5ED6A

Crystal structure of human hint1 h114a mutant complexing with atp
Total Genus 31
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
31
sequence length
113
structure length
113
Chain Sequence
GGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLAVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Convergent Regulation of Transcriptional Repression by a Second Messenger and Post-translation Modifications
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 31
structure length 113
sequence length 113
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2015-10-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 5ed6A00
1ZWJA 4NJYA 5EMTA 1KPAA 6RHNA 5BV3A 4YKLB 3N1TA 4INCA 1Z84A 4EQEA 2H39A 3O1XA 1HXQA 4ZGLA 5CS2A 3R6FA 3BL9A 3SPDA 4EQGA 1HXPA 5RHNA 1Y23A 3I4SA 4NDGA 3I24A 3WO5A 3LB5A 4FITA 4QDVA 4NDIA 5IPCA 5IPBA 1KPFA 4RHNA 4NK0A 3SZQA 5ED3A 4INIA 1VLRA 1GUPA 4NJXA 3KSVA 4NDFA 2FITA 3ANOA 1XMLA 5IPEA 5IN3A 3N1SA 1KPEA 5I2EA 4ZKLA 4NJZA 3NRDA 3IMIA 3O1ZA 4QDEA 3QGZA 4EGUA 3RHNA 3OMFA 3TW2A 2Q4HA 4XBAA 4ZKVA 3SPLA 2FHIA 1RZYA 3P0TA 5FITA 2Q4LA 3O0MA 3OHEA 4NDHA 1KPBA 1XMMA 2OIKA 1EMSA 2EO4A 3BL7A 1FHIA 3FITA 1ST0A 6FITA 1AV5A 3BLAA 5ED6A 3SP4A 4QEBA 5I2FA 1GUQA 3OXKA 5IPDA 1FITA 3OJ7A 4EQHA 1KPCA 3O1CA 3L7XA 1ST4A
chains in the Genus database with same CATH superfamily
1ZWJA 4NJYA 5EMTA 1KPAA 6RHNA 2GU0A 2R7CA 5BV3A 4YKLB 3N1TA 4INCA 1Z84A 4EQEA 2H39A 3O1XA 1HXQA 4ZGLA 5CS2A 4I5VA 3R6FA 3BL9A 3SPDA 4EQGA 1HXPA 5RHNA 1Y23A 3I4SA 4NDGA 3I24A 3WO5A 4I5WA 3LB5A 4FITA 4QDVA 4NDIA 5IPCA 5IPBA 1KPFA 4RHNA 4NK0A 3SZQA 5ED3A 4INIA 1VLRA 1GUPA 4NJXA 3KSVA 4NDFA 2FITA 3ANOA 2LJWA 1XMLA 4G0AA 5IPEA 5IN3A 2R7PA 3N1SA 1KPEA 5I2EA 2R8FA 4ZKLA 4NJZA 3NRDA 3IMIA 3O1ZA 4QDEA 3QGZA 4G0JA 4EGUA 3RHNA 3OMFA 3TW2A 2R7JA 2Q4HA 4XBAA 4ZKVA 3SPLA 2FHIA 1RZYA 3P0TA 5FITA 2Q4LA 3O0MA 3OHEA 4NDHA 1KPBA 1XMMA 2OIKA 1EMSA 2EO4A 3BL7A 1FHIA 3FITA 1ST0A 6FITA 4I5TA 1AV5A 3BLAA 5ED6A 3SP4A 4QEBA 5I2FA 1GUQA 1L9VA 3OXKA 5IPDA 1FITA 3OJ7A 4EQHA 1KPCA 2POFA 3O1CA 3L7XA 1ST4A
chains in the Genus database with same CATH topology
1ZWJA 4NJYA 5EMTA 1KPAA 6RHNA 5BV3A 4YKLB 3N1TA 4INCA 1Z84A 4EQEA 2H39A 3O1XA 1HXQA 4ZGLA 5CS2A 3R6FA 3BL9A 3SPDA 4EQGA 1HXPA 5RHNA 1Y23A 3I4SA 4NDGA 3I24A 3WO5A 3LB5A 4FITA 4QDVA 4NDIA 5IPCA 5IPBA 1KPFA 4RHNA 4NK0A 3SZQA 5ED3A 4INIA 1VLRA 1GUPA 4NJXA 3KSVA 4NDFA 2FITA 3ANOA 1XMLA 5IPEA 5IN3A 3N1SA 1KPEA 5I2EA 4ZKLA 4NJZA 3NRDA 3IMIA 3O1ZA 4QDEA 3QGZA 4EGUA 3RHNA 3OMFA 3TW2A 2Q4HA 4XBAA 4ZKVA 3SPLA 2FHIA 1RZYA 3P0TA 5FITA 2Q4LA 3O0MA 3OHEA 4NDHA 1KPBA 1XMMA 2OIKA 1EMSA 2EO4A 3BL7A 1FHIA 3FITA 1ST0A 6FITA 1AV5A 3BLAA 5ED6A 3SP4A 4QEBA 5I2FA 1GUQA 3OXKA 5IPDA 1FITA 3OJ7A 4EQHA 1KPCA 3O1CA 3L7XA 1ST4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZWJ A;  4NJY A;  5EMT A;  1KPA A;  6RHN A;  5BV3 A;  4YKL B;  3N1T A;  4INC A;  1Z84 A;  4EQE A;  2H39 A;  3O1X A;  1HXQ A;  4ZGL A;  5CS2 A;  3R6F A;  3BL9 A;  3SPD A;  4EQG A;  