4EQHA

Crystal structure of histidine triad nucleotide-binding protein 1 (hint1) from human complexed with trp-ams
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
114
structure length
114
Chain Sequence
PGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Side chain independent recognition of aminoacyl adenylates by the hint1 transcription suppressor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 29
structure length 114
sequence length 114
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2012-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 4eqhA00
3R6FA 3SZQA 3ANOA 3SP4A 4EQHA 4ZGLA 1KPFA 5I2FA 3O1XA 1FITA 1KPBA 3OHEA 4NJXA 4NDHA 3O1CA 3OJ7A 6FITA 4XBAA 1Z84A 3N1TA 1ZWJA 5I2EA 6RHNA 2H39A 5ED3A 5IPBA 5IPEA 3N1SA 1GUQA 3OMFA 4NDGA 4FITA 4QEBA 5IPCA 1FHIA 3I4SA 5EMTA 2FHIA 3BLAA 3O1ZA 3RHNA 4ZKVA 3BL7A 1KPCA 1Y23A 1HXPA 3OXKA 4QDVA 3TW2A 2EO4A 5IN3A 5FITA 4INIA 4RHNA 4YKLB 1ST0A 5IPDA 1VLRA 4EQEA 2FITA 3BL9A 5CS2A 2Q4HA 4NDFA 4QDEA 4NJZA 1KPAA 1AV5A 1ST4A 1XMMA 1EMSA 5ED6A 2OIKA 4INCA 3QGZA 3I24A 3FITA 3KSVA 4NJYA 3SPDA 5BV3A 3IMIA 4NK0A 5RHNA 3O0MA 3P0TA 4ZKLA 1HXQA 3SPLA 4EQGA 1RZYA 3WO5A 2Q4LA 3NRDA 4EGUA 1XMLA 3LB5A 4NDIA 3L7XA 1KPEA 1GUPA
chains in the Genus database with same CATH superfamily
3R6FA 3SZQA 3ANOA 3SP4A 4EQHA 4ZGLA 1KPFA 5I2FA 3O1XA 1FITA 1KPBA 3OHEA 4NJXA 2R7CA 4NDHA 3O1CA 2POFA 3OJ7A 6FITA 4XBAA 1Z84A 3N1TA 4I5TA 1ZWJA 5I2EA 6RHNA 2LJWA 2H39A 5ED3A 5IPBA 5IPEA 3N1SA 1GUQA 3OMFA 4NDGA 4FITA 4QEBA 5IPCA 1FHIA 4G0JA 3I4SA 5EMTA 2FHIA 3BLAA 3O1ZA 3RHNA 4ZKVA 3BL7A 1KPCA 1Y23A 4G0AA 1HXPA 3OXKA 4QDVA 3TW2A 1L9VA 2EO4A 5IN3A 5FITA 4INIA 4RHNA 4YKLB 1ST0A 5IPDA 1VLRA 2GU0A 4EQEA 2FITA 2R8FA 3BL9A 2Q4HA 2R7PA 5CS2A 4NDFA 4QDEA 4NJZA 4I5WA 1KPAA 1AV5A 1ST4A 1XMMA 1EMSA 5ED6A 2R7JA 2OIKA 4INCA 3QGZA 3I24A 3FITA 3KSVA 4NJYA 3SPDA 5BV3A 3IMIA 4NK0A 3O0MA 5RHNA 3P0TA 4ZKLA 1HXQA 3SPLA 4EQGA 1RZYA 4I5VA 3WO5A 2Q4LA 3NRDA 4EGUA 1XMLA 3LB5A 4NDIA 3L7XA 1KPEA 1GUPA
chains in the Genus database with same CATH topology
3R6FA 3SZQA 3ANOA 3SP4A 4EQHA 4ZGLA 1KPFA 5I2FA 3O1XA 1FITA 1KPBA 3OHEA 4NJXA 4NDHA 3O1CA 3OJ7A 6FITA 4XBAA 1Z84A 3N1TA 1ZWJA 5I2EA 6RHNA 2H39A 5ED3A 5IPBA 5IPEA 3N1SA 1GUQA 3OMFA 4NDGA 4FITA 4QEBA 5IPCA 1FHIA 3I4SA 5EMTA 2FHIA 3BLAA 3O1ZA 3RHNA 4ZKVA 3BL7A 1KPCA 1Y23A 1HXPA 3OXKA 4QDVA 3TW2A 2EO4A 5IN3A 5FITA 4INIA 4RHNA 4YKLB 1ST0A 5IPDA 1VLRA 4EQEA 2FITA 3BL9A 5CS2A 2Q4HA 4NDFA 4QDEA 4NJZA 1KPAA 1AV5A 1ST4A 1XMMA 1EMSA 5ED6A 2OIKA 4INCA 3QGZA 3I24A 3FITA 3KSVA 4NJYA 3SPDA 5BV3A 3IMIA 4NK0A 5RHNA 3O0MA 3P0TA 4ZKLA 1HXQA 3SPLA 4EQGA 1RZYA 3WO5A 2Q4LA 3NRDA 4EGUA 1XMLA 3LB5A 4NDIA 3L7XA 1KPEA 1GUPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3R6F A;  3SZQ A;  3ANO A;  3SP4 A;  4EQH A;  4ZGL A;  1KPF A;  5I2F A;  3O1X A;  1FIT A;  1KPB A;  3OHE A;  4NJX A;  4NDH A;  3O1C A;  3OJ7 A;  6FIT A;  4XBA A;  1Z84 A;  3N1T A;  1ZWJ A;  5I2E A;  6RHN A;  2H39 