The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
45
|
sequence length |
198
|
structure length |
147
|
Chain Sequence |
EKYKNILEKLEWYKNKSSEKYEFGIYEIDKREVFITTKYSYGFVNNKPLLPGHILLTTLKKKKHYNDLDIEEIIDINLLCNFMCYIMGNLFNTTDFSIAIQDGKEAGQTVDHVHIHIIPRKINDIRSIEQMEEEANLIKSYINEKFS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action.
pubmed doi rcsb |
| molecule keywords |
Histidine triad protein
|
| molecule tags |
Hydrolase
|
| source organism |
Plasmodium falciparum (isolate 3d7)
|
| total genus |
45
|
| structure length |
147
|
| sequence length |
198
|
| ec nomenclature | |
| pdb deposition date | 2015-07-23 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01230 | HIT | HIT domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT-like |
#chains in the Genus database with same CATH superfamily 5IPE A; 5ED6 A; 3I4S A; 1FIT A; 3ANO A; 3O0M A; 3SZQ A; 3NRD A; 1KPB A; 3WO5 A; 1ST4 A; 5BV3 A; 4EQG A; 6FIT A; 3RHN A; 4YKL B; 3SPL A; 2FHI A; 3OMF A; 3LB5 A; 4EGU A; 5I2F A; 5IPB A; 1KPC A; 2FIT A; 1KPF A; 3N1T A; 3O1C A; 4INI A; 1GUP A; 4NDF A; 4NK0 A; 6RHN A; 3SP4 A; 3O1Z A; 1HXQ A; 1Z84 A; 4QEB A; 4QDE A; 5EMT A; 3BLA A; 3L7X A; 1ZWJ A; 5CS2 A; 3KSV A; 4ZKL A; 3OJ7 A; 1ST0 A; 5IPD A; 2H39 A; 1XML A; 3OHE A; 3TW2 A; 3R6F A; 1KPA A; 4NDG A; 3O1X A; 2EO4 A; 4EQH A; 4NJX A; 2Q4H A; 5I2E A; 1Y23 A; 4NJZ A; 4RHN A; 1AV5 A; 3BL9 A; 1EMS A; 4ZKV A; 3I24 A; 4XBA A; 4QDV A; 3FIT A; 1VLR A; 3OXK A; 1XMM A; 5IN3 A; 3N1S A; 2OIK A; 3SPD A; 3IMI A; 3QGZ A; 4FIT A; 5ED3 A; 4EQE A; 1GUQ A; 1RZY A; 3BL7 A; 4NDI A; 1FHI A; 1KPE A; 5IPC A; 2Q4L A; 4NJY A; 4ZGL A; 5FIT A; 3P0T A; 5RHN A; 1HXP A; 4INC A; 4NDH A; #chains in the Genus database with same CATH topology 5IPE A; 5ED6 A; 3I4S A; 1FIT A; 3ANO A; 3O0M A; 4G0J A; 3SZQ A; 3NRD A; 1KPB A; 3WO5 A; 1ST4 A; 5BV3 A; 4EQG A; 6FIT A; 3RHN A; 4YKL B; 3SPL A; 2FHI A; 1L9V A; 4G0A A; 3OMF A; 3LB5 A; 4EGU A; 2R7C A; 5I2F A; 5IPB A; 2R8F A; 1KPC A; 2FIT A; 1KPF A; 3N1T A; 3O1C A; 4INI A; 1GUP A; 4NDF A; 4NK0 A; 6RHN A; 3SP4 A; 3O1Z A; 1HXQ A; 4I5W A; 1Z84 A; 4QEB A; 4I5V A; 4QDE A; 2POF A; 5EMT A; 3BLA A; 3L7X A; 1ZWJ A; 5CS2 A; 3KSV A; 4ZKL A; 3OJ7 A; 1ST0 A; 5IPD A; 2H39 A; 1XML A; 3OHE A; 3TW2 A; 3R6F A; 2R7J A; 1KPA A; 4NDG A; 3O1X A; 2EO4 A; 4EQH A; 4NJX A; 2Q4H A; 5I2E A; 1Y23 A; 2R7P A; 4NJZ A; 4RHN A; 1AV5 A; 3BL9 A; 1EMS A; 4ZKV A; 3I24 A; 4XBA A; 2GU0 A; 4QDV A; 3FIT A; 1VLR A; 3OXK A; 1XMM A; 5IN3 A; 3N1S A; 2OIK A; 3SPD A; 3IMI A; 3QGZ A; 4FIT A; 5ED3 A; 4EQE A; 1GUQ A; 1RZY A; 3BL7 A; 4NDI A; 1FHI A; 1KPE A; 4I5T A; 5IPC A; 2Q4L A; 2LJW A; 4NJY A; 4ZGL A; 5FIT A; 3P0T A; 5RHN A; 1HXP A; 4INC A; 4NDH A; #chains in the Genus database with same CATH homology 5IPE A; 5ED6 A; 3I4S A; 1FIT A; 3ANO A; 3O0M A; 3SZQ A; 3NRD A; 1KPB A; 3WO5 A; 1ST4 A; 5BV3 A; 4EQG A; 6FIT A; 3RHN A; 4YKL B; 3SPL A; 2FHI A; 3OMF A; 3LB5 A; 4EGU A; 5I2F A; 5IPB A; 1KPC A; 2FIT A; 1KPF A; 3N1T A; 3O1C A; 4INI A; 1GUP A; 4NDF A; 4NK0 A; 6RHN A; 3SP4 A; 3O1Z A; 1HXQ A; 1Z84 A; 4QEB A; 4QDE A; 5EMT A; 3BLA A; 3L7X A; 1ZWJ A; 5CS2 A; 3KSV A; 4ZKL A; 3OJ7 A; 1ST0 A; 5IPD A; 2H39 A; 1XML A; 3OHE A; 3TW2 A; 3R6F A; 1KPA A; 4NDG A; 3O1X A; 2EO4 A; 4EQH A; 4NJX A; 2Q4H A; 5I2E A; 1Y23 A; 4NJZ A; 4RHN A; 1AV5 A; 3BL9 A; 1EMS A; 4ZKV A; 3I24 A; 4XBA A; 4QDV A; 3FIT A; 1VLR A; 3OXK A; 1XMM A; 5IN3 A; 3N1S A; 2OIK A; 3SPD A; 3IMI A; 3QGZ A; 4FIT A; 5ED3 A; 4EQE A; 1GUQ A; 1RZY A; 3BL7 A; 4NDI A; 1FHI A; 1KPE A; 5IPC A; 2Q4L A; 4NJY A; 4ZGL A; 5FIT A; 3P0T A; 5RHN A; 1HXP A; 4INC A; 4NDH A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
