1QMDA

Calcium bound closed form alpha-toxin from clostridium perfringens
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
370
structure length
370
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterisation of the Calcium-Binding C-Terminal Domain of Clostridium Perfringens Alpha-Toxin
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 137
structure length 370
sequence length 370
chains with identical sequence B
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 1999-09-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 1qmdA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 1qmdA02
1FGTA 3BNCA 2P0MA 3CWZB 4CXOA 2IUKA 4NREA 1LPAB 1P5XA 3BNBA 3BNEA 2IUJA 1QMDA 3SNGA 3FG1A 4DJ4A 3BNDA 4CWMA 1IK3A 2WXTA 1KHOA 1N8QA 1AH7A 1FGQA 3V99A 1HU9A 1JNQA 1LOXA 1ETHA 1GYGA 1FGRA 5FBFA 1QM6A 5FBCA 1RRHA 2PPLA 1CA1A 1LPBB 3W52A 4CXVA 3O8YA 5FBAA 3V92A 2FNQA 2SBLA 2HUCA 1HPLA 5FB9A 1RP1A 2OXEA 1NO3A 2FGNA 1ROVA 1Y4KA 1LNHA 4WFOA 3FG4A 5FBGA 3FG3A 1W52X 1GPLA 4QWTA 3V98A 1P6EA 1AK0A 1OLPA 1BU8A 3PZWA 1FGOA 2FFZA 3VF1A 5FBDA 2WY6A 2WXUA 2PVSA 4CXPA 1F8NA 5FBBA 1N8SA 1FGMA 4WHAA 4JDGA 1RRLA 1YGEA 5EEOA 1P6DA
chains in the Genus database with same CATH superfamily
1FGTA 2LGEA 3BNCA 2P0MA 3CWZB 4CXOA 2IUKA 4NREA 1LPAB 2KXVA 1P5XA 3BNBA 3BNEA 2IUJA 1QMDA 3SNGA 3FG1A 4DJ4A 3BNDA 4CWMA 1IK3A 2KXTA 2WXTA 1KHOA 1N8QA 1AH7A 2QZ7A 1FGQA 3V99A 1HU9A 1JNQA 1LOXA 1ETHA 1GYGA 3U6GA 1FGRA 5FBFA 1QM6A 5FBCA 1RRHA 2PPLA 1CA1A 1LPBB 2LG7A 3W52A 2QNGA 4CXVA 3O8YA 5FBAA 3V92A 3IBZA 2FNQA 2SBLA 2HUCA 1HPLA 5FB9A 1RP1A 2OXEA 1NO3A 2FGNA 1ROVA 1Y4KA 1LNHA 2XFDA 4WFOA 3FG4A 5FBGA 2LRGA 3FG3A 1W52X 1GPLA 4QWTA 3V98A 1P6EA 1AK0A 1OLPA 2XHJA 1BU8A 4QEYA 3PZWA 1FGOA 2FFZA 3VF1A 5FBDA 2WY6A 2XFEA 2WXUA 2PVSA 4CXPA 1F8NA 5FBBA 1N8SA 1FGMA 4WHAA 4JDGA 1RRLA 1YGEA 5EEOA 2XHHA 1P6DA
chains in the Genus database with same CATH topology
1FGTA 3BNCA 2P0MA 3CWZB 4CXOA 2IUKA 4NREA 1LPAB 1P5XA 3BNBA 3BNEA 2IUJA 1QMDA 3SNGA 3FG1A 4DJ4A 3BNDA 4CWMA 1IK3A 2WXTA 1KHOA 1N8QA 1AH7A 1FGQA 3V99A 1HU9A 1JNQA 1LOXA 1ETHA 1GYGA 1FGRA 5FBFA 1QM6A 5FBCA 1RRHA 2PPLA 1CA1A 1LPBB 3W52A 4CXVA 3O8YA 5FBAA 3V92A 2FNQA 2SBLA 2HUCA 1HPLA 5FB9A 1RP1A 2OXEA 1NO3A 2FGNA 1ROVA 1Y4KA 1LNHA 4WFOA 3FG4A 5FBGA 3FG3A 1W52X 1GPLA 4QWTA 3V98A 1P6EA 1AK0A 1OLPA 1BU8A 3PZWA 1FGOA 2FFZA 3VF1A 5FBDA 2WY6A 2WXUA 2PVSA 4CXPA 1F8NA 5FBBA 1N8SA 1FGMA 4WHAA 4JDGA 1RRLA 1YGEA 5EEOA 1P6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1FGT A;  3BNC A;  2P0M A;  3CWZ B;  4CXO A;  2IUK A;  4NRE A;  1LPA B;  1P5X A;  3BNB A;  3BNE A;  2IUJ A;  1QMD A;  3SNG A;  