3O1CA

High resolution crystal structure of histidine triad nucleotide-binding protein 1 (hint1) c38a mutant from rabbit complexed with adenosine
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
115
structure length
115
Chain Sequence
RPGGDTIFGKIIRKEIPAKIIFEDDQALAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKCAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 30
structure length 115
sequence length 115
ec nomenclature ec 3.-.-.-:
pdb deposition date 2010-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o1cA00
4YKLB 5IPBA 4NDHA 3OJ7A 2EO4A 5CS2A 4NJXA 4NJYA 3BL7A 1HXQA 4QDEA 3QGZA 3P0TA 5FITA 4QDVA 1ZWJA 4NDIA 1Z84A 5ED6A 5I2FA 4ZGLA 1GUQA 4EQEA 5IPCA 6RHNA 5EMTA 1FHIA 1XMMA 3LB5A 4EQHA 3SPDA 1FITA 3L7XA 2FITA 3N1TA 1ST4A 4ZKVA 2H39A 3TW2A 1KPEA 3R6FA 3KSVA 4NK0A 2FHIA 4XBAA 5I2EA 3O1ZA 3BL9A 3SP4A 3I4SA 3O1XA 3SZQA 4INCA 4EGUA 3O0MA 3OHEA 4FITA 4EQGA 6FITA 1XMLA 5IPDA 2Q4LA 3O1CA 1AV5A 5ED3A 3ANOA 4INIA 4NDGA 1HXPA 1VLRA 3I24A 4NDFA 3BLAA 4ZKLA 2OIKA 5RHNA 1EMSA 4NJZA 3OMFA 3FITA 3SPLA 5BV3A 3WO5A 3N1SA 1ST0A 5IN3A 3OXKA 5IPEA 3NRDA 1RZYA 3RHNA 2Q4HA 1GUPA 1KPAA 4QEBA 3IMIA 1Y23A 1KPBA 4RHNA 1KPCA 1KPFA
chains in the Genus database with same CATH superfamily
4YKLB 5IPBA 4NDHA 3OJ7A 2EO4A 5CS2A 4NJXA 4NJYA 3BL7A 1HXQA 2R7PA 4QDEA 3QGZA 3P0TA 5FITA 4QDVA 1ZWJA 4NDIA 1Z84A 5ED6A 5I2FA 4ZGLA 1GUQA 4EQEA 5IPCA 1L9VA 6RHNA 5EMTA 1FHIA 1XMMA 3LB5A 4EQHA 4G0JA 3SPDA 1FITA 3L7XA 2FITA 3N1TA 1ST4A 4ZKVA 2H39A 3TW2A 1KPEA 3R6FA 3KSVA 4G0AA 4NK0A 2FHIA 4XBAA 5I2EA 3O1ZA 3BL9A 3SP4A 3I4SA 3O1XA 3SZQA 4INCA 4EGUA 3O0MA 3OHEA 4FITA 4I5VA 4EQGA 6FITA 1XMLA 5IPDA 2Q4LA 2GU0A 3O1CA 1AV5A 5ED3A 3ANOA 4INIA 4NDGA 1HXPA 1VLRA 3I24A 4NDFA 3BLAA 4ZKLA 2OIKA 5RHNA 1EMSA 2LJWA 4I5TA 4NJZA 2R7CA 3OMFA 3FITA 3SPLA 5BV3A 3WO5A 3N1SA 1ST0A 2R8FA 5IN3A 3OXKA 5IPEA 3NRDA 1RZYA 4I5WA 2POFA 3RHNA 2Q4HA 1GUPA 1KPAA 4QEBA 3IMIA 1Y23A 1KPBA 4RHNA 1KPCA 2R7JA 1KPFA
chains in the Genus database with same CATH topology
4YKLB 5IPBA 4NDHA 3OJ7A 2EO4A 5CS2A 4NJXA 4NJYA 3BL7A 1HXQA 4QDEA 3QGZA 3P0TA 5FITA 4QDVA 1ZWJA 4NDIA 1Z84A 5ED6A 5I2FA 4ZGLA 1GUQA 4EQEA 5IPCA 6RHNA 5EMTA 1FHIA 1XMMA 3LB5A 4EQHA 3SPDA 1FITA 3L7XA 2FITA 3N1TA 1ST4A 4ZKVA 2H39A 3TW2A 1KPEA 3R6FA 3KSVA 4NK0A 2FHIA 4XBAA 5I2EA 3O1ZA 3BL9A 3SP4A 3I4SA 3O1XA 3SZQA 4INCA 4EGUA 3O0MA 3OHEA 4FITA 4EQGA 6FITA 1XMLA 5IPDA 2Q4LA 3O1CA 1AV5A 5ED3A 3ANOA 4INIA 4NDGA 1HXPA 1VLRA 3I24A 4NDFA 3BLAA 4ZKLA 2OIKA 5RHNA 1EMSA 4NJZA 3OMFA 3FITA 3SPLA 5BV3A 3WO5A 3N1SA 1ST0A 5IN3A 3OXKA 5IPEA 3NRDA 1RZYA 3RHNA 2Q4HA 1GUPA 1KPAA 4QEBA 3IMIA 1Y23A 1KPBA 4RHNA 1KPCA 1KPFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YKL B;  5IPB A;  4NDH A;  3OJ7 A;  2EO4 A;  5CS2 A;  4NJX A;  4NJY A;  3BL7 A;  1HXQ A;  4QDE A;  3QGZ A;  3P0T A;  5FIT A;  4QDV A;  1ZWJ A;  4NDI A;  1Z84 A;  5ED6 A;  5I2F A;  4ZGL A;  1GUQ A;  4EQE A;  5IPC A;  6RHN A;  5EMT