1OLPA

Alpha toxin from clostridium absonum
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
370
structure length
370
Chain Sequence
WDGKEDGTGTHSVIVTQAIEMLKHDLSKDEPEAIRNDLSILEKNLHKFQLGSTFPDYDPNAYSLYQDHFWDPDTDHNFTQDNKWYLSYAVPDNAESQTRKFATLAKNEWDKGNYEKAAWYLGQGMHYFGDLNTPYHAANVTAVDSPGHVKFETYAEERKDTYRLDTTGYNTDDAFYKDTLKNDNFNEWSKGYCKYWAKKAKNLYYSHATMSNSWDDWEYAASHGVGNAQKGVAGYLYRFLNDVSNKDAVDKDYDLNEIVVMIKTADVQDAGTDNYIYFGIETKDGVKEEWALDNPGNDFTRNQEGTYTLKLKNKNTKYSDIKNMWIRDEKLTVATDGWKPSYVKVIAGDKVRLEKNINEWISGGTTYTLK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Clostridium Absonum Alpha-Toxin: New Insights Into Clostridial Phospholipase C Substrate Binding and Specificity
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium sardiniense
molecule keywords ALPHA-TOXIN
total genus 136
structure length 370
sequence length 370
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2003-08-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1olpA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1olpA02
3BNEA 2FFZA 3PZWA 1P6DA 1JNQA 1IK3A 1RRLA 1N8SA 4QWTA 3V98A 2WXUA 1N8QA 1LOXA 3FG1A 2FNQA 1YGEA 4CXVA 1Y4KA 3V99A 2WY6A 5FBCA 1AK0A 3CWZB 3BNDA 1OLPA 3BNCA 3SNGA 1HU9A 3BNBA 1ETHA 3W52A 1P6EA 1GPLA 1KHOA 1GYGA 5EEOA 4CXOA 1FGQA 5FBDA 5FBGA 2PVSA 1RP1A 2FGNA 2P0MA 1W52X 2PPLA 3VF1A 2WXTA 1FGMA 1LPBB 3V92A 2IUKA 2OXEA 2IUJA 1P5XA 3FG3A 4WHAA 4DJ4A 1LPAB 1FGRA 4CXPA 4CWMA 2HUCA 5FBFA 1FGTA 5FBAA 4JDGA 1CA1A 1QM6A 2SBLA 3FG4A 1LNHA 1BU8A 5FB9A 1RRHA 4NREA 5FBBA 1FGOA 1F8NA 1QMDA 1AH7A 3O8YA 4WFOA 1HPLA 1NO3A 1ROVA
chains in the Genus database with same CATH superfamily
3BNEA 2FFZA 3PZWA 1P6DA 1JNQA 1IK3A 1RRLA 1N8SA 4QWTA 3V98A 2WXUA 1N8QA 1LOXA 3FG1A 2FNQA 1YGEA 4CXVA 1Y4KA 3V99A 2WY6A 2LGEA 5FBCA 1AK0A 3CWZB 3BNDA 1OLPA 3BNCA 3SNGA 1HU9A 3BNBA 1ETHA 3W52A 2XFEA 4QEYA 1P6EA 1GPLA 1KHOA 1GYGA 5EEOA 4CXOA 1FGQA 5FBDA 5FBGA 2PVSA 1RP1A 2FGNA 2P0MA 1W52X 2PPLA 3VF1A 2WXTA 1FGMA 1LPBB 2QNGA 3V92A 2IUKA 2OXEA 2IUJA 1P5XA 3FG3A 2KXTA 2XHJA 4WHAA 4DJ4A 2QZ7A 2XFDA 3IBZA 1LPAB 2KXVA 3U6GA 1FGRA 4CXPA 4CWMA 2HUCA 5FBFA 1FGTA 5FBAA 4JDGA 1CA1A 1QM6A 2SBLA 3FG4A 1LNHA 1BU8A 5FB9A 1RRHA 4NREA 5FBBA 1FGOA 1F8NA 1QMDA 2LRGA 1AH7A 2LG7A 2XHHA 3O8YA 4WFOA 1HPLA 1NO3A 1ROVA
chains in the Genus database with same CATH topology
3BNEA 2FFZA 3PZWA 1P6DA 1JNQA 1IK3A 1RRLA 1N8SA 4QWTA 3V98A 2WXUA 1N8QA 1LOXA 3FG1A 2FNQA 1YGEA 4CXVA 1Y4KA 3V99A 2WY6A 5FBCA 1AK0A 3CWZB 3BNDA 1OLPA 3BNCA 3SNGA 1HU9A 3BNBA 1ETHA 3W52A 1P6EA 1GPLA 1KHOA 1GYGA 5EEOA 4CXOA 1FGQA 5FBDA 5FBGA 2PVSA 1RP1A 2FGNA 2P0MA 1W52X 2PPLA 3VF1A 2WXTA 1FGMA 1LPBB 3V92A 2IUKA 2OXEA 2IUJA 1P5XA 3FG3A 4WHAA 4DJ4A 1LPAB 1FGRA 4CXPA 4CWMA 2HUCA 5FBFA 1FGTA 5FBAA 4JDGA 1CA1A 1QM6A 2SBLA 3FG4A 1LNHA 1BU8A 5FB9A 1RRHA 4NREA 5FBBA 1FGOA 1F8NA 1QMDA 1AH7A 3O8YA 