4G0AA

Crystallographic analysis of rotavirus nsp2-rna complex reveals specific recognition of 5'-gg sequence for rtpase activity
Total Genus 101
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
312
structure length
312
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
pubmed doi rcsb
molecule keywords Non-structural protein 2
molecule tags Hydrolase/rna
source organism Simian 11 rotavirus
total genus 101
structure length 312
sequence length 312
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 4g0aA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 4g0aA01
1L9VA 4G0AA 2R7PA 2GU0A 2R7CA 2R7JA 2R8FA 4G0JA
chains in the Genus database with same CATH superfamily
1KPEA 1FITA 4FITA 2R7JA 5ED3A 3O1CA 1ST4A 1XMLA 2FITA 3I4SA 2EO4A 5I2FA 3SPDA 1HXPA 4QDEA 5EMTA 4EQGA 5BV3A 2POFA 4NDFA 3LB5A 3N1SA 2R8FA 3OJ7A 3OMFA 4I5WA 1GUQA 5IPCA 4EGUA 4ZKVA 1ST0A 3WO5A 4YKLB 2LJWA 3OXKA 1Y23A 3BL9A 1KPAA 1AV5A 1VLRA 5CS2A 3OHEA 3O1ZA 4G0JA 2FHIA 3BL7A 2OIKA 1EMSA 3QGZA 5I2EA 4I5TA 4QDVA 3IMIA 4RHNA 5RHNA 3SZQA 3N1TA 6RHNA 4EQEA 4INCA 5ED6A 3SP4A 4QEBA 3TW2A 4ZGLA 4ZKLA 3R6FA 1KPFA 3KSVA 1HXQA 1L9VA 2Q4LA 2Q4HA 3I24A 3SPLA 5IPDA 3FITA 4G0AA 4NJXA 4NJYA 3BLAA 3RHNA 1XMMA 4I5VA 3L7XA 4EQHA 4NK0A 3P0TA 6FITA 3O0MA 1Z84A 5IN3A 4XBAA 4NDIA 1ZWJA 4NDGA 2H39A 5IPBA 4NDHA 1GUPA 1KPCA 2R7PA 2GU0A 4NJZA 3NRDA 3ANOA 1KPBA 5FITA 4INIA 1FHIA 2R7CA 5IPEA 1RZYA 3O1XA
chains in the Genus database with same CATH topology
1L9VA 4G0AA 2R7PA 2GU0A 2R7CA 2R7JA 2R8FA 4G0JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L9V A;  4G0A A;  2R7P A;  2GU0 A;  2R7C A;  2R7J A;  2R8F A;  4G0J A; 
#chains in the Genus database with same CATH topology
 1KPE A;  1FIT A;  4FIT A;  2R7J A;  5ED3 A;  3O1C A;  1ST4 A;  1XML A;  2FIT A;  3I4S A;  2EO4 A;  5I2F A;  3SPD A;  1HXP A;  4QDE A;  5EMT A;  4EQG A;  5BV3 A;  2POF A;  4NDF A;  3LB5 A;  3N1S A;  2R8F A;  3OJ7 A;  3OMF A;  4I5W A;  1GUQ A;  5IPC A;  4EGU A;  4ZKV A;  1ST0 A;  3WO5 A;  4YKL B;  2LJW A;  3OXK A;  1Y23 A;  3BL9 A;  1KPA A;  1AV5 A;  1VLR A;  5CS2 A;  3OHE A;  3O1Z A;  4G0J A;  2FHI A;  3BL7 A;  2OIK A;  1EMS A;  3QGZ A;  5I2E A;  4I5T A;  4QDV A;  3IMI A;  4RHN A;  5RHN A;  3SZQ A;  3N1T A;  6RHN A;  4EQE A;  4INC A;  5ED6 A;  3SP4 A;  4QEB A;  3TW2 A;  4ZGL A;  4ZKL A;  3R6F A;  1KPF A;  3KSV A;  1HXQ A;  1L9V A;  2Q4L A;  2Q4H A;  3I24 A;  3SPL A;  5IPD A;  3FIT A;  4G0A A;  4NJX A;  4NJY A;  3BLA A;  3RHN A;  1XMM A;  4I5V A;  3L7X A;  4EQH A;  4NK0 A;  3P0T A;  6FIT A;  3O0M A;  1Z84 A;  5IN3 A;  4XBA A;  4NDI A;  1ZWJ A;  4NDG A;  2H39 A;  5IPB A;  4NDH A;  1GUP A;  1KPC A;  2R7P A;  2GU0 A;  4NJZ A;  3NRD A;  3ANO A;  1KPB A;  5FIT A;  4INI A;  1FHI A;  2R7C A;  5IPE A;  1RZY A;  3O1X A; 
#chains in the Genus database with same CATH homology
 1L9V A;  4G0A A;  2R7P A;  2GU0 A;  2R7C A;  2R7J A;  2R8F A;  4G0J A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...