3SPDA

Crystal structure of aprataxin ortholog hnt3 in complex with dna
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
200
structure length
200
Chain Sequence
SFRDNLKVYIESPESYKNVIYYDDDVVLVRDMFPKSKMHLLLMTRDPHLTHVHPLEIMMKHRSLVEKLVSYVQGDLSGLIFDEARNCLSQQLTNEALANYIKVGFHAGPSMNNLHLHIMTLDHVSPSLKNSAHYISFTSPFFVKIDTPTSNLPTRGTLTSLFQEDLKCWRCGETFGRHFTKLKAHLQEEYDDWLDKSVSM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Schizosaccharomyces pombe
molecule keywords Aprataxin-like protein
total genus 65
structure length 200
sequence length 200
chains with identical sequence B, C, D
ec nomenclature ec 3.1.11.7: Adenosine-5'-diphospho-5'-(DNA) diphosphatase.
pdb deposition date 2011-07-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
A PF16278 zf-C2HE C2HE / C2H2 / C2HC zinc-binding finger
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 3spdA00
4ZKVA 5IPDA 1KPEA 3N1SA 4ZKLA 4EGUA 4YKLB 4QDEA 4EQEA 2Q4HA 6RHNA 6FITA 5CS2A 3FITA 5I2FA 3SZQA 2FITA 1KPAA 5IPBA 3L7XA 3TW2A 5ED6A 5FITA 4NK0A 1FITA 3R6FA 2Q4LA 1AV5A 3IMIA 3KSVA 5IPCA 1XMLA 1EMSA 4QEBA 3SPLA 1ST4A 4NJXA 5RHNA 4EQGA 3WO5A 4NDFA 3OMFA 3ANOA 4FITA 1Z84A 1KPCA 3RHNA 3N1TA 3OHEA 4XBAA 3O1XA 3OJ7A 2FHIA 5ED3A 4INCA 4INIA 3SPDA 1GUQA 1ZWJA 3BL9A 4QDVA 3P0TA 1XMMA 4NDHA 2H39A 3BLAA 5I2EA 3O1CA 5EMTA 4NDGA 4EQHA 5BV3A 3LB5A 3OXKA 1GUPA 1KPFA 3O1ZA 1HXQA 1HXPA 1KPBA 2EO4A 1FHIA 4NDIA 3I4SA 3QGZA 5IN3A 1VLRA 4NJYA 2OIKA 3BL7A 4NJZA 1RZYA 1ST0A 3I24A 4ZGLA 3NRDA 3O0MA 4RHNA 3SP4A 1Y23A 5IPEA
chains in the Genus database with same CATH superfamily
4ZKVA 5IPDA 1KPEA 3N1SA 4ZKLA 4EGUA 4YKLB 4QDEA 4EQEA 2Q4HA 6RHNA 6FITA 5CS2A 2R7PA 3FITA 5I2FA 3SZQA 2FITA 2R7CA 1KPAA 4I5TA 5IPBA 3L7XA 4I5VA 4G0AA 3TW2A 5ED6A 5FITA 4NK0A 1FITA 3R6FA 2Q4LA 2R8FA 1AV5A 3IMIA 3KSVA 5IPCA 1XMLA 1EMSA 4QEBA 3SPLA 4I5WA 1ST4A 4NJXA 5RHNA 4EQGA 2GU0A 3WO5A 4NDFA 3OMFA 3ANOA 4FITA 1Z84A 1KPCA 3RHNA 3N1TA 3OHEA 4XBAA 3O1XA 3OJ7A 2FHIA 5ED3A 4INCA 4INIA 3SPDA 1GUQA 1ZWJA 3BL9A 2LJWA 4QDVA 3P0TA 1XMMA 4NDHA 2H39A 3BLAA 5I2EA 3O1CA 1L9VA 4G0JA 5EMTA 4NDGA 4EQHA 5BV3A 3LB5A 3OXKA 1GUPA 1KPFA 3O1ZA 1HXQA 1HXPA 1KPBA 2EO4A 1FHIA 4NDIA 2R7JA 3I4SA 3QGZA 2POFA 5IN3A 1VLRA 4NJYA 2OIKA 3BL7A 4NJZA 1RZYA 1ST0A 3I24A 4ZGLA 3NRDA 3O0MA 4RHNA 3SP4A 1Y23A 5IPEA
