3QD6R

Crystal structure of the cd40 and cd154 (cd40l) complex
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
120
structure length
114
Chain Sequence
CREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQKGTSETDTICTCEEGWHCTSEACESCVLHRSCKQIATGVSDTICEP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytokine/cytokine receptor
source organism Homo sapiens
publication title Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation
pubmed doi rcsb
molecule keywords CD40 ligand
total genus 14
structure length 114
sequence length 120
chains with identical sequence S, T, U
ec nomenclature
pdb deposition date 2011-01-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 3qd6R01
3.10.360.30 Alpha Beta Roll Antimicrobial Peptide, Beta-defensin 2; Chain A Antimicrobial Peptide, Beta-defensin 2; Chain A 3qd6R02
1D4VA 3MHDD 3U3QA 2H9GR 3MI8D 5BNQR 4M4PA 4MSVB 1FT4A 3WVTA 3FL7A 3IJ2X 3QBQB 2HEVR 3X3FA 4GIQR 3BUKC 2AW2B 4KGQC 3U3TA 4N90R 3QO4A 5IHLA 4FHQA 4KGGC 3U3PA 2HEYR 1ZA3R 1DU3A 3U3SA 4RSUD 1D0GR 3ME2R 1EXTA 1JMAB 4E4DR 1TNRR 3K51B 5CIRE 5DMJA 2X10A 4M4RA 3TJEF 3ALQR 4MXWR 3ME4A 4YN0A 2UWIA 3U3VA 5L36B 1SG1X 3THMF 3QD6R 3MBWA 4J6GC 4BK5A 3URFZ 4OD2S 4I9XC 4BK4A 1NCFA
chains in the Genus database with same CATH superfamily
1D4VA 3MHDD 2E4WA 3U3QA 2H9GR 3MI8D 5BNQR 4M4PA 4MSVB 1FT4A 3WVTA 3FL7A 2E4UA 2LWLA 3IJ2X 3QBQB 2E4VA 2HEVR 4GIQR 3X3FA 1FD4A 2LXOA 3BUKC 2AW2B 4KGQC 3U3TA 4N90R 3QO4A 5IHLA 4FHQA 2MJKA 4KGGC 3U3PA 2HEYR 1ZA3R 1DU3A 3U3SA 4RSUD 1D0GR 2E4XA 3ME2R 1EXTA 1JMAB 4E4DR 1TNRR 3K51B 5CIRE 5DMJA 2X10A 4M4RA 3TJEF 3ALQR 4MXWR 3ME4A 4YN0A 2UWIA 3U3VA 2E4YA 5L36B 1SG1X 1FQQA 3THMF 3QD6R 3MBWA 4J6GC 4BK5A 3URFZ 2QR6A 4OD2S 1FD3A 1KJ6A 4I9XC 4BK4A 1NCFA
chains in the Genus database with same CATH topology
1D4VA 3MHDD 3U3QA 2H9GR 3MI8D 5BNQR 4M4PA 4MSVB 1FT4A 3WVTA 3FL7A 2LWLA 3IJ2X 3QBQB 2HEVR 3X3FA 4GIQR 1FD4A 2LXOA 3BUKC 2AW2B 4KGQC 3U3TA 4N90R 3QO4A 5IHLA 4FHQA 2MJKA 4KGGC 3U3PA 2HEYR 1ZA3R 1DU3A 3U3SA 4RSUD 1D0GR 3ME2R 1EXTA 1JMAB 4E4DR 1TNRR 3K51B 5CIRE 5DMJA 2X10A 4M4RA 3TJEF 3ALQR 4MXWR 3ME4A 4YN0A 2UWIA 3U3VA 5L36B 1SG1X 1FQQA 3THMF 3QD6R 3MBWA 4J6GC 4BK5A 3URFZ 4OD2S 