2R7CA

Crystallographic and biochemical analysis of rotavirus nsp2 with nucleotides reveals an ndp kinase like activity
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
312
structure length
307
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGYRIVKYSSVANHADRVYATFKSNVKNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
pubmed doi rcsb
molecule tags Rna binding protein
source organism Simian 11 rotavirus (serotype 3 / strain sa11-ramig)
molecule keywords Non-structural RNA-binding protein 35
total genus 88
structure length 307
sequence length 312
ec nomenclature
pdb deposition date 2007-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 2r7cA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 2r7cA01
2GU0A 2R7PA 2R7JA 1L9VA 2R7CA 2R8FA 4G0AA 4G0JA
chains in the Genus database with same CATH superfamily
4EGUA 1FITA 5CS2A 3N1SA 4INIA 4I5VA 3O1ZA 4EQEA 1ST4A 2POFA 3P0TA 4XBAA 3O1XA 2R7PA 2R8FA 1HXPA 3IMIA 1Y23A 1GUQA 3R6FA 5ED3A 1AV5A 5FITA 4NDFA 1FHIA 4RHNA 3OJ7A 1ZWJA 3FITA 5EMTA 2EO4A 6RHNA 5I2FA 3OXKA 5RHNA 2FITA 5IPCA 6FITA 3LB5A 3L7XA 4EQGA 3ANOA 2FHIA 1KPBA 3RHNA 4QDEA 1KPEA 1Z84A 4EQHA 3NRDA 4INCA 3BLAA 3OMFA 4FITA 1XMMA 4ZKVA 2R7CA 4NDHA 2OIKA 3TW2A 3SZQA 2LJWA 5BV3A 1RZYA 4G0JA 1HXQA 4ZGLA 3KSVA 3WO5A 3SPLA 1ST0A 4YKLB 3OHEA 3QGZA 3BL7A 3I4SA 5IPDA 1KPAA 5IPBA 1KPCA 1GUPA 3BL9A 1VLRA 2H39A 3I24A 5ED6A 3SP4A 2Q4LA 5I2EA 1EMSA 1L9VA 5IPEA 1XMLA 4NK0A 4I5TA 3O1CA 2GU0A 4NDIA 5IN3A 4NJZA 4ZKLA 2R7JA 4NJXA 4QEBA 4G0AA 1KPFA 4I5WA 3N1TA 2Q4HA 3O0MA 4NDGA 4NJYA 3SPDA 4QDVA
chains in the Genus database with same CATH topology
2GU0A 2R7PA 2R7JA 1L9VA 2R7CA 2R8FA 4G0AA 4G0JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GU0 A;  2R7P A;  2R7J A;  1L9V A;  2R7C A;  2R8F A;  4G0A A;  4G0J A; 
#chains in the Genus database with same CATH topology
 4EGU A;  1FIT A;  5CS2 A;  3N1S A;  4INI A;  4I5V A;  3O1Z A;  4EQE A;  1ST4 A;  2POF A;  3P0T A;  4XBA A;  3O1X A;  2R7P A;  2R8F A;  1HXP A;  3IMI A;  1Y23 A;  1GUQ A;  3R6F A;  5ED3 A;  1AV5 A;  5FIT A;  4NDF A;  1FHI A;  4RHN A;  3OJ7 A;  1ZWJ A;  3FIT A;  5EMT A;  2EO4 A;  6RHN A;  5I2F A;  3OXK A;  5RHN A;  2FIT A;  5IPC A;  6FIT A;  3LB5 A;  3L7X A;  4EQG A;  3ANO A;  2FHI A;  1KPB A;  3RHN A;  4QDE A;  1KPE A;  1Z84 A;  4EQH A;  3NRD A;  4INC A;  3BLA A;  3OMF A;  4FIT A;  1XMM A;  4ZKV A;  2R7C A;  4NDH A;  2OIK A;  3TW2 A;  3SZQ A;  2LJW A;  5BV3 A;  1RZY A;  4G0J A;  1HXQ A;  4ZGL A;  3KSV A;  3WO5 A;  3SPL A;  1ST0 A;  4YKL B;  3OHE A;  3QGZ A;  3BL7 A;  3I4S A;  5IPD A;  1KPA A;  5IPB A;  1KPC A;  1GUP A;  3BL9 A;  1VLR A;  2H39 A;  3I24 A;  5ED6 A;  3SP4 A;  2Q4L A;  5I2E A;  1EMS A;  1L9V A;  5IPE A;  1XML A;  4NK0 A;  4I5T A;  3O1C A;  2GU0 A;  4NDI A;  5IN3 A;  4NJZ A;  4ZKL A;  2R7J A;  4NJX A;  4QEB A;  4G0A A;  1KPF A;  4I5W A;  3N1T A;  2Q4H A;  3O0M A;  4NDG A;  4NJY A;  3SPD A;  4QDV A; 
#chains in the Genus database with same CATH homology
 2GU0 A;  2R7P A;  2R7J A;  1L9V A;  2R7C A;  2R8F A;  4G0A A;  4G0J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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