3O0MA

Crystal structure of a zn-bound histidine triad family protein from mycobacterium smegmatis
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
145
structure length
139
Chain Sequence
GSMSCVFCAIVSGDAPAIRIYEDENFLGILDIRPFTRGHTLVIPKTHTVDLTDTPPETVAGMAAVGQRIARAARESGLHADGNNIAINDGKAAFQTVFHIHLHVVPRRNGDKLSFRRDPDREESGRLLRAALAQLDSAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium smegmatis str. mc2 155
molecule keywords HIT family protein
total genus 44
structure length 139
sequence length 145
chains with identical sequence B
ec nomenclature
pdb deposition date 2010-07-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o0mA00
1GUQA 3BLAA 1ST4A 4NK0A 5I2EA 3FITA 1XMMA 1HXPA 1ZWJA 4ZKLA 5IN3A 4QEBA 1KPCA 4NDGA 3I24A 4FITA 1EMSA 1XMLA 2Q4LA 6FITA 3O1XA 1FHIA 4NDHA 3N1SA 5IPEA 3TW2A 2OIKA 3RHNA 1VLRA 5IPBA 1KPAA 5FITA 2FHIA 5I2FA 1ST0A 3N1TA 1KPEA 2H39A 4EQEA 1GUPA 1KPFA 4EGUA 1Z84A 4YKLB 6RHNA 4INIA 1KPBA 4QDVA 3OMFA 3BL9A 5IPCA 5IPDA 4NJYA 4NJZA 3ANOA 4EQGA 1RZYA 3KSVA 4EQHA 2Q4HA 3SPDA 1FITA 3QGZA 4ZKVA 2FITA 4NDFA 4NDIA 1AV5A 5BV3A 5CS2A 5ED6A 2EO4A 3R6FA 3WO5A 1Y23A 3O0MA 3P0TA 4RHNA 3BL7A 3O1ZA 3SZQA 3O1CA 3I4SA 4INCA 4XBAA 3OJ7A 1HXQA 4QDEA 3IMIA 3SPLA 3OHEA 5EMTA 3SP4A 4NJXA 3LB5A 3NRDA 5ED3A 5RHNA 4ZGLA 3L7XA 3OXKA
chains in the Genus database with same CATH superfamily
1GUQA 3BLAA 2R7JA 1ST4A 4I5VA 4NK0A 5I2EA 3FITA 1XMMA 1HXPA 1ZWJA 4ZKLA 5IN3A 4QEBA 1KPCA 4NDGA 3I24A 4FITA 1EMSA 1XMLA 2Q4LA 6FITA 3O1XA 1FHIA 4I5WA 4NDHA 4G0AA 3N1SA 5IPEA 3TW2A 2OIKA 3RHNA 1VLRA 5IPBA 1KPAA 5FITA 2FHIA 5I2FA 1ST0A 3N1TA 1KPEA 2H39A 4EQEA 1GUPA 1KPFA 4EGUA 1Z84A 4YKLB 6RHNA 4INIA 1KPBA 4QDVA 3OMFA 3BL9A 5IPCA 5IPDA 4NJYA 4NJZA 3ANOA 4EQGA 1RZYA 3KSVA 4EQHA 2Q4HA 3SPDA 1FITA 4I5TA 2R7PA 3QGZA 4ZKVA 1L9VA 2FITA 4NDFA 4NDIA 1AV5A 5BV3A 5CS2A 2GU0A 5ED6A 2POFA 2EO4A 3R6FA 3WO5A 1Y23A 3O0MA 3P0TA 4RHNA 3BL7A 3O1ZA 2R8FA 3SZQA 3O1CA 3I4SA 4INCA 4XBAA 3OJ7A 1HXQA 4G0JA 4QDEA 2R7CA 3IMIA 3SPLA 3OHEA 2LJWA 5EMTA 3SP4A 4NJXA 3LB5A 3NRDA 5ED3A 5RHNA 4ZGLA 3L7XA 3OXKA
chains in the Genus database with same CATH topology
1GUQA 3BLAA 1ST4A 4NK0A 5I2EA 3FITA 1XMMA 1HXPA 1ZWJA 4ZKLA 5IN3A 4QEBA 1KPCA 4NDGA 3I24A 4FITA 1EMSA 1XMLA 2Q4LA 6FITA 3O1XA 1FHIA 4NDHA 3N1SA 5IPEA 3TW2A 2OIKA 3RHNA 1VLRA 5IPBA 1KPAA 5FITA 2FHIA 5I2FA 1ST0A 3N1TA 1KPEA 2H39A 4EQEA 1GUPA 1KPFA 4EGUA 1Z84A 4YKLB 6RHNA 4INIA 1KPBA 4QDVA 3OMFA 3BL9A 5IPCA 5IPDA 4NJYA 4NJZA 3ANOA 4EQGA 1RZYA 3KSVA 4EQHA 2Q4HA 3SPDA 1FITA 3QGZA 4ZKVA 2FITA 4NDFA 4NDIA 1AV5A 5BV3A 5CS2A 5ED6A 2EO4A 3R6FA 3WO5A 1Y23A 3O0MA 3P0TA 4RHNA 3BL7A 3O1ZA 3SZQA 3O1CA 3I4SA 4INCA 4XBAA 3OJ7A 1HXQA 4QDEA 3IMIA 3SPLA 3OHEA 5EMTA 3SP4A 4NJXA 3LB5A 3NRDA 5ED3A 5RHNA 4ZGLA 3L7XA 3OXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GUQ A;  3BLA A;  1ST4 A;  4NK0 A;  5I2E A;  3FIT A;  1XMM A;  1HXP A;  1ZWJ A;  4ZKL A;  5IN3 A;  4QEB A;  1KPC A;  4NDG A;  3I24 A;  4FIT A;  1EMS A;  1XML A;  2Q4L A;  6FIT A;  