4G0AA

Crystallographic analysis of rotavirus nsp2-rna complex reveals specific recognition of 5'-gg sequence for rtpase activity
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
312
structure length
312
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Simian 11 rotavirus
molecule keywords Non-structural protein 2
total genus 101
structure length 312
sequence length 312
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 4g0aA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 4g0aA01
2R7JA 4G0JA 2R7PA 2R8FA 2R7CA 4G0AA 1L9VA 2GU0A
chains in the Genus database with same CATH superfamily
2FITA 1AV5A 1ST0A 5I2EA 4ZGLA 5ED3A 5IPEA 1ST4A 3BL9A 3IMIA 1XMMA 1KPBA 3OJ7A 6FITA 4INCA 5IPDA 6RHNA 1KPCA 3SPLA 3N1TA 3RHNA 3O0MA 1FHIA 4I5TA 4NK0A 1FITA 3LB5A 3KSVA 5IN3A 4I5VA 4EQHA 4QDEA 4EQGA 4ZKLA 4NDIA 1KPFA 3P0TA 2LJWA 2EO4A 3TW2A 4I5WA 5ED6A 4XBAA 4NDGA 4INIA 4NJZA 3O1ZA 3SP4A 4G0AA 2POFA 3ANOA 4QDVA 2GU0A 5CS2A 3SPDA 4ZKVA 1KPAA 2FHIA 3N1SA 2OIKA 5IPCA 5FITA 1ZWJA 4G0JA 1XMLA 5I2FA 2R7PA 2R8FA 3OMFA 1L9VA 5IPBA 2Q4HA 2R7JA 4FITA 3SZQA 4NJYA 4QEBA 1EMSA 1Y23A 3NRDA 1RZYA 4EQEA 5RHNA 5BV3A 1GUQA 1Z84A 3R6FA 1GUPA 4NDFA 3I24A 3OXKA 3FITA 2H39A 4RHNA 2R7CA 3BLAA 3WO5A 3OHEA 3QGZA 2Q4LA 1HXPA 1HXQA 1VLRA 3I4SA 1KPEA 4NJXA 3O1CA 3BL7A 3L7XA 4YKLB 3O1XA 4NDHA 4EGUA 5EMTA
chains in the Genus database with same CATH topology
2R7JA 4G0JA 2R7PA 2R8FA 2R7CA 4G0AA 1L9VA 2GU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R7J A;  4G0J A;  2R7P A;  2R8F A;  2R7C A;  4G0A A;  1L9V A;  2GU0 A; 
#chains in the Genus database with same CATH topology
 2FIT A;  1AV5 A;  1ST0 A;  5I2E A;  4ZGL A;  5ED3 A;  5IPE A;  1ST4 A;  3BL9 A;  3IMI A;  1XMM A;  1KPB A;  3OJ7 A;  6FIT A;  4INC A;  5IPD A;  6RHN A;  1KPC A;  3SPL A;  3N1T A;  3RHN A;  3O0M A;  1FHI A;  4I5T A;  4NK0 A;  1FIT A;  3LB5 A;  3KSV A;  5IN3 A;  4I5V A;  4EQH A;  4QDE A;  4EQG A;  4ZKL A;  4NDI A;  1KPF A;  3P0T A;  2LJW A;  2EO4 A;  3TW2 A;  4I5W A;  5ED6 A;  4XBA A;  4NDG A;  4INI A;  4NJZ A;  3O1Z A;  3SP4 A;  4G0A A;  2POF A;  3ANO A;  4QDV A;  2GU0 A;  5CS2 A;  3SPD A;  4ZKV A;  1KPA A;  2FHI A;  3N1S A;  2OIK A;  5IPC A;  5FIT A;  1ZWJ A;  4G0J A;  1XML A;  5I2F A;  2R7P A;  2R8F A;  3OMF A;  1L9V A;  5IPB A;  2Q4H A;  2R7J A;  4FIT A;  3SZQ A;  4NJY A;  4QEB A;  1EMS A;  1Y23 A;  3NRD A;  1RZY A;  4EQE A;  5RHN A;  5BV3 A;  1GUQ A;  1Z84 A;  3R6F A;  1GUP A;  4NDF A;  3I24 A;  3OXK A;  3FIT A;  2H39 A;  4RHN A;  2R7C A;  3BLA A;  3WO5 A;  3OHE A;  3QGZ A;  2Q4L A;  1HXP A;  1HXQ A;  1VLR A;  3I4S A;  1KPE A;  4NJX A;  3O1C A;  3BL7 A;  3L7X A;  4YKL B;  3O1X A;  4NDH A;  4EGU A;  5EMT A; 
#chains in the Genus database with same CATH homology
 2R7J A;  4G0J A;  2R7P A;  2R8F A;  2R7C A;  4G0A A;  1L9V A;  2GU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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