3O0MA

Crystal structure of a zn-bound histidine triad family protein from mycobacterium smegmatis
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
145
structure length
139
Chain Sequence
GSMSCVFCAIVSGDAPAIRIYEDENFLGILDIRPFTRGHTLVIPKTHTVDLTDTPPETVAGMAAVGQRIARAARESGLHADGNNIAINDGKAAFQTVFHIHLHVVPRRNGDKLSFRRDPDREESGRLLRAALAQLDSAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium smegmatis str. mc2 155
molecule keywords HIT family protein
total genus 44
structure length 139
sequence length 145
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o0mA00
1ZWJA 1KPEA 2Q4LA 1KPBA 5IPEA 3O1XA 3BLAA 1GUQA 1VLRA 3SP4A 3N1SA 1RZYA 3RHNA 4NDIA 1XMLA 6RHNA 4ZKLA 5IPBA 5ED6A 3IMIA 3O1CA 1EMSA 1HXPA 4NDGA 3OXKA 3KSVA 4QEBA 3LB5A 4NJZA 3BL7A 3OHEA 1AV5A 1GUPA 3I4SA 4QDVA 3N1TA 3SZQA 1KPAA 1FHIA 3P0TA 5FITA 4EQEA 6FITA 1KPFA 4NK0A 4FITA 1HXQA 1KPCA 1ST0A 4EQGA 5ED3A 4NDFA 3NRDA 2OIKA 4RHNA 4INCA 5RHNA 5IPDA 4YKLB 2Q4HA 3OJ7A 4ZGLA 5CS2A 1FITA 3O1ZA 2EO4A 4NJYA 2FITA 3SPDA 2H39A 3SPLA 4NDHA 3QGZA 1Y23A 4QDEA 3I24A 4XBAA 1Z84A 3FITA 3R6FA 5I2EA 3BL9A 3WO5A 3OMFA 3TW2A 5IN3A 4NJXA 5EMTA 1XMMA 4INIA 4EGUA 4ZKVA 5BV3A 4EQHA 3L7XA 1ST4A 3ANOA 5IPCA 2FHIA 3O0MA 5I2FA
chains in the Genus database with same CATH superfamily
1ZWJA 1KPEA 2Q4LA 1KPBA 2LJWA 5IPEA 3O1XA 3BLAA 1GUQA 1VLRA 3SP4A 3N1SA 1RZYA 3RHNA 4NDIA 1XMLA 4I5WA 6RHNA 4ZKLA 5IPBA 5ED6A 3IMIA 3O1CA 1EMSA 1HXPA 4NDGA 3OXKA 3KSVA 4QEBA 3LB5A 2GU0A 4NJZA 3BL7A 3OHEA 1AV5A 1GUPA 3I4SA 4QDVA 3N1TA 3SZQA 1KPAA 1FHIA 3P0TA 5FITA 4EQEA 6FITA 1KPFA 4NK0A 4FITA 1HXQA 2POFA 2R7PA 1KPCA 1ST0A 4EQGA 4G0AA 5ED3A 4NDFA 3NRDA 2OIKA 4RHNA 4INCA 5RHNA 5IPDA 4YKLB 4I5TA 2Q4HA 3OJ7A 4ZGLA 5CS2A 1FITA 1L9VA 3O1ZA 2EO4A 4NJYA 2FITA 3SPDA 2H39A 3SPLA 4NDHA 3QGZA 1Y23A 4QDEA 3I24A 4XBAA 1Z84A 3FITA 2R8FA 3R6FA 5I2EA 3BL9A 3WO5A 3OMFA 3TW2A 5IN3A 4NJXA 5EMTA 1XMMA 4INIA 4EGUA 4ZKVA 4G0JA 4I5VA 5BV3A 2R7JA 4EQHA 3L7XA 2R7CA 1ST4A 3ANOA 5IPCA 2FHIA 3O0MA 5I2FA
chains in the Genus database with same CATH topology
1ZWJA 1KPEA 2Q4LA 1KPBA 5IPEA 3O1XA 3BLAA 1GUQA 1VLRA 3SP4A 3N1SA 1RZYA 3RHNA 4NDIA 1XMLA 6RHNA 4ZKLA 5IPBA 5ED6A 3IMIA 3O1CA 1EMSA 1HXPA 4NDGA 3OXKA 3KSVA 4QEBA 3LB5A 4NJZA 3BL7A 3OHEA 1AV5A 1GUPA 3I4SA 4QDVA 3N1TA 3SZQA 1KPAA 1FHIA 3P0TA 5FITA 4EQEA 6FITA 1KPFA 4NK0A 4FITA 1HXQA 1KPCA 1ST0A 4EQGA 5ED3A 4NDFA 3NRDA 2OIKA 4RHNA 4INCA 5RHNA 5IPDA 4YKLB 2Q4HA 3OJ7A 4ZGLA 5CS2A 1FITA 3O1ZA 2EO4A 4NJYA 2FITA 3SPDA 2H39A 3SPLA 4NDHA 3QGZA 1Y23A 4QDEA 3I24A 4XBAA 1Z84A 3FITA 3R6FA 5I2EA 3BL9A 3WO5A 3OMFA 3TW2A 5IN3A 4NJXA 5EMTA 1XMMA 4INIA 4EGUA 4ZKVA 5BV3A 4EQHA 3L7XA 1ST4A 3ANOA 5IPCA 2FHIA 3O0MA 5I2FA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZWJ A;  1KPE A;  2Q4L A;  1KPB A;  5IPE A;  3O1X A;  3BLA A;  1GUQ A;  1VLR A;  3SP4 A;  3N1S A;  1RZY A;  3RHN A;  4NDI A;  1XML A;  6RHN A;  4ZKL A;  5IPB A;  5ED6 A;  3IMI A;  3O1C A;  1EMS A;  1HXP A;  4NDG A;  