4G0AA

Crystallographic analysis of rotavirus nsp2-rna complex reveals specific recognition of 5'-gg sequence for rtpase activity
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
312
structure length
312
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
pubmed doi rcsb
molecule keywords Non-structural protein 2
molecule tags Hydrolase/rna
source organism Simian 11 rotavirus
total genus 101
structure length 312
sequence length 312
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 4g0aA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 4g0aA01
2R7CA 2R8FA 1L9VA 2R7PA 2R7JA 2GU0A 4G0AA 4G0JA
chains in the Genus database with same CATH superfamily
2R7CA 1FHIA 1HXQA 5RHNA 3BL9A 3NRDA 2OIKA 3TW2A 5ED6A 4NDHA 3QGZA 1KPBA 4EQHA 3LB5A 5I2FA 4NDGA 3O1ZA 4NJZA 1L9VA 4QDVA 4I5VA 4NK0A 4EQGA 4NDFA 1AV5A 1XMMA 2POFA 5IPBA 4G0AA 4EQEA 4INCA 4NDIA 3WO5A 4INIA 1KPEA 1HXPA 1KPAA 3R6FA 5EMTA 5IPCA 1KPCA 4QDEA 1XMLA 1ST4A 3BL7A 3N1TA 2GU0A 3OJ7A 2Q4LA 4NJYA 1EMSA 3O1CA 3OMFA 4EGUA 6RHNA 1KPFA 1VLRA 2FHIA 5FITA 1ST0A 4XBAA 1Z84A 4QEBA 4I5WA 3OHEA 4ZGLA 3L7XA 6FITA 5ED3A 3O1XA 2R8FA 3OXKA 4NJXA 3SPDA 2R7JA 5IPDA 4FITA 5I2EA 4G0JA 5IN3A 4ZKLA 5CS2A 1ZWJA 3O0MA 2Q4HA 1FITA 3I4SA 3SPLA 3IMIA 1RZYA 2R7PA 3FITA 3KSVA 3N1SA 3RHNA 3BLAA 5BV3A 4YKLB 1GUPA 3P0TA 2EO4A 4I5TA 4RHNA 3SP4A 2FITA 4ZKVA 2H39A 2LJWA 3ANOA 3I24A 1GUQA 3SZQA 5IPEA 1Y23A
chains in the Genus database with same CATH topology
2R7CA 2R8FA 1L9VA 2R7PA 2R7JA 2GU0A 4G0AA 4G0JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R7C A;  2R8F A;  1L9V A;  2R7P A;  2R7J A;  2GU0 A;  4G0A A;  4G0J A; 
#chains in the Genus database with same CATH topology
 2R7C A;  1FHI A;  1HXQ A;  5RHN A;  3BL9 A;  3NRD A;  2OIK A;  3TW2 A;  5ED6 A;  4NDH A;  3QGZ A;  1KPB A;  4EQH A;  3LB5 A;  5I2F A;  4NDG A;  3O1Z A;  4NJZ A;  1L9V A;  4QDV A;  4I5V A;  4NK0 A;  4EQG A;  4NDF A;  1AV5 A;  1XMM A;  2POF A;  5IPB A;  4G0A A;  4EQE A;  4INC A;  4NDI A;  3WO5 A;  4INI A;  1KPE A;  1HXP A;  1KPA A;  3R6F A;  5EMT A;  5IPC A;  1KPC A;  4QDE A;  1XML A;  1ST4 A;  3BL7 A;  3N1T A;  2GU0 A;  3OJ7 A;  2Q4L A;  4NJY A;  1EMS A;  3O1C A;  3OMF A;  4EGU A;  6RHN A;  1KPF A;  1VLR A;  2FHI A;  5FIT A;  1ST0 A;  4XBA A;  1Z84 A;  4QEB A;  4I5W A;  3OHE A;  4ZGL A;  3L7X A;  6FIT A;  5ED3 A;  3O1X A;  2R8F A;  3OXK A;  4NJX A;  3SPD A;  2R7J A;  5IPD A;  4FIT A;  5I2E A;  4G0J A;  5IN3 A;  4ZKL A;  5CS2 A;  1ZWJ A;  3O0M A;  2Q4H A;  1FIT A;  3I4S A;  3SPL A;  3IMI A;  1RZY A;  2R7P A;  3FIT A;  3KSV A;  3N1S A;  3RHN A;  3BLA A;  5BV3 A;  4YKL B;  1GUP A;  3P0T A;  2EO4 A;  4I5T A;  4RHN A;  3SP4 A;  2FIT A;  4ZKV A;  2H39 A;  2LJW A;  3ANO A;  3I24 A;  1GUQ A;  3SZQ A;  5IPE A;  1Y23 A; 
#chains in the Genus database with same CATH homology
 2R7C A;  2R8F A;  1L9V A;  2R7P A;  2R7J A;  2GU0 A;  4G0A A;  4G0J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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