3O1X A;  1FHI A;  4NDH A;  3N1S A;  5IPE A;  3TW2 A;  2OIK A;  3RHN A;  1VLR A;  5IPB A;  1KPA A;  5FIT A;  2FHI A;  5I2F A;  1ST0 A;  3N1T A;  1KPE A;  2H39 A;  4EQE A;  1GUP A;  1KPF A;  4EGU A;  1Z84 A;  4YKL B;  6RHN A;  4INI A;  1KPB A;  4QDV A;  3OMF A;  3BL9 A;  5IPC A;  5IPD A;  4NJY A;  4NJZ A;  3ANO A;  4EQG A;  1RZY A;  3KSV A;  4EQH A;  2Q4H A;  3SPD A;  1FIT A;  3QGZ A;  4ZKV A;  2FIT A;  4NDF A;  4NDI A;  1AV5 A;  5BV3 A;  5CS2 A;  5ED6 A;  2EO4 A;  3R6F A;  3WO5 A;  1Y23 A;  3O0M A;  3P0T A;  4RHN A;  3BL7 A;  3O1Z A;  3SZQ A;  3O1C A;  3I4S A;  4INC A;  4XBA A;  3OJ7 A;  1HXQ A;  4QDE A;  3IMI A;  3SPL A;  3OHE A;  5EMT A;  3SP4 A;  4NJX A;  3LB5 A;  3NRD A;  5ED3 A;  5RHN A;  4ZGL A;  3L7X A;  3OXK A; 
#chains in the Genus database with same CATH topology
 1GUQ A;  3BLA A;  2R7J A;  1ST4 A;  4I5V A;  4NK0 A;  5I2E A;  3FIT A;  1XMM A;  1HXP A;  1ZWJ A;  4ZKL A;  5IN3 A;  4QEB A;  1KPC A;  4NDG A;  3I24 A;  4FIT A;  1EMS A;  1XML A;  2Q4L A;  6FIT A;  3O1X A;  1FHI A;  4I5W A;  4NDH A;  4G0A A;  3N1S A;  5IPE A;  3TW2 A;  2OIK A;  3RHN A;  1VLR A;  5IPB A;  1KPA A;  5FIT A;  2FHI A;  5I2F A;  1ST0 A;  3N1T A;  1KPE A;  2H39 A;  4EQE A;  1GUP A;  1KPF A;  4EGU A;  1Z84 A;  4YKL B;  6RHN A;  4INI A;  1KPB A;  4QDV A;  3OMF A;  3BL9 A;  5IPC A;  5IPD A;  4NJY A;  4NJZ A;  3ANO A;  4EQG A;  1RZY A;  3KSV A;  4EQH A;  2Q4H A;  3SPD A;  1FIT A;  4I5T A;  2R7P A;  3QGZ A;  4ZKV A;  1L9V A;  2FIT A;  4NDF A;  4NDI A;  1AV5 A;  5BV3 A;  5CS2 A;  2GU0 A;  5ED6 A;  2POF A;  2EO4 A;  3R6F A;  3WO5 A;  1Y23 A;  3O0M A;  3P0T A;  4RHN A;  3BL7 A;  3O1Z A;  2R8F A;  3SZQ A;  3O1C A;  3I4S A;  4INC A;  4XBA A;  3OJ7 A;  1HXQ A;  4G0J A;  4QDE A;  2R7C A;  3IMI A;  3SPL A;  3OHE A;  2LJW A;  5EMT A;  3SP4 A;  4NJX A;  3LB5 A;  3NRD A;  5ED3 A;  5RHN A;  4ZGL A;  3L7X A;  3OXK A; 
#chains in the Genus database with same CATH homology
 1GUQ A;  3BLA A;  1ST4 A;  4NK0 A;  5I2E A;  3FIT A;  1XMM A;  1HXP A;  1ZWJ A;  4ZKL A;  5IN3 A;  4QEB A;  1KPC A;  4NDG A;  3I24 A;  4FIT A;  1EMS A;  1XML A;  2Q4L A;  6FIT A;  3O1X A;  1FHI A;  4NDH A;  3N1S A;  5IPE A;  3TW2 A;  2OIK A;  3RHN A;  1VLR A;  5IPB A;  1KPA A;  5FIT A;  2FHI A;  5I2F A;  1ST0 A;  3N1T A;  1KPE A;  2H39 A;  4EQE A;  1GUP A;  1KPF A;  4EGU A;  1Z84 A;  4YKL B;  6RHN A;  4INI A;  1KPB A;  4QDV A;  3OMF A;  3BL9 A;  5IPC A;  5IPD A;  4NJY A;  4NJZ A;  3ANO A;  4EQG A;  1RZY A;  3KSV A;  4EQH A;  2Q4H A;  3SPD A;  1FIT A;  3QGZ A;  4ZKV A;  2FIT A;  4NDF A;  4NDI A;  1AV5 A;  5BV3 A;  5CS2 A;  5ED6 A;  2EO4 A;  3R6F A;  3WO5 A;  1Y23 A;  3O0M A;  3P0T A;  4RHN A;  3BL7 A;  3O1Z A;  3SZQ A;  3O1C A;  3I4S A;  4INC A;  4XBA A;  3OJ7 A;  1HXQ A;  4QDE A;  3IMI A;  3SPL A;  3OHE A;  5EMT A;  3SP4 A;  4NJX A;  3LB5 A;  3NRD A;  5ED3 A;  5RHN A;  4ZGL A;  3L7X A;  3OXK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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