1HXP A;  5RHN A;  1Y23 A;  3I4S A;  4NDG A;  3I24 A;  3WO5 A;  3LB5 A;  4FIT A;  4QDV A;  4NDI A;  5IPC A;  5IPB A;  1KPF A;  4RHN A;  4NK0 A;  3SZQ A;  5ED3 A;  4INI A;  1VLR A;  1GUP A;  4NJX A;  3KSV A;  4NDF A;  2FIT A;  3ANO A;  1XML A;  5IPE A;  5IN3 A;  3N1S A;  1KPE A;  5I2E A;  4ZKL A;  4NJZ A;  3NRD A;  3IMI A;  3O1Z A;  4QDE A;  3QGZ A;  4EGU A;  3RHN A;  3OMF A;  3TW2 A;  2Q4H A;  4XBA A;  4ZKV A;  3SPL A;  2FHI A;  1RZY A;  3P0T A;  5FIT A;  2Q4L A;  3O0M A;  3OHE A;  4NDH A;  1KPB A;  1XMM A;  2OIK A;  1EMS A;  2EO4 A;  3BL7 A;  1FHI A;  3FIT A;  1ST0 A;  6FIT A;  1AV5 A;  3BLA A;  5ED6 A;  3SP4 A;  4QEB A;  5I2F A;  1GUQ A;  3OXK A;  5IPD A;  1FIT A;  3OJ7 A;  4EQH A;  1KPC A;  3O1C A;  3L7X A;  1ST4 A; 
#chains in the Genus database with same CATH topology
 1ZWJ A;  4NJY A;  5EMT A;  1KPA A;  6RHN A;  2GU0 A;  2R7C A;  5BV3 A;  4YKL B;  3N1T A;  4INC A;  1Z84 A;  4EQE A;  2H39 A;  3O1X A;  1HXQ A;  4ZGL A;  5CS2 A;  4I5V A;  3R6F A;  3BL9 A;  3SPD A;  4EQG A;  1HXP A;  5RHN A;  1Y23 A;  3I4S A;  4NDG A;  3I24 A;  3WO5 A;  4I5W A;  3LB5 A;  4FIT A;  4QDV A;  4NDI A;  5IPC A;  5IPB A;  1KPF A;  4RHN A;  4NK0 A;  3SZQ A;  5ED3 A;  4INI A;  1VLR A;  1GUP A;  4NJX A;  3KSV A;  4NDF A;  2FIT A;  3ANO A;  2LJW A;  1XML A;  4G0A A;  5IPE A;  5IN3 A;  2R7P A;  3N1S A;  1KPE A;  5I2E A;  2R8F A;  4ZKL A;  4NJZ A;  3NRD A;  3IMI A;  3O1Z A;  4QDE A;  3QGZ A;  4G0J A;  4EGU A;  3RHN A;  3OMF A;  3TW2 A;  2R7J A;  2Q4H A;  4XBA A;  4ZKV A;  3SPL A;  2FHI A;  1RZY A;  3P0T A;  5FIT A;  2Q4L A;  3O0M A;  3OHE A;  4NDH A;  1KPB A;  1XMM A;  2OIK A;  1EMS A;  2EO4 A;  3BL7 A;  1FHI A;  3FIT A;  1ST0 A;  6FIT A;  4I5T A;  1AV5 A;  3BLA A;  5ED6 A;  3SP4 A;  4QEB A;  5I2F A;  1GUQ A;  1L9V A;  3OXK A;  5IPD A;  1FIT A;  3OJ7 A;  4EQH A;  1KPC A;  2POF A;  3O1C A;  3L7X A;  1ST4 A; 
#chains in the Genus database with same CATH homology
 1ZWJ A;  4NJY A;  5EMT A;  1KPA A;  6RHN A;  5BV3 A;  4YKL B;  3N1T A;  4INC A;  1Z84 A;  4EQE A;  2H39 A;  3O1X A;  1HXQ A;  4ZGL A;  5CS2 A;  3R6F A;  3BL9 A;  3SPD A;  4EQG A;  1HXP A;  5RHN A;  1Y23 A;  3I4S A;  4NDG A;  3I24 A;  3WO5 A;  3LB5 A;  4FIT A;  4QDV A;  4NDI A;  5IPC A;  5IPB A;  1KPF A;  4RHN A;  4NK0 A;  3SZQ A;  5ED3 A;  4INI A;  1VLR A;  1GUP A;  4NJX A;  3KSV A;  4NDF A;  2FIT A;  3ANO A;  1XML A;  5IPE A;  5IN3 A;  3N1S A;  1KPE A;  5I2E A;  4ZKL A;  4NJZ A;  3NRD A;  3IMI A;  3O1Z A;  4QDE A;  3QGZ A;  4EGU A;  3RHN A;  3OMF A;  3TW2 A;  2Q4H A;  4XBA A;  4ZKV A;  3SPL A;  2FHI A;  1RZY A;  3P0T A;  5FIT A;  2Q4L A;  3O0M A;  3OHE A;  4NDH A;  1KPB A;  1XMM A;  2OIK A;  1EMS A;  2EO4 A;  3BL7 A;  1FHI A;  3FIT A;  1ST0 A;  6FIT A;  1AV5 A;  3BLA A;  5ED6 A;  3SP4 A;  4QEB A;  5I2F A;  1GUQ A;  3OXK A;  5IPD A;  1FIT A;  3OJ7 A;  4EQH A;  1KPC A;  3O1C A;  3L7X A;  1ST4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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