1GZRB

Human insulin-like growth factor; esrf data
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
64
structure length
61
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSPQTGIVDECCFRSCDLRRLEMYCAPLKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Growth factor
molecule keywords INSULIN-LIKE GROWTH FACTOR I
publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
source organism Homo sapiens
total genus 14
structure length 61
sequence length 64
ec nomenclature
pdb deposition date 2002-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1gzrB00
2L29B 5L3MA 2LWZA 1IMXA 2KQPA 2JZQA 1WQJI 1SJUA 1GZYB 1IGLA 5L3NA 1H59A 2DSRI 1TGRA 3LRIA 3KR3D 1BQTA 6INSE 1PMXA 1H02B 1EFEA 1GZRB 3GF1A 2DSQC 2DSPI 5L3LA 1B9GA 1GZZB 4XSSB 1ZEIA 2GF1A 2KJIA
chains in the Genus database with same CATH superfamily
2L14B 2L29B 5L3MA 2LWZA 1IMXA 2KQPA 2JZQA 1WQJI 1SJUA 1GZYB 1IGLA 5L3NA 1H59A 2DSRI 1TGRA 3LRIA 3KR3D 1BQTA 6INSE 1PMXA 1H02B 1EFEA 1GZRB 3GF1A 2DSQC 2DSPI 3F2BA 5L3LA 1B9GA 3F2DA 1GZZB 4XSSB 1ZEIA 3F2CA 2GF1A 2KJIA
chains in the Genus database with same CATH topology
2L29B 5L3MA 2LWZA 1IMXA 2KQPA 2JZQA 1WQJI 1SJUA 1GZYB 1IGLA 5L3NA 1H59A 2DSRI 1TGRA 3LRIA 3KR3D 1BQTA 6INSE 1PMXA 1H02B 1EFEA 1GZRB 3GF1A 2DSQC 2DSPI 5L3LA 1B9GA 1GZZB 4XSSB 1ZEIA 2GF1A 2KJIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2L29 B;  5L3M A;  2LWZ A;  1IMX A;  2KQP A;  2JZQ A;  1WQJ I;  1SJU A;  1GZY B;  1IGL A;  5L3N A;  1H59 A;  2DSR I;  1TGR A;  3LRI A;  3KR3 D;  1BQT A;  6INS E;  1PMX A;  1H02 B;  1EFE A;  1GZR B;  3GF1 A;  2DSQ C;  2DSP I;  5L3L A;  1B9G A;  1GZZ B;  4XSS B;  1ZEI A;  2GF1 A;  2KJI A; 
#chains in the Genus database with same CATH topology
 2L14 B;  2L29 B;  5L3M A;  2LWZ A;  1IMX A;  2KQP A;  2JZQ A;  1WQJ I;  1SJU A;  1GZY B;  1IGL A;  5L3N A;  1H59 A;  2DSR I;  1TGR A;  3LRI A;  3KR3 D;  1BQT A;  6INS E;  1PMX A;  1H02 B;  1EFE A;  1GZR B;  3GF1 A;  2DSQ C;  2DSP I;  3F2B A;  5L3L A;  1B9G A;  3F2D A;  1GZZ B;  4XSS B;  1ZEI A;  3F2C A;  2GF1 A;  2KJI A; 
#chains in the Genus database with same CATH homology
 2L29 B;  5L3M A;  2LWZ A;  1IMX A;  2KQP A;  2JZQ A;  1WQJ I;  1SJU A;  1GZY B;  1IGL A;  5L3N A;  1H59 A;  2DSR I;  1TGR A;  3LRI A;  3KR3 D;  1BQT A;  6INS E;  1PMX A;  1H02 B;  1EFE A;  1GZR B;  3GF1 A;  2DSQ C;  2DSP I;  5L3L A;  1B9G A;  1GZZ B;  4XSS B;  1ZEI A;  2GF1 A;  2KJI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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