1H02B

Human insulin-like growth factor; srs daresbury data
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
64
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSAPQTGIVDECCFRSCDLRRLEMYCAPLKPAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
source organism Homo sapiens
total genus 12
structure length 64
sequence length 66
ec nomenclature
pdb deposition date 2002-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1h02B00
1IMXA 1EFEA 1H02B 1H59A 2KQPA 3LRIA 2JZQA 1SJUA 6INSE 1IGLA 5L3MA 2GF1A 1TGRA 4XSSB 2LWZA 1BQTA 2DSRI 1PMXA 1GZZB 5L3NA 5L3LA 2KJIA 2DSPI 2L29B 1GZYB 1GZRB 1ZEIA 2DSQC 3GF1A 1B9GA 3KR3D 1WQJI
chains in the Genus database with same CATH superfamily
1IMXA 1EFEA 1H02B 1H59A 2KQPA 3F2CA 3LRIA 3F2DA 2JZQA 1SJUA 6INSE 1IGLA 5L3MA 2GF1A 1TGRA 4XSSB 2LWZA 1BQTA 2DSRI 1PMXA 1GZZB 5L3NA 5L3LA 2KJIA 2DSPI 2L29B 1GZYB 3F2BA 1GZRB 1ZEIA 2DSQC 3GF1A 2L14B 1B9GA 3KR3D 1WQJI
chains in the Genus database with same CATH topology
1IMXA 1EFEA 1H02B 1H59A 2KQPA 3LRIA 2JZQA 1SJUA 6INSE 1IGLA 5L3MA 2GF1A 1TGRA 4XSSB 2LWZA 1BQTA 2DSRI 1PMXA 1GZZB 5L3NA 5L3LA 2KJIA 2DSPI 2L29B 1GZYB 1GZRB 1ZEIA 2DSQC 3GF1A 1B9GA 3KR3D 1WQJI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IMX A;  1EFE A;  1H02 B;  1H59 A;  2KQP A;  3LRI A;  2JZQ A;  1SJU A;  6INS E;  1IGL A;  5L3M A;  2GF1 A;  1TGR A;  4XSS B;  2LWZ A;  1BQT A;  2DSR I;  1PMX A;  1GZZ B;  5L3N A;  5L3L A;  2KJI A;  2DSP I;  2L29 B;  1GZY B;  1GZR B;  1ZEI A;  2DSQ C;  3GF1 A;  1B9G A;  3KR3 D;  1WQJ I; 
#chains in the Genus database with same CATH topology
 1IMX A;  1EFE A;  1H02 B;  1H59 A;  2KQP A;  3F2C A;  3LRI A;  3F2D A;  2JZQ A;  1SJU A;  6INS E;  1IGL A;  5L3M A;  2GF1 A;  1TGR A;  4XSS B;  2LWZ A;  1BQT A;  2DSR I;  1PMX A;  1GZZ B;  5L3N A;  5L3L A;  2KJI A;  2DSP I;  2L29 B;  1GZY B;  3F2B A;  1GZR B;  1ZEI A;  2DSQ C;  3GF1 A;  2L14 B;  1B9G A;  3KR3 D;  1WQJ I; 
#chains in the Genus database with same CATH homology
 1IMX A;  1EFE A;  1H02 B;  1H59 A;  2KQP A;  3LRI A;  2JZQ A;  1SJU A;  6INS E;  1IGL A;  5L3M A;  2GF1 A;  1TGR A;  4XSS B;  2LWZ A;  1BQT A;  2DSR I;  1PMX A;  1GZZ B;  5L3N A;  5L3L A;  2KJI A;  2DSP I;  2L29 B;  1GZY B;  1GZR B;  1ZEI A;  2DSQ C;  3GF1 A;  1B9G A;  3KR3 D;  1WQJ I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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