2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
molecule keywords Tyrosinase
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
3AX0B 2ZWFB 3AWYB 2AHKB 2JV8A 3AWZB 3AWXB 3AWWB 2ZMZB 2ZWEB 2AHLB 2ZWDB 3AWSB 2ZWGB 1WX5B 3AWVB 2ZMYB 1WXCB 3AWTB 1WX4B 1WX2B 3AWUB 2ZMXB
chains in the Genus database with same CATH superfamily
3AX0B 2DE5A 2ZWFB 2DE6A 2AHKB 3AWYB 2JV8A 3GCFA 1Z02A 3AWZB 3AWXB 3AWWB 4NBCA 4NBHA 2ZMZB 2ZWEB 2DE7A 4NBFA 3VMHA 4NBGA 1Z01A 2AHLB 2ZWDB 3VMIA 3AWSB 2ZWGB 1Z03A 1WX5B 3AWVB 2ZMYB 3GKQA 1WXCB 4NBEA 3VMGA 4NBAA 3AWTB 1WW9A 1WX4B 1WX2B 4NB8A 3AWUB 4NBBA 4NBDA 4NB9A 2ZMXB
chains in the Genus database with same CATH topology
3AX0B 2ZWFB 3AWYB 2AHKB 2JV8A 3AWZB 3AWXB 3AWWB 2ZMZB 2ZWEB 2AHLB 2ZWDB 3AWSB 2ZWGB 1WX5B 3AWVB 2ZMYB 1WXCB 3AWTB 1WX4B 1WX2B 3AWUB 2ZMXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AX0 B;  2ZWF B;  3AWY B;  2AHK B;  2JV8 A;  3AWZ B;  3AWX B;  3AWW B;  2ZMZ B;  2ZWE B;  2AHL B;  2ZWD B;  3AWS B;  2ZWG B;  1WX5 B;  3AWV B;  2ZMY B;  1WXC B;  3AWT B;  1WX4 B;  1WX2 B;  3AWU B;  2ZMX B; 
#chains in the Genus database with same CATH topology
 3AX0 B;  2DE5 A;  2ZWF B;  2DE6 A;  2AHK B;  3AWY B;  2JV8 A;  3GCF A;  1Z02 A;  3AWZ B;  3AWX B;  3AWW B;  4NBC A;  4NBH A;  2ZMZ B;  2ZWE B;  2DE7 A;  4NBF A;  3VMH A;  4NBG A;  1Z01 A;  2AHL B;  2ZWD B;  3VMI A;  3AWS B;  2ZWG B;  1Z03 A;  1WX5 B;  3AWV B;  2ZMY B;  3GKQ A;  1WXC B;  4NBE A;  3VMG A;  4NBA A;  3AWT B;  1WW9 A;  1WX4 B;  1WX2 B;  4NB8 A;  3AWU B;  4NBB A;  4NBD A;  4NB9 A;  2ZMX B; 
#chains in the Genus database with same CATH homology
 3AX0 B;  2ZWF B;  3AWY B;  2AHK B;  2JV8 A;  3AWZ B;  3AWX B;  3AWW B;  2ZMZ B;  2ZWE B;  2AHL B;  2ZWD B;  3AWS B;  2ZWG B;  1WX5 B;  3AWV B;  2ZMY B;  1WXC B;  3AWT B;  1WX4 B;  1WX2 B;  3AWU B;  2ZMX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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