2WXTA

Clostridium perfringens alpha-toxin strain nctc8237
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
370
structure length
359
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDTLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFSDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 134
structure length 359
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxtA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxtA02
3BNEA 4JDGA 5FBGA 1F8NA 1NO3A 1OLPA 1FGTA 4QWTA 1P6DA 2HUCA 1BU8A 2PVSA 3V99A 2IUJA 3BNDA 3VF1A 1AH7A 3PZWA 4WFOA 3SNGA 2SBLA 3BNCA 3CWZB 5FBCA 4CXVA 2WY6A 1QM6A 1Y4KA 1ROVA 3BNBA 3V98A 3FG3A 1FGOA 4NREA 1KHOA 1N8SA 3W52A 4DJ4A 1N8QA 1LNHA 4CXOA 5FBFA 2FFZA 4WHAA 5FB9A 1LPAB 1P5XA 2PPLA 1W52X 2WXTA 1AK0A 1FGMA 1LPBB 5FBAA 3FG1A 1HPLA 1RRHA 3FG4A 4CWMA 1FGQA 1GYGA 5EEOA 2OXEA 1RP1A 1HU9A 1CA1A 1LOXA 5FBDA 4CXPA 1JNQA 1P6EA 2FNQA 2FGNA 1GPLA 2WXUA 2IUKA 1FGRA 5FBBA 2P0MA 1YGEA 1RRLA 1QMDA 3O8YA 1ETHA 3V92A 1IK3A
chains in the Genus database with same CATH superfamily
3BNEA 4JDGA 5FBGA 1F8NA 1NO3A 1OLPA 1FGTA 4QWTA 1P6DA 2HUCA 1BU8A 2PVSA 3V99A 2LRGA 2IUJA 3BNDA 2LGEA 3VF1A 2QNGA 1AH7A 3PZWA 4WFOA 3SNGA 2SBLA 3BNCA 5FBCA 3CWZB 4CXVA 2WY6A 1QM6A 1Y4KA 1ROVA 3BNBA 3V98A 3FG3A 1FGOA 4NREA 1KHOA 1N8SA 3W52A 4DJ4A 1N8QA 2KXVA 1LNHA 4CXOA 5FBFA 2FFZA 4WHAA 5FB9A 1LPAB 1P5XA 2XFEA 2PPLA 1W52X 3IBZA 2WXTA 1AK0A 1FGMA 1LPBB 5FBAA 3FG1A 1HPLA 1RRHA 3FG4A 4CWMA 1FGQA 1GYGA 5EEOA 2OXEA 1RP1A 1HU9A 1CA1A 1LOXA 5FBDA 4CXPA 3U6GA 2XHJA 1JNQA 1P6EA 2XFDA 2FNQA 2FGNA 1GPLA 2WXUA 2IUKA 1FGRA 2QZ7A 2LG7A 2KXTA 5FBBA 2P0MA 2XHHA 1YGEA 1RRLA 1QMDA 3O8YA 4QEYA 1ETHA 3V92A 1IK3A
chains in the Genus database with same CATH topology
3BNEA 4JDGA 5FBGA 1F8NA 1NO3A 1OLPA 1FGTA 4QWTA 1P6DA 2HUCA 1BU8A 2PVSA 3V99A 2IUJA 3BNDA 3VF1A 1AH7A 3PZWA 4WFOA 3SNGA 2SBLA 3BNCA 3CWZB 5FBCA 4CXVA 2WY6A 1QM6A 1Y4KA 1ROVA 3BNBA 3V98A 3FG3A 1FGOA 4NREA 1KHOA 1N8SA 3W52A 4DJ4A 1N8QA 1LNHA 4CXOA 5FBFA 2FFZA 4WHAA 5FB9A 1LPAB 1P5XA 2PPLA 1W52X 2WXTA 1AK0A 1FGMA 1LPBB 5FBAA 3FG1A 1HPLA 1RRHA 3FG4A 4CWMA 1FGQA 1GYGA 5EEOA 2OXEA 1RP1A 1HU9A 1CA1A 1LOXA 5FBDA 4CXPA 1JNQA 1P6EA 2FNQA 2FGNA 1GPLA 2WXUA 2IUKA 1FGRA 5FBBA 2P0MA 1YGEA 1RRLA 1QMDA 3O8YA 1ETHA 3V92A 1IK3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BNE A;  4JDG A;  5FBG A;  1F8N A;  1NO3 A;  1OLP A;  1FGT A;  4QWT A;  1P6D A;  2HUC A;  1BU8 A;  2PVS A;  3V99 A;  2IUJ A;  3BND A;  3VF1 A;  1AH7 A;  3PZW A;  4WFO A;  3SNG A;  2SBL A;  3BNC A;  3CWZ B;  5FBC