1H7KA

Formation of a tyrosyl radical intermediate in proteus mirabilis catalase by directed mutagenesis and consequences for nucleotide reactivity
Total Genus 142
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
142
sequence length
475
structure length
474
Chain Sequence
KKLTTAAGAPVVDNNNVITAGPRGPMLLQDVWFLEKLAHFDREVIPERRHAKGSGAFGTFTVTHDITKYTRAKIFSEVGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDLNHIVKRDPRTNMRNMAYKWDFFSHLPESLHQLTIDMSDRGLPLSYRFVHGFGSHTYSFINKDNERFWVKFHYRCQQGIKNLMDDEAEALVGKDRESSQRDLFEAIERGDYPRWKLQIQIMPEKEASTVPYNPFDLTKVWPHADYPLMDVGYFELNRNPDNYFSDVEQAAFSPANIVPGISFSPDKMLQGRLFSYGDAHRYRLGVNHHQIPVNAPKCPFHNYHRDGAMRVDGNSGNGITYEPNSGGVFQEQPDFKEPPLSIEGAADHWNHREDEDYFSQPRALYELLSDDEHQRMFARIAGELSQASKETQQRQIDLFTKVHPEYGAGVEKAIKVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Formation of a Tyrosyl Radical Intermediate in Proteus Mirabilis Catalase by Directed Mutagenesis and Consequences for Nucleotide Reactivity.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Proteus mirabilis
molecule keywords CATALASE
total genus 142
structure length 474
sequence length 475
ec nomenclature ec 1.11.1.6: Catalase.
pdb deposition date 2001-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00199 Catalase Catalase
A PF06628 Catalase-rel Catalase-related immune-responsive
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.180.10 Mainly Beta Beta Barrel Catalase HpII, Chain A, domain 1 Catalase core domain 1h7kA00
1U5UA 1GGJA 3PQ7A 3PQ5A 3TTWA 1IPHA 1GWHA 2IUFA 4B5KA 3PQ2A 4QOQA 1F4JA 3TTXA 3PQ6A 1P7ZA 1P7YA 4ENWA 4QONA 3P9SA 5BV2P 4ENRA 4ENTA 1HBZA 4ENSA 2CAHA 1CF9A 4QOMA 4AJ9A 1QWLA 1MQFA 2A9EA 4BIMA 2CAGA 4B31A 2J2MA 1GGFA 1GGEA 1H7KA 1SY7A 4CABA 1GGKA 1M85A 1SI8A 4ENQA 3ZJ4A 4AUNA 4AULA 1P81A 3P9RA 1QF7A 1GGHA 4QOLA 4B7AA 1A4EA 4QORA 2IQFA 3DY5A 4ENUA 3ZJ5A 4B40A 1P80A 1QWSA 3P9PA 1GWFA 4BFLA 1E93A 4QOOA 3PQ3A 2XF2A 4B2YA 3EJ6A 1NM0A 1GWEA 3TTVA 3TTTA 1QWMA 4QOPA 1GG9A 3TTUA 4AUMA 4AUEA 4ENPA 3PQ8A 4ENVA 3P9QA 2ISAA 4E37A 3VU3A 1M7SA 1H6NA 2XQ1A 3HB6A 3PQ4A
chains in the Genus database with same CATH superfamily
