1TGRA

Crystal structure of mini-igf-1(2)
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
52
structure length
52
Chain Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPKAKGIVDECCFRSCDLRRLEMYCA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 1.42A crystal structure of mini-IGF-1(2): an analysis of the disulfide isomerization property and receptor binding property of IGF-1 based on the three-dimensional structure
pubmed doi rcsb
molecule tags Hormone/growth factor
source organism Homo sapiens
molecule keywords Insulin-like growth factor IA
total genus 16
structure length 52
sequence length 52
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1tgrA00
2KJIA 2DSRI 1B9GA 2L29B 1GZRB 2GF1A 5L3NA 1TGRA 1GZZB 4XSSB 2DSPI 1PMXA 1EFEA 3LRIA 1SJUA 1H02B 2KQPA 1IGLA 1WQJI 2JZQA 1GZYB 1H59A 3GF1A 2LWZA 5L3MA 1BQTA 2DSQC 1IMXA 3KR3D 6INSE 1ZEIA 5L3LA
chains in the Genus database with same CATH superfamily
2KJIA 2DSRI 1B9GA 2L29B 2L14B 1GZRB 2GF1A 5L3NA 1TGRA 1GZZB 4XSSB 2DSPI 1PMXA 3F2DA 1EFEA 3LRIA 1SJUA 3F2BA 1H02B 2KQPA 1IGLA 1WQJI 2JZQA 1GZYB 1H59A 3GF1A 2LWZA 5L3MA 1BQTA 2DSQC 3F2CA 1IMXA 3KR3D 6INSE 1ZEIA 5L3LA
chains in the Genus database with same CATH topology
2KJIA 2DSRI 1B9GA 2L29B 1GZRB 2GF1A 5L3NA 1TGRA 1GZZB 4XSSB 2DSPI 1PMXA 1EFEA 3LRIA 1SJUA 1H02B 2KQPA 1IGLA 1WQJI 2JZQA 1GZYB 1H59A 3GF1A 2LWZA 5L3MA 1BQTA 2DSQC 1IMXA 3KR3D 6INSE 1ZEIA 5L3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KJI A;  2DSR I;  1B9G A;  2L29 B;  1GZR B;  2GF1 A;  5L3N A;  1TGR A;  1GZZ B;  4XSS B;  2DSP I;  1PMX A;  1EFE A;  3LRI A;  1SJU A;  1H02 B;  2KQP A;  1IGL A;  1WQJ I;  2JZQ A;  1GZY B;  1H59 A;  3GF1 A;  2LWZ A;  5L3M A;  1BQT A;  2DSQ C;  1IMX A;  3KR3 D;  6INS E;  1ZEI A;  5L3L A; 
#chains in the Genus database with same CATH topology
 2KJI A;  2DSR I;  1B9G A;  2L29 B;  2L14 B;  1GZR B;  2GF1 A;  5L3N A;  1TGR A;  1GZZ B;  4XSS B;  2DSP I;  1PMX A;  3F2D A;  1EFE A;  3LRI A;  1SJU A;  3F2B A;  1H02 B;  2KQP A;  1IGL A;  1WQJ I;  2JZQ A;  1GZY B;  1H59 A;  3GF1 A;  2LWZ A;  5L3M A;  1BQT A;  2DSQ C;  3F2C A;  1IMX A;  3KR3 D;  6INS E;  1ZEI A;  5L3L A; 
#chains in the Genus database with same CATH homology
 2KJI A;  2DSR I;  1B9G A;  2L29 B;  1GZR B;  2GF1 A;  5L3N A;  1TGR A;  1GZZ B;  4XSS B;  2DSP I;  1PMX A;  1EFE A;  3LRI A;  1SJU A;  1H02 B;  2KQP A;  1IGL A;  1WQJ I;  2JZQ A;  1GZY B;  1H59 A;  3GF1 A;  2LWZ A;  5L3M A;  1BQT A;  2DSQ C;  1IMX A;  3KR3 D;  6INS E;  1ZEI A;  5L3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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