxin from clostridium absonum
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
370
structure length
370
Chain Sequence
WDGKEDGTGTHSVIVTQAIEMLKHDLSKDEPEAIRNDLSILEKNLHKFQLGSTFPDYDPNAYSLYQDHFWDPDTDHNFTQDNKWYLSYAVPDNAESQTRKFATLAKNEWDKGNYEKAAWYLGQGMHYFGDLNTPYHAANVTAVDSPGHVKFETYAEERKDTYRLDTTGYNTDDAFYKDTLKNDNFNEWSKGYCKYWAKKAKNLYYSHATMSNSWDDWEYAASHGVGNAQKGVAGYLYRFLNDVSNKDAVDKDYDLNEIVVMIKTADVQDAGTDNYIYFGIETKDGVKEEWALDNPGNDFTRNQEGTYTLKLKNKNTKYSDIKNMWIRDEKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Clostridium Absonum Alpha-Toxin: New Insights Into Clostridial Phospholipase C Substrate Binding and Specificity
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium sardiniense
molecule keywords ALPHA-TOXIN
total genus 136
structure length 370
sequence length 370
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2003-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1olpA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1olpA02
1BU8A 1LPAB 4QWTA 3VF1A 2WXTA 5FB9A 3W52A 1FGQA 5FBCA 1QM6A 5FBFA 3BNDA 3FG1A 1RP1A 1AH7A 3V92A 1LPBB 2WXUA 1LNHA 2SBLA 1CA1A 1JNQA 3SNGA 1P6EA 4CXVA 3PZWA 5FBGA 5FBBA 1RRLA 3BNEA 2WY6A 3V99A 1N8SA 1P6DA 1NO3A 3BNBA 5EEOA 2FNQA 1IK3A 3CWZB 2PPLA 2FFZA 1YGEA 1N8QA 5FBDA 2PVSA 1GPLA 1LOXA 4CWMA 4NREA 1HU9A 1F8NA 1HPLA 1FGRA 2FGNA 3FG3A 1GYGA 1W52X 1FGOA 1ETHA 1P5XA 3V98A 4JDGA 4WFOA 4CXOA 2HUCA 1FGTA 1AK0A 1ROVA 2IUJA 4DJ4A 3BNCA 1KHOA 2OXEA 2IUKA 3O8YA 1RRHA 1OLPA 1QMDA 4CXPA 3FG4A 5FBAA 1Y4KA 4WHAA 1FGMA 2P0MA
chains in the Genus database with same CATH superfamily
1BU8A 1LPAB 4QWTA 3VF1A 2WXTA 5FB9A 3W52A 1FGQA 5FBCA 1QM6A 5FBFA 3BNDA 3FG1A 1RP1A 1AH7A 3V92A 2QNGA 1LPBB 2XHHA 2WXUA 1LNHA 2XHJA 2KXTA 2SBLA 1CA1A 1JNQA 4QEYA 2XFDA 3SNGA 1P6EA 4CXVA 3PZWA 5FBGA 5FBBA 1RRLA 3BNEA 2LG7A 2WY6A 3V99A 1N8SA 1P6DA 2LGEA 1NO3A 3BNBA 2XFEA 2LRGA 5EEOA 2FNQA 1IK3A 3CWZB 2PPLA 2FFZA 1YGEA 1N8QA 5FBDA 2PVSA 1GPLA 1LOXA 4CWMA 4NREA 1HU9A 1F8NA 3IBZA 1HPLA 1FGRA 2FGNA 3U6GA 3FG3A 1GYGA 1W52X 1FGOA 2KXVA 1ETHA 1P5XA 3V98A 4JDGA 4WFOA 4CXOA 2HUCA 1FGTA 1AK0A 1ROVA 2IUJA 4DJ4A 3BNCA 1KHOA 2OXEA 2IUKA 3O8YA 1RRHA 1OLPA 1QMDA 4CXPA 3FG4A 5FBAA 2QZ7A 1Y4KA 4WHAA 1FGMA 2P0MA
chains in the Genus database with same CATH topology
1BU8A 1LPAB 4QWTA 3VF1A 2WXTA 5FB9A 3W52A 1FGQA 5FBCA 1QM6A 5FBFA 3BNDA 3FG1A 1RP1A 1AH7A 3V92A 1LPBB 2WXUA 1LNHA 2SBLA 1CA1A 1JNQA 3SNGA 1P6EA 4CXVA 3PZWA 5FBGA 5FBBA 1RRLA 3BNEA 2WY6A 3V99A 1N8SA 1P6DA 1NO3A 3BNBA 5EEOA 2FNQA 1IK3A 3CWZB 2PPLA 2FFZA 1YGEA 1N8QA 5FBDA 2PVSA 1GPLA 1LOXA 4CWMA 4NREA 1HU9A 1F8NA 1HPLA 1FGRA 2FGNA 3FG3A 1GYGA 1W52X 1FGOA 1ETHA 1P5XA 3V98A 4JDGA 4WFOA 4CXOA 2HUCA 1FGTA 1AK0A 1ROVA 2IUJA 4DJ4A 3BNCA 1KHOA 2OXEA 2IUKA 3O8YA 1RRHA 1OLPA 1QMDA 4CXPA 3FG4A 5FBAA 1Y4KA 4WHAA 1FGMA 