1TGRA

Crystal structure of mini-igf-1(2)
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
52
structure length
52
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPKAKGIVDECCFRSCDLRRLEMYCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Insulin-like growth factor IA
total genus 16
structure length 52
sequence length 52
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1tgrA00
1B9GA 1IGLA 1PMXA 1SJUA 6INSE 3GF1A 2DSRI 2JZQA 1GZZB 2LWZA 2DSPI 1GZRB 1H02B 4XSSB 5L3MA 1WQJI 2GF1A 2L29B 1ZEIA 1EFEA 1H59A 2KQPA 1BQTA 2KJIA 1TGRA 3KR3D 5L3LA 1IMXA 1GZYB 3LRIA 5L3NA 2DSQC
chains in the Genus database with same CATH superfamily
1B9GA 1IGLA 1PMXA 1SJUA 6INSE 3GF1A 2DSRI 2JZQA 1GZZB 2LWZA 2DSPI 1GZRB 1H02B 4XSSB 5L3MA 1WQJI 2GF1A 3F2BA 2L29B 1ZEIA 1EFEA 2L14B 1H59A 2KQPA 1BQTA 2KJIA 1TGRA 3F2CA 3KR3D 5L3LA 1IMXA 1GZYB 3LRIA 3F2DA 5L3NA 2DSQC
chains in the Genus database with same CATH topology
1B9GA 1IGLA 1PMXA 1SJUA 6INSE 3GF1A 2DSRI 2JZQA 1GZZB 2LWZA 2DSPI 1GZRB 1H02B 4XSSB 5L3MA 1WQJI 2GF1A 2L29B 1ZEIA 1EFEA 1H59A 2KQPA 1BQTA 2KJIA 1TGRA 3KR3D 5L3LA 1IMXA 1GZYB 3LRIA 5L3NA 2DSQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1B9G A;  1IGL A;  1PMX A;  1SJU A;  6INS E;  3GF1 A;  2DSR I;  2JZQ A;  1GZZ B;  2LWZ A;  2DSP I;  1GZR B;  1H02 B;  4XSS B;  5L3M A;  1WQJ I;  2GF1 A;  2L29 B;  1ZEI A;  1EFE A;  1H59 A;  2KQP A;  1BQT A;  2KJI A;  1TGR A;  3KR3 D;  5L3L A;  1IMX A;  1GZY B;  3LRI A;  5L3N A;  2DSQ C; 
#chains in the Genus database with same CATH topology
 1B9G A;  1IGL A;  1PMX A;  1SJU A;  6INS E;  3GF1 A;  2DSR I;  2JZQ A;  1GZZ B;  2LWZ A;  2DSP I;  1GZR B;  1H02 B;  4XSS B;  5L3M A;  1WQJ I;  2GF1 A;  3F2B A;  2L29 B;  1ZEI A;  1EFE A;  2L14 B;  1H59 A;  2KQP A;  1BQT A;  2KJI A;  1TGR A;  3F2C A;  3KR3 D;  5L3L A;  1IMX A;  1GZY B;  3LRI A;  3F2D A;  5L3N A;  2DSQ C; 
#chains in the Genus database with same CATH homology
 1B9G A;  1IGL A;  1PMX A;  1SJU A;  6INS E;  3GF1 A;  2DSR I;  2JZQ A;  1GZZ B;  2LWZ A;  2DSP I;  1GZR B;  1H02 B;  4XSS B;  5L3M A;  1WQJ I;  2GF1 A;  2L29 B;  1ZEI A;  1EFE A;  1H59 A;  2KQP A;  1BQT A;  2KJI A;  1TGR A;  3KR3 D;  5L3L A;  1IMX A;  1GZY B;  3LRI A;  5L3N A;  2DSQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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