3OXK A;  3KSV A;  4QEB A;  3LB5 A;  4NJZ A;  3BL7 A;  3OHE A;  1AV5 A;  1GUP A;  3I4S A;  4QDV A;  3N1T A;  3SZQ A;  1KPA A;  1FHI A;  3P0T A;  5FIT A;  4EQE A;  6FIT A;  1KPF A;  4NK0 A;  4FIT A;  1HXQ A;  1KPC A;  1ST0 A;  4EQG A;  5ED3 A;  4NDF A;  3NRD A;  2OIK A;  4RHN A;  4INC A;  5RHN A;  5IPD A;  4YKL B;  2Q4H A;  3OJ7 A;  4ZGL A;  5CS2 A;  1FIT A;  3O1Z A;  2EO4 A;  4NJY A;  2FIT A;  3SPD A;  2H39 A;  3SPL A;  4NDH A;  3QGZ A;  1Y23 A;  4QDE A;  3I24 A;  4XBA A;  1Z84 A;  3FIT A;  3R6F A;  5I2E A;  3BL9 A;  3WO5 A;  3OMF A;  3TW2 A;  5IN3 A;  4NJX A;  5EMT A;  1XMM A;  4INI A;  4EGU A;  4ZKV A;  5BV3 A;  4EQH A;  3L7X A;  1ST4 A;  3ANO A;  5IPC A;  2FHI A;  3O0M A;  5I2F A; 
#chains in the Genus database with same CATH topology
 1ZWJ A;  1KPE A;  2Q4L A;  1KPB A;  2LJW A;  5IPE A;  3O1X A;  3BLA A;  1GUQ A;  1VLR A;  3SP4 A;  3N1S A;  1RZY A;  3RHN A;  4NDI A;  1XML A;  4I5W A;  6RHN A;  4ZKL A;  5IPB A;  5ED6 A;  3IMI A;  3O1C A;  1EMS A;  1HXP A;  4NDG A;  3OXK A;  3KSV A;  4QEB A;  3LB5 A;  2GU0 A;  4NJZ A;  3BL7 A;  3OHE A;  1AV5 A;  1GUP A;  3I4S A;  4QDV A;  3N1T A;  3SZQ A;  1KPA A;  1FHI A;  3P0T A;  5FIT A;  4EQE A;  6FIT A;  1KPF A;  4NK0 A;  4FIT A;  1HXQ A;  2POF A;  2R7P A;  1KPC A;  1ST0 A;  4EQG A;  4G0A A;  5ED3 A;  4NDF A;  3NRD A;  2OIK A;  4RHN A;  4INC A;  5RHN A;  5IPD A;  4YKL B;  4I5T A;  2Q4H A;  3OJ7 A;  4ZGL A;  5CS2 A;  1FIT A;  1L9V A;  3O1Z A;  2EO4 A;  4NJY A;  2FIT A;  3SPD A;  2H39 A;  3SPL A;  4NDH A;  3QGZ A;  1Y23 A;  4QDE A;  3I24 A;  4XBA A;  1Z84 A;  3FIT A;  2R8F A;  3R6F A;  5I2E A;  3BL9 A;  3WO5 A;  3OMF A;  3TW2 A;  5IN3 A;  4NJX A;  5EMT A;  1XMM A;  4INI A;  4EGU A;  4ZKV A;  4G0J A;  4I5V A;  5BV3 A;  2R7J A;  4EQH A;  3L7X A;  2R7C A;  1ST4 A;  3ANO A;  5IPC A;  2FHI A;  3O0M A;  5I2F A; 
#chains in the Genus database with same CATH homology
 1ZWJ A;  1KPE A;  2Q4L A;  1KPB A;  5IPE A;  3O1X A;  3BLA A;  1GUQ A;  1VLR A;  3SP4 A;  3N1S A;  1RZY A;  3RHN A;  4NDI A;  1XML A;  6RHN A;  4ZKL A;  5IPB A;  5ED6 A;  3IMI A;  3O1C A;  1EMS A;  1HXP A;  4NDG A;  3OXK A;  3KSV A;  4QEB A;  3LB5 A;  4NJZ A;  3BL7 A;  3OHE A;  1AV5 A;  1GUP A;  3I4S A;  4QDV A;  3N1T A;  3SZQ A;  1KPA A;  1FHI A;  3P0T A;  5FIT A;  4EQE A;  6FIT A;  1KPF A;  4NK0 A;  4FIT A;  1HXQ A;  1KPC A;  1ST0 A;  4EQG A;  5ED3 A;  4NDF A;  3NRD A;  2OIK A;  4RHN A;  4INC A;  5RHN A;  5IPD A;  4YKL B;  2Q4H A;  3OJ7 A;  4ZGL A;  5CS2 A;  1FIT A;  3O1Z A;  2EO4 A;  4NJY A;  2FIT A;  3SPD A;  2H39 A;  3SPL A;  4NDH A;  3QGZ A;  1Y23 A;  4QDE A;  3I24 A;  4XBA A;  1Z84 A;  3FIT A;  3R6F A;  5I2E A;  3BL9 A;  3WO5 A;  3OMF A;  3TW2 A;  5IN3 A;  4NJX A;  5EMT A;  1XMM A;  4INI A;  4EGU A;  4ZKV A;  5BV3 A;  4EQH A;  3L7X A;  1ST4 A;  3ANO A;  5IPC A;  2FHI A;  3O0M A;  5I2F A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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