2P0MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BU8 A;  1LPA B;  4QWT A;  3VF1 A;  2WXT A;  5FB9 A;  3W52 A;  1FGQ A;  5FBC A;  1QM6 A;  5FBF A;  3BND A;  3FG1 A;  1RP1 A;  1AH7 A;  3V92 A;  1LPB B;  2WXU A;  1LNH A;  2SBL A;  1CA1 A;  1JNQ A;  3SNG A;  1P6E A;  4CXV A;  3PZW A;  5FBG A;  5FBB A;  1RRL A;  3BNE A;  2WY6 A;  3V99 A;  1N8S A;  1P6D A;  1NO3 A;  3BNB A;  5EEO A;  2FNQ A;  1IK3 A;  3CWZ B;  2PPL A;  2FFZ A;  1YGE A;  1N8Q A;  5FBD A;  2PVS A;  1GPL A;  1LOX A;  4CWM A;  4NRE A;  1HU9 A;  1F8N A;  1HPL A;  1FGR A;  2FGN A;  3FG3 A;  1GYG A;  1W52 X;  1FGO A;  1ETH A;  1P5X A;  3V98 A;  4JDG A;  4WFO A;  4CXO A;  2HUC A;  1FGT A;  1AK0 A;  1ROV A;  2IUJ A;  4DJ4 A;  3BNC A;  1KHO A;  2OXE A;  2IUK A;  3O8Y A;  1RRH A;  1OLP A;  1QMD A;  4CXP A;  3FG4 A;  5FBA A;  1Y4K A;  4WHA A;  1FGM A;  2P0M A; 
#chains in the Genus database with same CATH topology
 1BU8 A;  1LPA B;  4QWT A;  3VF1 A;  2WXT A;  5FB9 A;  3W52 A;  1FGQ A;  5FBC A;  1QM6 A;  5FBF A;  3BND A;  3FG1 A;  1RP1 A;  1AH7 A;  3V92 A;  2QNG A;  1LPB B;  2XHH A;  2WXU A;  1LNH A;  2XHJ A;  2KXT A;  2SBL A;  1CA1 A;  1JNQ A;  4QEY A;  2XFD A;  3SNG A;  1P6E A;  4CXV A;  3PZW A;  5FBG A;  5FBB A;  1RRL A;  3BNE A;  2LG7 A;  2WY6 A;  3V99 A;  1N8S A;  1P6D A;  2LGE A;  1NO3 A;  3BNB A;  2XFE A;  2LRG A;  5EEO A;  2FNQ A;  1IK3 A;  3CWZ B;  2PPL A;  2FFZ A;  1YGE A;  1N8Q A;  5FBD A;  2PVS A;  1GPL A;  1LOX A;  4CWM A;  4NRE A;  1HU9 A;  1F8N A;  3IBZ A;  1HPL A;  1FGR A;  2FGN A;  3U6G A;  3FG3 A;  1GYG A;  1W52 X;  1FGO A;  2KXV A;  1ETH A;  1P5X A;  3V98 A;  4JDG A;  4WFO A;  4CXO A;  2HUC A;  1FGT A;  1AK0 A;  1ROV A;  2IUJ A;  4DJ4 A;  3BNC A;  1KHO A;  2OXE A;  2IUK A;  3O8Y A;  1RRH A;  1OLP A;  1QMD A;  4CXP A;  3FG4 A;  5FBA A;  2QZ7 A;  1Y4K A;  4WHA A;  1FGM A;  2P0M A; 
#chains in the Genus database with same CATH homology
 1BU8 A;  1LPA B;  4QWT A;  3VF1 A;  2WXT A;  5FB9 A;  3W52 A;  1FGQ A;  5FBC A;  1QM6 A;  5FBF A;  3BND A;  3FG1 A;  1RP1 A;  1AH7 A;  3V92 A;  1LPB B;  2WXU A;  1LNH A;  2SBL A;  1CA1 A;  1JNQ A;  3SNG A;  1P6E A;  4CXV A;  3PZW A;  5FBG A;  5FBB A;  1RRL A;  3BNE A;  2WY6 A;  3V99 A;  1N8S A;  1P6D A;  1NO3 A;  3BNB A;  5EEO A;  2FNQ A;  1IK3 A;  3CWZ B;  2PPL A;  2FFZ A;  1YGE A;  1N8Q A;  5FBD A;  2PVS A;  1GPL A;  1LOX A;  4CWM A;  4NRE A;  1HU9 A;  1F8N A;  1HPL A;  1FGR A;  2FGN A;  3FG3 A;  1GYG A;  1W52 X;  1FGO A;  1ETH A;  1P5X A;  3V98 A;  4JDG A;  4WFO A;  4CXO A;  2HUC A;  1FGT A;  1AK0 A;  1ROV A;  2IUJ A;  4DJ4 A;  3BNC A;  1KHO A;  2OXE A;  2IUK A;  3O8Y A;  1RRH A;  1OLP A;  1QMD A;  4CXP A;  3FG4 A;  5FBA A;  1Y4K A;  4WHA A;  1FGM A;  2P0M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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