The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
337
|
sequence length |
1024
|
structure length |
993
|
Chain Sequence |
VRRLETIVEEERRVVVQGYVFDAEVSELKSGRTLLTMKITDYTNSILVKMFSRDKEDAELMSGVKKGMWVKVRGSVQNDTFVRDLVIIANDLNEIAANERQDTAPEGEKRVELHLHTPMSQMDAVTSVTKLIEQAKKWGHPAIAVTDHAVVQSFPEAYSAAKKHGMKVIYGLEANIVDDPFHVTLLAQNETGLKNLFKLVSLSHIQYFHRVPRIPRSVLVKHRDGLLVGSGCDKGELFDNVEDIARFYDFLEVHPPDVYKPLVKDEEMIKNIIRSIVALGEKLDIPVVATGNVHYLNPEDKIYRKILIHSQGGANPLNRHELPDVYFRTTNEMLDCFSFLGPEKAKEIVVDNTQKIASLIGDVKPIKDELYTPRIEGADEEIREMSYRRAKEIYGDPLPKLVEERLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYVCPNCKHSEFFNDGSVGSGFDLPDKNCPRCGTKYKKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKVLFGEDNVYRAGTIGTVADKTAYGFVKAYASDHNLELRGAEIDRLAAGCTGVKRTTGQHPGGIIVVPDYMEIYDFTPIQYPADDTSSEWRTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPDVMGIFSSTEPLGVTPEQIMCNVGTIGIPEFGTRFVRQMLEETRPKTFSELVQISGLSHGTDVWLGNAQELIQNGTCTLSEVIGCRDDIMVYLIYRGLEPSLAFKIMESVRKGKGLTPEFEAEMRKHDVPEWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYASYFTVRAEDFDLDAMIKGSAAIRKRIEEINAKGIQATAKEKSLLTVLEVALEMCERGFSFKNIDLYRSQATEFVIDGNSLIPPFNAIPGLGTNVAQAIVRAREEGEFLSKEDLQQRGKLSKTLLEYLESRGCLDSLPDHNQLSLF
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structure of PolC reveals unique DNA binding and fidelity determinants.
pubmed doi rcsb |
| source organism |
Geobacillus kaustophilus
|
| molecule tags |
Transferase/dna
|
| molecule keywords |
GEOBACILLUS KAUSTOPHILUS DNA POLC
|
| total genus |
337
|
| structure length |
993
|
| sequence length |
1024
|
| ec nomenclature |
ec
2.7.7.7: DNA-directed DNA polymerase. |
| pdb deposition date | 2008-10-29 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02811 | PHP | PHP domain |
| A | PF07733 | DNA_pol3_alpha | Bacterial DNA polymerase III alpha NTPase domain |
| A | PF14579 | HHH_6 | Helix-hairpin-helix motif |
| A | PF17657 | DNA_pol3_finger | Bacterial DNA polymerase III alpha subunit finger domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Insulin-like, subunit E | Insulin-like, subunit E | ||
| Mainly Alpha | Orthogonal Bundle | DNA polymerase; domain 1 | DNA polymerase; domain 1 | ||
| Mainly Alpha | Orthogonal Bundle | DNA polymerase; domain 1 | DNA polymerase; domain 1 | ||
| Mainly Beta | Beta Barrel | OB fold (Dihydrolipoamide Acetyltransferase, E2P) | Nucleic acid-binding proteins | ||
| Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Metal-dependent hydrolases | ||
| Alpha Beta | 2-Layer Sandwich | glyoxalase-related enzyme like fold | glyoxalase-related enzyme like fold |
