2WXUA

Clostridium perfringens alpha-toxin strain nctc8237 mutant t74i
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
370
structure length
361
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDIWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 139
structure length 361
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxuA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxuA02
3O8YA 1ROVA 4WFOA 3FG4A 1CA1A 2FFZA 1NO3A 1P6DA 3V92A 1P6EA 2PPLA 4CXOA 3FG1A 4NREA 3VF1A 1FGQA 2IUJA 2FNQA 3SNGA 2WXTA 3CWZB 1IK3A 1RRHA 3BNBA 1LOXA 1HU9A 1GYGA 1Y4KA 1FGMA 1LNHA 4DJ4A 5FBFA 1N8QA 2OXEA 1FGTA 1FGOA 1P5XA 4CXVA 1JNQA 1QM6A 2FGNA 5FBAA 5FBDA 1GPLA 3BNEA 5FBBA 1KHOA 1AK0A 1LPAB 5FB9A 1LPBB 1QMDA 1BU8A 3W52A 1ETHA 5FBCA 1OLPA 2P0MA 3BNDA 4WHAA 2WY6A 5EEOA 2WXUA 2HUCA 4JDGA 1F8NA 5FBGA 1RP1A 3BNCA 2IUKA 3V99A 1YGEA 1W52X 1HPLA 1N8SA 3FG3A 3PZWA 1RRLA 2PVSA 4CXPA 2SBLA 1FGRA 4CWMA 3V98A 4QWTA 1AH7A
chains in the Genus database with same CATH superfamily
3O8YA 1ROVA 2QNGA 2XHHA 4WFOA 3FG4A 1CA1A 2FFZA 1NO3A 1P6DA 2LRGA 2KXVA 3V92A 1P6EA 2PPLA 4CXOA 3FG1A 2LGEA 4NREA 3VF1A 1FGQA 3IBZA 2IUJA 2FNQA 3SNGA 2WXTA 3CWZB 1IK3A 1RRHA 3BNBA 1LOXA 1HU9A 1GYGA 1Y4KA 1FGMA 1LNHA 4QEYA 2QZ7A 2XFEA 2KXTA 4DJ4A 5FBFA 1N8QA 2OXEA 1FGTA 1FGOA 1P5XA 4CXVA 1JNQA 1QM6A 2FGNA 5FBAA 5FBDA 1GPLA 2XFDA 3BNEA 5FBBA 1KHOA 1AK0A 1LPAB 5FB9A 1LPBB 1QMDA 1BU8A 3W52A 1ETHA 2LG7A 5FBCA 1OLPA 2P0MA 3BNDA 4WHAA 2WY6A 5EEOA 2WXUA 2HUCA 3U6GA 4JDGA 1F8NA 5FBGA 1RP1A 3BNCA 2IUKA 3V99A 1YGEA 1W52X 1HPLA 1N8SA 3FG3A 3PZWA 1RRLA 2PVSA 4CXPA 2XHJA 2SBLA 1FGRA 4CWMA 3V98A 4QWTA 1AH7A
chains in the Genus database with same CATH topology
3O8YA 1ROVA 4WFOA 3FG4A 1CA1A 2FFZA 1NO3A 1P6DA 3V92A 1P6EA 2PPLA 4CXOA 3FG1A 4NREA 3VF1A 1FGQA 2IUJA 2FNQA 3SNGA 2WXTA 3CWZB 1IK3A 1RRHA 3BNBA 1LOXA 1HU9A 1GYGA 1Y4KA 1FGMA 1LNHA 4DJ4A 5FBFA 1N8QA 2OXEA 1FGTA 1FGOA 1P5XA 4CXVA 1JNQA 1QM6A 2FGNA 5FBAA 5FBDA 1GPLA 3BNEA 5FBBA 1KHOA 1AK0A 1LPAB 5FB9A 1LPBB 1QMDA 1BU8A 3W52A 1ETHA 5FBCA 1OLPA 2P0MA 3BNDA 4WHAA 2WY6A 5EEOA 2WXUA 2HUCA 4JDGA 1F8NA 5FBGA 1RP1A 3BNCA 2IUKA 3V99A 1YGEA 1W52X 1HPLA 1N8SA 3FG3A 3PZWA 1RRLA 2PVSA 4CXPA 2SBLA 1FGRA 4CWMA 3V98A 4QWTA 1AH7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O8Y A;  1ROV A;  4WFO A;  3FG4 A;  1CA1 A;  2FFZ A;  1NO3 A;  1P6D A;  3V92 A;  1P6E A;  2PPL A;  4CXO A;  3FG1 A;  4NRE A;  3VF1 A;  1FGQ A;  2IUJ A;  2FNQ A;  3SNG A;  2WXT A;  3CWZ B;  1IK3 A;  1RRH A;  3BNB A;  1LOX A;  1HU9 A;  