5EMTA

Human histidine triad nucleotide binding protein 1 (hhint1)-copper complex
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
116
structure length
116
Chain Sequence
ARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition by divalent metal ions of human histidine triad nucleotide binding protein1 (hHint1), a regulator of opioid analgesia and neuropathic pain.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Histidine triad nucleotide-binding protein 1
total genus 29
structure length 116
sequence length 116
chains with identical sequence B
ec nomenclature ec 3.-.-.-:
pdb deposition date 2015-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01230 HIT HIT domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.428.10 Alpha Beta 2-Layer Sandwich HIT family, subunit A HIT-like 5emtA00
3I4SA 1KPAA 1AV5A 1Z84A 3N1SA 4QDEA 3SPDA 3SP4A 5ED6A 1ZWJA 5ED3A 1EMSA 4NK0A 3I24A 3KSVA 3O1ZA 3WO5A 1KPFA 3R6FA 3ANOA 2FITA 1ST4A 3IMIA 4INCA 6RHNA 2EO4A 3P0TA 1FHIA 2Q4LA 3OXKA 4NDIA 5I2FA 3L7XA 4FITA 3RHNA 5IPDA 3TW2A 3O1XA 3OMFA 3SPLA 5CS2A 1GUQA 1KPBA 4EGUA 6FITA 2FHIA 4NDFA 4INIA 5FITA 3OHEA 4NJXA 5BV3A 4NDHA 4NJZA 1XMLA 4EQEA 3OJ7A 4QEBA 4NDGA 5IPBA 4EQGA 1Y23A 5IN3A 2Q4HA 3BLAA 3O0MA 1ST0A 4EQHA 4QDVA 3FITA 5IPEA 1XMMA 1HXPA 1RZYA 5I2EA 3N1TA 3SZQA 1GUPA 4ZKLA 1KPEA 3QGZA 4ZKVA 2OIKA 2H39A 3BL9A 3BL7A 4XBAA 4YKLB 3LB5A 5EMTA 1VLRA 4RHNA 1FITA 4ZGLA 1KPCA 3O1CA 1HXQA 4NJYA 3NRDA 5RHNA 5IPCA
chains in the Genus database with same CATH superfamily
3I4SA 2R7PA 1KPAA 1AV5A 1Z84A 3N1SA 4QDEA 3SPDA 3SP4A 5ED6A 1ZWJA 5ED3A 1EMSA 4I5TA 4NK0A 3I24A 3KSVA 3O1ZA 3WO5A 2POFA 1KPFA 3R6FA 3ANOA 2FITA 1ST4A 3IMIA 1L9VA 4INCA 6RHNA 2EO4A 3P0TA 1FHIA 2Q4LA 3OXKA 4I5VA 2R8FA 4G0JA 5I2FA 3L7XA 4NDIA 4FITA 3RHNA 5IPDA 3TW2A 3O1XA 3OMFA 3SPLA 4G0AA 2R7CA 4I5WA 5CS2A 1GUQA 1KPBA 4EGUA 6FITA 2FHIA 4NDFA 4INIA 5FITA 3OHEA 4NJXA 5BV3A 4NDHA 4NJZA 1XMLA 4EQEA 3OJ7A 4QEBA 4NDGA 5IPBA 4EQGA 1Y23A 5IN3A 2Q4HA 3BLAA 3O0MA 1ST0A 4EQHA 4QDVA 2R7JA 3FITA 5IPEA 1XMMA 2LJWA 1HXPA 1RZYA 5I2EA 3N1TA 3SZQA 1GUPA 4ZKLA 1KPEA 2GU0A 3QGZA 4ZKVA 2OIKA 2H39A 3BL9A 3BL7A 4XBAA 4YKLB 3LB5A 5EMTA 1VLRA 4RHNA 1FITA 4ZGLA 1KPCA 3O1CA 1HXQA 4NJYA 3NRDA 5RHNA 5IPCA
chains in the Genus database with same CATH topology
3I4SA 1KPAA 1AV5A 1Z84A 3N1SA 4QDEA 3SPDA 3SP4A 5ED6A 1ZWJA 5ED3A 1EMSA 4NK0A 3I24A 3KSVA 3O1ZA 3WO5A 1KPFA 3R6FA 3ANOA 2FITA 1ST4A 3IMIA 4INCA 6RHNA 2EO4A 3P0TA 1FHIA 2Q4LA 3OXKA 4NDIA 5I2FA 3L7XA 4FITA 3RHNA 5IPDA 3TW2A 3O1XA 3OMFA 3SPLA 5CS2A 1GUQA 1KPBA 4EGUA 6FITA 2FHIA 4NDFA 4INIA 5FITA 3OHEA 4NJXA 5BV3A 4NDHA 4NJZA 1XMLA 4EQEA 3OJ7A 4QEBA 4NDGA 5IPBA 4EQGA 1Y23A 5IN3A 2Q4HA 3BLAA 3O0MA 1ST0A 4EQHA 4QDVA 3FITA 5IPEA 1XMMA 1HXPA 1RZYA 5I2EA 3N1TA 3SZQA 1GUPA 4ZKLA 1KPEA 3QGZA 4ZKVA 2OIKA 2H39A 3BL9A 3BL7A 4XBAA 4YKLB 3LB5A 5EMTA 1VLRA 4RHNA 1FITA 4ZGLA 1KPCA 3O1CA 1HXQA 4NJYA 3NRDA 5RHNA 5IPCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4S A;  1KPA A;  1AV5 A;  1Z84 A;  3N1S A;  4QDE A;  3SPD A;  3SP4 A;  5ED6 A;  1ZWJ A;  5ED3 