4G0AA

Crystallographic analysis of rotavirus nsp2-rna complex reveals specific recognition of 5'-gg sequence for rtpase activity
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
312
structure length
312
Chain Sequence
AELACFCYPHLENDSYKFIPFNNLAIKAMLTAKVDKKDMDKFYDSIIYGIAPPPQFKKRYNTNDNSRGMNFETIMFTKVAMLICEALNSLKVTQANVSNVLSRVVSIRHLENLVIRKENPQDILFHSKDLLLKSTLIAIGQSKEIETTITAEGGEIVFQNAAFTMWKLTYLEHQLMPILDQNFIEYKVTLNEDKPISDVHVKELVAELRWQYNKFAVITHGKGHYRIVKYSSVANHADRVYATFKSNVKTGVNNDFNLLDQRIIWQNWYAFTSSMKQGNTLDVCKRLLFQKMKPEKNPFKGLSTDRKMDEVS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Simian 11 rotavirus
molecule keywords Non-structural protein 2
total genus 101
structure length 312
sequence length 312
chains with identical sequence B, C, D
ec nomenclature ec 3.6.4.-:
pdb deposition date 2012-07-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02509 Rota_NS35 Rotavirus non-structural protein 35
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.20 Alpha Beta 2-Layer Sandwich HIT family, subunit A Rotavirus NSP2 fragment, C-terminal domain 4g0aA02
3.90.1400.10 Alpha Beta Alpha-Beta Complex Rotavirus NSP2 fragment, N-terminal domain Rotavirus NSP2 fragment, N-terminal domain 4g0aA01
4G0AA 1L9VA 2R7JA 2R7CA 2R7PA 4G0JA 2R8FA 2GU0A
chains in the Genus database with same CATH superfamily
3RHNA 2H39A 3O1CA 4NDGA 4QDEA 4QDVA 2R8FA 4I5TA 4NJXA 3O0MA 5IN3A 2FHIA 3L7XA 4INIA 1FHIA 5IPCA 1L9VA 4FITA 1XMMA 3O1XA 5IPDA 1GUQA 4INCA 3N1TA 3LB5A 3BL7A 4G0JA 5IPEA 3QGZA 3SZQA 2R7JA 3IMIA 2Q4LA 1KPEA 1ZWJA 5ED6A 1AV5A 1KPAA 2LJWA 3WO5A 1KPBA 6FITA 4EQHA 4RHNA 3NRDA 6RHNA 1GUPA 4EGUA 1Z84A 3SPLA 3I24A 4NJYA 3N1SA 5CS2A 4NDIA 4NDFA 2FITA 3OHEA 4I5WA 5IPBA 3OMFA 5EMTA 3TW2A 5RHNA 3OXKA 3OJ7A 5ED3A 4ZKVA 4EQGA 4G0AA 5I2EA 4QEBA 1FITA 2GU0A 1VLRA 2Q4HA 3BL9A 5FITA 1EMSA 3P0TA 2EO4A 1KPFA 1KPCA 1RZYA 3SPDA 4I5VA 3FITA 3KSVA 2R7CA 2R7PA 3BLAA 1ST0A 3O1ZA 2OIKA 4NDHA 4XBAA 2POFA 3R6FA 1HXPA 4YKLB 3I4SA 4ZKLA 4EQEA 1XMLA 4NK0A 5I2FA 3SP4A 1ST4A 3ANOA 1Y23A 5BV3A 4NJZA 4ZGLA 1HXQA
chains in the Genus database with same CATH topology
4G0AA 1L9VA 2R7JA 2R7CA 2R7PA 4G0JA 2R8FA 2GU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G0A A;  1L9V A;  2R7J A;  2R7C A;  2R7P A;  4G0J A;  2R8F A;  2GU0 A; 
#chains in the Genus database with same CATH topology
 3RHN A;  2H39 A;  3O1C A;  4NDG A;  4QDE A;  4QDV A;  2R8F A;  4I5T A;  4NJX A;  3O0M A;  5IN3 A;  2FHI A;  3L7X A;  4INI A;  1FHI A;  5IPC A;  1L9V A;  4FIT A;  1XMM A;  3O1X A;  5IPD A;  1GUQ A;  4INC A;  3N1T A;  3LB5 A;  3BL7 A;  4G0J A;  5IPE A;  3QGZ A;  3SZQ A;  2R7J A;  3IMI A;  2Q4L A;  1KPE A;  1ZWJ A;  5ED6 A;  1AV5 A;  1KPA A;  2LJW A;  3WO5 A;  1KPB A;  6FIT A;  4EQH A;  4RHN A;  3NRD A;  6RHN A;  1GUP A;  4EGU A;  1Z84 A;  3SPL A;  3I24 A;  4NJY A;  3N1S A;  5CS2 A;  4NDI A;  4NDF A;  2FIT A;  3OHE A;  4I5W A;  5IPB A;  3OMF A;  5EMT A;  3TW2 A;  5RHN A;  3OXK A;  3OJ7 A;  5ED3 A;  4ZKV A;  4EQG A;  4G0A A;  5I2E A;  4QEB A;  1FIT A;  2GU0 A;  1VLR A;  2Q4H A;  3BL9 A;  5FIT A;  1EMS A;  3P0T A;  2EO4 A;  1KPF A;  1KPC A;  1RZY A;  3SPD A;  4I5V A;  3FIT A;  3KSV A;  2R7C A;  2R7P A;  3BLA A;  1ST0 A;  3O1Z A;  2OIK A;  4NDH A;  4XBA A;  2POF A;  3R6F A;  1HXP A;  4YKL B;  3I4S A;  4ZKL A;  4EQE A;  1XML A;  4NK0 A;  5I2F A;  3SP4 A;  1ST4 A;  3ANO A;  1Y23 A;  5BV3 A;  4NJZ A;  4ZGL A;  1HXQ A; 
#chains in the Genus database with same CATH homology
 4G0A A;  1L9V A;  2R7J A;  2R7C A;  2R7P A;  4G0J A;  2R8F A;  2GU0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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