3O1CA

High resolution crystal structure of histidine triad nucleotide-binding protein 1 (hint1) c38a mutant from rabbit complexed with adenosine
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
115
structure length
115
Chain Sequence
RPGGDTIFGKIIRKEIPAKIIFEDDQALAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKCAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 30
structure length 115
sequence length 115
ec nomenclature ec 3.-.-.-:
pdb deposition date 2010-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o1cA00
4NDIA 5ED3A 4NDFA 1GUQA 4NJYA 4INCA 5IPBA 4NJXA 4RHNA 5IPEA 1KPEA 3O0MA 4ZKVA 4YKLB 3SPLA 3RHNA 3LB5A 4ZKLA 2Q4HA 1ST4A 3O1ZA 3IMIA 1Y23A 3R6FA 5FITA 4EQEA 3SPDA 2H39A 5ED6A 3NRDA 3KSVA 4QDEA 5IN3A 4ZGLA 2FITA 1RZYA 3WO5A 4EQHA 1KPAA 1ZWJA 3N1TA 1GUPA 6FITA 5EMTA 5BV3A 1FHIA 1XMMA 4FITA 1ST0A 5I2EA 5CS2A 3N1SA 3TW2A 3QGZA 1KPBA 2FHIA 3SP4A 1HXQA 4XBAA 3O1XA 1AV5A 3BL9A 4NK0A 4NDGA 3I24A 1KPCA 3L7XA 4INIA 6RHNA 3OXKA 1Z84A 4NDHA 3FITA 2EO4A 5IPCA 3I4SA 4EGUA 5IPDA 2OIKA 3O1CA 1EMSA 3OJ7A 5I2FA 3SZQA 1VLRA 3ANOA 1FITA 3OMFA 5RHNA 1XMLA 3OHEA 2Q4LA 4QEBA 3BLAA 4EQGA 4QDVA 3P0TA 1KPFA 4NJZA 3BL7A 1HXPA
chains in the Genus database with same CATH superfamily
4NDIA 5ED3A 4NDFA 1GUQA 4NJYA 4I5TA 4INCA 5IPBA 4NJXA 4RHNA 5IPEA 1KPEA 3O0MA 4ZKVA 4YKLB 3SPLA 2R7CA 3RHNA 3LB5A 4ZKLA 2Q4HA 1ST4A 3O1ZA 3IMIA 1Y23A 2R8FA 3R6FA 5FITA 4EQEA 3SPDA 2H39A 5ED6A 4G0JA 3NRDA 3KSVA 4QDEA 5IN3A 4I5WA 4ZGLA 2FITA 1RZYA 3WO5A 4EQHA 1KPAA 1ZWJA 3N1TA 1GUPA 6FITA 5EMTA 5BV3A 2LJWA 1FHIA 1XMMA 4FITA 2POFA 1L9VA 1ST0A 5I2EA 5CS2A 3N1SA 3TW2A 2GU0A 3QGZA 1KPBA 2FHIA 3SP4A 1HXQA 4XBAA 3O1XA 2R7JA 1AV5A 3BL9A 4NK0A 4NDGA 3I24A 1KPCA 3L7XA 4INIA 6RHNA 3OXKA 1Z84A 4G0AA 4NDHA 3FITA 2EO4A 5IPCA 3I4SA 4EGUA 5IPDA 2OIKA 3O1CA 1EMSA 3OJ7A 5I2FA 3SZQA 1VLRA 3ANOA 1FITA 3OMFA 5RHNA 1XMLA 3OHEA 2Q4LA 4QEBA 3BLAA 4EQGA 4QDVA 3P0TA 1KPFA 4NJZA 3BL7A 4I5VA 2R7PA 1HXPA
chains in the Genus database with same CATH topology
4NDIA 5ED3A 4NDFA 1GUQA 4NJYA 4INCA 5IPBA 4NJXA 4RHNA 5IPEA 1KPEA 3O0MA 4ZKVA 4YKLB 3SPLA 3RHNA 3LB5A 4ZKLA 2Q4HA 1ST4A 3O1ZA 3IMIA 1Y23A 3R6FA 5FITA 4EQEA 3SPDA 2H39A 5ED6A 3NRDA 3KSVA 4QDEA 5IN3A 4ZGLA 2FITA 1RZYA 3WO5A 4EQHA 1KPAA 1ZWJA 3N1TA 1GUPA 6FITA 5EMTA 5BV3A 1FHIA 1XMMA 4FITA 1ST0A 5I2EA 5CS2A 3N1SA 3TW2A 3QGZA 1KPBA 2FHIA 3SP4A 1HXQA 4XBAA 3O1XA 1AV5A 3BL9A 4NK0A 4NDGA 3I24A 1KPCA 3L7XA 4INIA 6RHNA 3OXKA 1Z84A 4NDHA 3FITA 2EO4A 5IPCA 3I4SA 4EGUA 5IPDA 2OIKA 3O1CA 1EMSA 3OJ7A 5I2FA 3SZQA 1VLRA 3ANOA 1FITA 3OMFA 5RHNA 1XMLA 3OHEA 2Q4LA 4QEBA 3BLAA 4EQGA 4QDVA 3P0TA 1KPFA 4NJZA 3BL7A 1HXPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NDI A;  5ED3 A;  4NDF A;  1GUQ A;  4NJY A;  4INC A;  5IPB A;  4NJX A;  4RHN A;  5IPE A;  1KPE A;  3O0M A;  4ZKV A;  4YKL B;  3SPL A;  3RHN A;  3LB5 A;  4ZKL A;  2Q4H A;  1ST4 A;  3O1Z A;  3IMI A;  1Y23 A;  3R6F A;  5FIT A;  4EQE