4EQGA

Crystal structure of histidine triad nucleotide-binding protein 1 (hint1) from human complexed with ala-ams
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
114
structure length
114
Chain Sequence
PGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 30
structure length 114
sequence length 114
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2012-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 4eqgA00
4QEBA 2OIKA 4INCA 3SPDA 5FITA 4EQHA 1ST4A 4FITA 5IPEA 3O1XA 5CS2A 1ST0A 2H39A 1AV5A 4EQEA 2Q4HA 4NK0A 3O1ZA 1XMLA 1EMSA 1GUQA 3P0TA 3NRDA 3O0MA 1FITA 2FITA 4EQGA 3RHNA 2FHIA 4YKLB 3I4SA 1KPAA 3L7XA 4INIA 5RHNA 3OHEA 4NDIA 3OMFA 1VLRA 1ZWJA 4EGUA 5IN3A 1KPFA 6FITA 1XMMA 3TW2A 3BL7A 3N1TA 2Q4LA 3SP4A 5I2EA 4NDGA 3N1SA 3FITA 1FHIA 3LB5A 4ZKLA 4NJZA 3BL9A 4XBAA 1HXPA 2EO4A 4QDVA 3BLAA 1KPBA 4NDHA 1Y23A 5IPBA 3WO5A 5BV3A 3OJ7A 4ZGLA 3I24A 3O1CA 5EMTA 3R6FA 3OXKA 4NJXA 4RHNA 4ZKVA 4NDFA 1KPCA 6RHNA 3SZQA 4QDEA 5ED6A 5IPDA 5ED3A 1Z84A 1GUPA 3KSVA 3ANOA 4NJYA 1HXQA 1KPEA 3SPLA 5I2FA 5IPCA 1RZYA 3IMIA 3QGZA
chains in the Genus database with same CATH superfamily
4QEBA 2OIKA 2R7JA 2R7CA 4INCA 3SPDA 5FITA 4EQHA 1ST4A 4FITA 5IPEA 3O1XA 5CS2A 1ST0A 4I5TA 2H39A 1AV5A 4EQEA 2Q4HA 4NK0A 3O1ZA 1XMLA 1EMSA 4G0AA 1GUQA 3P0TA 3NRDA 3O0MA 1FITA 2FITA 4EQGA 3RHNA 2FHIA 4YKLB 3I4SA 1KPAA 3L7XA 4INIA 5RHNA 3OHEA 4NDIA 3OMFA 1VLRA 1ZWJA 4EGUA 5IN3A 1KPFA 6FITA 1L9VA 2LJWA 1XMMA 3TW2A 3BL7A 3N1TA 2Q4LA 2POFA 4I5WA 3SP4A 5I2EA 4NDGA 2GU0A 3N1SA 3FITA 1FHIA 3LB5A 4ZKLA 4NJZA 3BL9A 4XBAA 1HXPA 2EO4A 4I5VA 2R8FA 4QDVA 4G0JA 3BLAA 1KPBA 4NDHA 1Y23A 5IPBA 3WO5A 5BV3A 3OJ7A 4ZGLA 3I24A 3O1CA 5EMTA 3R6FA 2R7PA 3OXKA 4NJXA 4RHNA 4ZKVA 4NDFA 1KPCA 6RHNA 3SZQA 4QDEA 5ED6A 5IPDA 5ED3A 1Z84A 1GUPA 3KSVA 3ANOA 4NJYA 1HXQA 1KPEA 3SPLA 5I2FA 5IPCA 1RZYA 3IMIA 3QGZA
chains in the Genus database with same CATH topology
4QEBA 2OIKA 4INCA 3SPDA 5FITA 4EQHA 1ST4A 4FITA 5IPEA 3O1XA 5CS2A 1ST0A 2H39A 1AV5A 4EQEA 2Q4HA 4NK0A 3O1ZA 1XMLA 1EMSA 1GUQA 3P0TA 3NRDA 3O0MA 1FITA 2FITA 4EQGA 3RHNA 2FHIA 4YKLB 3I4SA 1KPAA 3L7XA 4INIA 5RHNA 3OHEA 4NDIA 3OMFA 1VLRA 1ZWJA 4EGUA 5IN3A 1KPFA 6FITA 1XMMA 3TW2A 3BL7A 3N1TA 2Q4LA 3SP4A 5I2EA 4NDGA 3N1SA 3FITA 1FHIA 3LB5A 4ZKLA 4NJZA 3BL9A 4XBAA 1HXPA 2EO4A 4QDVA 3BLAA 1KPBA 4NDHA 1Y23A 5IPBA 3WO5A 5BV3A 3OJ7A 4ZGLA 3I24A 3O1CA 5EMTA 3R6FA 3OXKA 4NJXA 4RHNA 4ZKVA 4NDFA 1KPCA 6RHNA 3SZQA 4QDEA 5ED6A 5IPDA 5ED3A 1Z84A 1GUPA 3KSVA 3ANOA 4NJYA 1HXQA 1KPEA 3SPLA 5I2FA 5IPCA 1RZYA 3IMIA 3QGZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QEB A;  2OIK A;  4INC A;  3SPD A;  5FIT A;  4EQH A;  1ST4 A;  4FIT A;  5IPE A;  3O1X A;  5CS2 A;  1ST0 A;  2H39 A;  1AV5 A;  4EQE A;  2Q4H A;  4NK0 A;  3O1Z A;  1XML A;  1EMS A;  1GUQ A;  3P0T A;  3NRD A;  3O0M A;  1FIT A;  2FIT A;  4EQG A;  3RHN A;  2FHI A;  4YKL B;  3I4S A;  1KPA