A;  5ED3 A;  5IPB A;  5IPE A;  3N1S A;  1GUQ A;  3OMF A;  4NDG A;  4FIT A;  4QEB A;  5IPC A;  1FHI A;  3I4S A;  5EMT A;  2FHI A;  3BLA A;  3O1Z A;  3RHN A;  4ZKV A;  3BL7 A;  1KPC A;  1Y23 A;  1HXP A;  3OXK A;  4QDV A;  3TW2 A;  2EO4 A;  5IN3 A;  5FIT A;  4INI A;  4RHN A;  4YKL B;  1ST0 A;  5IPD A;  1VLR A;  4EQE A;  2FIT A;  3BL9 A;  5CS2 A;  2Q4H A;  4NDF A;  4QDE A;  4NJZ A;  1KPA A;  1AV5 A;  1ST4 A;  1XMM A;  1EMS A;  5ED6 A;  2OIK A;  4INC A;  3QGZ A;  3I24 A;  3FIT A;  3KSV A;  4NJY A;  3SPD A;  5BV3 A;  3IMI A;  4NK0 A;  5RHN A;  3O0M A;  3P0T A;  4ZKL A;  1HXQ A;  3SPL A;  4EQG A;  1RZY A;  3WO5 A;  2Q4L A;  3NRD A;  4EGU A;  1XML A;  3LB5 A;  4NDI A;  3L7X A;  1KPE A;  1GUP A; 
#chains in the Genus database with same CATH topology
 3R6F A;  3SZQ A;  3ANO A;  3SP4 A;  4EQH A;  4ZGL A;  1KPF A;  5I2F A;  3O1X A;  1FIT A;  1KPB A;  3OHE A;  4NJX A;  2R7C A;  4NDH A;  3O1C A;  2POF A;  3OJ7 A;  6FIT A;  4XBA A;  1Z84 A;  3N1T A;  4I5T A;  1ZWJ A;  5I2E A;  6RHN A;  2LJW A;  2H39 A;  5ED3 A;  5IPB A;  5IPE A;  3N1S A;  1GUQ A;  3OMF A;  4NDG A;  4FIT A;  4QEB A;  5IPC A;  1FHI A;  4G0J A;  3I4S A;  5EMT A;  2FHI A;  3BLA A;  3O1Z A;  3RHN A;  4ZKV A;  3BL7 A;  1KPC A;  1Y23 A;  4G0A A;  1HXP A;  3OXK A;  4QDV A;  3TW2 A;  1L9V A;  2EO4 A;  5IN3 A;  5FIT A;  4INI A;  4RHN A;  4YKL B;  1ST0 A;  5IPD A;  1VLR A;  2GU0 A;  4EQE A;  2FIT A;  2R8F A;  3BL9 A;  2Q4H A;  2R7P A;  5CS2 A;  4NDF A;  4QDE A;  4NJZ A;  4I5W A;  1KPA A;  1AV5 A;  1ST4 A;  1XMM A;  1EMS A;  5ED6 A;  2R7J A;  2OIK A;  4INC A;  3QGZ A;  3I24 A;  3FIT A;  3KSV A;  4NJY A;  3SPD A;  5BV3 A;  3IMI A;  4NK0 A;  3O0M A;  5RHN A;  3P0T A;  4ZKL A;  1HXQ A;  3SPL A;  4EQG A;  1RZY A;  4I5V A;  3WO5 A;  2Q4L A;  3NRD A;  4EGU A;  1XML A;  3LB5 A;  4NDI A;  3L7X A;  1KPE A;  1GUP A; 
#chains in the Genus database with same CATH homology
 3R6F A;  3SZQ A;  3ANO A;  3SP4 A;  4EQH A;  4ZGL A;  1KPF A;  5I2F A;  3O1X A;  1FIT A;  1KPB A;  3OHE A;  4NJX A;  4NDH A;  3O1C A;  3OJ7 A;  6FIT A;  4XBA A;  1Z84 A;  3N1T A;  1ZWJ A;  5I2E A;  6RHN A;  2H39 A;  5ED3 A;  5IPB A;  5IPE A;  3N1S A;  1GUQ A;  3OMF A;  4NDG A;  4FIT A;  4QEB A;  5IPC A;  1FHI A;  3I4S A;  5EMT A;  2FHI A;  3BLA A;  3O1Z A;  3RHN A;  4ZKV A;  3BL7 A;  1KPC A;  1Y23 A;  1HXP A;  3OXK A;  4QDV A;  3TW2 A;  2EO4 A;  5IN3 A;  5FIT A;  4INI A;  4RHN A;  4YKL B;  1ST0 A;  5IPD A;  1VLR A;  4EQE A;  2FIT A;  3BL9 A;  5CS2 A;  2Q4H A;  4NDF A;  4QDE A;  4NJZ A;  1KPA A;  1AV5 A;  1ST4 A;  1XMM A;  1EMS A;  5ED6 A;  2OIK A;  4INC A;  3QGZ A;  3I24 A;  3FIT A;  3KSV A;  4NJY A;  3SPD A;  5BV3 A;  3IMI A;  4NK0 A;  5RHN A;  3O0M A;  3P0T A;  4ZKL A;  1HXQ A;  3SPL A;  4EQG A;  1RZY A;  3WO5 A;  2Q4L A;  3NRD A;  4EGU A;  1XML A;  3LB5 A;  4NDI A;  3L7X A;  1KPE A;  1GUP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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