1GZZB

Human insulin-like growth factor; hamburg data
Total Genus 11
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
66
structure length
60
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYAPQTGIVDECCFRSCDLRRLEMYCAPLKP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
source organism Homo sapiens
total genus 11
structure length 60
sequence length 66
ec nomenclature
pdb deposition date 2002-06-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1gzzB00
5L3NA 1BQTA 3GF1A 3KR3D 2KJIA 1TGRA 1GZRB 5L3MA 1IMXA 1GZYB 1ZEIA 2DSPI 1EFEA 1WQJI 2JZQA 4XSSB 2L29B 2DSQC 1H02B 1PMXA 6INSE 3LRIA 2KQPA 1GZZB 2GF1A 2DSRI 2LWZA 5L3LA 1IGLA 1SJUA 1B9GA 1H59A
chains in the Genus database with same CATH superfamily
5L3NA 1BQTA 3GF1A 3KR3D 2KJIA 1TGRA 1GZRB 5L3MA 3F2BA 2L14B 1IMXA 1GZYB 1ZEIA 2DSPI 1EFEA 1WQJI 3F2CA 2JZQA 4XSSB 2L29B 2DSQC 1H02B 1PMXA 6INSE 3LRIA 2KQPA 1GZZB 2GF1A 2DSRI 2LWZA 5L3LA 1IGLA 1SJUA 3F2DA 1B9GA 1H59A
chains in the Genus database with same CATH topology
5L3NA 1BQTA 3GF1A 3KR3D 2KJIA 1TGRA 1GZRB 5L3MA 1IMXA 1GZYB 1ZEIA 2DSPI 1EFEA 1WQJI 2JZQA 4XSSB 2L29B 2DSQC 1H02B 1PMXA 6INSE 3LRIA 2KQPA 1GZZB 2GF1A 2DSRI 2LWZA 5L3LA 1IGLA 1SJUA 1B9GA 1H59A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L3N A;  1BQT A;  3GF1 A;  3KR3 D;  2KJI A;  1TGR A;  1GZR B;  5L3M A;  1IMX A;  1GZY B;  1ZEI A;  2DSP I;  1EFE A;  1WQJ I;  2JZQ A;  4XSS B;  2L29 B;  2DSQ C;  1H02 B;  1PMX A;  6INS E;  3LRI A;  2KQP A;  1GZZ B;  2GF1 A;  2DSR I;  2LWZ A;  5L3L A;  1IGL A;  1SJU A;  1B9G A;  1H59 A; 
#chains in the Genus database with same CATH topology
 5L3N A;  1BQT A;  3GF1 A;  3KR3 D;  2KJI A;  1TGR A;  1GZR B;  5L3M A;  3F2B A;  2L14 B;  1IMX A;  1GZY B;  1ZEI A;  2DSP I;  1EFE A;  1WQJ I;  3F2C A;  2JZQ A;  4XSS B;  2L29 B;  2DSQ C;  1H02 B;  1PMX A;  6INS E;  3LRI A;  2KQP A;  1GZZ B;  2GF1 A;  2DSR I;  2LWZ A;  5L3L A;  1IGL A;  1SJU A;  3F2D A;  1B9G A;  1H59 A; 
#chains in the Genus database with same CATH homology
 5L3N A;  1BQT A;  3GF1 A;  3KR3 D;  2KJI A;  1TGR A;  1GZR B;  5L3M A;  1IMX A;  1GZY B;  1ZEI A;  2DSP I;  1EFE A;  1WQJ I;  2JZQ A;  4XSS B;  2L29 B;  2DSQ C;  1H02 B;  1PMX A;  6INS E;  3LRI A;  2KQP A;  1GZZ B;  2GF1 A;  2DSR I;  2LWZ A;  5L3L A;  1IGL A;  1SJU A;  1B9G A;  1H59 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...