2ZMXB

Crystal structure of the met1-form of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking in cupric sulfate solution for 36 hours
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
83
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHYDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis
pubmed doi rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 17
structure length 77
sequence length 83
ec nomenclature
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zmxB01
2ZMYB 3AWWB 2ZWFB 1WX2B 3AWZB 2JV8A 2ZMXB 3AWVB 3AWYB 3AX0B 1WX4B 2ZWDB 2AHKB 2ZWEB 2ZWGB 2AHLB 2ZMZB 3AWTB 1WXCB 1WX5B 3AWXB 3AWUB 3AWSB
chains in the Genus database with same CATH superfamily
2DE5A 4NBGA 2ZMYB 3AWWB 4NBDA 2ZWFB 1WX2B 3AWZB 2JV8A 2ZMXB 3GKQA 1WW9A 4NBHA 3AWVB 3AWYB 1Z03A 1WX4B 3AX0B 4NBBA 1Z01A 2ZWDB 2AHKB 2ZWEB 2ZWGB 2AHLB 3GCFA 4NBFA 3VMGA 1Z02A 2DE6A 2ZMZB 4NB8A 2DE7A 4NBEA 3AWTB 3VMIA 4NBAA 3VMHA 1WXCB 1WX5B 4NBCA 3AWXB 4NB9A 3AWUB 3AWSB
chains in the Genus database with same CATH topology
2ZMYB 3AWWB 2ZWFB 1WX2B 3AWZB 2JV8A 2ZMXB 3AWVB 3AWYB 3AX0B 1WX4B 2ZWDB 2AHKB 2ZWEB 2ZWGB 2AHLB 2ZMZB 3AWTB 1WXCB 1WX5B 3AWXB 3AWUB 3AWSB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZMY B;  3AWW B;  2ZWF B;  1WX2 B;  3AWZ B;  2JV8 A;  2ZMX B;  3AWV B;  3AWY B;  3AX0 B;  1WX4 B;  2ZWD B;  2AHK B;  2ZWE B;  2ZWG B;  2AHL B;  2ZMZ B;  3AWT B;  1WXC B;  1WX5 B;  3AWX B;  3AWU B;  3AWS B; 
#chains in the Genus database with same CATH topology
 2DE5 A;  4NBG A;  2ZMY B;  3AWW B;  4NBD A;  2ZWF B;  1WX2 B;  3AWZ B;  2JV8 A;  2ZMX B;  3GKQ A;  1WW9 A;  4NBH A;  3AWV B;  3AWY B;  1Z03 A;  1WX4 B;  3AX0 B;  4NBB A;  1Z01 A;  2ZWD B;  2AHK B;  2ZWE B;  2ZWG B;  2AHL B;  3GCF A;  4NBF A;  3VMG A;  1Z02 A;  2DE6 A;  2ZMZ B;  4NB8 A;  2DE7 A;  4NBE A;  3AWT B;  3VMI A;  4NBA A;  3VMH A;  1WXC B;  1WX5 B;  4NBC A;  3AWX B;  4NB9 A;  3AWU B;  3AWS B; 
#chains in the Genus database with same CATH homology
 2ZMY B;  3AWW B;  2ZWF B;  1WX2 B;  3AWZ B;  2JV8 A;  2ZMX B;  3AWV B;  3AWY B;  3AX0 B;  1WX4 B;  2ZWD B;  2AHK B;  2ZWE B;  2ZWG B;  2AHL B;  2ZMZ B;  3AWT B;  1WXC B;  1WX5 B;  3AWX B;  3AWU B;  3AWS B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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