3O1XA

High resolution crystal structure of histidine triad nucleotide-binding protein 1 (hint1) c84a mutant from rabbit complexed with adenosine
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
115
structure length
115
Chain Sequence
RPGGDTIFGKIIRKEIPAKIIFEDDQCLAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKAAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 29
structure length 115
sequence length 115
ec nomenclature ec 3.-.-.-:
pdb deposition date 2010-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o1xA00
3QGZA 3OHEA 2H39A 5IPCA 3I24A 3O1XA 3SP4A 3SPDA 1Y23A 4QDEA 3OXKA 3LB5A 3OJ7A 1ZWJA 4NDFA 3RHNA 2FHIA 5EMTA 4YKLB 4ZKVA 3O0MA 6FITA 3BLAA 1AV5A 5IPEA 4ZKLA 4INCA 4ZGLA 3FITA 5BV3A 3P0TA 2OIKA 5RHNA 5I2EA 4QDVA 1KPFA 3KSVA 5ED3A 4NDHA 1FITA 4EGUA 1XMLA 3N1TA 3WO5A 1Z84A 4EQEA 2EO4A 4NK0A 3O1ZA 5FITA 3I4SA 4NJZA 2Q4HA 3L7XA 3N1SA 2Q4LA 4NJXA 1ST4A 2FITA 3BL9A 4INIA 4NDGA 5IPDA 3ANOA 3BL7A 4NDIA 3IMIA 1VLRA 5IN3A 1FHIA 3TW2A 3OMFA 4EQHA 1GUQA 1KPEA 3SPLA 3NRDA 5ED6A 4QEBA 1GUPA 1ST0A 1HXQA 1XMMA 1KPCA 4NJYA 4RHNA 1HXPA 5CS2A 1KPBA 4EQGA 3R6FA 3O1CA 4FITA 3SZQA 1KPAA 5I2FA 1EMSA 4XBAA 5IPBA 1RZYA 6RHNA
chains in the Genus database with same CATH superfamily
3QGZA 3OHEA 2H39A 5IPCA 3I24A 3O1XA 3SP4A 3SPDA 1Y23A 4QDEA 3OXKA 3LB5A 3OJ7A 1ZWJA 4NDFA 3RHNA 2FHIA 5EMTA 4YKLB 4ZKVA 4G0AA 3O0MA 6FITA 3BLAA 1AV5A 5IPEA 4ZKLA 2R7JA 4INCA 4ZGLA 3FITA 5BV3A 3P0TA 2OIKA 5RHNA 5I2EA 4QDVA 1KPFA 3KSVA 5ED3A 4NDHA 1FITA 4EGUA 1XMLA 3N1TA 4I5WA 3WO5A 1L9VA 1Z84A 4EQEA 4G0JA 2EO4A 4NK0A 3O1ZA 5FITA 3I4SA 4NJZA 2Q4HA 3L7XA 3N1SA 2Q4LA 4I5VA 2R7PA 4NJXA 1ST4A 2FITA 3BL9A 4INIA 4I5TA 4NDGA 5IPDA 3ANOA 3BL7A 4NDIA 3IMIA 1VLRA 5IN3A 1FHIA 3TW2A 3OMFA 4EQHA 1GUQA 1KPEA 3SPLA 3NRDA 2R7CA 5ED6A 4QEBA 2GU0A 1GUPA 1ST0A 1HXQA 1XMMA 1KPCA 4NJYA 4RHNA 1HXPA 5CS2A 1KPBA 4EQGA 3R6FA 3O1CA 4FITA 3SZQA 2R8FA 1KPAA 5I2FA 2LJWA 1EMSA 2POFA 4XBAA 5IPBA 1RZYA 6RHNA
chains in the Genus database with same CATH topology
3QGZA 3OHEA 2H39A 5IPCA 3I24A 3O1XA 3SP4A 3SPDA 1Y23A 4QDEA 3OXKA 3LB5A 3OJ7A 1ZWJA 4NDFA 3RHNA 2FHIA 5EMTA 4YKLB 4ZKVA 3O0MA 6FITA 3BLAA 1AV5A 5IPEA 4ZKLA 4INCA 4ZGLA 3FITA 5BV3A 3P0TA 2OIKA 5RHNA 5I2EA 4QDVA 1KPFA 3KSVA 5ED3A 4NDHA 1FITA 4EGUA 1XMLA 3N1TA 3WO5A 1Z84A 4EQEA 2EO4A 4NK0A 3O1ZA 5FITA 3I4SA 4NJZA 2Q4HA 3L7XA 3N1SA 2Q4LA 4NJXA 1ST4A 2FITA 3BL9A 4INIA 4NDGA 5IPDA 3ANOA 3BL7A 4NDIA 3IMIA 1VLRA 5IN3A 1FHIA 3TW2A 3OMFA 4EQHA 1GUQA 1KPEA 3SPLA 3NRDA 5ED6A 4QEBA 1GUPA 1ST0A 1HXQA 1XMMA 1KPCA 4NJYA 4RHNA 1HXPA 5CS2A 1KPBA 4EQGA 3R6FA 3O1CA 4FITA 3SZQA 1KPAA 5I2FA 1EMSA 4XBAA 5IPBA 1RZYA 6RHNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QGZ A;  3OHE A;  2H39 A;  5IPC A;  3I24 A;  3O1X A;  3SP4 A;  3SPD A;  1Y23 A;  4QDE A;  3OXK A;  3LB5 A;  3OJ7 A;  1ZWJ A;  4NDF A;  3RHN A;  2FHI A;  5EMT A;  4YKL B;  4ZKV A;  3O0M A;  6FIT A;  3BLA A;  1AV5 A;  5IPE A;  4ZKL