1U5UA 1GGJA 3PQ7A 3PQ5A 3TTWA 1IPHA 1GWHA 2IUFA 3RGPA 4B7GA 4B5KA 3PQ2A 4QOQA 1QQWA 1F4JA 3TTXA 3PQ6A 1P7ZA 1P7YA 4ENWA 4QONA 1DGHB 3P9SA 5BV2P 4ENRA 4ENTA 1HBZA 1TGUA 4ENSA 2CAHA 1CF9A 4QOMA 1DGHA 4AJ9A 1QWLA 1MQFA 2A9EA 4BIMA 2CAGA 4B31A 2J2MA 1GGFA 1GGEA 1H7KA 1SY7A 4CABA 1GGKA 1M85A 1DGFA 1SI8A 4ENQA 3ZJ4A 4AUNA 4AULA 1P81A 3P9RA 3RGSA 1QF7A 3J7BA 1GGHA 4B7FA 4QOLA 4B7AA 1A4EA 4QORA 2IQFA 3DY5A 4ENUA 3ZJ5A 4B40A 1P80A 1QWSA 3E4WA 3P9PA 1TH2A 1GWFA 4BFLA 1TH3A 1DGGA 1E93A 4QOOA 3PQ3A 2XF2A 4B7HA 4B2YA 3EJ6A 1NM0A 1DGBA 1GWEA 3TTVA 3TTTA 1QWMA 8CATA 4QOPA 1GG9A 3TTUA 4AUMA 5GKNA 3RE8A 4AUEA 4ENPA 1TH4A 3PQ8A 4ENVA 3E4YA 3P9QA 4BLCA 2ISAA 3NWLA 4E37A 3VU3A 1M7SA 7CATA 1H6NA 2XQ1A 3HB6A 3PQ4A
chains in the Genus database with same CATH topology
1U5UA 1GGJA 3PQ7A 3PQ5A 3TTWA 1IPHA 1GWHA 2IUFA 4B5KA 3PQ2A 4QOQA 1F4JA 3TTXA 3PQ6A 1P7ZA 1P7YA 4ENWA 4QONA 3P9SA 5BV2P 4ENRA 4ENTA 1HBZA 4ENSA 2CAHA 1CF9A 4QOMA 4AJ9A 1QWLA 1MQFA 2A9EA 4BIMA 2CAGA 4B31A 2J2MA 1GGFA 1GGEA 1H7KA 1SY7A 4CABA 1GGKA 1M85A 1SI8A 4ENQA 3ZJ4A 4AUNA 4AULA 1P81A 3P9RA 1QF7A 1GGHA 4QOLA 4B7AA 1A4EA 4QORA 2IQFA 3DY5A 4ENUA 3ZJ5A 4B40A 1P80A 1QWSA 3P9PA 1GWFA 4BFLA 1E93A 4QOOA 3PQ3A 2XF2A 4B2YA 3EJ6A 1NM0A 1GWEA 3TTVA 3TTTA 1QWMA 4QOPA 1GG9A 3TTUA 4AUMA 4AUEA 4ENPA 3PQ8A 4ENVA 3P9QA 2ISAA 4E37A 3VU3A 1M7SA 1H6NA 2XQ1A 3HB6A 3PQ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1U5U A;  1GGJ A;  3PQ7 A;  3PQ5 A;  3TTW A;  1IPH A;  1GWH A;  2IUF A;  4B5K A;  3PQ2 A;  4QOQ A;  1F4J A;  3TTX A;  3PQ6 A;  1P7Z A;  1P7Y A;  4ENW A;  4QON A;  3P9S A;  5BV2 P;  4ENR A;  4ENT A;  1HBZ A;  4ENS A;  2CAH A;  1CF9 A;  4QOM A;  4AJ9 A;  1QWL A;  1MQF A;  2A9E A;  4BIM A;  2CAG A;  4B31 A;  2J2M A;  1GGF A;  1GGE A;  1H7K A;  1SY7 A;  4CAB A;  1GGK A;  1M85 A;  1SI8 A;  4ENQ A;  3ZJ4 A;  4AUN A;  4AUL A;  1P81 A;  3P9R A;  1QF7 A;  1GGH A;  4QOL A;  4B7A A;  1A4E A;  4QOR A;  2IQF A;  3DY5 A;  4ENU A;  3ZJ5 A;  4B40 A;  1P80 A;  1QWS A;  3P9P A;  1GWF A;  4BFL A;  1E93 A;  4QOO A;  3PQ3 A;  2XF2 A;  4B2Y A;  3EJ6 A;  1NM0 A;  1GWE A;  3TTV A;  3TTT A;  1QWM A;  4QOP A;  1GG9 A;  3TTU A;  4AUM A;  4AUE A;  4ENP A;  3PQ8 A;  4ENV A;  3P9Q A;  2ISA A;  4E37 A;  3VU3 A;  1M7S A;  1H6N A;  2XQ1 A;  3HB6 A;  3PQ4 A; 
