4I5WA

Crystal structure of yeast ap4a phosphorylase apa2 in complex with amp
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
319
structure length
292
Chain Sequence
MIEENLKQKIHDKFVAAKKNGHLKVTHAESKKLKDPQTTTQYWVTFAPSLALDPFANPDEELVVTEDLNGDGEYKLLLNKFPVVPEHSLLVTSEFKDQRSALTPSDLMTAYNVLCSLQGCERYLVFYNCGPHSGSSQDHKHLQIMQMPEKFIPFQDVLCNGKDHFLPTFNAEPLQDDKVSFAHFVLPLPESSDQVDEDLLAMCYVSLMQRALTFFQDLTKSYNVLLTKKWICVVPRSHAKSGPPLMLNINSTGYCGMILVKDREKLENLTEDPHLVDKSLLQCGFPNTAGQK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of yeast Apa2 reveal catalytic insights into a canonical AP4A phosphorylase of the histidine triad superfamily
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords 5',5'''-P-1,P-4-tetraphosphate phosphorylase 2
total genus 85
structure length 292
sequence length 319
chains with identical sequence B
ec nomenclature ec 2.7.7.5: Sulfate adenylyltransferase (ADP).
pdb deposition date 2012-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09830 ATP_transf ATP adenylyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.70 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT family, subunit A 4i5wA00
4I5TA 4I5WA 4I5VA
chains in the Genus database with same CATH superfamily
4NDHA 1KPFA 2R7JA 1KPBA 5IPCA 5EMTA 2LJWA 3OMFA 5I2FA 3SZQA 1RZYA 4ZKVA 1GUQA 4NDFA 2POFA 4QDVA 3L7XA 2FHIA 4XBAA 4EGUA 3BLAA 1GUPA 3ANOA 1L9VA 2H39A 5FITA 3R6FA 4NDGA 5BV3A 2R8FA 3TW2A 5IN3A 3SP4A 4FITA 4G0AA 2EO4A 1KPAA 4G0JA 3QGZA 4EQEA 4RHNA 3KSVA 1EMSA 3IMIA 4I5TA 3O1ZA 3I24A 5ED3A 4QDEA 4EQGA 2Q4LA 4EQHA 1KPCA 3O0MA 1XMLA 5IPDA 3O1XA 1FITA 3OJ7A 4ZKLA 1Y23A 1XMMA 1Z84A 3P0TA 5IPBA 3BL7A 3OHEA 3N1SA 3NRDA 3O1CA 4NK0A 4INCA 3RHNA 4NJZA 5ED6A 3N1TA 1HXQA 5CS2A 5I2EA 2FITA 3BL9A 3I4SA 4I5WA 4ZGLA 4YKLB 6FITA 1ST4A 1KPEA 1HXPA 3LB5A 1FHIA 4I5VA 3FITA 6RHNA 3SPDA 2R7PA 2GU0A 1ST0A 3WO5A 4INIA 1AV5A 4NDIA 2OIKA 2Q4HA 3SPLA 5RHNA 5IPEA 4NJXA 1ZWJA 3OXKA 1VLRA 2R7CA 4NJYA 4QEBA
chains in the Genus database with same CATH topology
4I5TA 4I5WA 2LJWA 4I5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I5T A;  4I5W A;  4I5V A; 
#chains in the Genus database with same CATH topology
 4NDH A;  1KPF A;  2R7J A;  1KPB A;  5IPC A;  5EMT A;  2LJW A;  3OMF A;  5I2F A;  3SZQ A;  1RZY A;  4ZKV A;  1GUQ A;  4NDF A;  2POF A;  4QDV A;  3L7X A;  2FHI A;  4XBA A;  4EGU A;  3BLA A;  1GUP A;  3ANO A;  1L9V A;  2H39 A;  5FIT A;  3R6F A;  4NDG A;  5BV3 A;  2R8F A;  3TW2 A;  5IN3 A;  3SP4 A;  4FIT A;  4G0A A;  2EO4 A;  1KPA A;  4G0J A;  3QGZ A;  4EQE A;  4RHN A;  3KSV A;  1EMS A;  3IMI A;  4I5T A;  3O1Z A;  3I24 A;  5ED3 A;  4QDE A;  4EQG A;  2Q4L A;  4EQH A;  1KPC A;  3O0M A;  1XML A;  5IPD A;  3O1X A;  1FIT A;  3OJ7 A;  4ZKL A;  1Y23 A;  1XMM A;  1Z84 A;  3P0T A;  5IPB A;  3BL7 A;  3OHE A;  3N1S A;  3NRD A;  3O1C A;  4NK0 A;  4INC A;  3RHN A;  4NJZ A;  5ED6 A;  3N1T A;  1HXQ A;  5CS2 A;  5I2E A;  2FIT A;  3BL9 A;  3I4S A;  4I5W A;  4ZGL A;  4YKL B;  6FIT A;  1ST4 A;  1KPE A;  1HXP A;  3LB5 A;  1FHI A;  4I5V A;  3FIT A;  6RHN A;  3SPD A;  2R7P A;  2GU0 A;  1ST0 A;  3WO5 A;  4INI A;  1AV5 A;  4NDI A;  2OIK A;  2Q4H A;  3SPL A;  5RHN A;  5IPE A;  4NJX A;  1ZWJ A;  3OXK A;  1VLR A;  2R7C A;  4NJY A;  4QEB A; 
#chains in the Genus database with same CATH homology
 4I5T A;  4I5W A;  2LJW A;  4I5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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