2WXUA

Clostridium perfringens alpha-toxin strain nctc8237 mutant t74i
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
370
structure length
361
Chain Sequence
WDGKIDGTGTHAMIVTQGVSILENDLSKNEPESVRKNLEILKENMHELQLGSTYPDYDKNAYDLYQDHFWDPDIWYLAYSIPDTGESQIRKFSALARYEWQRGNYKQATFYLGEAMHYFGDIDTPYHPANVTAVDSAGHVKFETFAEERKEQYKINTAGCKTNEAFYTDILKNKDFNAWSKEYARGFAKTGKSIYYSHASMSHSWDDWDYAAKVTLANSQKGTAGYIYRFLHDVSEGNDPSVGKNVKELVAYISTSGEKDAGTDDYMYFGIKTKDGKTQEWEMDNPGNDFMTGSKDTYTFKLKDENLKIDDIQNMWIRKRKYTAFPDAYKPENIKIIANGKVVVDKDINEWISGNSTYNIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
pubmed doi rcsb
molecule tags Hydrolase
source organism Clostridium perfringens
molecule keywords PHOSPHOLIPASE C
total genus 139
structure length 361
sequence length 370
ec nomenclature ec 3.1.4.3: Phospholipase C.
pdb deposition date 2009-11-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00882 Zn_dep_PLPC Zinc dependent phospholipase C
A PF01477 PLAT PLAT/LH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.575.10 Mainly Alpha Orthogonal Bundle P1 Nuclease P1 Nuclease 2wxuA01
2.60.60.20 Mainly Beta Sandwich Lipoxygenase-1 PLAT/LH2 domain 2wxuA02
1P6EA 5FB9A 5FBGA 1LNHA 1GPLA 1IK3A 3O8YA 1HPLA 5FBDA 1CA1A 1LPBB 4NREA 5FBCA 3VF1A 4JDGA 2FGNA 2WXUA 1RRLA 1FGRA 2WXTA 5FBBA 2IUKA 1GYGA 1AH7A 1QMDA 1LOXA 3CWZB 2PPLA 1QM6A 4CWMA 2OXEA 3FG1A 3V98A 2P0MA 2FNQA 1RRHA 1P6DA 5FBFA 2PVSA 3BNBA 1KHOA 1BU8A 2IUJA 4QWTA 2SBLA 1LPAB 1N8SA 1N8QA 1JNQA 1OLPA 3V92A 2WY6A 4WHAA 2FFZA 1ROVA 3W52A 3BNCA 1ETHA 1FGTA 4WFOA 4CXVA 3V99A 1P5XA 4DJ4A 1YGEA 1NO3A 2HUCA 1F8NA 3PZWA 3FG4A 1Y4KA 1RP1A 1FGOA 1FGQA 5EEOA 1W52X 3SNGA 4CXOA 3BNDA 3FG3A 5FBAA 3BNEA 4CXPA 1AK0A 1FGMA 1HU9A
chains in the Genus database with same CATH superfamily
1P6EA 5FB9A 5FBGA 1LNHA 1GPLA 1IK3A 3O8YA 1HPLA 5FBDA 2QNGA 1CA1A 1LPBB 4NREA 5FBCA 3VF1A 4JDGA 2FGNA 2WXUA 1RRLA 1FGRA 2WXTA 5FBBA 2IUKA 1GYGA 1AH7A 1QMDA 1LOXA 3CWZB 2PPLA 1QM6A 4CWMA 2OXEA 3FG1A 3V98A 2P0MA 2FNQA 1RRHA 1P6DA 5FBFA 2PVSA 3BNBA 1KHOA 1BU8A 4QEYA 2IUJA 2KXTA 4QWTA 3U6GA 2SBLA 2QZ7A 2XHJA 1LPAB 1N8SA 1N8QA 2XFEA 1JNQA 3IBZA 1OLPA 3V92A 2WY6A 4WHAA 2FFZA 1ROVA 3W52A 2LG7A 2LGEA 1ETHA 3BNCA 1FGTA 2XFDA 2KXVA 4WFOA 4CXVA 3V99A 1P5XA 4DJ4A 1YGEA 1NO3A 2HUCA 2XHHA 1F8NA 3PZWA 3FG4A 1Y4KA 1RP1A 1FGOA 1FGQA 5EEOA 1W52X 3SNGA 4CXOA 3BNDA 3FG3A 5FBAA 3BNEA 2LRGA 4CXPA 1AK0A 1FGMA 1HU9A
chains in the Genus database with same CATH topology
1P6EA 5FB9A 5FBGA 1LNHA 1GPLA 1IK3A 3O8YA 1HPLA 5FBDA 1CA1A 1LPBB 4NREA 5FBCA 3VF1A 4JDGA 2FGNA 2WXUA 1RRLA 1FGRA 2WXTA 5FBBA 2IUKA 1GYGA 1AH7A 1QMDA 1LOXA 3CWZB 2PPLA 1QM6A 4CWMA 2OXEA 3FG1A 3V98A 2P0MA 2FNQA 1RRHA 1P6DA 5FBFA 2PVSA 3BNBA 1KHOA 1BU8A 2IUJA 4QWTA 2SBLA 1LPAB 1N8SA 1N8QA 1JNQA 1OLPA 3V92A 2WY6A 4WHAA 2FFZA 1ROVA 3W52A 3BNCA 1ETHA 1FGTA 4WFOA 4CXVA 3V99A 1P5XA 4DJ4A 1YGEA 1NO3A 2HUCA 1F8NA 3PZWA 3FG4A 1Y4KA 