2ZMXB

Crystal structure of the met1-form of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking in cupric sulfate solution for 36 hours
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
83
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHYDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase/metal transport
molecule keywords Tyrosinase
publication title Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis
pubmed doi rcsb
source organism Streptomyces castaneoglobisporus
total genus 17
structure length 77
sequence length 83
ec nomenclature
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zmxB01
2ZWFB 2ZMXB 3AWYB 2ZMZB 3AWXB 3AWWB 2ZWDB 2JV8A 2ZWEB 2ZWGB 3AWSB 2AHLB 2ZMYB 1WX4B 3AWTB 1WX2B 1WX5B 3AWVB 3AWUB 2AHKB 3AWZB 1WXCB 3AX0B
chains in the Genus database with same CATH superfamily
1Z03A 3GKQA 2ZWFB 4NBDA 4NBHA 1Z01A 2ZMXB 3AWYB 2DE7A 2ZMZB 3AWXB 4NBAA 3AWWB 3VMHA 2ZWDB 4NB8A 2JV8A 2ZWEB 3VMGA 4NBGA 3GCFA 2ZWGB 1WW9A 3AWSB 4NBFA 2AHLB 2DE5A 2ZMYB 4NB9A 4NBBA 1WX4B 4NBEA 3AWTB 1WX2B 1WX5B 1Z02A 3AWVB 3AWUB 2AHKB 2DE6A 3AWZB 4NBCA 3VMIA 1WXCB 3AX0B
chains in the Genus database with same CATH topology
2ZWFB 2ZMXB 3AWYB 2ZMZB 3AWXB 3AWWB 2ZWDB 2JV8A 2ZWEB 2ZWGB 3AWSB 2AHLB 2ZMYB 1WX4B 3AWTB 1WX2B 1WX5B 3AWVB 3AWUB 2AHKB 3AWZB 1WXCB 3AX0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZWF B;  2ZMX B;  3AWY B;  2ZMZ B;  3AWX B;  3AWW B;  2ZWD B;  2JV8 A;  2ZWE B;  2ZWG B;  3AWS B;  2AHL B;  2ZMY B;  1WX4 B;  3AWT B;  1WX2 B;  1WX5 B;  3AWV B;  3AWU B;  2AHK B;  3AWZ B;  1WXC B;  3AX0 B; 
#chains in the Genus database with same CATH topology
 1Z03 A;  3GKQ A;  2ZWF B;  4NBD A;  4NBH A;  1Z01 A;  2ZMX B;  3AWY B;  2DE7 A;  2ZMZ B;  3AWX B;  4NBA A;  3AWW B;  3VMH A;  2ZWD B;  4NB8 A;  2JV8 A;  2ZWE B;  3VMG A;  4NBG A;  3GCF A;  2ZWG B;  1WW9 A;  3AWS B;  4NBF A;  2AHL B;  2DE5 A;  2ZMY B;  4NB9 A;  4NBB A;  1WX4 B;  4NBE A;  3AWT B;  1WX2 B;  1WX5 B;  1Z02 A;  3AWV B;  3AWU B;  2AHK B;  2DE6 A;  3AWZ B;  4NBC A;  3VMI A;  1WXC B;  3AX0 B; 
#chains in the Genus database with same CATH homology
 2ZWF B;  2ZMX B;  3AWY B;  2ZMZ B;  3AWX B;  3AWW B;  2ZWD B;  2JV8 A;  2ZWE B;  2ZWG B;  3AWS B;  2AHL B;  2ZMY B;  1WX4 B;  3AWT B;  1WX2 B;  1WX5 B;  3AWV B;  3AWU B;  2AHK B;  3AWZ B;  1WXC B;  3AX0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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