1PMXA

Insulin-like growth factor-i bound to a phage-derived peptide
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
70
structure length
70
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complex with a Phage Display-Derived Peptide Provides Insight into the Function of Insulin-like Growth Factor I
pubmed doi rcsb
molecule keywords Insulin-like growth factor IB
molecule tags Hormone/growth factor
source organism Homo sapiens
total genus 10
structure length 70
sequence length 70
ec nomenclature
pdb deposition date 2003-06-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1pmxA00
5L3NA 2L29B 1EFEA 1TGRA 1H02B 5L3LA 2LWZA 4XSSB 2JZQA 3LRIA 2KJIA 3GF1A 2DSRI 1GZYB 2DSQC 1WQJI 1B9GA 2GF1A 3KR3D 2KQPA 5L3MA 1IMXA 1H59A 1GZRB 1PMXA 6INSE 2DSPI 1ZEIA 1SJUA 1IGLA 1BQTA 1GZZB
chains in the Genus database with same CATH superfamily
5L3NA 2L29B 1EFEA 1TGRA 1H02B 5L3LA 2LWZA 2L14B 4XSSB 2JZQA 3LRIA 2KJIA 3GF1A 2DSRI 1GZYB 2DSQC 3F2BA 1WQJI 1B9GA 2GF1A 3KR3D 2KQPA 5L3MA 1IMXA 1H59A 1GZRB 1PMXA 3F2DA 3F2CA 6INSE 2DSPI 1ZEIA 1SJUA 1IGLA 1BQTA 1GZZB
chains in the Genus database with same CATH topology
5L3NA 2L29B 1EFEA 1TGRA 1H02B 5L3LA 2LWZA 4XSSB 2JZQA 3LRIA 2KJIA 3GF1A 2DSRI 1GZYB 2DSQC 1WQJI 1B9GA 2GF1A 3KR3D 2KQPA 5L3MA 1IMXA 1H59A 1GZRB 1PMXA 6INSE 2DSPI 1ZEIA 1SJUA 1IGLA 1BQTA 1GZZB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5L3N A;  2L29 B;  1EFE A;  1TGR A;  1H02 B;  5L3L A;  2LWZ A;  4XSS B;  2JZQ A;  3LRI A;  2KJI A;  3GF1 A;  2DSR I;  1GZY B;  2DSQ C;  1WQJ I;  1B9G A;  2GF1 A;  3KR3 D;  2KQP A;  5L3M A;  1IMX A;  1H59 A;  1GZR B;  1PMX A;  6INS E;  2DSP I;  1ZEI A;  1SJU A;  1IGL A;  1BQT A;  1GZZ B; 
#chains in the Genus database with same CATH topology
 5L3N A;  2L29 B;  1EFE A;  1TGR A;  1H02 B;  5L3L A;  2LWZ A;  2L14 B;  4XSS B;  2JZQ A;  3LRI A;  2KJI A;  3GF1 A;  2DSR I;  1GZY B;  2DSQ C;  3F2B A;  1WQJ I;  1B9G A;  2GF1 A;  3KR3 D;  2KQP A;  5L3M A;  1IMX A;  1H59 A;  1GZR B;  1PMX A;  3F2D A;  3F2C A;  6INS E;  2DSP I;  1ZEI A;  1SJU A;  1IGL A;  1BQT A;  1GZZ B; 
#chains in the Genus database with same CATH homology
 5L3N A;  2L29 B;  1EFE A;  1TGR A;  1H02 B;  5L3L A;  2LWZ A;  4XSS B;  2JZQ A;  3LRI A;  2KJI A;  3GF1 A;  2DSR I;  1GZY B;  2DSQ C;  1WQJ I;  1B9G A;  2GF1 A;  3KR3 D;  2KQP A;  5L3M A;  1IMX A;  1H59 A;  1GZR B;  1PMX A;  6INS E;  2DSP I;  1ZEI A;  1SJU A;  1IGL A;  1BQT A;  1GZZ B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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