5L3MA

D11 bound [s39_pq]-igf-ii
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
69
structure length
69
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSPQRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords Insulin-like growth factor II
publication title Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.
pubmed doi rcsb
source organism Homo sapiens
total genus 18
structure length 69
sequence length 69
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 5l3mA00
1PMXA 1TGRA 1ZEIA 1GZZB 4XSSB 5L3MA 2L29B 1GZRB 2DSPI 2GF1A 2JZQA 6INSE 5L3NA 2KQPA 1EFEA 1WQJI 2DSRI 3LRIA 1IMXA 1SJUA 1B9GA 1GZYB 2DSQC 1H59A 1H02B 3GF1A 1IGLA 1BQTA 3KR3D 2LWZA 5L3LA 2KJIA
chains in the Genus database with same CATH superfamily
1PMXA 1TGRA 1ZEIA 1GZZB 4XSSB 5L3MA 2L29B 1GZRB 2DSPI 2GF1A 2JZQA 6INSE 5L3NA 2KQPA 3F2DA 1EFEA 1WQJI 2DSRI 3LRIA 1IMXA 1SJUA 1B9GA 3F2BA 1GZYB 2DSQC 1H59A 1H02B 2L14B 3GF1A 1IGLA 1BQTA 3F2CA 3KR3D 2LWZA 5L3LA 2KJIA
chains in the Genus database with same CATH topology
1PMXA 1TGRA 1ZEIA 1GZZB 4XSSB 5L3MA 2L29B 1GZRB 2DSPI 2GF1A 2JZQA 6INSE 5L3NA 2KQPA 1EFEA 1WQJI 2DSRI 3LRIA 1IMXA 1SJUA 1B9GA 1GZYB 2DSQC 1H59A 1H02B 3GF1A 1IGLA 1BQTA 3KR3D 2LWZA 5L3LA 2KJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PMX A;  1TGR A;  1ZEI A;  1GZZ B;  4XSS B;  5L3M A;  2L29 B;  1GZR B;  2DSP I;  2GF1 A;  2JZQ A;  6INS E;  5L3N A;  2KQP A;  1EFE A;  1WQJ I;  2DSR I;  3LRI A;  1IMX A;  1SJU A;  1B9G A;  1GZY B;  2DSQ C;  1H59 A;  1H02 B;  3GF1 A;  1IGL A;  1BQT A;  3KR3 D;  2LWZ A;  5L3L A;  2KJI A; 
#chains in the Genus database with same CATH topology
 1PMX A;  1TGR A;  1ZEI A;  1GZZ B;  4XSS B;  5L3M A;  2L29 B;  1GZR B;  2DSP I;  2GF1 A;  2JZQ A;  6INS E;  5L3N A;  2KQP A;  3F2D A;  1EFE A;  1WQJ I;  2DSR I;  3LRI A;  1IMX A;  1SJU A;  1B9G A;  3F2B A;  1GZY B;  2DSQ C;  1H59 A;  1H02 B;  2L14 B;  3GF1 A;  1IGL A;  1BQT A;  3F2C A;  3KR3 D;  2LWZ A;  5L3L A;  2KJI A; 
#chains in the Genus database with same CATH homology
 1PMX A;  1TGR A;  1ZEI A;  1GZZ B;  4XSS B;  5L3M A;  2L29 B;  1GZR B;  2DSP I;  2GF1 A;  2JZQ A;  6INS E;  5L3N A;  2KQP A;  1EFE A;  1WQJ I;  2DSR I;  3LRI A;  1IMX A;  1SJU A;  1B9G A;  1GZY B;  2DSQ C;  1H59 A;  1H02 B;  3GF1 A;  1IGL A;  1BQT A;  3KR3 D;  2LWZ A;  5L3L A;  2KJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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