A;  1EMS A;  4NK0 A;  3I24 A;  3KSV A;  3O1Z A;  3WO5 A;  1KPF A;  3R6F A;  3ANO A;  2FIT A;  1ST4 A;  3IMI A;  4INC A;  6RHN A;  2EO4 A;  3P0T A;  1FHI A;  2Q4L A;  3OXK A;  4NDI A;  5I2F A;  3L7X A;  4FIT A;  3RHN A;  5IPD A;  3TW2 A;  3O1X A;  3OMF A;  3SPL A;  5CS2 A;  1GUQ A;  1KPB A;  4EGU A;  6FIT A;  2FHI A;  4NDF A;  4INI A;  5FIT A;  3OHE A;  4NJX A;  5BV3 A;  4NDH A;  4NJZ A;  1XML A;  4EQE A;  3OJ7 A;  4QEB A;  4NDG A;  5IPB A;  4EQG A;  1Y23 A;  5IN3 A;  2Q4H A;  3BLA A;  3O0M A;  1ST0 A;  4EQH A;  4QDV A;  3FIT A;  5IPE A;  1XMM A;  1HXP A;  1RZY A;  5I2E A;  3N1T A;  3SZQ A;  1GUP A;  4ZKL A;  1KPE A;  3QGZ A;  4ZKV A;  2OIK A;  2H39 A;  3BL9 A;  3BL7 A;  4XBA A;  4YKL B;  3LB5 A;  5EMT A;  1VLR A;  4RHN A;  1FIT A;  4ZGL A;  1KPC A;  3O1C A;  1HXQ A;  4NJY A;  3NRD A;  5RHN A;  5IPC A; 
#chains in the Genus database with same CATH topology
 3I4S A;  2R7P A;  1KPA A;  1AV5 A;  1Z84 A;  3N1S A;  4QDE A;  3SPD A;  3SP4 A;  5ED6 A;  1ZWJ A;  5ED3 A;  1EMS A;  4I5T A;  4NK0 A;  3I24 A;  3KSV A;  3O1Z A;  3WO5 A;  2POF A;  1KPF A;  3R6F A;  3ANO A;  2FIT A;  1ST4 A;  3IMI A;  1L9V A;  4INC A;  6RHN A;  2EO4 A;  3P0T A;  1FHI A;  2Q4L A;  3OXK A;  4I5V A;  2R8F A;  4G0J A;  5I2F A;  3L7X A;  4NDI A;  4FIT A;  3RHN A;  5IPD A;  3TW2 A;  3O1X A;  3OMF A;  3SPL A;  4G0A A;  2R7C A;  4I5W A;  5CS2 A;  1GUQ A;  1KPB A;  4EGU A;  6FIT A;  2FHI A;  4NDF A;  4INI A;  5FIT A;  3OHE A;  4NJX A;  5BV3 A;  4NDH A;  4NJZ A;  1XML A;  4EQE A;  3OJ7 A;  4QEB A;  4NDG A;  5IPB A;  4EQG A;  1Y23 A;  5IN3 A;  2Q4H A;  3BLA A;  3O0M A;  1ST0 A;  4EQH A;  4QDV A;  2R7J A;  3FIT A;  5IPE A;  1XMM A;  2LJW A;  1HXP A;  1RZY A;  5I2E A;  3N1T A;  3SZQ A;  1GUP A;  4ZKL A;  1KPE A;  2GU0 A;  3QGZ A;  4ZKV A;  2OIK A;  2H39 A;  3BL9 A;  3BL7 A;  4XBA A;  4YKL B;  3LB5 A;  5EMT A;  1VLR A;  4RHN A;  1FIT A;  4ZGL A;  1KPC A;  3O1C A;  1HXQ A;  4NJY A;  3NRD A;  5RHN A;  5IPC A; 
#chains in the Genus database with same CATH homology
 3I4S A;  1KPA A;  1AV5 A;  1Z84 A;  3N1S A;  4QDE A;  3SPD A;  3SP4 A;  5ED6 A;  1ZWJ A;  5ED3 A;  1EMS A;  4NK0 A;  3I24 A;  3KSV A;  3O1Z A;  3WO5 A;  1KPF A;  3R6F A;  3ANO A;  2FIT A;  1ST4 A;  3IMI A;  4INC A;  6RHN A;  2EO4 A;  3P0T A;  1FHI A;  2Q4L A;  3OXK A;  4NDI A;  5I2F A;  3L7X A;  4FIT A;  3RHN A;  5IPD A;  3TW2 A;  3O1X A;  3OMF A;  3SPL A;  5CS2 A;  1GUQ A;  1KPB A;  4EGU A;  6FIT A;  2FHI A;  4NDF A;  4INI A;  5FIT A;  3OHE A;  4NJX A;  5BV3 A;  4NDH A;  4NJZ A;  1XML A;  4EQE A;  3OJ7 A;  4QEB A;  4NDG A;  5IPB A;  4EQG A;  1Y23 A;  5IN3 A;  2Q4H A;  3BLA A;  3O0M A;  1ST0 A;  4EQH A;  4QDV A;  3FIT A;  5IPE A;  1XMM A;  1HXP A;  1RZY A;  5I2E A;  3N1T A;  3SZQ A;  1GUP A;  4ZKL A;  1KPE A;  3QGZ A;  4ZKV A;  2OIK A;  2H39 A;  3BL9 A;  3BL7 A;  4XBA A;  4YKL B;  3LB5 A;  5EMT A;  1VLR A;  4RHN A;  1FIT A;  4ZGL A;  1KPC A;  3O1C A;  1HXQ A;  4NJY A;  3NRD A;  5RHN A;  5IPC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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