5KAWA

The structure of sav2435 bound to tetraphenylphosphonium and rhodamine 6g
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
165
structure length
165
Chain Sequence
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIAKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQANTVKSAPFFELYQDGDTTSEKYITEIWMPVKGLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Unknown function
molecule keywords SA2223 protein
publication title Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
pubmed doi rcsb
source organism Staphylococcus aureus (strain n315)
total genus 44
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2016-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 5kawA00
5KAXA 3D71A 3Q5SA 1EXIA 5GQQA 2KCUA 1EXJA 3E0HA 5KCBA 3Q5PA 3LURA 3D6YA 3IAOA 2BOWA 4AYZA 5KAUA 5KAVA 3R8KA 4B0YA 1D5YA 4AYZB 2GOVA 1JYHA 3B49A 4A1MA 3Q1MA 3Q5RA 1R8EA 5KAWA 1BOWA 2HVAA 3Q2YA 3Q3DA 3D6ZA 3R8JA 3D70A 3GK6A 5KATA
chains in the Genus database with same CATH superfamily
5KAXA 3D71A 3Q5SA 1EXIA 5GQQA 2KCUA 1EXJA 3E0HA 5KCBA 3Q5PA 3LURA 3D6YA 3IAOA 2BOWA 4AYZA 5KAUA 5KAVA 3R8KA 4B0YA 1D5YA 4AYZB 2GOVA 1JYHA 3B49A 4A1MA 3Q1MA 3Q5RA 1R8EA 5KAWA 1BOWA 2HVAA 3Q2YA 3Q3DA 3D6ZA 3R8JA 3D70A 3GK6A 5KATA
chains in the Genus database with same CATH topology
5KAXA 3D71A 3Q5SA 1EXIA 5GQQA 2KCUA 1EXJA 3E0HA 5KCBA 3Q5PA 3LURA 3D6YA 3IAOA 2BOWA 4AYZA 5KAUA 5KAVA 3R8KA 4B0YA 1D5YA 4AYZB 2GOVA 1JYHA 3B49A 4A1MA 3Q1MA 3Q5RA 1R8EA 5KAWA 1BOWA 2HVAA 3Q2YA 3Q3DA 3D6ZA 3R8JA 3D70A 3GK6A 5KATA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KAX A;  3D71 A;  3Q5S A;  1EXI A;  5GQQ A;  2KCU A;  1EXJ A;  3E0H A;  5KCB A;  3Q5P A;  3LUR A;  3D6Y A;  3IAO A;  2BOW A;  4AYZ A;  5KAU A;  5KAV A;  3R8K A;  4B0Y A;  1D5Y A;  4AYZ B;  2GOV A;  1JYH A;  3B49 A;  4A1M A;  3Q1M A;  3Q5R A;  1R8E A;  5KAW A;  1BOW A;  2HVA A;  3Q2Y A;  3Q3D A;  3D6Z A;  3R8J A;  3D70 A;  3GK6 A;  5KAT A; 
#chains in the Genus database with same CATH topology
 5KAX A;  3D71 A;  3Q5S A;  1EXI A;  5GQQ A;  2KCU A;  1EXJ A;  3E0H A;  5KCB A;  3Q5P A;  3LUR A;  3D6Y A;  3IAO A;  2BOW A;  4AYZ A;  5KAU A;  5KAV A;  3R8K A;  4B0Y A;  1D5Y A;  4AYZ B;  2GOV A;  1JYH A;  3B49 A;  4A1M A;  3Q1M A;  3Q5R A;  1R8E A;  5KAW A;  1BOW A;  2HVA A;  3Q2Y A;  3Q3D A;  3D6Z A;  3R8J A;  3D70 A;  3GK6 A;  5KAT A; 
#chains in the Genus database with same CATH homology
 5KAX A;  3D71 A;  3Q5S A;  1EXI A;  5GQQ A;  2KCU A;  1EXJ A;  3E0H A;  5KCB A;  3Q5P A;  3LUR A;  3D6Y A;  3IAO A;  2BOW A;  4AYZ A;  5KAU A;  5KAV A;  3R8K A;  4B0Y A;  1D5Y A;  4AYZ B;  2GOV A;  1JYH A;  3B49 A;  4A1M A;  3Q1M A;  3Q5R A;  1R8E A;  5KAW A;  1BOW A;  2HVA A;  3Q2Y A;  3Q3D A;  3D6Z A;  3R8J A;  3D70 A;  3GK6 A;  5KAT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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