5ED6A

Crystal structure of human hint1 h114a mutant complexing with atp
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
113
structure length
113
Chain Sequence
GGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLAVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Homo sapiens
publication title Convergent Regulation of Transcriptional Repression by a Second Messenger and Post-translation Modifications
rcsb
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 31
structure length 113
sequence length 113
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2015-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 5ed6A00
3OJ7A 4ZKVA 2Q4HA 1XMMA 1GUPA 4QDEA 6FITA 5BV3A 4XBAA 1KPAA 5I2EA 3BL9A 3OXKA 3WO5A 3R6FA 5EMTA 3O1XA 3I4SA 4NDFA 1RZYA 3RHNA 4EGUA 5IN3A 1KPCA 1VLRA 3OHEA 1HXPA 5IPDA 4FITA 4QDVA 4YKLB 1ST0A 5I2FA 3O1CA 1Y23A 3BLAA 4NJYA 5RHNA 4ZKLA 3I24A 4QEBA 3KSVA 4NJXA 5IPEA 1HXQA 3IMIA 1KPEA 5ED3A 1KPBA 3ANOA 3NRDA 5FITA 4INCA 5ED6A 4NK0A 3QGZA 5IPCA 4NDGA 4NDIA 1ZWJA 2OIKA 4ZGLA 3N1TA 3L7XA 1ST4A 3P0TA 4INIA 3BL7A 3O0MA 1KPFA 1AV5A 3SP4A 3O1ZA 3SZQA 4EQEA 1GUQA 5CS2A 2H39A 2EO4A 6RHNA 2FHIA 3FITA 3OMFA 2Q4LA 2FITA 5IPBA 4EQHA 1FHIA 3LB5A 3N1SA 4RHNA 4EQGA 1Z84A 1FITA 1XMLA 3SPDA 4NDHA 3SPLA 4NJZA 1EMSA 3TW2A
chains in the Genus database with same CATH superfamily
3OJ7A 4ZKVA 2Q4HA 1XMMA 1GUPA 4QDEA 6FITA 5BV3A 4I5WA 4XBAA 1KPAA 5I2EA 3BL9A 3OXKA 3WO5A 3R6FA 5EMTA 3O1XA 3I4SA 4NDFA 1RZYA 2R7JA 3RHNA 2POFA 4EGUA 1L9VA 5IN3A 2LJWA 1KPCA 4I5TA 1VLRA 3OHEA 1HXPA 5IPDA 4FITA 4QDVA 4YKLB 1ST0A 5I2FA 3O1CA 1Y23A 3BLAA 4NJYA 5RHNA 4ZKLA 3I24A 4QEBA 3KSVA 4NJXA 2GU0A 5IPEA 1HXQA 3IMIA 1KPEA 1KPBA 5ED3A 3ANOA 3NRDA 5FITA 4INCA 5ED6A 2R8FA 4NK0A 3QGZA 5IPCA 4NDGA 2R7CA 4NDIA 1ZWJA 2OIKA 4G0AA 4ZGLA 3N1TA 3L7XA 1ST4A 3P0TA 4INIA 3BL7A 3O0MA 1KPFA 1AV5A 3SP4A 3O1ZA 3SZQA 4EQEA 1GUQA 5CS2A 2H39A 2EO4A 4I5VA 6RHNA 2FHIA 3FITA 3OMFA 2Q4LA 2FITA 5IPBA 2R7PA 4EQHA 1FHIA 3LB5A 3N1SA 4RHNA 4EQGA 1Z84A 1FITA 1XMLA 3SPDA 4NDHA 3SPLA 4G0JA 4NJZA 1EMSA 3TW2A
chains in the Genus database with same CATH topology
3OJ7A 4ZKVA 2Q4HA 1XMMA 1GUPA 4QDEA 6FITA 5BV3A 4XBAA 1KPAA 5I2EA 3BL9A 3OXKA 3WO5A 3R6FA 5EMTA 3O1XA 3I4SA 4NDFA 1RZYA 3RHNA 4EGUA 5IN3A 1KPCA 1VLRA 3OHEA 1HXPA 5IPDA 4FITA 4QDVA 4YKLB 1ST0A 5I2FA 3O1CA 1Y23A 3BLAA 4NJYA 5RHNA 4ZKLA 3I24A 4QEBA 3KSVA 4NJXA 5IPEA 1HXQA 3IMIA 1KPEA 5ED3A 1KPBA 3ANOA 3NRDA 5FITA 4INCA 5ED6A 4NK0A 3QGZA 5IPCA 4NDGA 4NDIA 1ZWJA 2OIKA 4ZGLA 3N1TA 3L7XA 1ST4A 3P0TA 4INIA 3BL7A 3O0MA 1KPFA 1AV5A 3SP4A 3O1ZA 3SZQA 4EQEA 1GUQA 5CS2A 2H39A 2EO4A 6RHNA 2FHIA 3FITA 3OMFA 2Q4LA 2FITA 5IPBA 4EQHA 1FHIA 3LB5A 3N1SA 4RHNA 4EQGA 1Z84A 1FITA 1XMLA 3SPDA 4NDHA 3SPLA 4NJZA 1EMSA 3TW2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OJ7 A;  4ZKV A;  2Q4H A;  1XMM A;  1GUP A;  4QDE A;  6FIT A;  5BV3 A;  4XBA A;  1KPA A;  5I2E A;  3BL9 A;  3OXK A;  3WO5 A;  3R6F A;  5EMT A;  3O1X A;  3I4S A;  4NDF A;  1RZY A;  