1FD3A 1KJ6A 4I9XC 4BK4A 1NCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D4V A;  3MHD D;  3U3Q A;  2H9G R;  3MI8 D;  5BNQ R;  4M4P A;  4MSV B;  1FT4 A;  3WVT A;  3FL7 A;  3IJ2 X;  3QBQ B;  2HEV R;  3X3F A;  4GIQ R;  3BUK C;  2AW2 B;  4KGQ C;  3U3T A;  4N90 R;  3QO4 A;  5IHL A;  4FHQ A;  4KGG C;  3U3P A;  2HEY R;  1ZA3 R;  1DU3 A;  3U3S A;  4RSU D;  1D0G R;  3ME2 R;  1EXT A;  1JMA B;  4E4D R;  1TNR R;  3K51 B;  5CIR E;  5DMJ A;  2X10 A;  4M4R A;  3TJE F;  3ALQ R;  4MXW R;  3ME4 A;  4YN0 A;  2UWI A;  3U3V A;  5L36 B;  1SG1 X;  3THM F;  3QD6 R;  3MBW A;  4J6G C;  4BK5 A;  3URF Z;  4OD2 S;  4I9X C;  4BK4 A;  1NCF A; 
#chains in the Genus database with same CATH topology
 1D4V A;  3MHD D;  2E4W A;  3U3Q A;  2H9G R;  3MI8 D;  5BNQ R;  4M4P A;  4MSV B;  1FT4 A;  3WVT A;  3FL7 A;  2E4U A;  2LWL A;  3IJ2 X;  3QBQ B;  2E4V A;  2HEV R;  4GIQ R;  3X3F A;  1FD4 A;  2LXO A;  3BUK C;  2AW2 B;  4KGQ C;  3U3T A;  4N90 R;  3QO4 A;  5IHL A;  4FHQ A;  2MJK A;  4KGG C;  3U3P A;  2HEY R;  1ZA3 R;  1DU3 A;  3U3S A;  4RSU D;  1D0G R;  2E4X A;  3ME2 R;  1EXT A;  1JMA B;  4E4D R;  1TNR R;  3K51 B;  5CIR E;  5DMJ A;  2X10 A;  4M4R A;  3TJE F;  3ALQ R;  4MXW R;  3ME4 A;  4YN0 A;  2UWI A;  3U3V A;  2E4Y A;  5L36 B;  1SG1 X;  1FQQ A;  3THM F;  3QD6 R;  3MBW A;  4J6G C;  4BK5 A;  3URF Z;  2QR6 A;  4OD2 S;  1FD3 A;  1KJ6 A;  4I9X C;  4BK4 A;  1NCF A; 
#chains in the Genus database with same CATH homology
 1D4V A;  3MHD D;  3U3Q A;  2H9G R;  3MI8 D;  5BNQ R;  4M4P A;  4MSV B;  1FT4 A;  3WVT A;  3FL7 A;  2LWL A;  3IJ2 X;  3QBQ B;  2HEV R;  3X3F A;  4GIQ R;  1FD4 A;  2LXO A;  3BUK C;  2AW2 B;  4KGQ C;  3U3T A;  4N90 R;  3QO4 A;  5IHL A;  4FHQ A;  2MJK A;  4KGG C;  3U3P A;  2HEY R;  1ZA3 R;  1DU3 A;  3U3S A;  4RSU D;  1D0G R;  3ME2 R;  1EXT A;  1JMA B;  4E4D R;  1TNR R;  3K51 B;  5CIR E;  5DMJ A;  2X10 A;  4M4R A;  3TJE F;  3ALQ R;  4MXW R;  3ME4 A;  4YN0 A;  2UWI A;  3U3V A;  5L36 B;  1SG1 X;  1FQQ A;  3THM F;  3QD6 R;  3MBW A;  4J6G C;  4BK5 A;  3URF Z;  4OD2 S;  1FD3 A;  1KJ6 A;  4I9X C;  4BK4 A;  1NCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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