1GZRB

Human insulin-like growth factor; esrf data
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
64
structure length
61
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSPQTGIVDECCFRSCDLRRLEMYCAPLKP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
molecule keywords INSULIN-LIKE GROWTH FACTOR I
molecule tags Growth factor
source organism Homo sapiens
total genus 14
structure length 61
sequence length 64
ec nomenclature
pdb deposition date 2002-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1gzrB00
1WQJI 3KR3D 2KJIA 1GZZB 2LWZA 2GF1A 3GF1A 1ZEIA 2DSQC 6INSE 2KQPA 1GZRB 1IMXA 1TGRA 1SJUA 5L3MA 5L3LA 2L29B 1H59A 2DSRI 1IGLA 1PMXA 4XSSB 1GZYB 3LRIA 2DSPI 5L3NA 1EFEA 2JZQA 1B9GA 1BQTA 1H02B
chains in the Genus database with same CATH superfamily
1WQJI 3KR3D 2KJIA 1GZZB 2LWZA 2GF1A 3GF1A 1ZEIA 2DSQC 6INSE 2KQPA 3F2CA 1GZRB 1IMXA 1TGRA 1SJUA 5L3MA 5L3LA 2L29B 1H59A 2DSRI 1IGLA 1PMXA 4XSSB 1GZYB 3LRIA 2DSPI 5L3NA 2L14B 1EFEA 2JZQA 3F2DA 1B9GA 1BQTA 3F2BA 1H02B
chains in the Genus database with same CATH topology
1WQJI 3KR3D 2KJIA 1GZZB 2LWZA 2GF1A 3GF1A 1ZEIA 2DSQC 6INSE 2KQPA 1GZRB 1IMXA 1TGRA 1SJUA 5L3MA 5L3LA 2L29B 1H59A 2DSRI 1IGLA 1PMXA 4XSSB 1GZYB 3LRIA 2DSPI 5L3NA 1EFEA 2JZQA 1B9GA 1BQTA 1H02B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQJ I;  3KR3 D;  2KJI A;  1GZZ B;  2LWZ A;  2GF1 A;  3GF1 A;  1ZEI A;  2DSQ C;  6INS E;  2KQP A;  1GZR B;  1IMX A;  1TGR A;  1SJU A;  5L3M A;  5L3L A;  2L29 B;  1H59 A;  2DSR I;  1IGL A;  1PMX A;  4XSS B;  1GZY B;  3LRI A;  2DSP I;  5L3N A;  1EFE A;  2JZQ A;  1B9G A;  1BQT A;  1H02 B; 
#chains in the Genus database with same CATH topology
 1WQJ I;  3KR3 D;  2KJI A;  1GZZ B;  2LWZ A;  2GF1 A;  3GF1 A;  1ZEI A;  2DSQ C;  6INS E;  2KQP A;  3F2C A;  1GZR B;  1IMX A;  1TGR A;  1SJU A;  5L3M A;  5L3L A;  2L29 B;  1H59 A;  2DSR I;  1IGL A;  1PMX A;  4XSS B;  1GZY B;  3LRI A;  2DSP I;  5L3N A;  2L14 B;  1EFE A;  2JZQ A;  3F2D A;  1B9G A;  1BQT A;  3F2B A;  1H02 B; 
#chains in the Genus database with same CATH homology
 1WQJ I;  3KR3 D;  2KJI A;  1GZZ B;  2LWZ A;  2GF1 A;  3GF1 A;  1ZEI A;  2DSQ C;  6INS E;  2KQP A;  1GZR B;  1IMX A;  1TGR A;  1SJU A;  5L3M A;  5L3L A;  2L29 B;  1H59 A;  2DSR I;  1IGL A;  1PMX A;  4XSS B;  1GZY B;  3LRI A;  2DSP I;  5L3N A;  1EFE A;  2JZQ A;  1B9G A;  1BQT A;  1H02 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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