4EQEA

Crystal structure of histidine triad nucleotide-binding protein 1 (hint1) from human complexed with lys-ams
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
114
structure length
113
Chain Sequence
PGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHHLHVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 30
structure length 113
sequence length 114
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2012-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 4eqeA00
3BLAA 4QDVA 1FITA 1VLRA 3I4SA 5FITA 3SPDA 4ZKLA 1ZWJA 5ED3A 3NRDA 2EO4A 5EMTA 3N1SA 1XMMA 4NJZA 4NDFA 2Q4LA 4NDIA 4INIA 4EQHA 6RHNA 4EQGA 2FITA 1HXPA 3P0TA 5RHNA 5ED6A 3IMIA 1KPFA 3L7XA 4NDGA 1KPBA 4XBAA 3OMFA 3O1XA 3BL9A 1Y23A 4EGUA 5IPDA 5IN3A 4EQEA 3KSVA 4RHNA 1GUPA 4NJXA 3RHNA 3SZQA 1XMLA 5I2EA 5I2FA 5IPBA 4NDHA 3ANOA 1RZYA 4QEBA 6FITA 1GUQA 4YKLB 3O1ZA 2OIKA 1AV5A 1ST0A 1Z84A 1EMSA 5IPCA 1KPAA 2H39A 3TW2A 4NK0A 1FHIA 3OJ7A 1KPEA 3FITA 1KPCA 3O1CA 5IPEA 2FHIA 3OXKA 3QGZA 5BV3A 2Q4HA 3R6FA 3SPLA 1HXQA 4NJYA 4ZKVA 3I24A 5CS2A 3N1TA 4INCA 3BL7A 4ZGLA 3OHEA 3WO5A 4QDEA 3LB5A 1ST4A 3O0MA 4FITA 3SP4A
chains in the Genus database with same CATH superfamily
3BLAA 4QDVA 1FITA 1VLRA 3I4SA 5FITA 3SPDA 4ZKLA 4I5TA 1ZWJA 5ED3A 3NRDA 2EO4A 5EMTA 3N1SA 2R7CA 4G0JA 2R7PA 1XMMA 4NJZA 4NDFA 2Q4LA 4NDIA 4INIA 4EQHA 6RHNA 4EQGA 2FITA 1HXPA 3P0TA 5RHNA 4I5VA 2GU0A 3IMIA 1KPFA 5ED6A 3L7XA 4NDGA 1KPBA 4XBAA 3OMFA 3O1XA 3BL9A 1Y23A 4EGUA 5IPDA 5IN3A 4EQEA 3KSVA 4RHNA 1GUPA 4NJXA 4G0AA 2R7JA 3RHNA 3SZQA 1XMLA 5I2EA 5I2FA 5IPBA 2LJWA 4NDHA 3ANOA 1RZYA 4QEBA 6FITA 1GUQA 4YKLB 3O1ZA 2OIKA 1AV5A 1ST0A 1Z84A 1EMSA 5IPCA 1KPAA 2H39A 3TW2A 4NK0A 1FHIA 3OJ7A 1KPEA 4I5WA 3FITA 1KPCA 3O1CA 5IPEA 2FHIA 2R8FA 3OXKA 3QGZA 5BV3A 2Q4HA 3R6FA 3SPLA 1HXQA 4NJYA 4ZKVA 3I24A 5CS2A 3N1TA 1L9VA 4INCA 3BL7A 4ZGLA 3OHEA 3WO5A 4QDEA 3LB5A 1ST4A 3O0MA 4FITA 2POFA 3SP4A
chains in the Genus database with same CATH topology
3BLAA 4QDVA 1FITA 1VLRA 3I4SA 5FITA 3SPDA 4ZKLA 1ZWJA 5ED3A 3NRDA 2EO4A 5EMTA 3N1SA 1XMMA 4NJZA 4NDFA 2Q4LA 4NDIA 4INIA 4EQHA 6RHNA 4EQGA 2FITA 1HXPA 3P0TA 5RHNA 5ED6A 3IMIA 1KPFA 3L7XA 4NDGA 1KPBA 4XBAA 3OMFA 3O1XA 3BL9A 1Y23A 4EGUA 5IPDA 5IN3A 4EQEA 3KSVA 4RHNA 1GUPA 4NJXA 3RHNA 3SZQA 1XMLA 5I2EA 5I2FA 5IPBA 4NDHA 3ANOA 1RZYA 4QEBA 6FITA 1GUQA 4YKLB 3O1ZA 2OIKA 1AV5A 1ST0A 1Z84A 1EMSA 5IPCA 1KPAA 2H39A 3TW2A 4NK0A 1FHIA 3OJ7A 1KPEA 3FITA 1KPCA 3O1CA 5IPEA 2FHIA 3OXKA 3QGZA 5BV3A 2Q4HA 3R6FA 3SPLA 1HXQA 4NJYA 4ZKVA 3I24A 5CS2A 3N1TA 4INCA 3BL7A 4ZGLA 3OHEA 3WO5A 4QDEA 3LB5A 1ST4A 3O0MA 4FITA 3SP4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BLA A;  4QDV A;  1FIT A;  1VLR A;  3I4S A;  5FIT A;  3SPD A;  4ZKL A;  1ZWJ A;  5ED3 A;  3NRD A;  2EO4 A;  5EMT A;  3N1S A;  1XMM A;  4NJZ A;  4NDF A;  2Q4L A;  4NDI A;  4INI A;  4EQH A;  6RHN A;  4EQG A;  2FIT A;  1HXP A;  3P0T A;  5RHN A;  5ED6 A;  3IMI