1ZEIA

Cross-linked b28 asp insulin
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
53
structure length
53
Chain Sequence
FVNQHLCGSHLVEALYLVCGERGFFYTDKAAKGIVEQCCTSICSLYQLENYCN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
pubmed doi rcsb
molecule tags Hormone
source organism Sus scrofa
molecule keywords INSULIN
total genus 13
structure length 53
sequence length 53
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 1998-07-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00049 Insulin Insulin/IGF/Relaxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.100.10 Mainly Alpha Orthogonal Bundle Insulin-like, subunit E Insulin-like 1zeiA00
2JZQA 2KJIA 5L3NA 1GZYB 1TGRA 1IMXA 1EFEA 1ZEIA 2LWZA 1SJUA 3LRIA 1BQTA 1PMXA 2L29B 1GZZB 3GF1A 5L3MA 4XSSB 1WQJI 2DSRI 5L3LA 2KQPA 2DSPI 1H02B 1H59A 1GZRB 2GF1A 6INSE 1IGLA 1B9GA 2DSQC 3KR3D
chains in the Genus database with same CATH superfamily
2JZQA 2KJIA 5L3NA 1GZYB 1TGRA 1IMXA 1EFEA 1ZEIA 2LWZA 2L14B 1SJUA 3LRIA 1BQTA 1PMXA 2L29B 3F2DA 1GZZB 3GF1A 5L3MA 4XSSB 1WQJI 2DSRI 5L3LA 2KQPA 2DSPI 3F2BA 1H02B 1H59A 1GZRB 3F2CA 2GF1A 6INSE 1IGLA 1B9GA 2DSQC 3KR3D
chains in the Genus database with same CATH topology
2JZQA 2KJIA 5L3NA 1GZYB 1TGRA 1IMXA 1EFEA 1ZEIA 2LWZA 1SJUA 3LRIA 1BQTA 1PMXA 2L29B 1GZZB 3GF1A 5L3MA 4XSSB 1WQJI 2DSRI 5L3LA 2KQPA 2DSPI 1H02B 1H59A 1GZRB 2GF1A 6INSE 1IGLA 1B9GA 2DSQC 3KR3D
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JZQ A;  2KJI A;  5L3N A;  1GZY B;  1TGR A;  1IMX A;  1EFE A;  1ZEI A;  2LWZ A;  1SJU A;  3LRI A;  1BQT A;  1PMX A;  2L29 B;  1GZZ B;  3GF1 A;  5L3M A;  4XSS B;  1WQJ I;  2DSR I;  5L3L A;  2KQP A;  2DSP I;  1H02 B;  1H59 A;  1GZR B;  2GF1 A;  6INS E;  1IGL A;  1B9G A;  2DSQ C;  3KR3 D; 
#chains in the Genus database with same CATH topology
 2JZQ A;  2KJI A;  5L3N A;  1GZY B;  1TGR A;  1IMX A;  1EFE A;  1ZEI A;  2LWZ A;  2L14 B;  1SJU A;  3LRI A;  1BQT A;  1PMX A;  2L29 B;  3F2D A;  1GZZ B;  3GF1 A;  5L3M A;  4XSS B;  1WQJ I;  2DSR I;  5L3L A;  2KQP A;  2DSP I;  3F2B A;  1H02 B;  1H59 A;  1GZR B;  3F2C A;  2GF1 A;  6INS E;  1IGL A;  1B9G A;  2DSQ C;  3KR3 D; 
#chains in the Genus database with same CATH homology
 2JZQ A;  2KJI A;  5L3N A;  1GZY B;  1TGR A;  1IMX A;  1EFE A;  1ZEI A;  2LWZ A;  1SJU A;  3LRI A;  1BQT A;  1PMX A;  2L29 B;  1GZZ B;  3GF1 A;  5L3M A;  4XSS B;  1WQJ I;  2DSR I;  5L3L A;  2KQP A;  2DSP I;  1H02 B;  1H59 A;  1GZR B;  2GF1 A;  6INS E;  1IGL A;  1B9G A;  2DSQ C;  3KR3 D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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