2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
3AWTB 3AWXB 2ZMYB 2AHKB 1WX5B 2ZWDB 2AHLB 2ZMZB 3AWWB 2ZWGB 3AWYB 1WXCB 3AWUB 3AX0B 2JV8A 2ZWFB 3AWVB 2ZWEB 1WX2B 3AWSB 1WX4B 3AWZB 2ZMXB
chains in the Genus database with same CATH superfamily
3AWTB 3AWXB 2ZMYB 1Z01A 1Z03A 4NBFA 3GCFA 1WW9A 2AHKB 3VMIA 4NBAA 3VMGA 3VMHA 2DE6A 4NBGA 1WX5B 2DE7A 2ZWDB 2AHLB 4NBHA 4NBEA 2ZMZB 3AWWB 2ZWGB 3GKQA 3AWYB 1WXCB 4NB8A 2DE5A 4NBBA 3AWUB 3AX0B 2JV8A 2ZWFB 3AWVB 2ZWEB 4NBCA 1WX2B 4NB9A 3AWSB 1Z02A 1WX4B 3AWZB 4NBDA 2ZMXB
chains in the Genus database with same CATH topology
3AWTB 3AWXB 2ZMYB 2AHKB 1WX5B 2ZWDB 2AHLB 2ZMZB 3AWWB 2ZWGB 3AWYB 1WXCB 3AWUB 3AX0B 2JV8A 2ZWFB 3AWVB 2ZWEB 1WX2B 3AWSB 1WX4B 3AWZB 2ZMXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWT B;  3AWX B;  2ZMY B;  2AHK B;  1WX5 B;  2ZWD B;  2AHL B;  2ZMZ B;  3AWW B;  2ZWG B;  3AWY B;  1WXC B;  3AWU B;  3AX0 B;  2JV8 A;  2ZWF B;  3AWV B;  2ZWE B;  1WX2 B;  3AWS B;  1WX4 B;  3AWZ B;  2ZMX B; 
#chains in the Genus database with same CATH topology
 3AWT B;  3AWX B;  2ZMY B;  1Z01 A;  1Z03 A;  4NBF A;  3GCF A;  1WW9 A;  2AHK B;  3VMI A;  4NBA A;  3VMG A;  3VMH A;  2DE6 A;  4NBG A;  1WX5 B;  2DE7 A;  2ZWD B;  2AHL B;  4NBH A;  4NBE A;  2ZMZ B;  3AWW B;  2ZWG B;  3GKQ A;  3AWY B;  1WXC B;  4NB8 A;  2DE5 A;  4NBB A;  3AWU B;  3AX0 B;  2JV8 A;  2ZWF B;  3AWV B;  2ZWE B;  4NBC A;  1WX2 B;  4NB9 A;  3AWS B;  1Z02 A;  1WX4 B;  3AWZ B;  4NBD A;  2ZMX B; 
#chains in the Genus database with same CATH homology
 3AWT B;  3AWX B;  2ZMY B;  2AHK B;  1WX5 B;  2ZWD B;  2AHL B;  2ZMZ B;  3AWW B;  2ZWG B;  3AWY B;  1WXC B;  3AWU B;  3AX0 B;  2JV8 A;  2ZWF B;  3AWV B;  2ZWE B;  1WX2 B;  3AWS B;  1WX4 B;  3AWZ B;  2ZMX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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