chains in the Genus database with same CATH topology
4ZKVA 5IPDA 1KPEA 3N1SA 4ZKLA 4EGUA 4YKLB 4QDEA 4EQEA 2Q4HA 6RHNA 6FITA 5CS2A 3FITA 5I2FA 3SZQA 2FITA 1KPAA 5IPBA 3L7XA 3TW2A 5ED6A 5FITA 4NK0A 1FITA 3R6FA 2Q4LA 1AV5A 3IMIA 3KSVA 5IPCA 1XMLA 1EMSA 4QEBA 3SPLA 1ST4A 4NJXA 5RHNA 4EQGA 3WO5A 4NDFA 3OMFA 3ANOA 4FITA 1Z84A 1KPCA 3RHNA 3N1TA 3OHEA 4XBAA 3O1XA 3OJ7A 2FHIA 5ED3A 4INCA 4INIA 3SPDA 1GUQA 1ZWJA 3BL9A 4QDVA 3P0TA 1XMMA 4NDHA 2H39A 3BLAA 5I2EA 3O1CA 5EMTA 4NDGA 4EQHA 5BV3A 3LB5A 3OXKA 1GUPA 1KPFA 3O1ZA 1HXQA 1HXPA 1KPBA 2EO4A 1FHIA 4NDIA 3I4SA 3QGZA 5IN3A 1VLRA 4NJYA 2OIKA 3BL7A 4NJZA 1RZYA 1ST0A 3I24A 4ZGLA 3NRDA 3O0MA 4RHNA 3SP4A 1Y23A 5IPEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZKV A;  5IPD A;  1KPE A;  3N1S A;  4ZKL A;  4EGU A;  4YKL B;  4QDE A;  4EQE A;  2Q4H A;  6RHN A;  6FIT A;  5CS2 A;  3FIT A;  5I2F A;  3SZQ A;  2FIT A;  1KPA A;  5IPB A;  3L7X A;  3TW2 A;  5ED6 A;  5FIT A;  4NK0 A;  1FIT A;  3R6F A;  2Q4L A;  1AV5 A;  3IMI A;  3KSV A;  5IPC A;  1XML A;  1EMS A;  4QEB A;  3SPL A;  1ST4 A;  4NJX A;  5RHN A;  4EQG A;  3WO5 A;  4NDF A;  3OMF A;  3ANO A;  4FIT A;  1Z84 A;  1KPC A;  3RHN A;  3N1T A;  3OHE A;  4XBA A;  3O1X A;  3OJ7 A;  2FHI A;  5ED3 A;  4INC A;  4INI A;  3SPD A;  1GUQ A;  1ZWJ A;  3BL9 A;  4QDV A;  3P0T A;  1XMM A;  4NDH A;  2H39 A;  3BLA A;  5I2E A;  3O1C A;  5EMT A;  4NDG A;  4EQH A;  5BV3 A;  3LB5 A;  3OXK A;  1GUP A;  1KPF A;  3O1Z A;  1HXQ A;  1HXP A;  1KPB A;  2EO4 A;  1FHI A;  4NDI A;  3I4S A;  3QGZ A;  5IN3 A;  1VLR A;  4NJY A;  2OIK A;  3BL7 A;  4NJZ A;  1RZY A;  1ST0 A;  3I24 A;  4ZGL A;  3NRD A;  3O0M A;  4RHN A;  3SP4 A;  1Y23 A;  5IPE A; 
#chains in the Genus database with same CATH topology
