3MI8D

The structure of tl1a-dcr3 complex
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
118
structure length
109
Chain Sequence
TPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCGTPSQNTQC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Decoy Strategies: The Structure of TL1A:DcR3 Complex.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15, SECRETED
total genus 13
structure length 109
sequence length 118
ec nomenclature
pdb deposition date 2010-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3mi8D01
3.10.360.30 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 3mi8D02
1EXTA 2HEYR 4YN0A 4J6GC 1SG1X 3MBWA 4M4RA 4I9XC 3U3PA 3U3SA 4KGQC 4BK4A 5BNQR 1ZA3R 4GIQR 5L36B 3MHDD 2UWIA 3FL7A 4E4DR 2H9GR 1D4VA 3ME4A 2HEVR 3QBQB 1FT4A 3K51B 5DMJA 3MI8D 3WVTA 1DU3A 4MXWR 4M4PA 4MSVB 4OD2S 4KGGC 2AW2B 1JMAB 3QO4A 2X10A 3BUKC 3IJ2X 3TJEF 5CIRE 3URFZ 1D0GR 4RSUD 3U3VA 4BK5A 3U3TA 3QD6R 3THMF 1NCFA 1TNRR 3ALQR 5IHLA 3U3QA 4N90R 4FHQA 3ME2R 3X3FA
chains in the Genus database with same CATH superfamily
1EXTA 2HEYR 4YN0A 4J6GC 1SG1X 3MBWA 4M4RA 4I9XC 3U3PA 3U3SA 1KJ6A 4KGQC 4BK4A 1FQQA 5BNQR 1ZA3R 4GIQR 5L36B 3MHDD 2UWIA 3FL7A 2QR6A 2E4UA 4E4DR 2H9GR 1D4VA 3ME4A 2HEVR 3QBQB 1FT4A 3K51B 5DMJA 3MI8D 3WVTA 2LWLA 1DU3A 4MXWR 4M4PA 4MSVB 4OD2S 4KGGC 2AW2B 1JMAB 2E4YA 3QO4A 1FD3A 2X10A 3BUKC 3IJ2X 3TJEF 2LXOA 5CIRE 1FD4A 3URFZ 2E4XA 4N90R 1D0GR 4RSUD 3U3VA 4BK5A 3U3TA 3QD6R 2MJKA 3THMF 1NCFA 1TNRR 3ALQR 3ME2R 5IHLA 3U3QA 2E4VA 4FHQA 2E4WA 3X3FA
chains in the Genus database with same CATH topology
1EXTA 2HEYR 4YN0A 4J6GC 1SG1X 3MBWA 4M4RA 4I9XC 3U3PA 3U3SA 1KJ6A 4KGQC 4BK4A 1FQQA 5BNQR 1ZA3R 4GIQR 5L36B 3MHDD 2UWIA 3FL7A 4E4DR 2H9GR 1D4VA 3ME4A 2HEVR 3QBQB 1FT4A 3K51B 5DMJA 3MI8D 3WVTA 2LWLA 1DU3A 4MXWR 4M4PA 4MSVB 4OD2S 4KGGC 2AW2B 1JMAB 1FD3A 3QO4A 2X10A 3BUKC 3IJ2X 3TJEF 2LXOA 5CIRE 1FD4A 3URFZ 1D0GR 4RSUD 3U3VA 4BK5A 3U3TA 3QD6R 2MJKA 3THMF 1NCFA 1TNRR 3ALQR 5IHLA 3U3QA 4N90R 4FHQA 3ME2R 3X3FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EXT A;  2HEY R;  4YN0 A;  4J6G C;  1SG1 X;  3MBW A;  4M4R A;  4I9X C;  3U3P A;  3U3S A;  4KGQ C;  4BK4 A;  5BNQ R;  1ZA3 R;  4GIQ R;  5L36 B;  3MHD D;  2UWI A;  3FL7 A;  4E4D R;  2H9G R;  1D4V A;  3ME4 A;  2HEV R;  3QBQ B;  1FT4 A;  3K51 B;  5DMJ A;  3MI8 D;  3WVT A;  1DU3 A;  4MXW R;  4M4P A;  4MSV B;  4OD2 S;  4KGG C;  2AW2 B;  1JMA B;  3QO4 A;  2X10 A;  3BUK C;  3IJ2 X;  3TJE F;  5CIR E;  3URF Z;  1D0G R;  4RSU D;  3U3V A;  4BK5 A;  3U3T A;  3QD6 R;  3THM F;  1NCF A;  1TNR R;  3ALQ R;  5IHL A;  3U3Q A;  4N90 R;  4FHQ A;  3ME2 R;  3X3F A; 
#chains in the Genus database with same CATH topology
 1EXT A;  2HEY R;  4YN0 A;  4J6G C;  1SG1 X;  3MBW A;  4M4R A;  4I9X C;  3U3P A;  3U3S A;  1KJ6 A;  4KGQ C;  4BK4 A;  1FQQ A;  5BNQ R;  1ZA3 R;  4GIQ R;  5L36 B;  3MHD D;  2UWI A;  3FL7 A;  2QR6 A;  2E4U A;  4E4D R;  2H9G R;  1D4V A;  3ME4 A;  2HEV R;  3QBQ B;  1FT4 A;  3K51 B;  5DMJ A;  3MI8 D;  3WVT A;  2LWL A;  1DU3 A;  4MXW R;  4M4P A;  4MSV B;  4OD2 S;  4KGG C;  2AW2 B;  1JMA B;  2E4Y A;  3QO4 A;  1FD3 A;  2X10 A;  3BUK C;  3IJ2 X;  3TJE F;  2LXO A;  5CIR E;  1FD4 A;  3URF Z;  2E4X A;  4N90 R;  1D0G R;  4RSU D;  3U3V A;  4BK5 A;  3U3T A;  3QD6 R;  2MJK A;  3THM F;  1NCF A;  1TNR R;  3ALQ R;  3ME2 R;  5IHL A;  3U3Q A;  2E4V A;  4FHQ A;  2E4W A;  3X3F A; 
#chains in the Genus database with same CATH homology
 1EXT A;  2HEY R;  4YN0 A;  4J6G C;  1SG1 X;  3MBW A;  4M4R A;  4I9X C;  3U3P A;  3U3S A;  1KJ6 A;  4KGQ C;  4BK4 A;  1FQQ A;  5BNQ R;  1ZA3 R;  4GIQ R;  5L36 B;  3MHD D;  2UWI A;  3FL7 A;  4E4D R;  2H9G R;  1D4V A;  3ME4 A;  2HEV R;  3QBQ B;  1FT4 A;  3K51 B;  5DMJ A;  3MI8 D;  3WVT A;  2LWL A;  1DU3 A;  4MXW R;  4M4P A;  4MSV B;  4OD2 S;  4KGG C;  2AW2 B;  1JMA B;  1FD3 A;  3QO4 A;  2X10 A;  3BUK C;  3IJ2 X;  3TJE F;  2LXO A;  5CIR E;  1FD4 A;  3URF Z;  1D0G R;  4RSU D;  3U3V A;  4BK5 A;  3U3T A;  3QD6 R;  2MJK A;  3THM F;  1NCF A;  1TNR R;  3ALQ R;  5IHL A;  3U3Q A;  4N90 R;  4FHQ A;  3ME2 R;  3X3F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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