1RZYA

Crystal structure of rabbit hint complexed with n-ethylsulfamoyladenosine
Total Genus 28
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
28
sequence length
114
structure length
114
Chain Sequence
PGGDTIFGKIIRKEIPAKIIFEDDQCLAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKCAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical, crystallographic, and mutagenic characterization of hint, the AMP-lysine hydrolase, with novel substrates and inhibitors
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 28
structure length 114
sequence length 114
ec nomenclature
pdb deposition date 2003-12-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 1rzyA00
5IPDA 1GUQA 1HXQA 3IMIA 1KPCA 1EMSA 1Z84A 3O0MA 3LB5A 4NJXA 3RHNA 4INIA 2Q4LA 4NDIA 1VLRA 5ED3A 5I2EA 1ST0A 3O1ZA 3NRDA 3SPLA 1ST4A 3BL9A 4XBAA 5IPCA 4RHNA 4NDGA 3O1XA 5IPEA 5I2FA 1XMLA 5BV3A 4ZGLA 5FITA 1HXPA 4NDHA 3FITA 2EO4A 4EGUA 1ZWJA 2H39A 3BLAA 4EQGA 4QDEA 2OIKA 3OXKA 4INCA 3N1SA 3L7XA 5EMTA 5RHNA 1Y23A 4NK0A 4EQHA 2FITA 4NJZA 4NJYA 5CS2A 5ED6A 4YKLB 1FHIA 4QEBA 4ZKVA 3R6FA 3SP4A 3I4SA 3OMFA 3QGZA 1KPBA 3OHEA 3SZQA 2FHIA 1KPEA 3P0TA 1KPFA 5IN3A 3TW2A 4ZKLA 1GUPA 3N1TA 1FITA 6RHNA 3KSVA 4EQEA 3SPDA 3I24A 3WO5A 3OJ7A 1KPAA 6FITA 1RZYA 4FITA 4NDFA 3O1CA 5IPBA 1AV5A 2Q4HA 4QDVA 3BL7A 1XMMA 3ANOA
chains in the Genus database with same CATH superfamily
5IPDA 1GUQA 1HXQA 3IMIA 1KPCA 1EMSA 1Z84A 3O0MA 3LB5A 4NJXA 3RHNA 4INIA 2Q4LA 4NDIA 1VLRA 5ED3A 5I2EA 1ST0A 3O1ZA 3NRDA 3SPLA 1ST4A 3BL9A 4G0AA 4XBAA 1L9VA 5IPCA 4I5WA 4RHNA 4NDGA 3O1XA 5IPEA 5I2FA 1XMLA 5BV3A 4ZGLA 5FITA 1HXPA 4NDHA 3FITA 2EO4A 4EGUA 1ZWJA 2H39A 3BLAA 2POFA 4EQGA 4QDEA 2OIKA 3OXKA 4INCA 3N1SA 2R7JA 3L7XA 5EMTA 5RHNA 1Y23A 2R7PA 4G0JA 4I5VA 4NK0A 4EQHA 2FITA 4NJZA 4NJYA 5CS2A 5ED6A 4YKLB 1FHIA 4QEBA 4ZKVA 3R6FA 3SP4A 3I4SA 3OMFA 3QGZA 1KPBA 3OHEA 3SZQA 2FHIA 1KPEA 3P0TA 2LJWA 1KPFA 2R8FA 5IN3A 3TW2A 2GU0A 4ZKLA 4I5TA 1GUPA 3N1TA 1FITA 6RHNA 2R7CA 3KSVA 4EQEA 3SPDA 3I24A 3WO5A 3OJ7A 1KPAA 6FITA 1RZYA 4FITA 4NDFA 3O1CA 5IPBA 1AV5A 2Q4HA 4QDVA 3BL7A 1XMMA 3ANOA
chains in the Genus database with same CATH topology
5IPDA 1GUQA 1HXQA 3IMIA 1KPCA 1EMSA 1Z84A 3O0MA 3LB5A 4NJXA 3RHNA 4INIA 2Q4LA 4NDIA 1VLRA 5ED3A 5I2EA 1ST0A 3O1ZA 3NRDA 3SPLA 1ST4A 3BL9A 4XBAA 5IPCA 4RHNA 4NDGA 3O1XA 5IPEA 5I2FA 1XMLA 5BV3A 4ZGLA 5FITA 1HXPA 4NDHA 3FITA 2EO4A 4EGUA 1ZWJA 2H39A 3BLAA 4EQGA 4QDEA 2OIKA 3OXKA 4INCA 3N1SA 3L7XA 5EMTA 5RHNA 1Y23A 4NK0A 4EQHA 2FITA 4NJZA 4NJYA 5CS2A 5ED6A 4YKLB 1FHIA 4QEBA 4ZKVA 3R6FA 3SP4A 3I4SA 3OMFA 3QGZA 1KPBA 3OHEA 3SZQA 2FHIA 1KPEA 3P0TA 1KPFA 5IN3A 3TW2A 4ZKLA 1GUPA 3N1TA 1FITA 6RHNA 3KSVA 4EQEA 3SPDA 3I24A 3WO5A 3OJ7A 1KPAA 6FITA 1RZYA 4FITA 4NDFA 3O1CA 5IPBA 1AV5A 2Q4HA 4QDVA 3BL7A 1XMMA 3ANOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IPD A;  1GUQ A;  1HXQ A;  3IMI A;  1KPC A;  1EMS A;  1Z84 A;  3O0M A;  3LB5 A;  4NJX A;  3RHN A;  4INI A;  2Q4L A;  4NDI A;  1VLR A;  5ED3 A;  5I2E A;  1ST0 A;  