5KAWA

The structure of sav2435 bound to tetraphenylphosphonium and rhodamine 6g
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
165
structure length
165
Chain Sequence
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCIPELDGKMSYMIAVTGDNSADIAKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQANTVKSAPFFELYQDGDTTSEKYITEIWMPVKGLEHHHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution Binding and Structural Analyses Reveal Potential Multidrug Resistance Functions for SAV2435 and CTR107 and Other GyrI-like Proteins.
pubmed doi rcsb
molecule tags Unknown function
source organism Staphylococcus aureus (strain n315)
molecule keywords SA2223 protein
total genus 44
structure length 165
sequence length 165
ec nomenclature
pdb deposition date 2016-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF06445 GyrI-like GyrI-like small molecule binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.20.80.10 Alpha Beta Alpha-Beta Barrel Multidrug-efflux Transporter 1 Regulator Bmrr; Chain A Regulatory factor, effector binding domain 5kawA00
1EXIA 3Q1MA 5KATA 3Q3DA 2HVAA 5KAUA 3Q5RA 1EXJA 1D5YA 2BOWA 3GK6A 3LURA 5KAWA 3IAOA 1BOWA 2KCUA 5KAXA 3B49A 4AYZB 3E0HA 4B0YA 5KCBA 3D70A 4AYZA 3D6ZA 1JYHA 3D6YA 1R8EA 3R8KA 2GOVA 4A1MA 3R8JA 3Q2YA 3Q5PA 3D71A 3Q5SA 5GQQA 5KAVA
chains in the Genus database with same CATH superfamily
1EXIA 3Q1MA 5KATA 3Q3DA 2HVAA 5KAUA 3Q5RA 1EXJA 1D5YA 2BOWA 3GK6A 3LURA 5KAWA 3IAOA 1BOWA 2KCUA 5KAXA 3B49A 4AYZB 3E0HA 4B0YA 5KCBA 3D70A 4AYZA 3D6ZA 1JYHA 3D6YA 1R8EA 3R8KA 2GOVA 4A1MA 3R8JA 3Q2YA 3Q5PA 3D71A 3Q5SA 5GQQA 5KAVA
chains in the Genus database with same CATH topology
1EXIA 3Q1MA 5KATA 3Q3DA 2HVAA 5KAUA 3Q5RA 1EXJA 1D5YA 2BOWA 3GK6A 3LURA 5KAWA 3IAOA 1BOWA 2KCUA 5KAXA 3B49A 4AYZB 3E0HA 4B0YA 5KCBA 3D70A 4AYZA 3D6ZA 1JYHA 3D6YA 1R8EA 3R8KA 2GOVA 4A1MA 3R8JA 3Q2YA 3Q5PA 3D71A 3Q5SA 5GQQA 5KAVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EXI A;  3Q1M A;  5KAT A;  3Q3D A;  2HVA A;  5KAU A;  3Q5R A;  1EXJ A;  1D5Y A;  2BOW A;  3GK6 A;  3LUR A;  5KAW A;  3IAO A;  1BOW A;  2KCU A;  5KAX A;  3B49 A;  4AYZ B;  3E0H A;  4B0Y A;  5KCB A;  3D70 A;  4AYZ A;  3D6Z A;  1JYH A;  3D6Y A;  1R8E A;  3R8K A;  2GOV A;  4A1M A;  3R8J A;  3Q2Y A;  3Q5P A;  3D71 A;  3Q5S A;  5GQQ A;  5KAV A; 
#chains in the Genus database with same CATH topology
 1EXI A;  3Q1M A;  5KAT A;  3Q3D A;  2HVA A;  5KAU A;  3Q5R A;  1EXJ A;  1D5Y A;  2BOW A;  3GK6 A;  3LUR A;  5KAW A;  3IAO A;  1BOW A;  2KCU A;  5KAX A;  3B49 A;  4AYZ B;  3E0H A;  4B0Y A;  5KCB A;  3D70 A;  4AYZ A;  3D6Z A;  1JYH A;  3D6Y A;  1R8E A;  3R8K A;  2GOV A;  4A1M A;  3R8J A;  3Q2Y A;  3Q5P A;  3D71 A;  3Q5S A;  5GQQ A;  5KAV A; 
#chains in the Genus database with same CATH homology
 1EXI A;  3Q1M A;  5KAT A;  3Q3D A;  2HVA A;  5KAU A;  3Q5R A;  1EXJ A;  1D5Y A;  2BOW A;  3GK6 A;  3LUR A;  5KAW A;  3IAO A;  1BOW A;  2KCU A;  5KAX A;  3B49 A;  4AYZ B;  3E0H A;  4B0Y A;  5KCB A;  3D70 A;  4AYZ A;  3D6Z A;  1JYH A;  3D6Y A;  1R8E A;  3R8K A;  2GOV A;  4A1M A;  3R8J A;  3Q2Y A;  3Q5P A;  3D71 A;  3Q5S A;  5GQQ A;  5KAV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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