 4ZKV A;  5IPD A;  1KPE A;  3N1S A;  4ZKL A;  4EGU A;  4YKL B;  4QDE A;  4EQE A;  2Q4H A;  6RHN A;  6FIT A;  5CS2 A;  2R7P A;  3FIT A;  5I2F A;  3SZQ A;  2FIT A;  2R7C A;  1KPA A;  4I5T A;  5IPB A;  3L7X A;  4I5V A;  4G0A A;  3TW2 A;  5ED6 A;  5FIT A;  4NK0 A;  1FIT A;  3R6F A;  2Q4L A;  2R8F A;  1AV5 A;  3IMI A;  3KSV A;  5IPC A;  1XML A;  1EMS A;  4QEB A;  3SPL A;  4I5W A;  1ST4 A;  4NJX A;  5RHN A;  4EQG A;  2GU0 A;  3WO5 A;  4NDF A;  3OMF A;  3ANO A;  4FIT A;  1Z84 A;  1KPC A;  3RHN A;  3N1T A;  3OHE A;  4XBA A;  3O1X A;  3OJ7 A;  2FHI A;  5ED3 A;  4INC A;  4INI A;  3SPD A;  1GUQ A;  1ZWJ A;  3BL9 A;  2LJW A;  4QDV A;  3P0T A;  1XMM A;  4NDH A;  2H39 A;  3BLA A;  5I2E A;  3O1C A;  1L9V A;  4G0J A;  5EMT A;  4NDG A;  4EQH A;  5BV3 A;  3LB5 A;  3OXK A;  1GUP A;  1KPF A;  3O1Z A;  1HXQ A;  1HXP A;  1KPB A;  2EO4 A;  1FHI A;  4NDI A;  2R7J A;  3I4S A;  3QGZ A;  2POF A;  5IN3 A;  1VLR A;  4NJY A;  2OIK A;  3BL7 A;  4NJZ A;  1RZY A;  1ST0 A;  3I24 A;  4ZGL A;  3NRD A;  3O0M A;  4RHN A;  3SP4 A;  1Y23 A;  5IPE A; 
#chains in the Genus database with same CATH homology
 4ZKV A;  5IPD A;  1KPE A;  3N1S A;  4ZKL A;  4EGU A;  4YKL B;  4QDE A;  4EQE A;  2Q4H A;  6RHN A;  6FIT A;  5CS2 A;  3FIT A;  5I2F A;  3SZQ A;  2FIT A;  1KPA A;  5IPB A;  3L7X A;  3TW2 A;  5ED6 A;  5FIT A;  4NK0 A;  1FIT A;  3R6F A;  2Q4L A;  1AV5 A;  3IMI A;  3KSV A;  5IPC A;  1XML A;  1EMS A;  4QEB A;  3SPL A;  1ST4 A;  4NJX A;  5RHN A;  4EQG A;  3WO5 A;  4NDF A;  3OMF A;  3ANO A;  4FIT A;  1Z84 A;  1KPC A;  3RHN A;  3N1T A;  3OHE A;  4XBA A;  3O1X A;  3OJ7 A;  2FHI A;  5ED3 A;  4INC A;  4INI A;  3SPD A;  1GUQ A;  1ZWJ A;  3BL9 A;  4QDV A;  3P0T A;  1XMM A;  4NDH A;  2H39 A;  3BLA A;  5I2E A;  3O1C A;  5EMT A;  4NDG A;  4EQH A;  5BV3 A;  3LB5 A;  3OXK A;  1GUP A;  1KPF A;  3O1Z A;  1HXQ A;  1HXP A;  1KPB A;  2EO4 A;  1FHI A;  4NDI A;  3I4S A;  3QGZ A;  5IN3 A;  1VLR A;  4NJY A;  2OIK A;  3BL7 A;  4NJZ A;  1RZY A;  1ST0 A;  3I24 A;  4ZGL A;  3NRD A;  3O0M A;  4RHN A;  3SP4 A;  1Y23 A;  5IPE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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