1H02B

Human insulin-like growth factor; srs daresbury data
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
66
structure length
64
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSAPQTGIVDECCFRSCDLRRLEMYCAPLKPAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords INSULIN-LIKE GROWTH FACTOR I
total genus 12
structure length 64
sequence length 66
ec nomenclature
pdb deposition date 2002-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1h02B00
1B9GA 2JZQA 5L3MA 3KR3D 1PMXA 5L3NA 1GZYB 1BQTA 1ZEIA 1TGRA 1IGLA 1EFEA 1H02B 2KJIA 3LRIA 1SJUA 1WQJI 3GF1A 1GZZB 2DSPI 2GF1A 2KQPA 1IMXA 2DSQC 4XSSB 2L29B 2DSRI 1GZRB 6INSE 2LWZA 1H59A 5L3LA
chains in the Genus database with same CATH superfamily
3F2BA 1B9GA 2JZQA 5L3MA 3KR3D 1PMXA 5L3NA 1GZYB 1BQTA 1ZEIA 1TGRA 1IGLA 1EFEA 1H02B 2KJIA 3LRIA 1SJUA 2L14B 1WQJI 3GF1A 1GZZB 2DSPI 2GF1A 2KQPA 1IMXA 3F2CA 2DSQC 4XSSB 2L29B 3F2DA 2DSRI 1GZRB 6INSE 2LWZA 1H59A 5L3LA
chains in the Genus database with same CATH topology
1B9GA 2JZQA 5L3MA 3KR3D 1PMXA 5L3NA 1GZYB 1BQTA 1ZEIA 1TGRA 1IGLA 1EFEA 1H02B 2KJIA 3LRIA 1SJUA 1WQJI 3GF1A 1GZZB 2DSPI 2GF1A 2KQPA 1IMXA 2DSQC 4XSSB 2L29B 2DSRI 1GZRB 6INSE 2LWZA 1H59A 5L3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B9G A;  2JZQ A;  5L3M A;  3KR3 D;  1PMX A;  5L3N A;  1GZY B;  1BQT A;  1ZEI A;  1TGR A;  1IGL A;  1EFE A;  1H02 B;  2KJI A;  3LRI A;  1SJU A;  1WQJ I;  3GF1 A;  1GZZ B;  2DSP I;  2GF1 A;  2KQP A;  1IMX A;  2DSQ C;  4XSS B;  2L29 B;  2DSR I;  1GZR B;  6INS E;  2LWZ A;  1H59 A;  5L3L A; 
#chains in the Genus database with same CATH topology
 3F2B A;  1B9G A;  2JZQ A;  5L3M A;  3KR3 D;  1PMX A;  5L3N A;  1GZY B;  1BQT A;  1ZEI A;  1TGR A;  1IGL A;  1EFE A;  1H02 B;  2KJI A;  3LRI A;  1SJU A;  2L14 B;  1WQJ I;  3GF1 A;  1GZZ B;  2DSP I;  2GF1 A;  2KQP A;  1IMX A;  3F2C A;  2DSQ C;  4XSS B;  2L29 B;  3F2D A;  2DSR I;  1GZR B;  6INS E;  2LWZ A;  1H59 A;  5L3L A; 
#chains in the Genus database with same CATH homology
 1B9G A;  2JZQ A;  5L3M A;  3KR3 D;  1PMX A;  5L3N A;  1GZY B;  1BQT A;  1ZEI A;  1TGR A;  1IGL A;  1EFE A;  1H02 B;  2KJI A;  3LRI A;  1SJU A;  1WQJ I;  3GF1 A;  1GZZ B;  2DSP I;  2GF1 A;  2KQP A;  1IMX A;  2DSQ C;  4XSS B;  2L29 B;  2DSR I;  1GZR B;  6INS E;  2LWZ A;  1H59 A;  5L3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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