2ZWEB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 40 minutes
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
84
structure length
77
Chain Sequence
AAPESFDEVYKGRRIQGRPAHEHGGGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLPF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 77
sequence length 84
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zweB01
3AWWB 3AWZB 2ZWDB 2ZMYB 2JV8A 3AX0B 2ZWFB 3AWTB 2ZMZB 2AHLB 2ZWGB 3AWYB 2ZWEB 1WX2B 3AWVB 1WXCB 1WX4B 2AHKB 1WX5B 3AWSB 2ZMXB 3AWXB 3AWUB
chains in the Genus database with same CATH superfamily
4NBAA 3AWWB 3AWZB 4NBFA 2ZWDB 2ZMYB 2DE7A 2JV8A 1Z02A 3AX0B 2ZWFB 3AWTB 3VMGA 2ZMZB 3GCFA 4NB9A 2AHLB 2ZWGB 3AWXB 2DE6A 3AWYB 4NBHA 3VMHA 1WW9A 2DE5A 3VMIA 4NBEA 2ZWEB 1WX2B 4NB8A 3AWVB 1Z01A 1WXCB 4NBBA 1WX4B 2AHKB 3GKQA 4NBCA 4NBGA 4NBDA 1WX5B 3AWSB 2ZMXB 1Z03A 3AWUB
chains in the Genus database with same CATH topology
3AWWB 3AWZB 2ZWDB 2ZMYB 2JV8A 3AX0B 2ZWFB 3AWTB 2ZMZB 2AHLB 2ZWGB 3AWYB 2ZWEB 1WX2B 3AWVB 1WXCB 1WX4B 2AHKB 1WX5B 3AWSB 2ZMXB 3AWXB 3AWUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWW B;  3AWZ B;  2ZWD B;  2ZMY B;  2JV8 A;  3AX0 B;  2ZWF B;  3AWT B;  2ZMZ B;  2AHL B;  2ZWG B;  3AWY B;  2ZWE B;  1WX2 B;  3AWV B;  1WXC B;  1WX4 B;  2AHK B;  1WX5 B;  3AWS B;  2ZMX B;  3AWX B;  3AWU B; 
#chains in the Genus database with same CATH topology
 4NBA A;  3AWW B;  3AWZ B;  4NBF A;  2ZWD B;  2ZMY B;  2DE7 A;  2JV8 A;  1Z02 A;  3AX0 B;  2ZWF B;  3AWT B;  3VMG A;  2ZMZ B;  3GCF A;  4NB9 A;  2AHL B;  2ZWG B;  3AWX B;  2DE6 A;  3AWY B;  4NBH A;  3VMH A;  1WW9 A;  2DE5 A;  3VMI A;  4NBE A;  2ZWE B;  1WX2 B;  4NB8 A;  3AWV B;  1Z01 A;  1WXC B;  4NBB A;  1WX4 B;  2AHK B;  3GKQ A;  4NBC A;  4NBG A;  4NBD A;  1WX5 B;  3AWS B;  2ZMX B;  1Z03 A;  3AWU B; 
#chains in the Genus database with same CATH homology
 3AWW B;  3AWZ B;  2ZWD B;  2ZMY B;  2JV8 A;  3AX0 B;  2ZWF B;  3AWT B;  2ZMZ B;  2AHL B;  2ZWG B;  3AWY B;  2ZWE B;  1WX2 B;  3AWV B;  1WXC B;  1WX4 B;  2AHK B;  1WX5 B;  3AWS B;  2ZMX B;  3AWX B;  3AWU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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