1GYG A;  1Y4K A;  1FGM A;  1LNH A;  4DJ4 A;  5FBF A;  1N8Q A;  2OXE A;  1FGT A;  1FGO A;  1P5X A;  4CXV A;  1JNQ A;  1QM6 A;  2FGN A;  5FBA A;  5FBD A;  1GPL A;  3BNE A;  5FBB A;  1KHO A;  1AK0 A;  1LPA B;  5FB9 A;  1LPB B;  1QMD A;  1BU8 A;  3W52 A;  1ETH A;  5FBC A;  1OLP A;  2P0M A;  3BND A;  4WHA A;  2WY6 A;  5EEO A;  2WXU A;  2HUC A;  4JDG A;  1F8N A;  5FBG A;  1RP1 A;  3BNC A;  2IUK A;  3V99 A;  1YGE A;  1W52 X;  1HPL A;  1N8S A;  3FG3 A;  3PZW A;  1RRL A;  2PVS A;  4CXP A;  2SBL A;  1FGR A;  4CWM A;  3V98 A;  4QWT A;  1AH7 A; 
#chains in the Genus database with same CATH topology
 3O8Y A;  1ROV A;  2QNG A;  2XHH A;  4WFO A;  3FG4 A;  1CA1 A;  2FFZ A;  1NO3 A;  1P6D A;  2LRG A;  2KXV A;  3V92 A;  1P6E A;  2PPL A;  4CXO A;  3FG1 A;  2LGE A;  4NRE A;  3VF1 A;  1FGQ A;  3IBZ A;  2IUJ A;  2FNQ A;  3SNG A;  2WXT A;  3CWZ B;  1IK3 A;  1RRH A;  3BNB A;  1LOX A;  1HU9 A;  1GYG A;  1Y4K A;  1FGM A;  1LNH A;  4QEY A;  2QZ7 A;  2XFE A;  2KXT A;  4DJ4 A;  5FBF A;  1N8Q A;  2OXE A;  1FGT A;  1FGO A;  1P5X A;  4CXV A;  1JNQ A;  1QM6 A;  2FGN A;  5FBA A;  5FBD A;  1GPL A;  2XFD A;  3BNE A;  5FBB A;  1KHO A;  1AK0 A;  1LPA B;  5FB9 A;  1LPB B;  1QMD A;  1BU8 A;  3W52 A;  1ETH A;  2LG7 A;  5FBC A;  1OLP A;  2P0M A;  3BND A;  4WHA A;  2WY6 A;  5EEO A;  2WXU A;  2HUC A;  3U6G A;  4JDG A;  1F8N A;  5FBG A;  1RP1 A;  3BNC A;  2IUK A;  3V99 A;  1YGE A;  1W52 X;  1HPL A;  1N8S A;  3FG3 A;  3PZW A;  1RRL A;  2PVS A;  4CXP A;  2XHJ A;  2SBL A;  1FGR A;  4CWM A;  3V98 A;  4QWT A;  1AH7 A; 
#chains in the Genus database with same CATH homology
 3O8Y A;  1ROV A;  4WFO A;  3FG4 A;  1CA1 A;  2FFZ A;  1NO3 A;  1P6D A;  3V92 A;  1P6E A;  2PPL A;  4CXO A;  3FG1 A;  4NRE A;  3VF1 A;  1FGQ A;  2IUJ A;  2FNQ A;  3SNG A;  2WXT A;  3CWZ B;  1IK3 A;  1RRH A;  3BNB A;  1LOX A;  1HU9 A;  1GYG A;  1Y4K A;  1FGM A;  1LNH A;  4DJ4 A;  5FBF A;  1N8Q A;  2OXE A;  1FGT A;  1FGO A;  1P5X A;  4CXV A;  1JNQ A;  1QM6 A;  2FGN A;  5FBA A;  5FBD A;  1GPL A;  3BNE A;  5FBB A;  1KHO A;  1AK0 A;  1LPA B;  5FB9 A;  1LPB B;  1QMD A;  1BU8 A;  3W52 A;  1ETH A;  5FBC A;  1OLP A;  2P0M A;  3BND A;  4WHA A;  2WY6 A;  5EEO A;  2WXU A;  2HUC A;  4JDG A;  1F8N A;  5FBG A;  1RP1 A;  3BNC A;  2IUK A;  3V99 A;  1YGE A;  1W52 X;  1HPL A;  1N8S A;  3FG3 A;  3PZW A;  1RRL A;  2PVS A;  4CXP A;  2SBL A;  1FGR A;  4CWM A;  3V98 A;  4QWT A;  1AH7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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