A;  1KPF A;  3L7X A;  4NDG A;  1KPB A;  4XBA A;  3OMF A;  3O1X A;  3BL9 A;  1Y23 A;  4EGU A;  5IPD A;  5IN3 A;  4EQE A;  3KSV A;  4RHN A;  1GUP A;  4NJX A;  3RHN A;  3SZQ A;  1XML A;  5I2E A;  5I2F A;  5IPB A;  4NDH A;  3ANO A;  1RZY A;  4QEB A;  6FIT A;  1GUQ A;  4YKL B;  3O1Z A;  2OIK A;  1AV5 A;  1ST0 A;  1Z84 A;  1EMS A;  5IPC A;  1KPA A;  2H39 A;  3TW2 A;  4NK0 A;  1FHI A;  3OJ7 A;  1KPE A;  3FIT A;  1KPC A;  3O1C A;  5IPE A;  2FHI A;  3OXK A;  3QGZ A;  5BV3 A;  2Q4H A;  3R6F A;  3SPL A;  1HXQ A;  4NJY A;  4ZKV A;  3I24 A;  5CS2 A;  3N1T A;  4INC A;  3BL7 A;  4ZGL A;  3OHE A;  3WO5 A;  4QDE A;  3LB5 A;  1ST4 A;  3O0M A;  4FIT A;  3SP4 A; 
#chains in the Genus database with same CATH topology
 3BLA A;  4QDV A;  1FIT A;  1VLR A;  3I4S A;  5FIT A;  3SPD A;  4ZKL A;  4I5T A;  1ZWJ A;  5ED3 A;  3NRD A;  2EO4 A;  5EMT A;  3N1S A;  2R7C A;  4G0J A;  2R7P A;  1XMM A;  4NJZ A;  4NDF A;  2Q4L A;  4NDI A;  4INI A;  4EQH A;  6RHN A;  4EQG A;  2FIT A;  1HXP A;  3P0T A;  5RHN A;  4I5V A;  2GU0 A;  3IMI A;  1KPF A;  5ED6 A;  3L7X A;  4NDG A;  1KPB A;  4XBA A;  3OMF A;  3O1X A;  3BL9 A;  1Y23 A;  4EGU A;  5IPD A;  5IN3 A;  4EQE A;  3KSV A;  4RHN A;  1GUP A;  4NJX A;  4G0A A;  2R7J A;  3RHN A;  3SZQ A;  1XML A;  5I2E A;  5I2F A;  5IPB A;  2LJW A;  4NDH A;  3ANO A;  1RZY A;  4QEB A;  6FIT A;  1GUQ A;  4YKL B;  3O1Z A;  2OIK A;  1AV5 A;  1ST0 A;  1Z84 A;  1EMS A;  5IPC A;  1KPA A;  2H39 A;  3TW2 A;  4NK0 A;  1FHI A;  3OJ7 A;  1KPE A;  4I5W A;  3FIT A;  1KPC A;  3O1C A;  5IPE A;  2FHI A;  2R8F A;  3OXK A;  3QGZ A;  5BV3 A;  2Q4H A;  3R6F A;  3SPL A;  1HXQ A;  4NJY A;  4ZKV A;  3I24 A;  5CS2 A;  3N1T A;  1L9V A;  4INC A;  3BL7 A;  4ZGL A;  3OHE A;  3WO5 A;  4QDE A;  3LB5 A;  1ST4 A;  3O0M A;  4FIT A;  2POF A;  3SP4 A; 
#chains in the Genus database with same CATH homology
 3BLA A;  4QDV A;  1FIT A;  1VLR A;  3I4S A;  5FIT A;  3SPD A;  4ZKL A;  1ZWJ A;  5ED3 A;  3NRD A;  2EO4 A;  5EMT A;  3N1S A;  1XMM A;  4NJZ A;  4NDF A;  2Q4L A;  4NDI A;  4INI A;  4EQH A;  6RHN A;  4EQG A;  2FIT A;  1HXP A;  3P0T A;  5RHN A;  5ED6 A;  3IMI A;  1KPF A;  3L7X A;  4NDG A;  1KPB A;  4XBA A;  3OMF A;  3O1X A;  3BL9 A;  1Y23 A;  4EGU A;  5IPD A;  5IN3 A;  4EQE A;  3KSV A;  4RHN A;  1GUP A;  4NJX A;  3RHN A;  3SZQ A;  1XML A;  5I2E A;  5I2F A;  5IPB A;  4NDH A;  3ANO A;  1RZY A;  4QEB A;  6FIT A;  1GUQ A;  4YKL B;  3O1Z A;  2OIK A;  1AV5 A;  1ST0 A;  1Z84 A;  1EMS A;  5IPC A;  1KPA A;  2H39 A;  3TW2 A;  4NK0 A;  1FHI A;  3OJ7 A;  1KPE A;  3FIT A;  1KPC A;  3O1C A;  5IPE A;  2FHI A;  3OXK A;  3QGZ A;  5BV3 A;  2Q4H A;  3R6F A;  3SPL A;  1HXQ A;  4NJY A;  4ZKV A;  3I24 A;  5CS2 A;  3N1T A;  4INC A;  3BL7 A;  4ZGL A;  3OHE A;  3WO5 A;  4QDE A;  3LB5 A;  1ST4 A;  3O0M A;  4FIT A;  3SP4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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