A;  3SPD A;  2H39 A;  5ED6 A;  3NRD A;  3KSV A;  4QDE A;  5IN3 A;  4ZGL A;  2FIT A;  1RZY A;  3WO5 A;  4EQH A;  1KPA A;  1ZWJ A;  3N1T A;  1GUP A;  6FIT A;  5EMT A;  5BV3 A;  1FHI A;  1XMM A;  4FIT A;  1ST0 A;  5I2E A;  5CS2 A;  3N1S A;  3TW2 A;  3QGZ A;  1KPB A;  2FHI A;  3SP4 A;  1HXQ A;  4XBA A;  3O1X A;  1AV5 A;  3BL9 A;  4NK0 A;  4NDG A;  3I24 A;  1KPC A;  3L7X A;  4INI A;  6RHN A;  3OXK A;  1Z84 A;  4NDH A;  3FIT A;  2EO4 A;  5IPC A;  3I4S A;  4EGU A;  5IPD A;  2OIK A;  3O1C A;  1EMS A;  3OJ7 A;  5I2F A;  3SZQ A;  1VLR A;  3ANO A;  1FIT A;  3OMF A;  5RHN A;  1XML A;  3OHE A;  2Q4L A;  4QEB A;  3BLA A;  4EQG A;  4QDV A;  3P0T A;  1KPF A;  4NJZ A;  3BL7 A;  1HXP A; 
#chains in the Genus database with same CATH topology
 4NDI A;  5ED3 A;  4NDF A;  1GUQ A;  4NJY A;  4I5T A;  4INC A;  5IPB A;  4NJX A;  4RHN A;  5IPE A;  1KPE A;  3O0M A;  4ZKV A;  4YKL B;  3SPL A;  2R7C A;  3RHN A;  3LB5 A;  4ZKL A;  2Q4H A;  1ST4 A;  3O1Z A;  3IMI A;  1Y23 A;  2R8F A;  3R6F A;  5FIT A;  4EQE A;  3SPD A;  2H39 A;  5ED6 A;  4G0J A;  3NRD A;  3KSV A;  4QDE A;  5IN3 A;  4I5W A;  4ZGL A;  2FIT A;  1RZY A;  3WO5 A;  4EQH A;  1KPA A;  1ZWJ A;  3N1T A;  1GUP A;  6FIT A;  5EMT A;  5BV3 A;  2LJW A;  1FHI A;  1XMM A;  4FIT A;  2POF A;  1L9V A;  1ST0 A;  5I2E A;  5CS2 A;  3N1S A;  3TW2 A;  2GU0 A;  3QGZ A;  1KPB A;  2FHI A;  3SP4 A;  1HXQ A;  4XBA A;  3O1X A;  2R7J A;  1AV5 A;  3BL9 A;  4NK0 A;  4NDG A;  3I24 A;  1KPC A;  3L7X A;  4INI A;  6RHN A;  3OXK A;  1Z84 A;  4G0A A;  4NDH A;  3FIT A;  2EO4 A;  5IPC A;  3I4S A;  4EGU A;  5IPD A;  2OIK A;  3O1C A;  1EMS A;  3OJ7 A;  5I2F A;  3SZQ A;  1VLR A;  3ANO A;  1FIT A;  3OMF A;  5RHN A;  1XML A;  3OHE A;  2Q4L A;  4QEB A;  3BLA A;  4EQG A;  4QDV A;  3P0T A;  1KPF A;  4NJZ A;  3BL7 A;  4I5V A;  2R7P A;  1HXP A; 
#chains in the Genus database with same CATH homology
 4NDI A;  5ED3 A;  4NDF A;  1GUQ A;  4NJY A;  4INC A;  5IPB A;  4NJX A;  4RHN A;  5IPE A;  1KPE A;  3O0M A;  4ZKV A;  4YKL B;  3SPL A;  3RHN A;  3LB5 A;  4ZKL A;  2Q4H A;  1ST4 A;  3O1Z A;  3IMI A;  1Y23 A;  3R6F A;  5FIT A;  4EQE A;  3SPD A;  2H39 A;  5ED6 A;  3NRD A;  3KSV A;  4QDE A;  5IN3 A;  4ZGL A;  2FIT A;  1RZY A;  3WO5 A;  4EQH A;  1KPA A;  1ZWJ A;  3N1T A;  1GUP A;  6FIT A;  5EMT A;  5BV3 A;  1FHI A;  1XMM A;  4FIT A;  1ST0 A;  5I2E A;  5CS2 A;  3N1S A;  3TW2 A;  3QGZ A;  1KPB A;  2FHI A;  3SP4 A;  1HXQ A;  4XBA A;  3O1X A;  1AV5 A;  3BL9 A;  4NK0 A;  4NDG A;  3I24 A;  1KPC A;  3L7X A;  4INI A;  6RHN A;  3OXK A;  1Z84 A;  4NDH A;  3FIT A;  2EO4 A;  5IPC A;  3I4S A;  4EGU A;  5IPD A;  2OIK A;  3O1C A;  1EMS A;  3OJ7 A;  5I2F A;  3SZQ A;  1VLR A;  3ANO A;  1FIT A;  3OMF A;  5RHN A;  1XML A;  3OHE A;  2Q4L A;  4QEB A;  3BLA A;  4EQG A;  4QDV A;  3P0T A;  1KPF A;  4NJZ A;  3BL7 A;  1HXP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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