A;  4INC A;  4ZGL A;  3FIT A;  5BV3 A;  3P0T A;  2OIK A;  5RHN A;  5I2E A;  4QDV A;  1KPF A;  3KSV A;  5ED3 A;  4NDH A;  1FIT A;  4EGU A;  1XML A;  3N1T A;  3WO5 A;  1Z84 A;  4EQE A;  2EO4 A;  4NK0 A;  3O1Z A;  5FIT A;  3I4S A;  4NJZ A;  2Q4H A;  3L7X A;  3N1S A;  2Q4L A;  4NJX A;  1ST4 A;  2FIT A;  3BL9 A;  4INI A;  4NDG A;  5IPD A;  3ANO A;  3BL7 A;  4NDI A;  3IMI A;  1VLR A;  5IN3 A;  1FHI A;  3TW2 A;  3OMF A;  4EQH A;  1GUQ A;  1KPE A;  3SPL A;  3NRD A;  5ED6 A;  4QEB A;  1GUP A;  1ST0 A;  1HXQ A;  1XMM A;  1KPC A;  4NJY A;  4RHN A;  1HXP A;  5CS2 A;  1KPB A;  4EQG A;  3R6F A;  3O1C A;  4FIT A;  3SZQ A;  1KPA A;  5I2F A;  1EMS A;  4XBA A;  5IPB A;  1RZY A;  6RHN A; 
#chains in the Genus database with same CATH topology
 3QGZ A;  3OHE A;  2H39 A;  5IPC A;  3I24 A;  3O1X A;  3SP4 A;  3SPD A;  1Y23 A;  4QDE A;  3OXK A;  3LB5 A;  3OJ7 A;  1ZWJ A;  4NDF A;  3RHN A;  2FHI A;  5EMT A;  4YKL B;  4ZKV A;  4G0A A;  3O0M A;  6FIT A;  3BLA A;  1AV5 A;  5IPE A;  4ZKL A;  2R7J A;  4INC A;  4ZGL A;  3FIT A;  5BV3 A;  3P0T A;  2OIK A;  5RHN A;  5I2E A;  4QDV A;  1KPF A;  3KSV A;  5ED3 A;  4NDH A;  1FIT A;  4EGU A;  1XML A;  3N1T A;  4I5W A;  3WO5 A;  1L9V A;  1Z84 A;  4EQE A;  4G0J A;  2EO4 A;  4NK0 A;  3O1Z A;  5FIT A;  3I4S A;  4NJZ A;  2Q4H A;  3L7X A;  3N1S A;  2Q4L A;  4I5V A;  2R7P A;  4NJX A;  1ST4 A;  2FIT A;  3BL9 A;  4INI A;  4I5T A;  4NDG A;  5IPD A;  3ANO A;  3BL7 A;  4NDI A;  3IMI A;  1VLR A;  5IN3 A;  1FHI A;  3TW2 A;  3OMF A;  4EQH A;  1GUQ A;  1KPE A;  3SPL A;  3NRD A;  2R7C A;  5ED6 A;  4QEB A;  2GU0 A;  1GUP A;  1ST0 A;  1HXQ A;  1XMM A;  1KPC A;  4NJY A;  4RHN A;  1HXP A;  5CS2 A;  1KPB A;  4EQG A;  3R6F A;  3O1C A;  4FIT A;  3SZQ A;  2R8F A;  1KPA A;  5I2F A;  2LJW A;  1EMS A;  2POF A;  4XBA A;  5IPB A;  1RZY A;  6RHN A; 
#chains in the Genus database with same CATH homology
 3QGZ A;  3OHE A;  2H39 A;  5IPC A;  3I24 A;  3O1X A;  3SP4 A;  3SPD A;  1Y23 A;  4QDE A;  3OXK A;  3LB5 A;  3OJ7 A;  1ZWJ A;  4NDF A;  3RHN A;  2FHI A;  5EMT A;  4YKL B;  4ZKV A;  3O0M A;  6FIT A;  3BLA A;  1AV5 A;  5IPE A;  4ZKL A;  4INC A;  4ZGL A;  3FIT A;  5BV3 A;  3P0T A;  2OIK A;  5RHN A;  5I2E A;  4QDV A;  1KPF A;  3KSV A;  5ED3 A;  4NDH A;  1FIT A;  4EGU A;  1XML A;  3N1T A;  3WO5 A;  1Z84 A;  4EQE A;  2EO4 A;  4NK0 A;  3O1Z A;  5FIT A;  3I4S A;  4NJZ A;  2Q4H A;  3L7X A;  3N1S A;  2Q4L A;  4NJX A;  1ST4 A;  2FIT A;  3BL9 A;  4INI A;  4NDG A;  5IPD A;  3ANO A;  3BL7 A;  4NDI A;  3IMI A;  1VLR A;  5IN3 A;  1FHI A;  3TW2 A;  3OMF A;  4EQH A;  1GUQ A;  1KPE A;  3SPL A;  3NRD A;  5ED6 A;  4QEB A;  1GUP A;  1ST0 A;  1HXQ A;  1XMM A;  1KPC A;  4NJY A;  4RHN A;  1HXP A;  5CS2 A;  1KPB A;  4EQG A;  3R6F A;  3O1C A;  4FIT A;  3SZQ A;  1KPA A;  5I2F A;  1EMS A;  4XBA A;  5IPB A;  1RZY A;  6RHN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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