4WFOA 1HPLA 1NO3A 1ROVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BNE A;  2FFZ A;  3PZW A;  1P6D A;  1JNQ A;  1IK3 A;  1RRL A;  1N8S A;  4QWT A;  3V98 A;  2WXU A;  1N8Q A;  1LOX A;  3FG1 A;  2FNQ A;  1YGE A;  4CXV A;  1Y4K A;  3V99 A;  2WY6 A;  5FBC A;  1AK0 A;  3CWZ B;  3BND A;  1OLP A;  3BNC A;  3SNG A;  1HU9 A;  3BNB A;  1ETH A;  3W52 A;  1P6E A;  1GPL A;  1KHO A;  1GYG A;  5EEO A;  4CXO A;  1FGQ A;  5FBD A;  5FBG A;  2PVS A;  1RP1 A;  2FGN A;  2P0M A;  1W52 X;  2PPL A;  3VF1 A;  2WXT A;  1FGM A;  1LPB B;  3V92 A;  2IUK A;  2OXE A;  2IUJ A;  1P5X A;  3FG3 A;  4WHA A;  4DJ4 A;  1LPA B;  1FGR A;  4CXP A;  4CWM A;  2HUC A;  5FBF A;  1FGT A;  5FBA A;  4JDG A;  1CA1 A;  1QM6 A;  2SBL A;  3FG4 A;  1LNH A;  1BU8 A;  5FB9 A;  1RRH A;  4NRE A;  5FBB A;  1FGO A;  1F8N A;  1QMD A;  1AH7 A;  3O8Y A;  4WFO A;  1HPL A;  1NO3 A;  1ROV A; 
#chains in the Genus database with same CATH topology
 3BNE A;  2FFZ A;  3PZW A;  1P6D A;  1JNQ A;  1IK3 A;  1RRL A;  1N8S A;  4QWT A;  3V98 A;  2WXU A;  1N8Q A;  1LOX A;  3FG1 A;  2FNQ A;  1YGE A;  4CXV A;  1Y4K A;  3V99 A;  2WY6 A;  2LGE A;  5FBC A;  1AK0 A;  3CWZ B;  3BND A;  1OLP A;  3BNC A;  3SNG A;  1HU9 A;  3BNB A;  1ETH A;  3W52 A;  2XFE A;  4QEY A;  1P6E A;  1GPL A;  1KHO A;  1GYG A;  5EEO A;  4CXO A;  1FGQ A;  5FBD A;  5FBG A;  2PVS A;  1RP1 A;  2FGN A;  2P0M A;  1W52 X;  2PPL A;  3VF1 A;  2WXT A;  1FGM A;  1LPB B;  2QNG A;  3V92 A;  2IUK A;  2OXE A;  2IUJ A;  1P5X A;  3FG3 A;  2KXT A;  2XHJ A;  4WHA A;  4DJ4 A;  2QZ7 A;  2XFD A;  3IBZ A;  1LPA B;  2KXV A;  3U6G A;  1FGR A;  4CXP A;  4CWM A;  2HUC A;  5FBF A;  1FGT A;  5FBA A;  4JDG A;  1CA1 A;  1QM6 A;  2SBL A;  3FG4 A;  1LNH A;  1BU8 A;  5FB9 A;  1RRH A;  4NRE A;  5FBB A;  1FGO A;  1F8N A;  1QMD A;  2LRG A;  1AH7 A;  2LG7 A;  2XHH A;  3O8Y A;  4WFO A;  1HPL A;  1NO3 A;  1ROV A; 
#chains in the Genus database with same CATH homology
 3BNE A;  2FFZ A;  3PZW A;  1P6D A;  1JNQ A;  1IK3 A;  1RRL A;  1N8S A;  4QWT A;  3V98 A;  2WXU A;  1N8Q A;  1LOX A;  3FG1 A;  2FNQ A;  1YGE A;  4CXV A;  1Y4K A;  3V99 A;  2WY6 A;  5FBC A;  1AK0 A;  3CWZ B;  3BND A;  1OLP A;  3BNC A;  3SNG A;  1HU9 A;  3BNB A;  1ETH A;  3W52 A;  1P6E A;  1GPL A;  1KHO A;  1GYG A;  5EEO A;  4CXO A;  1FGQ A;  5FBD A;  5FBG A;  2PVS A;  1RP1 A;  2FGN A;  2P0M A;  1W52 X;  2PPL A;  3VF1 A;  2WXT A;  1FGM A;  1LPB B;  3V92 A;  2IUK A;  2OXE A;  2IUJ A;  1P5X A;  3FG3 A;  4WHA A;  4DJ4 A;  1LPA B;  1FGR A;  4CXP A;  4CWM A;  2HUC A;  5FBF A;  1FGT A;  5FBA A;  4JDG A;  1CA1 A;  1QM6 A;  2SBL A;  3FG4 A;  1LNH A;  1BU8 A;  5FB9 A;  1RRH A;  4NRE A;  5FBB A;  1FGO A;  1F8N A;  1QMD A;  1AH7 A;  3O8Y A;  4WFO A;  1HPL A;  1NO3 A;  1ROV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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