1BOWA

Multidrug-binding domain of transcription activator bmrr (apo form)
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
158
structure length
143
Chain Sequence
RLGEVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIESNNSYGATFSFQPYTSIDEMTYRHIFTPVLISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIADRQLTVVSDVYELIIPIHYEYRVEMKIRIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
pubmed doi rcsb
molecule tags Transcription activator
source organism Bacillus subtilis
molecule keywords MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR
total genus 26
structure length 143
sequence length 158
ec nomenclature
pdb deposition date 1998-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 1bowA00
3E0HA 2BOWA 3R8KA 5KAWA 5KAVA 3D71A 5KAUA 1EXIA 3IAOA 4AYZA 1R8EA 5KAXA 3Q5SA 2HVAA 4B0YA 5KCBA 1JYHA 1EXJA 3D6ZA 3Q5RA 1BOWA 2KCUA 3D6YA 4A1MA 5GQQA 3B49A 2GOVA 5KATA 3GK6A 3Q5PA 3Q2YA 3R8JA 3D70A 1D5YA 3Q1MA 3Q3DA 4AYZB 3LURA
chains in the Genus database with same CATH superfamily
3E0HA 2BOWA 3R8KA 5KAWA 5KAVA 3D71A 5KAUA 1EXIA 3IAOA 4AYZA 1R8EA 5KAXA 3Q5SA 2HVAA 4B0YA 5KCBA 1JYHA 1EXJA 3D6ZA 3Q5RA 1BOWA 2KCUA 3D6YA 4A1MA 5GQQA 3B49A 2GOVA 5KATA 3GK6A 3Q5PA 3Q2YA 3R8JA 3D70A 1D5YA 3Q1MA 3Q3DA 4AYZB 3LURA
chains in the Genus database with same CATH topology
3E0HA 2BOWA 3R8KA 5KAWA 5KAVA 3D71A 5KAUA 1EXIA 3IAOA 4AYZA 1R8EA 5KAXA 3Q5SA 2HVAA 4B0YA 5KCBA 1JYHA 1EXJA 3D6ZA 3Q5RA 1BOWA 2KCUA 3D6YA 4A1MA 5GQQA 3B49A 2GOVA 5KATA 3GK6A 3Q5PA 3Q2YA 3R8JA 3D70A 1D5YA 3Q1MA 3Q3DA 4AYZB 3LURA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3E0H A;  2BOW A;  3R8K A;  5KAW A;  5KAV A;  3D71 A;  5KAU A;  1EXI A;  3IAO A;  4AYZ A;  1R8E A;  5KAX A;  3Q5S A;  2HVA A;  4B0Y A;  5KCB A;  1JYH A;  1EXJ A;  3D6Z A;  3Q5R A;  1BOW A;  2KCU A;  3D6Y A;  4A1M A;  5GQQ A;  3B49 A;  2GOV A;  5KAT A;  3GK6 A;  3Q5P A;  3Q2Y A;  3R8J A;  3D70 A;  1D5Y A;  3Q1M A;  3Q3D A;  4AYZ B;  3LUR A; 
#chains in the Genus database with same CATH topology
 3E0H A;  2BOW A;  3R8K A;  5KAW A;  5KAV A;  3D71 A;  5KAU A;  1EXI A;  3IAO A;  4AYZ A;  1R8E A;  5KAX A;  3Q5S A;  2HVA A;  4B0Y A;  5KCB A;  1JYH A;  1EXJ A;  3D6Z A;  3Q5R A;  1BOW A;  2KCU A;  3D6Y A;  4A1M A;  5GQQ A;  3B49 A;  2GOV A;  5KAT A;  3GK6 A;  3Q5P A;  3Q2Y A;  3R8J A;  3D70 A;  1D5Y A;  3Q1M A;  3Q3D A;  4AYZ B;  3LUR A; 
#chains in the Genus database with same CATH homology
 3E0H A;  2BOW A;  3R8K A;  5KAW A;  5KAV A;  3D71 A;  5KAU A;  1EXI A;  3IAO A;  4AYZ A;  1R8E A;  5KAX A;  3Q5S A;  2HVA A;  4B0Y A;  5KCB A;  1JYH A;  1EXJ A;  3D6Z A;  3Q5R A;  1BOW A;  2KCU A;  3D6Y A;  4A1M A;  5GQQ A;  3B49 A;  2GOV A;  5KAT A;  3GK6 A;  3Q5P A;  3Q2Y A;  3R8J A;  3D70 A;  1D5Y A;  3Q1M A;  3Q3D A;  4AYZ B;  3LUR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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