1IMXA

1.8 angstrom crystal structure of igf-1
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
62
structure length
56
Chain Sequence
ETLCGAELVDALQFVCGDRGFYFNKPTGYGSSTGIVDECCFRSCDLRRLEMYCAPL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
pubmed doi rcsb
molecule keywords Insulin-like Growth Factor 1A
molecule tags Hormone/growth factor
source organism Homo sapiens
total genus 16
structure length 56
sequence length 62
ec nomenclature
pdb deposition date 2001-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1imxA00
1B9GA 2JZQA 1TGRA 1SJUA 1ZEIA 2DSPI 1GZYB 1WQJI 1EFEA 1GZZB 3KR3D 3LRIA 1IGLA 2DSRI 6INSE 2KJIA 1H02B 2KQPA 1BQTA 1H59A 3GF1A 5L3NA 4XSSB 2LWZA 5L3LA 2L29B 1PMXA 2GF1A 1IMXA 5L3MA 2DSQC 1GZRB
chains in the Genus database with same CATH superfamily
1B9GA 2JZQA 1TGRA 3F2BA 1SJUA 1ZEIA 2DSPI 1GZYB 1WQJI 1EFEA 1GZZB 3KR3D 3LRIA 3F2CA 1IGLA 2DSRI 6INSE 2KJIA 1H02B 2KQPA 2L14B 1BQTA 1H59A 3F2DA 3GF1A 5L3NA 4XSSB 2LWZA 5L3LA 2L29B 1PMXA 2GF1A 1IMXA 5L3MA 2DSQC 1GZRB
chains in the Genus database with same CATH topology
1B9GA 2JZQA 1TGRA 1SJUA 1ZEIA 2DSPI 1GZYB 1WQJI 1EFEA 1GZZB 3KR3D 3LRIA 1IGLA 2DSRI 6INSE 2KJIA 1H02B 2KQPA 1BQTA 1H59A 3GF1A 5L3NA 4XSSB 2LWZA 5L3LA 2L29B 1PMXA 2GF1A 1IMXA 5L3MA 2DSQC 1GZRB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B9G A;  2JZQ A;  1TGR A;  1SJU A;  1ZEI A;  2DSP I;  1GZY B;  1WQJ I;  1EFE A;  1GZZ B;  3KR3 D;  3LRI A;  1IGL A;  2DSR I;  6INS E;  2KJI A;  1H02 B;  2KQP A;  1BQT A;  1H59 A;  3GF1 A;  5L3N A;  4XSS B;  2LWZ A;  5L3L A;  2L29 B;  1PMX A;  2GF1 A;  1IMX A;  5L3M A;  2DSQ C;  1GZR B; 
#chains in the Genus database with same CATH topology
 1B9G A;  2JZQ A;  1TGR A;  3F2B A;  1SJU A;  1ZEI A;  2DSP I;  1GZY B;  1WQJ I;  1EFE A;  1GZZ B;  3KR3 D;  3LRI A;  3F2C A;  1IGL A;  2DSR I;  6INS E;  2KJI A;  1H02 B;  2KQP A;  2L14 B;  1BQT A;  1H59 A;  3F2D A;  3GF1 A;  5L3N A;  4XSS B;  2LWZ A;  5L3L A;  2L29 B;  1PMX A;  2GF1 A;  1IMX A;  5L3M A;  2DSQ C;  1GZR B; 
#chains in the Genus database with same CATH homology
 1B9G A;  2JZQ A;  1TGR A;  1SJU A;  1ZEI A;  2DSP I;  1GZY B;  1WQJ I;  1EFE A;  1GZZ B;  3KR3 D;  3LRI A;  1IGL A;  2DSR I;  6INS E;  2KJI A;  1H02 B;  2KQP A;  1BQT A;  1H59 A;  3GF1 A;  5L3N A;  4XSS B;  2LWZ A;  5L3L A;  2L29 B;  1PMX A;  2GF1 A;  1IMX A;  5L3M A;  2DSQ C;  1GZR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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