#chains in the Genus database with same CATH topology
 1U5U A;  1GGJ A;  3PQ7 A;  3PQ5 A;  3TTW A;  1IPH A;  1GWH A;  2IUF A;  3RGP A;  4B7G A;  4B5K A;  3PQ2 A;  4QOQ A;  1QQW A;  1F4J A;  3TTX A;  3PQ6 A;  1P7Z A;  1P7Y A;  4ENW A;  4QON A;  1DGH B;  3P9S A;  5BV2 P;  4ENR A;  4ENT A;  1HBZ A;  1TGU A;  4ENS A;  2CAH A;  1CF9 A;  4QOM A;  1DGH A;  4AJ9 A;  1QWL A;  1MQF A;  2A9E A;  4BIM A;  2CAG A;  4B31 A;  2J2M A;  1GGF A;  1GGE A;  1H7K A;  1SY7 A;  4CAB A;  1GGK A;  1M85 A;  1DGF A;  1SI8 A;  4ENQ A;  3ZJ4 A;  4AUN A;  4AUL A;  1P81 A;  3P9R A;  3RGS A;  1QF7 A;  3J7B A;  1GGH A;  4B7F A;  4QOL A;  4B7A A;  1A4E A;  4QOR A;  2IQF A;  3DY5 A;  4ENU A;  3ZJ5 A;  4B40 A;  1P80 A;  1QWS A;  3E4W A;  3P9P A;  1TH2 A;  1GWF A;  4BFL A;  1TH3 A;  1DGG A;  1E93 A;  4QOO A;  3PQ3 A;  2XF2 A;  4B7H A;  4B2Y A;  3EJ6 A;  1NM0 A;  1DGB A;  1GWE A;  3TTV A;  3TTT A;  1QWM A;  8CAT A;  4QOP A;  1GG9 A;  3TTU A;  4AUM A;  5GKN A;  3RE8 A;  4AUE A;  4ENP A;  1TH4 A;  3PQ8 A;  4ENV A;  3E4Y A;  3P9Q A;  4BLC A;  2ISA A;  3NWL A;  4E37 A;  3VU3 A;  1M7S A;  7CAT A;  1H6N A;  2XQ1 A;  3HB6 A;  3PQ4 A; 
#chains in the Genus database with same CATH homology
 1U5U A;  1GGJ A;  3PQ7 A;  3PQ5 A;  3TTW A;  1IPH A;  1GWH A;  2IUF A;  4B5K A;  3PQ2 A;  4QOQ A;  1F4J A;  3TTX A;  3PQ6 A;  1P7Z A;  1P7Y A;  4ENW A;  4QON A;  3P9S A;  5BV2 P;  4ENR A;  4ENT A;  1HBZ A;  4ENS A;  2CAH A;  1CF9 A;  4QOM A;  4AJ9 A;  1QWL A;  1MQF A;  2A9E A;  4BIM A;  2CAG A;  4B31 A;  2J2M A;  1GGF A;  1GGE A;  1H7K A;  1SY7 A;  4CAB A;  1GGK A;  1M85 A;  1SI8 A;  4ENQ A;  3ZJ4 A;  4AUN A;  4AUL A;  1P81 A;  3P9R A;  1QF7 A;  1GGH A;  4QOL A;  4B7A A;  1A4E A;  4QOR A;  2IQF A;  3DY5 A;  4ENU A;  3ZJ5 A;  4B40 A;  1P80 A;  1QWS A;  3P9P A;  1GWF A;  4BFL A;  1E93 A;  4QOO A;  3PQ3 A;  2XF2 A;  4B2Y A;  3EJ6 A;  1NM0 A;  1GWE A;  3TTV A;  3TTT A;  1QWM A;  4QOP A;  1GG9 A;  3TTU A;  4AUM A;  4AUE A;  4ENP A;  3PQ8 A;  4ENV A;  3P9Q A;  2ISA A;  4E37 A;  3VU3 A;  1M7S A;  1H6N A;  2XQ1 A;  3HB6 A;  3PQ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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