3RHN A;  4EGU A;  5IN3 A;  1KPC A;  1VLR A;  3OHE A;  1HXP A;  5IPD A;  4FIT A;  4QDV A;  4YKL B;  1ST0 A;  5I2F A;  3O1C A;  1Y23 A;  3BLA A;  4NJY A;  5RHN A;  4ZKL A;  3I24 A;  4QEB A;  3KSV A;  4NJX A;  5IPE A;  1HXQ A;  3IMI A;  1KPE A;  5ED3 A;  1KPB A;  3ANO A;  3NRD A;  5FIT A;  4INC A;  5ED6 A;  4NK0 A;  3QGZ A;  5IPC A;  4NDG A;  4NDI A;  1ZWJ A;  2OIK A;  4ZGL A;  3N1T A;  3L7X A;  1ST4 A;  3P0T A;  4INI A;  3BL7 A;  3O0M A;  1KPF A;  1AV5 A;  3SP4 A;  3O1Z A;  3SZQ A;  4EQE A;  1GUQ A;  5CS2 A;  2H39 A;  2EO4 A;  6RHN A;  2FHI A;  3FIT A;  3OMF A;  2Q4L A;  2FIT A;  5IPB A;  4EQH A;  1FHI A;  3LB5 A;  3N1S A;  4RHN A;  4EQG A;  1Z84 A;  1FIT A;  1XML A;  3SPD A;  4NDH A;  3SPL A;  4NJZ A;  1EMS A;  3TW2 A; 
#chains in the Genus database with same CATH topology
 3OJ7 A;  4ZKV A;  2Q4H A;  1XMM A;  1GUP A;  4QDE A;  6FIT A;  5BV3 A;  4I5W A;  4XBA A;  1KPA A;  5I2E A;  3BL9 A;  3OXK A;  3WO5 A;  3R6F A;  5EMT A;  3O1X A;  3I4S A;  4NDF A;  1RZY A;  2R7J A;  3RHN A;  2POF A;  4EGU A;  1L9V A;  5IN3 A;  2LJW A;  1KPC A;  4I5T A;  1VLR A;  3OHE A;  1HXP A;  5IPD A;  4FIT A;  4QDV A;  4YKL B;  1ST0 A;  5I2F A;  3O1C A;  1Y23 A;  3BLA A;  4NJY A;  5RHN A;  4ZKL A;  3I24 A;  4QEB A;  3KSV A;  4NJX A;  2GU0 A;  5IPE A;  1HXQ A;  3IMI A;  1KPE A;  1KPB A;  5ED3 A;  3ANO A;  3NRD A;  5FIT A;  4INC A;  5ED6 A;  2R8F A;  4NK0 A;  3QGZ A;  5IPC A;  4NDG A;  2R7C A;  4NDI A;  1ZWJ A;  2OIK A;  4G0A A;  4ZGL A;  3N1T A;  3L7X A;  1ST4 A;  3P0T A;  4INI A;  3BL7 A;  3O0M A;  1KPF A;  1AV5 A;  3SP4 A;  3O1Z A;  3SZQ A;  4EQE A;  1GUQ A;  5CS2 A;  2H39 A;  2EO4 A;  4I5V A;  6RHN A;  2FHI A;  3FIT A;  3OMF A;  2Q4L A;  2FIT A;  5IPB A;  2R7P A;  4EQH A;  1FHI A;  3LB5 A;  3N1S A;  4RHN A;  4EQG A;  1Z84 A;  1FIT A;  1XML A;  3SPD A;  4NDH A;  3SPL A;  4G0J A;  4NJZ A;  1EMS A;  3TW2 A; 
#chains in the Genus database with same CATH homology
 3OJ7 A;  4ZKV A;  2Q4H A;  1XMM A;  1GUP A;  4QDE A;  6FIT A;  5BV3 A;  4XBA A;  1KPA A;  5I2E A;  3BL9 A;  3OXK A;  3WO5 A;  3R6F A;  5EMT A;  3O1X A;  3I4S A;  4NDF A;  1RZY A;  3RHN A;  4EGU A;  5IN3 A;  1KPC A;  1VLR A;  3OHE A;  1HXP A;  5IPD A;  4FIT A;  4QDV A;  4YKL B;  1ST0 A;  5I2F A;  3O1C A;  1Y23 A;  3BLA A;  4NJY A;  5RHN A;  4ZKL A;  3I24 A;  4QEB A;  3KSV A;  4NJX A;  5IPE A;  1HXQ A;  3IMI A;  1KPE A;  5ED3 A;  1KPB A;  3ANO A;  3NRD A;  5FIT A;  4INC A;  5ED6 A;  4NK0 A;  3QGZ A;  5IPC A;  4NDG A;  4NDI A;  1ZWJ A;  2OIK A;  4ZGL A;  3N1T A;  3L7X A;  1ST4 A;  3P0T A;  4INI A;  3BL7 A;  3O0M A;  1KPF A;  1AV5 A;  3SP4 A;  3O1Z A;  3SZQ A;  4EQE A;  1GUQ A;  5CS2 A;  2H39 A;  2EO4 A;  6RHN A;  2FHI A;  3FIT A;  3OMF A;  2Q4L A;  2FIT A;  5IPB A;  4EQH A;  1FHI A;  3LB5 A;  3N1S A;  4RHN A;  4EQG A;  1Z84 A;  1FIT A;  1XML A;  3SPD A;  4NDH A;  3SPL A;  4NJZ A;  1EMS A;  3TW2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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