2ZWDB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 5 minutes
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
84
structure length
73
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHYDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 15
structure length 73
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwdB01
2AHLB 1WX2B 2ZMXB 3AWUB 3AWYB 2JV8A 2ZWEB 1WX5B 2ZWGB 3AWTB 2AHKB 2ZWDB 3AWXB 3AWZB 3AWVB 2ZMZB 3AWWB 3AX0B 1WXCB 1WX4B 3AWSB 2ZMYB 2ZWFB
chains in the Genus database with same CATH superfamily
3VMIA 1WW9A 2AHLB 3GKQA 1WX2B 3VMGA 2ZMXB 3AWUB 2DE6A 2DE5A 4NBBA 1Z01A 3AWYB 4NBFA 2JV8A 2ZWEB 1WX5B 4NB8A 2ZWGB 3AWTB 4NBCA 2AHKB 4NBDA 2ZWDB 3AWXB 3VMHA 1Z02A 4NBHA 3AWZB 2DE7A 3AWVB 2ZMZB 4NBEA 3AWWB 3AX0B 4NB9A 4NBGA 1WXCB 1WX4B 4NBAA 3AWSB 1Z03A 2ZMYB 2ZWFB 3GCFA
chains in the Genus database with same CATH topology
2AHLB 1WX2B 2ZMXB 3AWUB 3AWYB 2JV8A 2ZWEB 1WX5B 2ZWGB 3AWTB 2AHKB 2ZWDB 3AWXB 3AWZB 3AWVB 2ZMZB 3AWWB 3AX0B 1WXCB 1WX4B 3AWSB 2ZMYB 2ZWFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AHL B;  1WX2 B;  2ZMX B;  3AWU B;  3AWY B;  2JV8 A;  2ZWE B;  1WX5 B;  2ZWG B;  3AWT B;  2AHK B;  2ZWD B;  3AWX B;  3AWZ B;  3AWV B;  2ZMZ B;  3AWW B;  3AX0 B;  1WXC B;  1WX4 B;  3AWS B;  2ZMY B;  2ZWF B; 
#chains in the Genus database with same CATH topology
 3VMI A;  1WW9 A;  2AHL B;  3GKQ A;  1WX2 B;  3VMG A;  2ZMX B;  3AWU B;  2DE6 A;  2DE5 A;  4NBB A;  1Z01 A;  3AWY B;  4NBF A;  2JV8 A;  2ZWE B;  1WX5 B;  4NB8 A;  2ZWG B;  3AWT B;  4NBC A;  2AHK B;  4NBD A;  2ZWD B;  3AWX B;  3VMH A;  1Z02 A;  4NBH A;  3AWZ B;  2DE7 A;  3AWV B;  2ZMZ B;  4NBE A;  3AWW B;  3AX0 B;  4NB9 A;  4NBG A;  1WXC B;  1WX4 B;  4NBA A;  3AWS B;  1Z03 A;  2ZMY B;  2ZWF B;  3GCF A; 
#chains in the Genus database with same CATH homology
 2AHL B;  1WX2 B;  2ZMX B;  3AWU B;  3AWY B;  2JV8 A;  2ZWE B;  1WX5 B;  2ZWG B;  3AWT B;  2AHK B;  2ZWD B;  3AWX B;  3AWZ B;  3AWV B;  2ZMZ B;  3AWW B;  3AX0 B;  1WXC B;  1WX4 B;  3AWS B;  2ZMY B;  2ZWF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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