2ZWGB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 12 hours
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwgB01
2ZWGB 2ZWEB 3AWTB 2AHKB 3AWUB 2AHLB 3AWXB 1WX5B 1WXCB 2ZWDB 2ZMXB 3AWYB 2ZWFB 3AWWB 3AWZB 1WX4B 3AWSB 3AWVB 2ZMYB 1WX2B 2JV8A 2ZMZB 3AX0B
chains in the Genus database with same CATH superfamily
2ZWGB 3GCFA 4NBEA 2ZWEB 3AWTB 4NBDA 2AHKB 3AWUB 3GKQA 3AWXB 1WX5B 2DE6A 2ZMZB 4NBHA 3VMGA 2DE7A 4NBFA 1WXCB 3VMIA 2DE5A 2ZWDB 2ZMXB 1Z03A 3AWYB 2ZWFB 3AWWB 3AWZB 1Z01A 4NB9A 1WX4B 4NBBA 3AWSB 4NBGA 1Z02A 4NBAA 3AWVB 1WW9A 2ZMYB 1WX2B 2JV8A 4NB8A 3VMHA 4NBCA 2AHLB 3AX0B
chains in the Genus database with same CATH topology
2ZWGB 2ZWEB 3AWTB 2AHKB 3AWUB 2AHLB 3AWXB 1WX5B 1WXCB 2ZWDB 2ZMXB 3AWYB 2ZWFB 3AWWB 3AWZB 1WX4B 3AWSB 3AWVB 2ZMYB 1WX2B 2JV8A 2ZMZB 3AX0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZWG B;  2ZWE B;  3AWT B;  2AHK B;  3AWU B;  2AHL B;  3AWX B;  1WX5 B;  1WXC B;  2ZWD B;  2ZMX B;  3AWY B;  2ZWF B;  3AWW B;  3AWZ B;  1WX4 B;  3AWS B;  3AWV B;  2ZMY B;  1WX2 B;  2JV8 A;  2ZMZ B;  3AX0 B; 
#chains in the Genus database with same CATH topology
 2ZWG B;  3GCF A;  4NBE A;  2ZWE B;  3AWT B;  4NBD A;  2AHK B;  3AWU B;  3GKQ A;  3AWX B;  1WX5 B;  2DE6 A;  2ZMZ B;  4NBH A;  3VMG A;  2DE7 A;  4NBF A;  1WXC B;  3VMI A;  2DE5 A;  2ZWD B;  2ZMX B;  1Z03 A;  3AWY B;  2ZWF B;  3AWW B;  3AWZ B;  1Z01 A;  4NB9 A;  1WX4 B;  4NBB A;  3AWS B;  4NBG A;  1Z02 A;  4NBA A;  3AWV B;  1WW9 A;  2ZMY B;  1WX2 B;  2JV8 A;  4NB8 A;  3VMH A;  4NBC A;  2AHL B;  3AX0 B; 
#chains in the Genus database with same CATH homology
 2ZWG B;  2ZWE B;  3AWT B;  2AHK B;  3AWU B;  2AHL B;  3AWX B;  1WX5 B;  1WXC B;  2ZWD B;  2ZMX B;  3AWY B;  2ZWF B;  3AWW B;  3AWZ B;  1WX4 B;  3AWS B;  3AWV B;  2ZMY B;  1WX2 B;  2JV8 A;  2ZMZ B;  3AX0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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