4G0AA

Crystallographic analysis of rotavirus nsp2-rna complex reveals specific recognition of 5'-gg sequence for rtpase activity
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
312
structure length
312
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/rna
source organism Simian 11 rotavirus
publication title Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
pubmed doi rcsb
molecule keywords Non-structural protein 2
total genus 101
structure length 312
sequence length 312
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 4g0aA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 4g0aA01
2R7JA 4G0AA 2R7PA 1L9VA 2GU0A 2R8FA 4G0JA 2R7CA
chains in the Genus database with same CATH superfamily
4NK0A 1AV5A 3BL7A 4EQHA 2FHIA 2FITA 4ZKVA 1GUPA 4NDFA 1KPEA 4NDGA 2Q4LA 4YKLB 4ZGLA 5IPBA 4I5TA 3L7XA 3IMIA 4QDEA 1VLRA 3FITA 5EMTA 1RZYA 3O1XA 5I2FA 3OHEA 1KPCA 4NJZA 1HXQA 3O1ZA 4INIA 3KSVA 3N1TA 4NDIA 6RHNA 2OIKA 1ZWJA 3BL9A 2R8FA 1FITA 1Y23A 5I2EA 2R7JA 3SP4A 3WO5A 3SPDA 4G0AA 4I5VA 5IPCA 3OJ7A 3ANOA 4QDVA 4ZKLA 4QEBA 3BLAA 3NRDA 3RHNA 1L9VA 4NJYA 3O0MA 3N1SA 3QGZA 3OMFA 1ST4A 5IN3A 3I4SA 1GUQA 2R7CA 4INCA 3O1CA 3TW2A 4EGUA 4XBAA 5BV3A 4NJXA 6FITA 1XMMA 5IPEA 4EQGA 1XMLA 3P0TA 1FHIA 1KPBA 2LJWA 2Q4HA 5IPDA 1KPAA 5RHNA 2R7PA 4RHNA 3SPLA 2GU0A 1EMSA 3SZQA 1KPFA 2POFA 4FITA 2H39A 2EO4A 1ST0A 3OXKA 1HXPA 3R6FA 4EQEA 1Z84A 3I24A 4NDHA 5CS2A 4I5WA 5FITA 5ED3A 3LB5A 4G0JA 5ED6A
chains in the Genus database with same CATH topology
2R7JA 4G0AA 2R7PA 1L9VA 2GU0A 2R8FA 4G0JA 2R7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R7J A;  4G0A A;  2R7P A;  1L9V A;  2GU0 A;  2R8F A;  4G0J A;  2R7C A; 
#chains in the Genus database with same CATH topology
 4NK0 A;  1AV5 A;  3BL7 A;  4EQH A;  2FHI A;  2FIT A;  4ZKV A;  1GUP A;  4NDF A;  1KPE A;  4NDG A;  2Q4L A;  4YKL B;  4ZGL A;  5IPB A;  4I5T A;  3L7X A;  3IMI A;  4QDE A;  1VLR A;  3FIT A;  5EMT A;  1RZY A;  3O1X A;  5I2F A;  3OHE A;  1KPC A;  4NJZ A;  1HXQ A;  3O1Z A;  4INI A;  3KSV A;  3N1T A;  4NDI A;  6RHN A;  2OIK A;  1ZWJ A;  3BL9 A;  2R8F A;  1FIT A;  1Y23 A;  5I2E A;  2R7J A;  3SP4 A;  3WO5 A;  3SPD A;  4G0A A;  4I5V A;  5IPC A;  3OJ7 A;  3ANO A;  4QDV A;  4ZKL A;  4QEB A;  3BLA A;  3NRD A;  3RHN A;  1L9V A;  4NJY A;  3O0M A;  3N1S A;  3QGZ A;  3OMF A;  1ST4 A;  5IN3 A;  3I4S A;  1GUQ A;  2R7C A;  4INC A;  3O1C A;  3TW2 A;  4EGU A;  4XBA A;  5BV3 A;  4NJX A;  6FIT A;  1XMM A;  5IPE A;  4EQG A;  1XML A;  3P0T A;  1FHI A;  1KPB A;  2LJW A;  2Q4H A;  5IPD A;  1KPA A;  5RHN A;  2R7P A;  4RHN A;  3SPL A;  2GU0 A;  1EMS A;  3SZQ A;  1KPF A;  2POF A;  4FIT A;  2H39 A;  2EO4 A;  1ST0 A;  3OXK A;  1HXP A;  3R6F A;  4EQE A;  1Z84 A;  3I24 A;  4NDH A;  5CS2 A;  4I5W A;  5FIT A;  5ED3 A;  3LB5 A;  4G0J A;  5ED6 A; 
#chains in the Genus database with same CATH homology
 2R7J A;  4G0A A;  2R7P A;  1L9V A;  2GU0 A;  2R8F A;  4G0J A;  2R7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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