1IGLA

Solution structure of human insulin-like growth factor ii relationship to receptor and binding protein interactions
Total Genus 11
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
11
sequence length
67
structure length
67
Chain Sequence
AYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions.
pubmed rcsb
molecule keywords INSULIN-LIKE GROWTH FACTOR II
molecule tags Growth factor
source organism Homo sapiens
total genus 11
structure length 67
sequence length 67
ec nomenclature
pdb deposition date 1994-12-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1iglA00
5L3LA 5L3NA 3KR3D 1GZZB 1TGRA 5L3MA 1SJUA 2DSQC 1H02B 1GZYB 2GF1A 1IGLA 3LRIA 1ZEIA 3GF1A 1WQJI 2DSPI 2LWZA 1PMXA 1B9GA 1H59A 2JZQA 2L29B 2DSRI 1BQTA 2KQPA 1GZRB 1EFEA 1IMXA 2KJIA 6INSE 4XSSB
chains in the Genus database with same CATH superfamily
5L3LA 5L3NA 3KR3D 1GZZB 1TGRA 5L3MA 1SJUA 2DSQC 1H02B 1GZYB 2GF1A 1IGLA 3F2BA 3LRIA 1ZEIA 3GF1A 1WQJI 2DSPI 2LWZA 1PMXA 1B9GA 1H59A 2JZQA 2L29B 2DSRI 3F2DA 1BQTA 2L14B 2KQPA 1GZRB 1EFEA 1IMXA 3F2CA 2KJIA 6INSE 4XSSB
chains in the Genus database with same CATH topology
5L3LA 5L3NA 3KR3D 1GZZB 1TGRA 5L3MA 1SJUA 2DSQC 1H02B 1GZYB 2GF1A 1IGLA 3LRIA 1ZEIA 3GF1A 1WQJI 2DSPI 2LWZA 1PMXA 1B9GA 1H59A 2JZQA 2L29B 2DSRI 1BQTA 2KQPA 1GZRB 1EFEA 1IMXA 2KJIA 6INSE 4XSSB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L3L A;  5L3N A;  3KR3 D;  1GZZ B;  1TGR A;  5L3M A;  1SJU A;  2DSQ C;  1H02 B;  1GZY B;  2GF1 A;  1IGL A;  3LRI A;  1ZEI A;  3GF1 A;  1WQJ I;  2DSP I;  2LWZ A;  1PMX A;  1B9G A;  1H59 A;  2JZQ A;  2L29 B;  2DSR I;  1BQT A;  2KQP A;  1GZR B;  1EFE A;  1IMX A;  2KJI A;  6INS E;  4XSS B; 
#chains in the Genus database with same CATH topology
 5L3L A;  5L3N A;  3KR3 D;  1GZZ B;  1TGR A;  5L3M A;  1SJU A;  2DSQ C;  1H02 B;  1GZY B;  2GF1 A;  1IGL A;  3F2B A;  3LRI A;  1ZEI A;  3GF1 A;  1WQJ I;  2DSP I;  2LWZ A;  1PMX A;  1B9G A;  1H59 A;  2JZQ A;  2L29 B;  2DSR I;  3F2D A;  1BQT A;  2L14 B;  2KQP A;  1GZR B;  1EFE A;  1IMX A;  3F2C A;  2KJI A;  6INS E;  4XSS B; 
#chains in the Genus database with same CATH homology
 5L3L A;  5L3N A;  3KR3 D;  1GZZ B;  1TGR A;  5L3M A;  1SJU A;  2DSQ C;  1H02 B;  1GZY B;  2GF1 A;  1IGL A;  3LRI A;  1ZEI A;  3GF1 A;  1WQJ I;  2DSP I;  2LWZ A;  1PMX A;  1B9G A;  1H59 A;  2JZQ A;  2L29 B;  2DSR I;  1BQT A;  2KQP A;  1GZR B;  1EFE A;  1IMX A;  2KJI A;  6INS E;  4XSS B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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