1WQJI

Structural basis for the regulation of insulin-like growth factors (igfs) by igf binding proteins (igfbps)
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
62
structure length
62
Chain Sequence
PETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the regulation of insulin-like growth factors by IGF binding proteins
pubmed doi rcsb
molecule tags Protein binding/hormone/growth factor
source organism Homo sapiens
molecule keywords Insulin-like growth factor binding protein 4
total genus 15
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2004-09-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1wqjI00
1WQJI 1IGLA 2L29B 2DSRI 2GF1A 3LRIA 2KQPA 1IMXA 5L3LA 3GF1A 1EFEA 2KJIA 1GZRB 5L3MA 4XSSB 1SJUA 2DSQC 2DSPI 1H02B 1ZEIA 1PMXA 1BQTA 1GZZB 5L3NA 6INSE 1TGRA 3KR3D 1GZYB 2JZQA 2LWZA 1B9GA 1H59A
chains in the Genus database with same CATH superfamily
1WQJI 1IGLA 2L29B 2DSRI 2GF1A 2L14B 2KQPA 1IMXA 3LRIA 5L3LA 3F2DA 3GF1A 1EFEA 2KJIA 3F2BA 1GZRB 5L3MA 4XSSB 1SJUA 2DSQC 2DSPI 1H02B 1ZEIA 1PMXA 3F2CA 1BQTA 1GZZB 5L3NA 6INSE 1TGRA 3KR3D 1GZYB 2JZQA 2LWZA 1B9GA 1H59A
chains in the Genus database with same CATH topology
1WQJI 1IGLA 2L29B 2DSRI 2GF1A 3LRIA 2KQPA 1IMXA 5L3LA 3GF1A 1EFEA 2KJIA 1GZRB 5L3MA 4XSSB 1SJUA 2DSQC 2DSPI 1H02B 1ZEIA 1PMXA 1BQTA 1GZZB 5L3NA 6INSE 1TGRA 3KR3D 1GZYB 2JZQA 2LWZA 1B9GA 1H59A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WQJ I;  1IGL A;  2L29 B;  2DSR I;  2GF1 A;  3LRI A;  2KQP A;  1IMX A;  5L3L A;  3GF1 A;  1EFE A;  2KJI A;  1GZR B;  5L3M A;  4XSS B;  1SJU A;  2DSQ C;  2DSP I;  1H02 B;  1ZEI A;  1PMX A;  1BQT A;  1GZZ B;  5L3N A;  6INS E;  1TGR A;  3KR3 D;  1GZY B;  2JZQ A;  2LWZ A;  1B9G A;  1H59 A; 
#chains in the Genus database with same CATH topology
 1WQJ I;  1IGL A;  2L29 B;  2DSR I;  2GF1 A;  2L14 B;  2KQP A;  1IMX A;  3LRI A;  5L3L A;  3F2D A;  3GF1 A;  1EFE A;  2KJI A;  3F2B A;  1GZR B;  5L3M A;  4XSS B;  1SJU A;  2DSQ C;  2DSP I;  1H02 B;  1ZEI A;  1PMX A;  3F2C A;  1BQT A;  1GZZ B;  5L3N A;  6INS E;  1TGR A;  3KR3 D;  1GZY B;  2JZQ A;  2LWZ A;  1B9G A;  1H59 A; 
#chains in the Genus database with same CATH homology
 1WQJ I;  1IGL A;  2L29 B;  2DSR I;  2GF1 A;  3LRI A;  2KQP A;  1IMX A;  5L3L A;  3GF1 A;  1EFE A;  2KJI A;  1GZR B;  5L3M A;  4XSS B;  1SJU A;  2DSQ C;  2DSP I;  1H02 B;  1ZEI A;  1PMX A;  1BQT A;  1GZZ B;  5L3N A;  6INS E;  1TGR A;  3KR3 D;  1GZY B;  2JZQ A;  2LWZ A;  1B9G A;  1H59 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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