A;  1FHI A;  1XMM A;  3LB5 A;  4EQH A;  3SPD A;  1FIT A;  3L7X A;  2FIT A;  3N1T A;  1ST4 A;  4ZKV A;  2H39 A;  3TW2 A;  1KPE A;  3R6F A;  3KSV A;  4NK0 A;  2FHI A;  4XBA A;  5I2E A;  3O1Z A;  3BL9 A;  3SP4 A;  3I4S A;  3O1X A;  3SZQ A;  4INC A;  4EGU A;  3O0M A;  3OHE A;  4FIT A;  4EQG A;  6FIT A;  1XML A;  5IPD A;  2Q4L A;  3O1C A;  1AV5 A;  5ED3 A;  3ANO A;  4INI A;  4NDG A;  1HXP A;  1VLR A;  3I24 A;  4NDF A;  3BLA A;  4ZKL A;  2OIK A;  5RHN A;  1EMS A;  4NJZ A;  3OMF A;  3FIT A;  3SPL A;  5BV3 A;  3WO5 A;  3N1S A;  1ST0 A;  5IN3 A;  3OXK A;  5IPE A;  3NRD A;  1RZY A;  3RHN A;  2Q4H A;  1GUP A;  1KPA A;  4QEB A;  3IMI A;  1Y23 A;  1KPB A;  4RHN A;  1KPC A;  1KPF A; 
#chains in the Genus database with same CATH topology
 4YKL B;  5IPB A;  4NDH A;  3OJ7 A;  2EO4 A;  5CS2 A;  4NJX A;  4NJY A;  3BL7 A;  1HXQ A;  2R7P A;  4QDE A;  3QGZ A;  3P0T A;  5FIT A;  4QDV A;  1ZWJ A;  4NDI A;  1Z84 A;  5ED6 A;  5I2F A;  4ZGL A;  1GUQ A;  4EQE A;  5IPC A;  1L9V A;  6RHN A;  5EMT A;  1FHI A;  1XMM A;  3LB5 A;  4EQH A;  4G0J A;  3SPD A;  1FIT A;  3L7X A;  2FIT A;  3N1T A;  1ST4 A;  4ZKV A;  2H39 A;  3TW2 A;  1KPE A;  3R6F A;  3KSV A;  4G0A A;  4NK0 A;  2FHI A;  4XBA A;  5I2E A;  3O1Z A;  3BL9 A;  3SP4 A;  3I4S A;  3O1X A;  3SZQ A;  4INC A;  4EGU A;  3O0M A;  3OHE A;  4FIT A;  4I5V A;  4EQG A;  6FIT A;  1XML A;  5IPD A;  2Q4L A;  2GU0 A;  3O1C A;  1AV5 A;  5ED3 A;  3ANO A;  4INI A;  4NDG A;  1HXP A;  1VLR A;  3I24 A;  4NDF A;  3BLA A;  4ZKL A;  2OIK A;  5RHN A;  1EMS A;  2LJW A;  4I5T A;  4NJZ A;  2R7C A;  3OMF A;  3FIT A;  3SPL A;  5BV3 A;  3WO5 A;  3N1S A;  1ST0 A;  2R8F A;  5IN3 A;  3OXK A;  5IPE A;  3NRD A;  1RZY A;  4I5W A;  2POF A;  3RHN A;  2Q4H A;  1GUP A;  1KPA A;  4QEB A;  3IMI A;  1Y23 A;  1KPB A;  4RHN A;  1KPC A;  2R7J A;  1KPF A; 
#chains in the Genus database with same CATH homology
 4YKL B;  5IPB A;  4NDH A;  3OJ7 A;  2EO4 A;  5CS2 A;  4NJX A;  4NJY A;  3BL7 A;  1HXQ A;  4QDE A;  3QGZ A;  3P0T A;  5FIT A;  4QDV A;  1ZWJ A;  4NDI A;  1Z84 A;  5ED6 A;  5I2F A;  4ZGL A;  1GUQ A;  4EQE A;  5IPC A;  6RHN A;  5EMT A;  1FHI A;  1XMM A;  3LB5 A;  4EQH A;  3SPD A;  1FIT A;  3L7X A;  2FIT A;  3N1T A;  1ST4 A;  4ZKV A;  2H39 A;  3TW2 A;  1KPE A;  3R6F A;  3KSV A;  4NK0 A;  2FHI A;  4XBA A;  5I2E A;  3O1Z A;  3BL9 A;  3SP4 A;  3I4S A;  3O1X A;  3SZQ A;  4INC A;  4EGU A;  3O0M A;  3OHE A;  4FIT A;  4EQG A;  6FIT A;  1XML A;  5IPD A;  2Q4L A;  3O1C A;  1AV5 A;  5ED3 A;  3ANO A;  4INI A;  4NDG A;  1HXP A;  1VLR A;  3I24 A;  4NDF A;  3BLA A;  4ZKL A;  2OIK A;  5RHN A;  1EMS A;  4NJZ A;  3OMF A;  3FIT A;  3SPL A;  5BV3 A;  3WO5 A;  3N1S A;  1ST0 A;  5IN3 A;  3OXK A;  5IPE A;  3NRD A;  1RZY A;  3RHN A;  2Q4H A;  1GUP A;  1KPA A;  4QEB A;  3IMI A;  1Y23 A;  1KPB A;  4RHN A;  1KPC A;  1KPF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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