4EQGA

Crystal structure of histidine triad nucleotide-binding protein 1 (hint1) from human complexed with ala-ams
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
114
structure length
114
Chain Sequence
PGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
pubmed doi rcsb
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 30
structure length 114
sequence length 114
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2012-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 4eqgA00
3I24A 3OMFA 3O1XA 3OHEA 3ANOA 3BLAA 3I4SA 3OXKA 2H39A 5FITA 4ZKVA 4NDFA 5EMTA 3RHNA 3O0MA 5IPDA 2EO4A 5ED3A 4EQEA 6RHNA 4YKLB 1KPBA 3BL9A 3R6FA 4NJYA 4QDEA 3KSVA 4NDHA 4RHNA 5I2FA 4ZKLA 1Z84A 3O1CA 4NJZA 1HXPA 3SZQA 4QEBA 1EMSA 3L7XA 5I2EA 3FITA 1KPCA 3N1SA 5ED6A 3N1TA 1HXQA 6FITA 4EGUA 4QDVA 1ZWJA 1ST4A 5CS2A 5RHNA 1KPAA 5IPCA 3OJ7A 4EQHA 3QGZA 4ZGLA 1XMLA 1VLRA 3WO5A 2Q4LA 3BL7A 4INCA 4NK0A 5IPEA 4NDIA 1FITA 3LB5A 4EQGA 1XMMA 4NJXA 5IN3A 1RZYA 4NDGA 1Y23A 3P0TA 1KPEA 4INIA 4XBAA 1ST0A 1KPFA 2Q4HA 2FITA 3NRDA 1GUQA 4FITA 3TW2A 2FHIA 2OIKA 1GUPA 3IMIA 3O1ZA 5IPBA 3SP4A 1FHIA 1AV5A 5BV3A 3SPDA 3SPLA
chains in the Genus database with same CATH superfamily
2R8FA 3I24A 1L9VA 3O1XA 3OHEA 3ANOA 3BLAA 3OMFA 3I4SA 3OXKA 2H39A 5FITA 4ZKVA 2R7PA 4I5WA 4NDFA 5EMTA 3RHNA 3O0MA 5IPDA 2EO4A 2R7JA 5ED3A 4EQEA 6RHNA 4YKLB 1KPBA 3BL9A 3R6FA 4NJYA 4I5TA 4QDEA 3KSVA 4NDHA 4RHNA 5I2FA 4ZKLA 1Z84A 3O1CA 4NJZA 1HXPA 3SZQA 4QEBA 1EMSA 3L7XA 5I2EA 3FITA 1KPCA 3N1SA 5ED6A 3N1TA 1HXQA 6FITA 4EGUA 4QDVA 2R7CA 1ZWJA 1ST4A 5CS2A 5RHNA 1KPAA 5IPCA 4G0AA 3OJ7A 4EQHA 3QGZA 4ZGLA 1XMLA 1VLRA 3WO5A 2Q4LA 3BL7A 4INCA 4NK0A 5IPEA 2GU0A 4NDIA 1FITA 3LB5A 4EQGA 1XMMA 4I5VA 4NJXA 5IN3A 1RZYA 4NDGA 1Y23A 3P0TA 1KPEA 4INIA 2POFA 4XBAA 1ST0A 1KPFA 2Q4HA 2FITA 3NRDA 1GUQA 4FITA 3TW2A 2FHIA 4G0JA 2OIKA 1GUPA 3IMIA 3O1ZA 5IPBA 3SP4A 1FHIA 1AV5A 2LJWA 5BV3A 3SPDA 3SPLA
chains in the Genus database with same CATH topology
3I24A 3OMFA 3O1XA 3OHEA 3ANOA 3BLAA 3I4SA 3OXKA 2H39A 5FITA 4ZKVA 4NDFA 5EMTA 3RHNA 3O0MA 5IPDA 2EO4A 5ED3A 4EQEA 6RHNA 4YKLB 1KPBA 3BL9A 3R6FA 4NJYA 4QDEA 3KSVA 4NDHA 4RHNA 5I2FA 4ZKLA 1Z84A 3O1CA 4NJZA 1HXPA 3SZQA 4QEBA 1EMSA 3L7XA 5I2EA 3FITA 1KPCA 3N1SA 5ED6A 3N1TA 1HXQA 6FITA 4EGUA 4QDVA 1ZWJA 1ST4A 5CS2A 5RHNA 1KPAA 5IPCA 3OJ7A 4EQHA 3QGZA 4ZGLA 1XMLA 1VLRA 3WO5A 2Q4LA 3BL7A 4INCA 4NK0A 5IPEA 4NDIA 1FITA 3LB5A 4EQGA 1XMMA 4NJXA 5IN3A 1RZYA 4NDGA 1Y23A 3P0TA 1KPEA 4INIA 4XBAA 1ST0A 1KPFA 2Q4HA 2FITA 3NRDA 1GUQA 4FITA 3TW2A 2FHIA 2OIKA 1GUPA 3IMIA 3O1ZA 5IPBA 3SP4A 1FHIA 1AV5A 5BV3A 3SPDA 3SPLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I24 A;  3OMF A;  3O1X A;  3OHE A;  3ANO A;  3BLA A;  3I4S A;  3OXK A;  2H39 A;  5FIT A;  4ZKV A;  4NDF A;  5EMT A;  3RHN A;  3O0M A;  5IPD A;  2EO4 A;  5ED3 A;  4EQE A;  6RHN A;  4YKL B;  1KPB A;  3BL9 A;  3R6F A;  4NJY A;  4QDE A;  3KSV A;  4NDH A;  