3O1XA

High resolution crystal structure of histidine triad nucleotide-binding protein 1 (hint1) c84a mutant from rabbit complexed with adenosine
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
115
structure length
115
Chain Sequence
RPGGDTIFGKIIRKEIPAKIIFEDDQCLAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKAAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 29
structure length 115
sequence length 115
ec nomenclature ec 3.-.-.-:
pdb deposition date 2010-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o1xA00
1RZYA 1Z84A 5ED3A 4NDGA 4INCA 4QEBA 3R6FA 3BL9A 4XBAA 5IPCA 3O1ZA 3OMFA 4NDFA 1Y23A 2Q4LA 3LB5A 3OXKA 3SZQA 3SPDA 1FITA 1HXPA 3FITA 4EGUA 2FITA 3ANOA 1KPCA 3NRDA 3O1XA 5RHNA 5I2EA 4EQHA 4ZKLA 4NJXA 4EQEA 2H39A 2OIKA 3OJ7A 1KPAA 5IPDA 3I24A 1HXQA 5CS2A 3WO5A 3N1TA 1FHIA 3TW2A 1GUPA 1AV5A 3RHNA 5EMTA 1ZWJA 4RHNA 2Q4HA 3N1SA 4ZGLA 4FITA 1VLRA 1EMSA 1GUQA 1ST4A 5BV3A 4NDHA 4ZKVA 3P0TA 6FITA 1XMMA 5I2FA 5IPEA 5FITA 4NJZA 1XMLA 3O1CA 4EQGA 3BLAA 3L7XA 4NJYA 6RHNA 2EO4A 4QDVA 3SPLA 5IN3A 3OHEA 3QGZA 4NK0A 5ED6A 1KPFA 2FHIA 4INIA 4QDEA 3SP4A 3KSVA 3O0MA 4NDIA 1ST0A 3IMIA 1KPEA 3BL7A 3I4SA 4YKLB 5IPBA 1KPBA
chains in the Genus database with same CATH superfamily
1RZYA 1Z84A 5ED3A 4NDGA 4INCA 4QEBA 3R6FA 3BL9A 4XBAA 5IPCA 3O1ZA 3OMFA 2LJWA 4NDFA 1Y23A 2Q4LA 3LB5A 3OXKA 4G0AA 3SZQA 3SPDA 1FITA 2R8FA 1HXPA 3FITA 4I5TA 4EGUA 2FITA 3ANOA 1KPCA 3NRDA 3O1XA 5RHNA 5I2EA 4EQHA 4ZKLA 4NJXA 1L9VA 4EQEA 2H39A 2OIKA 2GU0A 2R7CA 3OJ7A 1KPAA 5IPDA 3I24A 1HXQA 5CS2A 3WO5A 3N1TA 1FHIA 1GUPA 3TW2A 1AV5A 2POFA 3RHNA 5EMTA 4G0JA 1ZWJA 4RHNA 2Q4HA 3N1SA 4I5WA 4ZGLA 4FITA 1VLRA 1EMSA 1GUQA 1ST4A 5BV3A 4NDHA 4I5VA 4ZKVA 3P0TA 6FITA 1XMMA 5I2FA 5IPEA 5FITA 4NJZA 1XMLA 2R7JA 3O1CA 4EQGA 3BLAA 3L7XA 4NJYA 6RHNA 2EO4A 4QDVA 3SPLA 5IN3A 3OHEA 3QGZA 4NK0A 5ED6A 1KPFA 2FHIA 4INIA 4QDEA 3SP4A 3KSVA 3O0MA 4NDIA 2R7PA 1ST0A 3IMIA 1KPEA 3BL7A 3I4SA 4YKLB 5IPBA 1KPBA
chains in the Genus database with same CATH topology
1RZYA 1Z84A 5ED3A 4NDGA 4INCA 4QEBA 3R6FA 3BL9A 4XBAA 5IPCA 3O1ZA 3OMFA 4NDFA 1Y23A 2Q4LA 3LB5A 3OXKA 3SZQA 3SPDA 1FITA 1HXPA 3FITA 4EGUA 2FITA 3ANOA 1KPCA 3NRDA 3O1XA 5RHNA 5I2EA 4EQHA 4ZKLA 4NJXA 4EQEA 2H39A 2OIKA 3OJ7A 1KPAA 5IPDA 3I24A 1HXQA 5CS2A 3WO5A 3N1TA 1FHIA 3TW2A 1GUPA 1AV5A 3RHNA 5EMTA 1ZWJA 4RHNA 2Q4HA 3N1SA 4ZGLA 4FITA 1VLRA 1EMSA 1GUQA 1ST4A 5BV3A 4NDHA 4ZKVA 3P0TA 6FITA 1XMMA 5I2FA 5IPEA 5FITA 4NJZA 1XMLA 3O1CA 4EQGA 3BLAA 3L7XA 4NJYA 6RHNA 2EO4A 4QDVA 3SPLA 5IN3A 3OHEA 3QGZA 4NK0A 5ED6A 1KPFA 2FHIA 4INIA 4QDEA 3SP4A 3KSVA 3O0MA 4NDIA 1ST0A 3IMIA 1KPEA 3BL7A 3I4SA 4YKLB 5IPBA 1KPBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RZY A;  1Z84 A;  5ED3 A;  4NDG A;  4INC A;  4QEB A;  3R6F A;  3BL9 A;  4XBA A;  5IPC A;  3O1Z A;  3OMF A;  4NDF A;  1Y23 A;  2Q4L A;  3LB5 A;  3OXK A;  3SZQ A;  3SPD A;  1FIT A;  1HXP A;  3FIT A;  4EGU A;  2FIT A;  3ANO A;  1KPC