A;  4CXV A;  2WY6 A;  1QM6 A;  1Y4K A;  1ROV A;  3BNB A;  3V98 A;  3FG3 A;  1FGO A;  4NRE A;  1KHO A;  1N8S A;  3W52 A;  4DJ4 A;  1N8Q A;  1LNH A;  4CXO A;  5FBF A;  2FFZ A;  4WHA A;  5FB9 A;  1LPA B;  1P5X A;  2PPL A;  1W52 X;  2WXT A;  1AK0 A;  1FGM A;  1LPB B;  5FBA A;  3FG1 A;  1HPL A;  1RRH A;  3FG4 A;  4CWM A;  1FGQ A;  1GYG A;  5EEO A;  2OXE A;  1RP1 A;  1HU9 A;  1CA1 A;  1LOX A;  5FBD A;  4CXP A;  1JNQ A;  1P6E A;  2FNQ A;  2FGN A;  1GPL A;  2WXU A;  2IUK A;  1FGR A;  5FBB A;  2P0M A;  1YGE A;  1RRL A;  1QMD A;  3O8Y A;  1ETH A;  3V92 A;  1IK3 A; 
#chains in the Genus database with same CATH topology
 3BNE A;  4JDG A;  5FBG A;  1F8N A;  1NO3 A;  1OLP A;  1FGT A;  4QWT A;  1P6D A;  2HUC A;  1BU8 A;  2PVS A;  3V99 A;  2LRG A;  2IUJ A;  3BND A;  2LGE A;  3VF1 A;  2QNG A;  1AH7 A;  3PZW A;  4WFO A;  3SNG A;  2SBL A;  3BNC A;  5FBC A;  3CWZ B;  4CXV A;  2WY6 A;  1QM6 A;  1Y4K A;  1ROV A;  3BNB A;  3V98 A;  3FG3 A;  1FGO A;  4NRE A;  1KHO A;  1N8S A;  3W52 A;  4DJ4 A;  1N8Q A;  2KXV A;  1LNH A;  4CXO A;  5FBF A;  2FFZ A;  4WHA A;  5FB9 A;  1LPA B;  1P5X A;  2XFE A;  2PPL A;  1W52 X;  3IBZ A;  2WXT A;  1AK0 A;  1FGM A;  1LPB B;  5FBA A;  3FG1 A;  1HPL A;  1RRH A;  3FG4 A;  4CWM A;  1FGQ A;  1GYG A;  5EEO A;  2OXE A;  1RP1 A;  1HU9 A;  1CA1 A;  1LOX A;  5FBD A;  4CXP A;  3U6G A;  2XHJ A;  1JNQ A;  1P6E A;  2XFD A;  2FNQ A;  2FGN A;  1GPL A;  2WXU A;  2IUK A;  1FGR A;  2QZ7 A;  2LG7 A;  2KXT A;  5FBB A;  2P0M A;  2XHH A;  1YGE A;  1RRL A;  1QMD A;  3O8Y A;  4QEY A;  1ETH A;  3V92 A;  1IK3 A; 
#chains in the Genus database with same CATH homology
 3BNE A;  4JDG A;  5FBG A;  1F8N A;  1NO3 A;  1OLP A;  1FGT A;  4QWT A;  1P6D A;  2HUC A;  1BU8 A;  2PVS A;  3V99 A;  2IUJ A;  3BND A;  3VF1 A;  1AH7 A;  3PZW A;  4WFO A;  3SNG A;  2SBL A;  3BNC A;  3CWZ B;  5FBC A;  4CXV A;  2WY6 A;  1QM6 A;  1Y4K A;  1ROV A;  3BNB A;  3V98 A;  3FG3 A;  1FGO A;  4NRE A;  1KHO A;  1N8S A;  3W52 A;  4DJ4 A;  1N8Q A;  1LNH A;  4CXO A;  5FBF A;  2FFZ A;  4WHA A;  5FB9 A;  1LPA B;  1P5X A;  2PPL A;  1W52 X;  2WXT A;  1AK0 A;  1FGM A;  1LPB B;  5FBA A;  3FG1 A;  1HPL A;  1RRH A;  3FG4 A;  4CWM A;  1FGQ A;  1GYG A;  5EEO A;  2OXE A;  1RP1 A;  1HU9 A;  1CA1 A;  1LOX A;  5FBD A;  4CXP A;  1JNQ A;  1P6E A;  2FNQ A;  2FGN A;  1GPL A;  2WXU A;  2IUK A;  1FGR A;  5FBB A;  2P0M A;  1YGE A;  1RRL A;  1QMD A;  3O8Y A;  1ETH A;  3V92 A;  1IK3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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