3O1ZA

High resolution crystal structure of histidine triad nucleotide-binding protein 1 (hint1) double cysteine mutant from rabbit
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
115
structure length
115
Chain Sequence
RPGGDTIFGKIIRKEIPAKIIFEDDQALAFHDISPQAPTHFLVIPKKHISQISAAEDADESLLGHLMIVGKKAAADLGLKKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMNWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
pubmed doi rcsb
molecule tags Hydrolase
source organism Oryctolagus cuniculus
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 27
structure length 115
sequence length 115
ec nomenclature ec 3.-.-.-:
pdb deposition date 2010-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3o1zA00
1RZYA 5IPEA 1HXQA 5I2FA 1KPCA 3O0MA 5RHNA 5I2EA 1EMSA 3KSVA 3BL9A 5ED6A 5EMTA 5BV3A 1Y23A 4NJXA 4QEBA 4EQHA 4NDGA 1FHIA 3N1SA 3I4SA 5IPBA 4EQGA 1VLRA 3SZQA 3IMIA 4NDFA 3O1ZA 4RHNA 2Q4LA 1ST4A 3I24A 3SP4A 4ZGLA 4INIA 5IPDA 3ANOA 4FITA 1FITA 1Z84A 2Q4HA 3LB5A 1KPEA 1KPFA 3FITA 2FITA 4QDVA 4ZKLA 3OXKA 4QDEA 3OHEA 1GUQA 1HXPA 3BLAA 5ED3A 4NK0A 1KPAA 4NDHA 5IPCA 1KPBA 4YKLB 3O1CA 2EO4A 3P0TA 6FITA 4NDIA 4NJZA 1ZWJA 2H39A 5IN3A 3OMFA 5FITA 1AV5A 3TW2A 3SPLA 3QGZA 2FHIA 4ZKVA 6RHNA 3L7XA 3R6FA 1GUPA 4EQEA 3OJ7A 4INCA 3O1XA 1XMLA 2OIKA 3N1TA 4XBAA 3RHNA 3SPDA 1XMMA 4NJYA 1ST0A 4EGUA 5CS2A 3BL7A 3NRDA 3WO5A
chains in the Genus database with same CATH superfamily
1RZYA 5IPEA 1HXQA 5I2FA 1L9VA 4I5WA 1KPCA 3O0MA 5RHNA 5I2EA 1EMSA 3KSVA 3BL9A 5ED6A 5EMTA 5BV3A 1Y23A 4NJXA 4QEBA 4EQHA 4NDGA 1FHIA 3N1SA 4I5TA 3I4SA 5IPBA 4EQGA 1VLRA 2LJWA 3SZQA 3IMIA 4NDFA 3O1ZA 4RHNA 2Q4LA 4G0AA 1ST4A 3I24A 3SP4A 4ZGLA 4INIA 5IPDA 3ANOA 4FITA 4G0JA 1FITA 1Z84A 2Q4HA 2POFA 2R7JA 3LB5A 1KPEA 1KPFA 3FITA 2FITA 4QDVA 4ZKLA 3OXKA 4QDEA 3OHEA 1GUQA 1HXPA 3BLAA 5ED3A 4NK0A 1KPAA 2GU0A 4NDHA 5IPCA 1KPBA 4YKLB 3O1CA 2EO4A 3P0TA 6FITA 4NDIA 2R7CA 4NJZA 1ZWJA 2H39A 2R8FA 5IN3A 3OMFA 5FITA 1AV5A 3TW2A 3SPLA 2R7PA 3QGZA 2FHIA 4ZKVA 6RHNA 3L7XA 3R6FA 1GUPA 4EQEA 3OJ7A 4INCA 3O1XA 1XMLA 2OIKA 3N1TA 4XBAA 3RHNA 3SPDA 1XMMA 4NJYA 1ST0A 4EGUA 5CS2A 3BL7A 3NRDA 4I5VA 3WO5A
chains in the Genus database with same CATH topology
1RZYA 5IPEA 1HXQA 5I2FA 1KPCA 3O0MA 5RHNA 5I2EA 1EMSA 3KSVA 3BL9A 5ED6A 5EMTA 5BV3A 1Y23A 4NJXA 4QEBA 4EQHA 4NDGA 1FHIA 3N1SA 3I4SA 5IPBA 4EQGA 1VLRA 3SZQA 3IMIA 4NDFA 3O1ZA 4RHNA 2Q4LA 1ST4A 3I24A 3SP4A 4ZGLA 4INIA 5IPDA 3ANOA 4FITA 1FITA 1Z84A 2Q4HA 3LB5A 1KPEA 1KPFA 3FITA 2FITA 4QDVA 4ZKLA 3OXKA 4QDEA 3OHEA 1GUQA 1HXPA 3BLAA 5ED3A 4NK0A 1KPAA 4NDHA 5IPCA 1KPBA 4YKLB 3O1CA 2EO4A 3P0TA 6FITA 4NDIA 4NJZA 1ZWJA 2H39A 5IN3A 3OMFA 5FITA 1AV5A 3TW2A 3SPLA 3QGZA 2FHIA 4ZKVA 6RHNA 3L7XA 3R6FA 1GUPA 4EQEA 3OJ7A 4INCA 3O1XA 1XMLA 2OIKA 3N1TA 4XBAA 3RHNA 3SPDA 1XMMA 4NJYA 1ST0A 4EGUA 5CS2A 3BL7A 3NRDA 3WO5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RZY A;  5IPE A;  1HXQ A;  5I2F A;  1KPC A;  3O0M A;  5RHN A;  5I2E A;  1EMS A;  3KSV A;  3BL9 A;  5ED6 A;  5EMT A;  5BV3 A;  1Y23 A;  4NJX A;  