1IMXA

1.8 angstrom crystal structure of igf-1
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
62
structure length
56
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSTGIVDECCFRSCDLRRLEMYCAPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Insulin-like Growth Factor 1A
total genus 16
structure length 56
sequence length 62
ec nomenclature
pdb deposition date 2001-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1imxA00
1H59A 2KQPA 1ZEIA 4XSSB 3KR3D 2DSRI 2DSQC 5L3LA 1EFEA 2KJIA 1B9GA 2DSPI 6INSE 5L3MA 1SJUA 1TGRA 1PMXA 2L29B 2LWZA 3GF1A 1BQTA 2GF1A 1GZZB 1IMXA 1GZYB 3LRIA 1GZRB 1IGLA 1H02B 1WQJI 5L3NA 2JZQA
chains in the Genus database with same CATH superfamily
1H59A 3F2DA 2KQPA 1ZEIA 4XSSB 3KR3D 2L14B 2DSRI 2DSQC 5L3LA 1EFEA 2KJIA 3F2BA 1B9GA 2DSPI 6INSE 5L3MA 1SJUA 1TGRA 1PMXA 2L29B 2LWZA 3GF1A 1BQTA 2GF1A 1GZZB 1IMXA 3F2CA 1GZYB 3LRIA 1GZRB 1IGLA 1H02B 1WQJI 5L3NA 2JZQA
chains in the Genus database with same CATH topology
1H59A 2KQPA 1ZEIA 4XSSB 3KR3D 2DSRI 2DSQC 5L3LA 1EFEA 2KJIA 1B9GA 2DSPI 6INSE 5L3MA 1SJUA 1TGRA 1PMXA 2L29B 2LWZA 3GF1A 1BQTA 2GF1A 1GZZB 1IMXA 1GZYB 3LRIA 1GZRB 1IGLA 1H02B 1WQJI 5L3NA 2JZQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H59 A;  2KQP A;  1ZEI A;  4XSS B;  3KR3 D;  2DSR I;  2DSQ C;  5L3L A;  1EFE A;  2KJI A;  1B9G A;  2DSP I;  6INS E;  5L3M A;  1SJU A;  1TGR A;  1PMX A;  2L29 B;  2LWZ A;  3GF1 A;  1BQT A;  2GF1 A;  1GZZ B;  1IMX A;  1GZY B;  3LRI A;  1GZR B;  1IGL A;  1H02 B;  1WQJ I;  5L3N A;  2JZQ A; 
#chains in the Genus database with same CATH topology
 1H59 A;  3F2D A;  2KQP A;  1ZEI A;  4XSS B;  3KR3 D;  2L14 B;  2DSR I;  2DSQ C;  5L3L A;  1EFE A;  2KJI A;  3F2B A;  1B9G A;  2DSP I;  6INS E;  5L3M A;  1SJU A;  1TGR A;  1PMX A;  2L29 B;  2LWZ A;  3GF1 A;  1BQT A;  2GF1 A;  1GZZ B;  1IMX A;  3F2C A;  1GZY B;  3LRI A;  1GZR B;  1IGL A;  1H02 B;  1WQJ I;  5L3N A;  2JZQ A; 
#chains in the Genus database with same CATH homology
 1H59 A;  2KQP A;  1ZEI A;  4XSS B;  3KR3 D;  2DSR I;  2DSQ C;  5L3L A;  1EFE A;  2KJI A;  1B9G A;  2DSP I;  6INS E;  5L3M A;  1SJU A;  1TGR A;  1PMX A;  2L29 B;  2LWZ A;  3GF1 A;  1BQT A;  2GF1 A;  1GZZ B;  1IMX A;  1GZY B;  3LRI A;  1GZR B;  1IGL A;  1H02 B;  1WQJ I;  5L3N A;  2JZQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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