A;  3NRD A;  3O1X A;  5RHN A;  5I2E A;  4EQH A;  4ZKL A;  4NJX A;  4EQE A;  2H39 A;  2OIK A;  3OJ7 A;  1KPA A;  5IPD A;  3I24 A;  1HXQ A;  5CS2 A;  3WO5 A;  3N1T A;  1FHI A;  3TW2 A;  1GUP A;  1AV5 A;  3RHN A;  5EMT A;  1ZWJ A;  4RHN A;  2Q4H A;  3N1S A;  4ZGL A;  4FIT A;  1VLR A;  1EMS A;  1GUQ A;  1ST4 A;  5BV3 A;  4NDH A;  4ZKV A;  3P0T A;  6FIT A;  1XMM A;  5I2F A;  5IPE A;  5FIT A;  4NJZ A;  1XML A;  3O1C A;  4EQG A;  3BLA A;  3L7X A;  4NJY A;  6RHN A;  2EO4 A;  4QDV A;  3SPL A;  5IN3 A;  3OHE A;  3QGZ A;  4NK0 A;  5ED6 A;  1KPF A;  2FHI A;  4INI A;  4QDE A;  3SP4 A;  3KSV A;  3O0M A;  4NDI A;  1ST0 A;  3IMI A;  1KPE A;  3BL7 A;  3I4S A;  4YKL B;  5IPB A;  1KPB A; 
#chains in the Genus database with same CATH topology
 1RZY A;  1Z84 A;  5ED3 A;  4NDG A;  4INC A;  4QEB A;  3R6F A;  3BL9 A;  4XBA A;  5IPC A;  3O1Z A;  3OMF A;  2LJW A;  4NDF A;  1Y23 A;  2Q4L A;  3LB5 A;  3OXK A;  4G0A A;  3SZQ A;  3SPD A;  1FIT A;  2R8F A;  1HXP A;  3FIT A;  4I5T A;  4EGU A;  2FIT A;  3ANO A;  1KPC A;  3NRD A;  3O1X A;  5RHN A;  5I2E A;  4EQH A;  4ZKL A;  4NJX A;  1L9V A;  4EQE A;  2H39 A;  2OIK A;  2GU0 A;  2R7C A;  3OJ7 A;  1KPA A;  5IPD A;  3I24 A;  1HXQ A;  5CS2 A;  3WO5 A;  3N1T A;  1FHI A;  1GUP A;  3TW2 A;  1AV5 A;  2POF A;  3RHN A;  5EMT A;  4G0J A;  1ZWJ A;  4RHN A;  2Q4H A;  3N1S A;  4I5W A;  4ZGL A;  4FIT A;  1VLR A;  1EMS A;  1GUQ A;  1ST4 A;  5BV3 A;  4NDH A;  4I5V A;  4ZKV A;  3P0T A;  6FIT A;  1XMM A;  5I2F A;  5IPE A;  5FIT A;  4NJZ A;  1XML A;  2R7J A;  3O1C A;  4EQG A;  3BLA A;  3L7X A;  4NJY A;  6RHN A;  2EO4 A;  4QDV A;  3SPL A;  5IN3 A;  3OHE A;  3QGZ A;  4NK0 A;  5ED6 A;  1KPF A;  2FHI A;  4INI A;  4QDE A;  3SP4 A;  3KSV A;  3O0M A;  4NDI A;  2R7P A;  1ST0 A;  3IMI A;  1KPE A;  3BL7 A;  3I4S A;  4YKL B;  5IPB A;  1KPB A; 
#chains in the Genus database with same CATH homology
 1RZY A;  1Z84 A;  5ED3 A;  4NDG A;  4INC A;  4QEB A;  3R6F A;  3BL9 A;  4XBA A;  5IPC A;  3O1Z A;  3OMF A;  4NDF A;  1Y23 A;  2Q4L A;  3LB5 A;  3OXK A;  3SZQ A;  3SPD A;  1FIT A;  1HXP A;  3FIT A;  4EGU A;  2FIT A;  3ANO A;  1KPC A;  3NRD A;  3O1X A;  5RHN A;  5I2E A;  4EQH A;  4ZKL A;  4NJX A;  4EQE A;  2H39 A;  2OIK A;  3OJ7 A;  1KPA A;  5IPD A;  3I24 A;  1HXQ A;  5CS2 A;  3WO5 A;  3N1T A;  1FHI A;  3TW2 A;  1GUP A;  1AV5 A;  3RHN A;  5EMT A;  1ZWJ A;  4RHN A;  2Q4H A;  3N1S A;  4ZGL A;  4FIT A;  1VLR A;  1EMS A;  1GUQ A;  1ST4 A;  5BV3 A;  4NDH A;  4ZKV A;  3P0T A;  6FIT A;  1XMM A;  5I2F A;  5IPE A;  5FIT A;  4NJZ A;  1XML A;  3O1C A;  4EQG A;  3BLA A;  3L7X A;  4NJY A;  6RHN A;  2EO4 A;  4QDV A;  3SPL A;  5IN3 A;  3OHE A;  3QGZ A;  4NK0 A;  5ED6 A;  1KPF A;  2FHI A;  4INI A;  4QDE A;  3SP4 A;  3KSV A;  3O0M A;  4NDI A;  1ST0 A;  3IMI A;  1KPE A;  3BL7 A;  3I4S A;  4YKL B;  5IPB A;  1KPB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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