4QEB A;  4EQH A;  4NDG A;  1FHI A;  3N1S A;  3I4S A;  5IPB A;  4EQG A;  1VLR A;  3SZQ A;  3IMI A;  4NDF A;  3O1Z A;  4RHN A;  2Q4L A;  1ST4 A;  3I24 A;  3SP4 A;  4ZGL A;  4INI A;  5IPD A;  3ANO A;  4FIT A;  1FIT A;  1Z84 A;  2Q4H A;  3LB5 A;  1KPE A;  1KPF A;  3FIT A;  2FIT A;  4QDV A;  4ZKL A;  3OXK A;  4QDE A;  3OHE A;  1GUQ A;  1HXP A;  3BLA A;  5ED3 A;  4NK0 A;  1KPA A;  4NDH A;  5IPC A;  1KPB A;  4YKL B;  3O1C A;  2EO4 A;  3P0T A;  6FIT A;  4NDI A;  4NJZ A;  1ZWJ A;  2H39 A;  5IN3 A;  3OMF A;  5FIT A;  1AV5 A;  3TW2 A;  3SPL A;  3QGZ A;  2FHI A;  4ZKV A;  6RHN A;  3L7X A;  3R6F A;  1GUP A;  4EQE A;  3OJ7 A;  4INC A;  3O1X A;  1XML A;  2OIK A;  3N1T A;  4XBA A;  3RHN A;  3SPD A;  1XMM A;  4NJY A;  1ST0 A;  4EGU A;  5CS2 A;  3BL7 A;  3NRD A;  3WO5 A; 
#chains in the Genus database with same CATH topology
 1RZY A;  5IPE A;  1HXQ A;  5I2F A;  1L9V A;  4I5W A;  1KPC A;  3O0M A;  5RHN A;  5I2E A;  1EMS A;  3KSV A;  3BL9 A;  5ED6 A;  5EMT A;  5BV3 A;  1Y23 A;  4NJX A;  4QEB A;  4EQH A;  4NDG A;  1FHI A;  3N1S A;  4I5T A;  3I4S A;  5IPB A;  4EQG A;  1VLR A;  2LJW A;  3SZQ A;  3IMI A;  4NDF A;  3O1Z A;  4RHN A;  2Q4L A;  4G0A A;  1ST4 A;  3I24 A;  3SP4 A;  4ZGL A;  4INI A;  5IPD A;  3ANO A;  4FIT A;  4G0J A;  1FIT A;  1Z84 A;  2Q4H A;  2POF A;  2R7J A;  3LB5 A;  1KPE A;  1KPF A;  3FIT A;  2FIT A;  4QDV A;  4ZKL A;  3OXK A;  4QDE A;  3OHE A;  1GUQ A;  1HXP A;  3BLA A;  5ED3 A;  4NK0 A;  1KPA A;  2GU0 A;  4NDH A;  5IPC A;  1KPB A;  4YKL B;  3O1C A;  2EO4 A;  3P0T A;  6FIT A;  4NDI A;  2R7C A;  4NJZ A;  1ZWJ A;  2H39 A;  2R8F A;  5IN3 A;  3OMF A;  5FIT A;  1AV5 A;  3TW2 A;  3SPL A;  2R7P A;  3QGZ A;  2FHI A;  4ZKV A;  6RHN A;  3L7X A;  3R6F A;  1GUP A;  4EQE A;  3OJ7 A;  4INC A;  3O1X A;  1XML A;  2OIK A;  3N1T A;  4XBA A;  3RHN A;  3SPD A;  1XMM A;  4NJY A;  1ST0 A;  4EGU A;  5CS2 A;  3BL7 A;  3NRD A;  4I5V A;  3WO5 A; 
#chains in the Genus database with same CATH homology
 1RZY A;  5IPE A;  1HXQ A;  5I2F A;  1KPC A;  3O0M A;  5RHN A;  5I2E A;  1EMS A;  3KSV A;  3BL9 A;  5ED6 A;  5EMT A;  5BV3 A;  1Y23 A;  4NJX A;  4QEB A;  4EQH A;  4NDG A;  1FHI A;  3N1S A;  3I4S A;  5IPB A;  4EQG A;  1VLR A;  3SZQ A;  3IMI A;  4NDF A;  3O1Z A;  4RHN A;  2Q4L A;  1ST4 A;  3I24 A;  3SP4 A;  4ZGL A;  4INI A;  5IPD A;  3ANO A;  4FIT A;  1FIT A;  1Z84 A;  2Q4H A;  3LB5 A;  1KPE A;  1KPF A;  3FIT A;  2FIT A;  4QDV A;  4ZKL A;  3OXK A;  4QDE A;  3OHE A;  1GUQ A;  1HXP A;  3BLA A;  5ED3 A;  4NK0 A;  1KPA A;  4NDH A;  5IPC A;  1KPB A;  4YKL B;  3O1C A;  2EO4 A;  3P0T A;  6FIT A;  4NDI A;  4NJZ A;  1ZWJ A;  2H39 A;  5IN3 A;  3OMF A;  5FIT A;  1AV5 A;  3TW2 A;  3SPL A;  3QGZ A;  2FHI A;  4ZKV A;  6RHN A;  3L7X A;  3R6F A;  1GUP A;  4EQE A;  3OJ7 A;  4INC A;  3O1X A;  1XML A;  2OIK A;  3N1T A;  4XBA A;  3RHN A;  3SPD A;  1XMM A;  4NJY A;  1ST0 A;  4EGU A;  5CS2 A;  3BL7 A;  3NRD A;  3WO5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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