1RP1A 1FGOA 1FGQA 5EEOA 1W52X 3SNGA 4CXOA 3BNDA 3FG3A 5FBAA 3BNEA 4CXPA 1AK0A 1FGMA 1HU9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P6E A;  5FB9 A;  5FBG A;  1LNH A;  1GPL A;  1IK3 A;  3O8Y A;  1HPL A;  5FBD A;  1CA1 A;  1LPB B;  4NRE A;  5FBC A;  3VF1 A;  4JDG A;  2FGN A;  2WXU A;  1RRL A;  1FGR A;  2WXT A;  5FBB A;  2IUK A;  1GYG A;  1AH7 A;  1QMD A;  1LOX A;  3CWZ B;  2PPL A;  1QM6 A;  4CWM A;  2OXE A;  3FG1 A;  3V98 A;  2P0M A;  2FNQ A;  1RRH A;  1P6D A;  5FBF A;  2PVS A;  3BNB A;  1KHO A;  1BU8 A;  2IUJ A;  4QWT A;  2SBL A;  1LPA B;  1N8S A;  1N8Q A;  1JNQ A;  1OLP A;  3V92 A;  2WY6 A;  4WHA A;  2FFZ A;  1ROV A;  3W52 A;  3BNC A;  1ETH A;  1FGT A;  4WFO A;  4CXV A;  3V99 A;  1P5X A;  4DJ4 A;  1YGE A;  1NO3 A;  2HUC A;  1F8N A;  3PZW A;  3FG4 A;  1Y4K A;  1RP1 A;  1FGO A;  1FGQ A;  5EEO A;  1W52 X;  3SNG A;  4CXO A;  3BND A;  3FG3 A;  5FBA A;  3BNE A;  4CXP A;  1AK0 A;  1FGM A;  1HU9 A; 
#chains in the Genus database with same CATH topology
 1P6E A;  5FB9 A;  5FBG A;  1LNH A;  1GPL A;  1IK3 A;  3O8Y A;  1HPL A;  5FBD A;  2QNG A;  1CA1 A;  1LPB B;  4NRE A;  5FBC A;  3VF1 A;  4JDG A;  2FGN A;  2WXU A;  1RRL A;  1FGR A;  2WXT A;  5FBB A;  2IUK A;  1GYG A;  1AH7 A;  1QMD A;  1LOX A;  3CWZ B;  2PPL A;  1QM6 A;  4CWM A;  2OXE A;  3FG1 A;  3V98 A;  2P0M A;  2FNQ A;  1RRH A;  1P6D A;  5FBF A;  2PVS A;  3BNB A;  1KHO A;  1BU8 A;  4QEY A;  2IUJ A;  2KXT A;  4QWT A;  3U6G A;  2SBL A;  2QZ7 A;  2XHJ A;  1LPA B;  1N8S A;  1N8Q A;  2XFE A;  1JNQ A;  3IBZ A;  1OLP A;  3V92 A;  2WY6 A;  4WHA A;  2FFZ A;  1ROV A;  3W52 A;  2LG7 A;  2LGE A;  1ETH A;  3BNC A;  1FGT A;  2XFD A;  2KXV A;  4WFO A;  4CXV A;  3V99 A;  1P5X A;  4DJ4 A;  1YGE A;  1NO3 A;  2HUC A;  2XHH A;  1F8N A;  3PZW A;  3FG4 A;  1Y4K A;  1RP1 A;  1FGO A;  1FGQ A;  5EEO A;  1W52 X;  3SNG A;  4CXO A;  3BND A;  3FG3 A;  5FBA A;  3BNE A;  2LRG A;  4CXP A;  1AK0 A;  1FGM A;  1HU9 A; 
#chains in the Genus database with same CATH homology
 1P6E A;  5FB9 A;  5FBG A;  1LNH A;  1GPL A;  1IK3 A;  3O8Y A;  1HPL A;  5FBD A;  1CA1 A;  1LPB B;  4NRE A;  5FBC A;  3VF1 A;  4JDG A;  2FGN A;  2WXU A;  1RRL A;  1FGR A;  2WXT A;  5FBB A;  2IUK A;  1GYG A;  1AH7 A;  1QMD A;  1LOX A;  3CWZ B;  2PPL A;  1QM6 A;  4CWM A;  2OXE A;  3FG1 A;  3V98 A;  2P0M A;  2FNQ A;  1RRH A;  1P6D A;  5FBF A;  2PVS A;  3BNB A;  1KHO A;  1BU8 A;  2IUJ A;  4QWT A;  2SBL A;  1LPA B;  1N8S A;  1N8Q A;  1JNQ A;  1OLP A;  3V92 A;  2WY6 A;  4WHA A;  2FFZ A;  1ROV A;  3W52 A;  3BNC A;  1ETH A;  1FGT A;  4WFO A;  4CXV A;  3V99 A;  1P5X A;  4DJ4 A;  1YGE A;  1NO3 A;  2HUC A;  1F8N A;  3PZW A;  3FG4 A;  1Y4K A;  1RP1 A;  1FGO A;  1FGQ A;  5EEO A;  1W52 X;  3SNG A;  4CXO A;  3BND A;  3FG3 A;  5FBA A;  3BNE A;  4CXP A;  1AK0 A;  1FGM A;  1HU9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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