3O1Z A;  3NRD A;  3SPL A;  1ST4 A;  3BL9 A;  4XBA A;  5IPC A;  4RHN A;  4NDG A;  3O1X A;  5IPE A;  5I2F A;  1XML A;  5BV3 A;  4ZGL A;  5FIT A;  1HXP A;  4NDH A;  3FIT A;  2EO4 A;  4EGU A;  1ZWJ A;  2H39 A;  3BLA A;  4EQG A;  4QDE A;  2OIK A;  3OXK A;  4INC A;  3N1S A;  3L7X A;  5EMT A;  5RHN A;  1Y23 A;  4NK0 A;  4EQH A;  2FIT A;  4NJZ A;  4NJY A;  5CS2 A;  5ED6 A;  4YKL B;  1FHI A;  4QEB A;  4ZKV A;  3R6F A;  3SP4 A;  3I4S A;  3OMF A;  3QGZ A;  1KPB A;  3OHE A;  3SZQ A;  2FHI A;  1KPE A;  3P0T A;  1KPF A;  5IN3 A;  3TW2 A;  4ZKL A;  1GUP A;  3N1T A;  1FIT A;  6RHN A;  3KSV A;  4EQE A;  3SPD A;  3I24 A;  3WO5 A;  3OJ7 A;  1KPA A;  6FIT A;  1RZY A;  4FIT A;  4NDF A;  3O1C A;  5IPB A;  1AV5 A;  2Q4H A;  4QDV A;  3BL7 A;  1XMM A;  3ANO A; 
#chains in the Genus database with same CATH topology
 5IPD A;  1GUQ A;  1HXQ A;  3IMI A;  1KPC A;  1EMS A;  1Z84 A;  3O0M A;  3LB5 A;  4NJX A;  3RHN A;  4INI A;  2Q4L A;  4NDI A;  1VLR A;  5ED3 A;  5I2E A;  1ST0 A;  3O1Z A;  3NRD A;  3SPL A;  1ST4 A;  3BL9 A;  4G0A A;  4XBA A;  1L9V A;  5IPC A;  4I5W A;  4RHN A;  4NDG A;  3O1X A;  5IPE A;  5I2F A;  1XML A;  5BV3 A;  4ZGL A;  5FIT A;  1HXP A;  4NDH A;  3FIT A;  2EO4 A;  4EGU A;  1ZWJ A;  2H39 A;  3BLA A;  2POF A;  4EQG A;  4QDE A;  2OIK A;  3OXK A;  4INC A;  3N1S A;  2R7J A;  3L7X A;  5EMT A;  5RHN A;  1Y23 A;  2R7P A;  4G0J A;  4I5V A;  4NK0 A;  4EQH A;  2FIT A;  4NJZ A;  4NJY A;  5CS2 A;  5ED6 A;  4YKL B;  1FHI A;  4QEB A;  4ZKV A;  3R6F A;  3SP4 A;  3I4S A;  3OMF A;  3QGZ A;  1KPB A;  3OHE A;  3SZQ A;  2FHI A;  1KPE A;  3P0T A;  2LJW A;  1KPF A;  2R8F A;  5IN3 A;  3TW2 A;  2GU0 A;  4ZKL A;  4I5T A;  1GUP A;  3N1T A;  1FIT A;  6RHN A;  2R7C A;  3KSV A;  4EQE A;  3SPD A;  3I24 A;  3WO5 A;  3OJ7 A;  1KPA A;  6FIT A;  1RZY A;  4FIT A;  4NDF A;  3O1C A;  5IPB A;  1AV5 A;  2Q4H A;  4QDV A;  3BL7 A;  1XMM A;  3ANO A; 
#chains in the Genus database with same CATH homology
 5IPD A;  1GUQ A;  1HXQ A;  3IMI A;  1KPC A;  1EMS A;  1Z84 A;  3O0M A;  3LB5 A;  4NJX A;  3RHN A;  4INI A;  2Q4L A;  4NDI A;  1VLR A;  5ED3 A;  5I2E A;  1ST0 A;  3O1Z A;  3NRD A;  3SPL A;  1ST4 A;  3BL9 A;  4XBA A;  5IPC A;  4RHN A;  4NDG A;  3O1X A;  5IPE A;  5I2F A;  1XML A;  5BV3 A;  4ZGL A;  5FIT A;  1HXP A;  4NDH A;  3FIT A;  2EO4 A;  4EGU A;  1ZWJ A;  2H39 A;  3BLA A;  4EQG A;  4QDE A;  2OIK A;  3OXK A;  4INC A;  3N1S A;  3L7X A;  5EMT A;  5RHN A;  1Y23 A;  4NK0 A;  4EQH A;  2FIT A;  4NJZ A;  4NJY A;  5CS2 A;  5ED6 A;  4YKL B;  1FHI A;  4QEB A;  4ZKV A;  3R6F A;  3SP4 A;  3I4S A;  3OMF A;  3QGZ A;  1KPB A;  3OHE A;  3SZQ A;  2FHI A;  1KPE A;  3P0T A;  1KPF A;  5IN3 A;  3TW2 A;  4ZKL A;  1GUP A;  3N1T A;  1FIT A;  6RHN A;  3KSV A;  4EQE A;  3SPD A;  3I24 A;  3WO5 A;  3OJ7 A;  1KPA A;  6FIT A;  1RZY A;  4FIT A;  4NDF A;  3O1C A;  5IPB A;  1AV5 A;  2Q4H A;  4QDV A;  3BL7 A;  1XMM A;  3ANO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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