1BQTA

Three-dimensional structure of human insulin-like growth factor-i (igf-i) determined by 1h-nmr and distance geometry, 6 structures
Total Genus 3
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
3
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR-I
publication title Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
pubmed rcsb
source organism Homo sapiens
total genus 3
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1998-08-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1bqtA00
1SJUA 2DSQC 1H02B 3GF1A 1B9GA 6INSE 1GZRB 1GZZB 1EFEA 5L3LA 1PMXA 2JZQA 2DSPI 2GF1A 1IMXA 2KQPA 2LWZA 1TGRA 4XSSB 1BQTA 5L3MA 2L29B 2KJIA 1GZYB 1ZEIA 3KR3D 1IGLA 2DSRI 5L3NA 3LRIA 1H59A 1WQJI
chains in the Genus database with same CATH superfamily
1SJUA 3F2BA 2DSQC 1H02B 3GF1A 3F2DA 3F2CA 1B9GA 6INSE 1GZRB 2L14B 1GZZB 1EFEA 5L3LA 1PMXA 2JZQA 2DSPI 2GF1A 1IMXA 2KQPA 2LWZA 1TGRA 4XSSB 1BQTA 5L3MA 2L29B 2KJIA 1GZYB 1ZEIA 3KR3D 1IGLA 2DSRI 5L3NA 3LRIA 1H59A 1WQJI
chains in the Genus database with same CATH topology
1SJUA 2DSQC 1H02B 3GF1A 1B9GA 6INSE 1GZRB 1GZZB 1EFEA 5L3LA 1PMXA 2JZQA 2DSPI 2GF1A 1IMXA 2KQPA 2LWZA 1TGRA 4XSSB 1BQTA 5L3MA 2L29B 2KJIA 1GZYB 1ZEIA 3KR3D 1IGLA 2DSRI 5L3NA 3LRIA 1H59A 1WQJI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SJU A;  2DSQ C;  1H02 B;  3GF1 A;  1B9G A;  6INS E;  1GZR B;  1GZZ B;  1EFE A;  5L3L A;  1PMX A;  2JZQ A;  2DSP I;  2GF1 A;  1IMX A;  2KQP A;  2LWZ A;  1TGR A;  4XSS B;  1BQT A;  5L3M A;  2L29 B;  2KJI A;  1GZY B;  1ZEI A;  3KR3 D;  1IGL A;  2DSR I;  5L3N A;  3LRI A;  1H59 A;  1WQJ I; 
#chains in the Genus database with same CATH topology
 1SJU A;  3F2B A;  2DSQ C;  1H02 B;  3GF1 A;  3F2D A;  3F2C A;  1B9G A;  6INS E;  1GZR B;  2L14 B;  1GZZ B;  1EFE A;  5L3L A;  1PMX A;  2JZQ A;  2DSP I;  2GF1 A;  1IMX A;  2KQP A;  2LWZ A;  1TGR A;  4XSS B;  1BQT A;  5L3M A;  2L29 B;  2KJI A;  1GZY B;  1ZEI A;  3KR3 D;  1IGL A;  2DSR I;  5L3N A;  3LRI A;  1H59 A;  1WQJ I; 
#chains in the Genus database with same CATH homology
 1SJU A;  2DSQ C;  1H02 B;  3GF1 A;  1B9G A;  6INS E;  1GZR B;  1GZZ B;  1EFE A;  5L3L A;  1PMX A;  2JZQ A;  2DSP I;  2GF1 A;  1IMX A;  2KQP A;  2LWZ A;  1TGR A;  4XSS B;  1BQT A;  5L3M A;  2L29 B;  2KJI A;  1GZY B;  1ZEI A;  3KR3 D;  1IGL A;  2DSR I;  5L3N A;  3LRI A;  1H59 A;  1WQJ I; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...