3FG1 A;  4DJ4 A;  3BND A;  4CWM A;  1IK3 A;  2WXT A;  1KHO A;  1N8Q A;  1AH7 A;  1FGQ A;  3V99 A;  1HU9 A;  1JNQ A;  1LOX A;  1ETH A;  1GYG A;  1FGR A;  5FBF A;  1QM6 A;  5FBC A;  1RRH A;  2PPL A;  1CA1 A;  1LPB B;  3W52 A;  4CXV A;  3O8Y A;  5FBA A;  3V92 A;  2FNQ A;  2SBL A;  2HUC A;  1HPL A;  5FB9 A;  1RP1 A;  2OXE A;  1NO3 A;  2FGN A;  1ROV A;  1Y4K A;  1LNH A;  4WFO A;  3FG4 A;  5FBG A;  3FG3 A;  1W52 X;  1GPL A;  4QWT A;  3V98 A;  1P6E A;  1AK0 A;  1OLP A;  1BU8 A;  3PZW A;  1FGO A;  2FFZ A;  3VF1 A;  5FBD A;  2WY6 A;  2WXU A;  2PVS A;  4CXP A;  1F8N A;  5FBB A;  1N8S A;  1FGM A;  4WHA A;  4JDG A;  1RRL A;  1YGE A;  5EEO A;  1P6D A; 
#chains in the Genus database with same CATH topology
 1FGT A;  2LGE A;  3BNC A;  2P0M A;  3CWZ B;  4CXO A;  2IUK A;  4NRE A;  1LPA B;  2KXV A;  1P5X A;  3BNB A;  3BNE A;  2IUJ A;  1QMD A;  3SNG A;  3FG1 A;  4DJ4 A;  3BND A;  4CWM A;  1IK3 A;  2KXT A;  2WXT A;  1KHO A;  1N8Q A;  1AH7 A;  2QZ7 A;  1FGQ A;  3V99 A;  1HU9 A;  1JNQ A;  1LOX A;  1ETH A;  1GYG A;  3U6G A;  1FGR A;  5FBF A;  1QM6 A;  5FBC A;  1RRH A;  2PPL A;  1CA1 A;  1LPB B;  2LG7 A;  3W52 A;  2QNG A;  4CXV A;  3O8Y A;  5FBA A;  3V92 A;  3IBZ A;  2FNQ A;  2SBL A;  2HUC A;  1HPL A;  5FB9 A;  1RP1 A;  2OXE A;  1NO3 A;  2FGN A;  1ROV A;  1Y4K A;  1LNH A;  2XFD A;  4WFO A;  3FG4 A;  5FBG A;  2LRG A;  3FG3 A;  1W52 X;  1GPL A;  4QWT A;  3V98 A;  1P6E A;  1AK0 A;  1OLP A;  2XHJ A;  1BU8 A;  4QEY A;  3PZW A;  1FGO A;  2FFZ A;  3VF1 A;  5FBD A;  2WY6 A;  2XFE A;  2WXU A;  2PVS A;  4CXP A;  1F8N A;  5FBB A;  1N8S A;  1FGM A;  4WHA A;  4JDG A;  1RRL A;  1YGE A;  5EEO A;  2XHH A;  1P6D A; 
#chains in the Genus database with same CATH homology
 1FGT A;  3BNC A;  2P0M A;  3CWZ B;  4CXO A;  2IUK A;  4NRE A;  1LPA B;  1P5X A;  3BNB A;  3BNE A;  2IUJ A;  1QMD A;  3SNG A;  3FG1 A;  4DJ4 A;  3BND A;  4CWM A;  1IK3 A;  2WXT A;  1KHO A;  1N8Q A;  1AH7 A;  1FGQ A;  3V99 A;  1HU9 A;  1JNQ A;  1LOX A;  1ETH A;  1GYG A;  1FGR A;  5FBF A;  1QM6 A;  5FBC A;  1RRH A;  2PPL A;  1CA1 A;  1LPB B;  3W52 A;  4CXV A;  3O8Y A;  5FBA A;  3V92 A;  2FNQ A;  2SBL A;  2HUC A;  1HPL A;  5FB9 A;  1RP1 A;  2OXE A;  1NO3 A;  2FGN A;  1ROV A;  1Y4K A;  1LNH A;  4WFO A;  3FG4 A;  5FBG A;  3FG3 A;  1W52 X;  1GPL A;  4QWT A;  3V98 A;  1P6E A;  1AK0 A;  1OLP A;  1BU8 A;  3PZW A;  1FGO A;  2FFZ A;  3VF1 A;  5FBD A;  2WY6 A;  2WXU A;  2PVS A;  4CXP A;  1F8N A;  5FBB A;  1N8S A;  1FGM A;  4WHA A;  4JDG A;  1RRL A;  1YGE A;  5EEO A;  1P6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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