4RHN A;  5I2F A;  4ZKL A;  1Z84 A;  3O1C A;  4NJZ A;  1HXP A;  3SZQ A;  4QEB A;  1EMS A;  3L7X A;  5I2E A;  3FIT A;  1KPC A;  3N1S A;  5ED6 A;  3N1T A;  1HXQ A;  6FIT A;  4EGU A;  4QDV A;  1ZWJ A;  1ST4 A;  5CS2 A;  5RHN A;  1KPA A;  5IPC A;  3OJ7 A;  4EQH A;  3QGZ A;  4ZGL A;  1XML A;  1VLR A;  3WO5 A;  2Q4L A;  3BL7 A;  4INC A;  4NK0 A;  5IPE A;  4NDI A;  1FIT A;  3LB5 A;  4EQG A;  1XMM A;  4NJX A;  5IN3 A;  1RZY A;  4NDG A;  1Y23 A;  3P0T A;  1KPE A;  4INI A;  4XBA A;  1ST0 A;  1KPF A;  2Q4H A;  2FIT A;  3NRD A;  1GUQ A;  4FIT A;  3TW2 A;  2FHI A;  2OIK A;  1GUP A;  3IMI A;  3O1Z A;  5IPB A;  3SP4 A;  1FHI A;  1AV5 A;  5BV3 A;  3SPD A;  3SPL A; 
#chains in the Genus database with same CATH topology
 2R8F A;  3I24 A;  1L9V A;  3O1X A;  3OHE A;  3ANO A;  3BLA A;  3OMF A;  3I4S A;  3OXK A;  2H39 A;  5FIT A;  4ZKV A;  2R7P A;  4I5W A;  4NDF A;  5EMT A;  3RHN A;  3O0M A;  5IPD A;  2EO4 A;  2R7J A;  5ED3 A;  4EQE A;  6RHN A;  4YKL B;  1KPB A;  3BL9 A;  3R6F A;  4NJY A;  4I5T A;  4QDE A;  3KSV A;  4NDH A;  4RHN A;  5I2F A;  4ZKL A;  1Z84 A;  3O1C A;  4NJZ A;  1HXP A;  3SZQ A;  4QEB A;  1EMS A;  3L7X A;  5I2E A;  3FIT A;  1KPC A;  3N1S A;  5ED6 A;  3N1T A;  1HXQ A;  6FIT A;  4EGU A;  4QDV A;  2R7C A;  1ZWJ A;  1ST4 A;  5CS2 A;  5RHN A;  1KPA A;  5IPC A;  4G0A A;  3OJ7 A;  4EQH A;  3QGZ A;  4ZGL A;  1XML A;  1VLR A;  3WO5 A;  2Q4L A;  3BL7 A;  4INC A;  4NK0 A;  5IPE A;  2GU0 A;  4NDI A;  1FIT A;  3LB5 A;  4EQG A;  1XMM A;  4I5V A;  4NJX A;  5IN3 A;  1RZY A;  4NDG A;  1Y23 A;  3P0T A;  1KPE A;  4INI A;  2POF A;  4XBA A;  1ST0 A;  1KPF A;  2Q4H A;  2FIT A;  3NRD A;  1GUQ A;  4FIT A;  3TW2 A;  2FHI A;  4G0J A;  2OIK A;  1GUP A;  3IMI A;  3O1Z A;  5IPB A;  3SP4 A;  1FHI A;  1AV5 A;  2LJW A;  5BV3 A;  3SPD A;  3SPL A; 
#chains in the Genus database with same CATH homology
 3I24 A;  3OMF A;  3O1X A;  3OHE A;  3ANO A;  3BLA A;  3I4S A;  3OXK A;  2H39 A;  5FIT A;  4ZKV A;  4NDF A;  5EMT A;  3RHN A;  3O0M A;  5IPD A;  2EO4 A;  5ED3 A;  4EQE A;  6RHN A;  4YKL B;  1KPB A;  3BL9 A;  3R6F A;  4NJY A;  4QDE A;  3KSV A;  4NDH A;  4RHN A;  5I2F A;  4ZKL A;  1Z84 A;  3O1C A;  4NJZ A;  1HXP A;  3SZQ A;  4QEB A;  1EMS A;  3L7X A;  5I2E A;  3FIT A;  1KPC A;  3N1S A;  5ED6 A;  3N1T A;  1HXQ A;  6FIT A;  4EGU A;  4QDV A;  1ZWJ A;  1ST4 A;  5CS2 A;  5RHN A;  1KPA A;  5IPC A;  3OJ7 A;  4EQH A;  3QGZ A;  4ZGL A;  1XML A;  1VLR A;  3WO5 A;  2Q4L A;  3BL7 A;  4INC A;  4NK0 A;  5IPE A;  4NDI A;  1FIT A;  3LB5 A;  4EQG A;  1XMM A;  4NJX A;  5IN3 A;  1RZY A;  4NDG A;  1Y23 A;  3P0T A;  1KPE A;  4INI A;  4XBA A;  1ST0 A;  1KPF A;  2Q4H A;  2FIT A;  3NRD A;  1GUQ A;  4FIT A;  3TW2 A;  2FHI A;  2OIK A;  1GUP A;  3IMI A;  3O1Z A;  5IPB A;  3SP4 A;  1FHI A;  1AV5 A;  5BV3 A;  3SPD A;  3SPL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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