A;  3L7X A;  4INI A;  5RHN A;  3OHE A;  4NDI A;  3OMF A;  1VLR A;  1ZWJ A;  4EGU A;  5IN3 A;  1KPF A;  6FIT A;  1XMM A;  3TW2 A;  3BL7 A;  3N1T A;  2Q4L A;  3SP4 A;  5I2E A;  4NDG A;  3N1S A;  3FIT A;  1FHI A;  3LB5 A;  4ZKL A;  4NJZ A;  3BL9 A;  4XBA A;  1HXP A;  2EO4 A;  4QDV A;  3BLA A;  1KPB A;  4NDH A;  1Y23 A;  5IPB A;  3WO5 A;  5BV3 A;  3OJ7 A;  4ZGL A;  3I24 A;  3O1C A;  5EMT A;  3R6F A;  3OXK A;  4NJX A;  4RHN A;  4ZKV A;  4NDF A;  1KPC A;  6RHN A;  3SZQ A;  4QDE A;  5ED6 A;  5IPD A;  5ED3 A;  1Z84 A;  1GUP A;  3KSV A;  3ANO A;  4NJY A;  1HXQ A;  1KPE A;  3SPL A;  5I2F A;  5IPC A;  1RZY A;  3IMI A;  3QGZ A; 
#chains in the Genus database with same CATH topology
 4QEB A;  2OIK A;  2R7J A;  2R7C A;  4INC A;  3SPD A;  5FIT A;  4EQH A;  1ST4 A;  4FIT A;  5IPE A;  3O1X A;  5CS2 A;  1ST0 A;  4I5T A;  2H39 A;  1AV5 A;  4EQE A;  2Q4H A;  4NK0 A;  3O1Z A;  1XML A;  1EMS A;  4G0A A;  1GUQ A;  3P0T A;  3NRD A;  3O0M A;  1FIT A;  2FIT A;  4EQG A;  3RHN A;  2FHI A;  4YKL B;  3I4S A;  1KPA A;  3L7X A;  4INI A;  5RHN A;  3OHE A;  4NDI A;  3OMF A;  1VLR A;  1ZWJ A;  4EGU A;  5IN3 A;  1KPF A;  6FIT A;  1L9V A;  2LJW A;  1XMM A;  3TW2 A;  3BL7 A;  3N1T A;  2Q4L A;  2POF A;  4I5W A;  3SP4 A;  5I2E A;  4NDG A;  2GU0 A;  3N1S A;  3FIT A;  1FHI A;  3LB5 A;  4ZKL A;  4NJZ A;  3BL9 A;  4XBA A;  1HXP A;  2EO4 A;  4I5V A;  2R8F A;  4QDV A;  4G0J A;  3BLA A;  1KPB A;  4NDH A;  1Y23 A;  5IPB A;  3WO5 A;  5BV3 A;  3OJ7 A;  4ZGL A;  3I24 A;  3O1C A;  5EMT A;  3R6F A;  2R7P A;  3OXK A;  4NJX A;  4RHN A;  4ZKV A;  4NDF A;  1KPC A;  6RHN A;  3SZQ A;  4QDE A;  5ED6 A;  5IPD A;  5ED3 A;  1Z84 A;  1GUP A;  3KSV A;  3ANO A;  4NJY A;  1HXQ A;  1KPE A;  3SPL A;  5I2F A;  5IPC A;  1RZY A;  3IMI A;  3QGZ A; 
#chains in the Genus database with same CATH homology
 4QEB A;  2OIK A;  4INC A;  3SPD A;  5FIT A;  4EQH A;  1ST4 A;  4FIT A;  5IPE A;  3O1X A;  5CS2 A;  1ST0 A;  2H39 A;  1AV5 A;  4EQE A;  2Q4H A;  4NK0 A;  3O1Z A;  1XML A;  1EMS A;  1GUQ A;  3P0T A;  3NRD A;  3O0M A;  1FIT A;  2FIT A;  4EQG A;  3RHN A;  2FHI A;  4YKL B;  3I4S A;  1KPA A;  3L7X A;  4INI A;  5RHN A;  3OHE A;  4NDI A;  3OMF A;  1VLR A;  1ZWJ A;  4EGU A;  5IN3 A;  1KPF A;  6FIT A;  1XMM A;  3TW2 A;  3BL7 A;  3N1T A;  2Q4L A;  3SP4 A;  5I2E A;  4NDG A;  3N1S A;  3FIT A;  1FHI A;  3LB5 A;  4ZKL A;  4NJZ A;  3BL9 A;  4XBA A;  1HXP A;  2EO4 A;  4QDV A;  3BLA A;  1KPB A;  4NDH A;  1Y23 A;  5IPB A;  3WO5 A;  5BV3 A;  3OJ7 A;  4ZGL A;  3I24 A;  3O1C A;  5EMT A;  3R6F A;  3OXK A;  4NJX A;  4RHN A;  4ZKV A;  4NDF A;  1KPC A;  6RHN A;  3SZQ A;  4QDE A;  5ED6 A;  5IPD A;  5ED3 A;  1Z84 A;  1GUP A;  3KSV A;  3ANO A;  4NJY A;  1HXQ A;  1KPE A;  3SPL A;  5I2F A;  5IPC A;  1RZY A;  3IMI A;  3QGZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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