2ZWFB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 15
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwfB01
2ZWFB 2AHLB 1WX5B 2ZWEB 3AWYB 3AWSB 1WX2B 3AWZB 3AWXB 2ZWDB 3AX0B 3AWWB 2ZMYB 2AHKB 2ZMXB 2JV8A 2ZMZB 3AWUB 1WXCB 3AWVB 3AWTB 1WX4B 2ZWGB
chains in the Genus database with same CATH superfamily
3GKQA 2ZWFB 1Z01A 2AHLB 1WW9A 2DE7A 1Z02A 4NBEA 1WX5B 2ZWEB 3AWYB 4NBFA 3VMIA 3AWSB 4NBBA 4NB9A 4NBGA 1Z03A 1WX2B 3AWZB 3AWXB 2ZWDB 3AX0B 3VMGA 3VMHA 3AWWB 3GCFA 2DE5A 2ZMYB 2AHKB 4NBDA 2ZMXB 4NBAA 2JV8A 2ZMZB 3AWUB 1WXCB 4NB8A 3AWVB 3AWTB 4NBCA 4NBHA 1WX4B 2DE6A 2ZWGB
chains in the Genus database with same CATH topology
2ZWFB 2AHLB 1WX5B 2ZWEB 3AWYB 3AWSB 1WX2B 3AWZB 3AWXB 2ZWDB 3AX0B 3AWWB 2ZMYB 2AHKB 2ZMXB 2JV8A 2ZMZB 3AWUB 1WXCB 3AWVB 3AWTB 1WX4B 2ZWGB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZWF B;  2AHL B;  1WX5 B;  2ZWE B;  3AWY B;  3AWS B;  1WX2 B;  3AWZ B;  3AWX B;  2ZWD B;  3AX0 B;  3AWW B;  2ZMY B;  2AHK B;  2ZMX B;  2JV8 A;  2ZMZ B;  3AWU B;  1WXC B;  3AWV B;  3AWT B;  1WX4 B;  2ZWG B; 
#chains in the Genus database with same CATH topology
 3GKQ A;  2ZWF B;  1Z01 A;  2AHL B;  1WW9 A;  2DE7 A;  1Z02 A;  4NBE A;  1WX5 B;  2ZWE B;  3AWY B;  4NBF A;  3VMI A;  3AWS B;  4NBB A;  4NB9 A;  4NBG A;  1Z03 A;  1WX2 B;  3AWZ B;  3AWX B;  2ZWD B;  3AX0 B;  3VMG A;  3VMH A;  3AWW B;  3GCF A;  2DE5 A;  2ZMY B;  2AHK B;  4NBD A;  2ZMX B;  4NBA A;  2JV8 A;  2ZMZ B;  3AWU B;  1WXC B;  4NB8 A;  3AWV B;  3AWT B;  4NBC A;  4NBH A;  1WX4 B;  2DE6 A;  2ZWG B; 
#chains in the Genus database with same CATH homology
 2ZWF B;  2AHL B;  1WX5 B;  2ZWE B;  3AWY B;  3AWS B;  1WX2 B;  3AWZ B;  3AWX B;  2ZWD B;  3AX0 B;  3AWW B;  2ZMY B;  2AHK B;  2ZMX B;  2JV8 A;  2ZMZ B;  3AWU B;  1WXC B;  3AWV B;  3AWT B;  1WX4 B;  2ZWG B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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