3GF1A

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 1991-01-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 3gf1A00
1BQTA 1H02B 5L3MA 2GF1A 5L3LA 1GZZB 1GZRB 1EFEA 1SJUA 2LWZA 1IGLA 1IMXA 4XSSB 2JZQA 1H59A 5L3NA 3LRIA 2DSPI 1GZYB 1B9GA 1TGRA 3KR3D 1WQJI 1ZEIA 2L29B 2KQPA 3GF1A 1PMXA 6INSE 2DSRI 2KJIA 2DSQC
chains in the Genus database with same CATH superfamily
1BQTA 2L14B 1H02B 5L3MA 2GF1A 5L3LA 1GZZB 1GZRB 1EFEA 3F2CA 1SJUA 2LWZA 1IGLA 1IMXA 4XSSB 2JZQA 1H59A 5L3NA 3F2BA 3LRIA 2DSPI 1GZYB 3F2DA 1B9GA 1TGRA 3KR3D 1WQJI 1ZEIA 2L29B 2KQPA 3GF1A 1PMXA 6INSE 2DSRI 2KJIA 2DSQC
chains in the Genus database with same CATH topology
1BQTA 1H02B 5L3MA 2GF1A 5L3LA 1GZZB 1GZRB 1EFEA 1SJUA 2LWZA 1IGLA 1IMXA 4XSSB 2JZQA 1H59A 5L3NA 3LRIA 2DSPI 1GZYB 1B9GA 1TGRA 3KR3D 1WQJI 1ZEIA 2L29B 2KQPA 3GF1A 1PMXA 6INSE 2DSRI 2KJIA 2DSQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BQT A;  1H02 B;  5L3M A;  2GF1 A;  5L3L A;  1GZZ B;  1GZR B;  1EFE A;  1SJU A;  2LWZ A;  1IGL A;  1IMX A;  4XSS B;  2JZQ A;  1H59 A;  5L3N A;  3LRI A;  2DSP I;  1GZY B;  1B9G A;  1TGR A;  3KR3 D;  1WQJ I;  1ZEI A;  2L29 B;  2KQP A;  3GF1 A;  1PMX A;  6INS E;  2DSR I;  2KJI A;  2DSQ C; 
#chains in the Genus database with same CATH topology
 1BQT A;  2L14 B;  1H02 B;  5L3M A;  2GF1 A;  5L3L A;  1GZZ B;  1GZR B;  1EFE A;  3F2C A;  1SJU A;  2LWZ A;  1IGL A;  1IMX A;  4XSS B;  2JZQ A;  1H59 A;  5L3N A;  3F2B A;  3LRI A;  2DSP I;  1GZY B;  3F2D A;  1B9G A;  1TGR A;  3KR3 D;  1WQJ I;  1ZEI A;  2L29 B;  2KQP A;  3GF1 A;  1PMX A;  6INS E;  2DSR I;  2KJI A;  2DSQ C; 
#chains in the Genus database with same CATH homology
 1BQT A;  1H02 B;  5L3M A;  2GF1 A;  5L3L A;  1GZZ B;  1GZR B;  1EFE A;  1SJU A;  2LWZ A;  1IGL A;  1IMX A;  4XSS B;  2JZQ A;  1H59 A;  5L3N A;  3LRI A;  2DSP I;  1GZY B;  1B9G A;  1TGR A;  3KR3 D;  1WQJ I;  1ZEI A;  2L29 B;  2KQP A;  3GF1 A;  1PMX A;  6INS E;  2DSR I;  2KJI A;  2DSQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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