2ZWFB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 15
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwfB01
3AWWB 1WXCB 3AX0B 2ZWEB 2ZMXB 3AWTB 3AWZB 3AWUB 2AHLB 1WX5B 2ZMZB 2ZWGB 2ZMYB 2ZWDB 2ZWFB 1WX2B 3AWVB 3AWYB 2AHKB 3AWXB 1WX4B 3AWSB 2JV8A
chains in the Genus database with same CATH superfamily
4NBCA 3AWWB 1WXCB 4NBFA 2DE6A 2DE7A 4NBGA 4NB9A 3AX0B 3GCFA 2ZWEB 2DE5A 1Z01A 2ZMXB 3VMHA 3AWTB 3AWZB 1Z03A 3AWUB 2AHLB 1WX5B 4NBHA 1WW9A 1Z02A 2ZMZB 2ZWGB 3GKQA 2ZMYB 2ZWDB 4NBAA 4NBEA 3VMGA 2ZWFB 1WX2B 3AWVB 3AWYB 2AHKB 3AWXB 1WX4B 3VMIA 3AWSB 2JV8A 4NB8A 4NBDA 4NBBA
chains in the Genus database with same CATH topology
3AWWB 1WXCB 3AX0B 2ZWEB 2ZMXB 3AWTB 3AWZB 3AWUB 2AHLB 1WX5B 2ZMZB 2ZWGB 2ZMYB 2ZWDB 2ZWFB 1WX2B 3AWVB 3AWYB 2AHKB 3AWXB 1WX4B 3AWSB 2JV8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWW B;  1WXC B;  3AX0 B;  2ZWE B;  2ZMX B;  3AWT B;  3AWZ B;  3AWU B;  2AHL B;  1WX5 B;  2ZMZ B;  2ZWG B;  2ZMY B;  2ZWD B;  2ZWF B;  1WX2 B;  3AWV B;  3AWY B;  2AHK B;  3AWX B;  1WX4 B;  3AWS B;  2JV8 A; 
#chains in the Genus database with same CATH topology
 4NBC A;  3AWW B;  1WXC B;  4NBF A;  2DE6 A;  2DE7 A;  4NBG A;  4NB9 A;  3AX0 B;  3GCF A;  2ZWE B;  2DE5 A;  1Z01 A;  2ZMX B;  3VMH A;  3AWT B;  3AWZ B;  1Z03 A;  3AWU B;  2AHL B;  1WX5 B;  4NBH A;  1WW9 A;  1Z02 A;  2ZMZ B;  2ZWG B;  3GKQ A;  2ZMY B;  2ZWD B;  4NBA A;  4NBE A;  3VMG A;  2ZWF B;  1WX2 B;  3AWV B;  3AWY B;  2AHK B;  3AWX B;  1WX4 B;  3VMI A;  3AWS B;  2JV8 A;  4NB8 A;  4NBD A;  4NBB A; 
#chains in the Genus database with same CATH homology
 3AWW B;  1WXC B;  3AX0 B;  2ZWE B;  2ZMX B;  3AWT B;  3AWZ B;  3AWU B;  2AHL B;  1WX5 B;  2ZMZ B;  2ZWG B;  2ZMY B;  2ZWD B;  2ZWF B;  1WX2 B;  3AWV B;  3AWY B;  2AHK B;  3AWX B;  1WX4 B;  3AWS B;  2JV8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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