2ZWGB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 12 hours
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwgB01
2JV8A 1WX5B 2AHLB 1WX4B 1WX2B 2ZWEB 2ZMYB 3AWZB 3AX0B 2ZMXB 2AHKB 3AWSB 3AWUB 2ZWFB 3AWVB 3AWXB 1WXCB 3AWTB 2ZMZB 3AWYB 2ZWDB 2ZWGB 3AWWB
chains in the Genus database with same CATH superfamily
1Z01A 4NBAA 3VMHA 4NBFA 2JV8A 4NBEA 1WX5B 2AHLB 2DE7A 1Z02A 1WX4B 4NBHA 1WX2B 2ZWEB 2DE5A 2ZMYB 3VMIA 3GCFA 3AWZB 3AX0B 2ZMXB 2AHKB 3AWSB 3AWUB 4NB9A 2ZWFB 4NBBA 4NBCA 3AWVB 4NB8A 3GKQA 3AWXB 4NBGA 4NBDA 1WW9A 1WXCB 3VMGA 3AWTB 2ZMZB 3AWYB 2DE6A 2ZWDB 2ZWGB 3AWWB 1Z03A
chains in the Genus database with same CATH topology
2JV8A 1WX5B 2AHLB 1WX4B 1WX2B 2ZWEB 2ZMYB 3AWZB 3AX0B 2ZMXB 2AHKB 3AWSB 3AWUB 2ZWFB 3AWVB 3AWXB 1WXCB 3AWTB 2ZMZB 3AWYB 2ZWDB 2ZWGB 3AWWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JV8 A;  1WX5 B;  2AHL B;  1WX4 B;  1WX2 B;  2ZWE B;  2ZMY B;  3AWZ B;  3AX0 B;  2ZMX B;  2AHK B;  3AWS B;  3AWU B;  2ZWF B;  3AWV B;  3AWX B;  1WXC B;  3AWT B;  2ZMZ B;  3AWY B;  2ZWD B;  2ZWG B;  3AWW B; 
#chains in the Genus database with same CATH topology
 1Z01 A;  4NBA A;  3VMH A;  4NBF A;  2JV8 A;  4NBE A;  1WX5 B;  2AHL B;  2DE7 A;  1Z02 A;  1WX4 B;  4NBH A;  1WX2 B;  2ZWE B;  2DE5 A;  2ZMY B;  3VMI A;  3GCF A;  3AWZ B;  3AX0 B;  2ZMX B;  2AHK B;  3AWS B;  3AWU B;  4NB9 A;  2ZWF B;  4NBB A;  4NBC A;  3AWV B;  4NB8 A;  3GKQ A;  3AWX B;  4NBG A;  4NBD A;  1WW9 A;  1WXC B;  3VMG A;  3AWT B;  2ZMZ B;  3AWY B;  2DE6 A;  2ZWD B;  2ZWG B;  3AWW B;  1Z03 A; 
#chains in the Genus database with same CATH homology
 2JV8 A;  1WX5 B;  2AHL B;  1WX4 B;  1WX2 B;  2ZWE B;  2ZMY B;  3AWZ B;  3AX0 B;  2ZMX B;  2AHK B;  3AWS B;  3AWU B;  2ZWF B;  3AWV B;  3AWX B;  1WXC B;  3AWT B;  2ZMZ B;  3AWY B;  2ZWD B;  2ZWG B;  3AWW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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