2ZWGB

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 12 hours
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
83
structure length
71
Chain Sequence
AAPESFDEVYKGRRIQGRPAGYEVFVDGVQLHVMRNADGSWISVVSHDPVPTPRAAARAAVDELQGAPLLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase
rcsb
molecule keywords Tyrosinase
molecule tags Oxidoreductase/metal transport
source organism Streptomyces castaneoglobisporus
total genus 16
structure length 71
sequence length 83
ec nomenclature
pdb deposition date 2008-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF06236 MelC1 Tyrosinase co-factor MelC1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1880.10 Alpha Beta 2-Layer Sandwich protein ne1242 fold protein ne1242 domain like 2zwgB01
3AWYB 2ZMXB 3AWVB 3AWSB 1WXCB 2ZWFB 3AX0B 3AWXB 1WX5B 3AWTB 3AWZB 2AHKB 2ZWGB 1WX2B 2ZMZB 2JV8A 2AHLB 1WX4B 3AWUB 2ZMYB 3AWWB 2ZWEB 2ZWDB
chains in the Genus database with same CATH superfamily
4NBFA 3AWYB 2ZMXB 3AWVB 3AWSB 2DE7A 4NBDA 3VMGA 1WXCB 2ZWFB 1Z03A 4NBCA 4NBHA 3AX0B 4NB9A 3VMIA 3VMHA 1Z02A 3AWXB 1WX5B 3AWTB 3AWZB 4NBAA 2AHKB 2ZWGB 4NBBA 1WX2B 1Z01A 2JV8A 2ZMZB 3GKQA 2AHLB 1WX4B 3AWUB 3GCFA 4NB8A 2DE6A 4NBGA 2ZMYB 3AWWB 2ZWEB 4NBEA 2ZWDB 1WW9A 2DE5A
chains in the Genus database with same CATH topology
3AWYB 2ZMXB 3AWVB 3AWSB 1WXCB 2ZWFB 3AX0B 3AWXB 1WX5B 3AWTB 3AWZB 2AHKB 2ZWGB 1WX2B 2ZMZB 2JV8A 2AHLB 1WX4B 3AWUB 2ZMYB 3AWWB 2ZWEB 2ZWDB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3AWY B;  2ZMX B;  3AWV B;  3AWS B;  1WXC B;  2ZWF B;  3AX0 B;  3AWX B;  1WX5 B;  3AWT B;  3AWZ B;  2AHK B;  2ZWG B;  1WX2 B;  2ZMZ B;  2JV8 A;  2AHL B;  1WX4 B;  3AWU B;  2ZMY B;  3AWW B;  2ZWE B;  2ZWD B; 
#chains in the Genus database with same CATH topology
 4NBF A;  3AWY B;  2ZMX B;  3AWV B;  3AWS B;  2DE7 A;  4NBD A;  3VMG A;  1WXC B;  2ZWF B;  1Z03 A;  4NBC A;  4NBH A;  3AX0 B;  4NB9 A;  3VMI A;  3VMH A;  1Z02 A;  3AWX B;  1WX5 B;  3AWT B;  3AWZ B;  4NBA A;  2AHK B;  2ZWG B;  4NBB A;  1WX2 B;  1Z01 A;  2JV8 A;  2ZMZ B;  3GKQ A;  2AHL B;  1WX4 B;  3AWU B;  3GCF A;  4NB8 A;  2DE6 A;  4NBG A;  2ZMY B;  3AWW B;  2ZWE B;  4NBE A;  2ZWD B;  1WW9 A;  2DE5 A; 
#chains in the Genus database with same CATH homology
 3AWY B;  2ZMX B;  3AWV B;  3AWS B;  1WXC B;  2ZWF B;  3AX0 B;  3AWX B;  1WX5 B;  3AWT B;  3AWZ B;  2AHK B;  2ZWG B;  1WX2 B;  2ZMZ B;  2JV8 A;  2AHL B;  1WX4 B;  3AWU B;  2ZMY B;  3AWW B;  2ZWE B;  2ZWD B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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