1EFE | Genus

Total Genus 9

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	9
sequence length	60
structure length	60
Chain Sequence	FVNQHLCGSHLVEALYLVCGERGFFYTPKTRRYPGDVKRGIVEQCCTSICSLYQLENYCN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 60 atoms

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60 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hormone/growth factor
source organism	Homo sapiens
publication title	Solution Structure of an Active Mini-Proinsulin, M2PI: Inter-chain Flexibility is Crucial for Insulin Activity pubmed rcsb
molecule keywords	MINI-PROINSULIN
total genus	9
structure length	60
sequence length	60
ec nomenclature
pdb deposition date	2000-02-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00049	Insulin	Insulin/IGF/Relaxin family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.100.10	Mainly Alpha	Orthogonal Bundle	Insulin-like, subunit E	Insulin-like	1efeA00

1IMXA 2DSPI 2DSRI 2KQPA 1PMXA 5L3NA 1BQTA 1ZEIA 1GZYB 1SJUA 2JZQA 6INSE 5L3MA 1EFEA 3KR3D 3GF1A 1GZRB 3LRIA 1IGLA 1TGRA 4XSSB 2L29B 5L3LA 1WQJI 2LWZA 2GF1A 1B9GA 2KJIA 1H02B 1H59A 2DSQC 1GZZB
chains in the Genus database with same CATH superfamily

1IMXA 2DSPI 2DSRI 2KQPA 1PMXA 5L3NA 1BQTA 1ZEIA 1GZYB 1SJUA 2JZQA 6INSE 5L3MA 1EFEA 3KR3D 3GF1A 1GZRB 3F2BA 3LRIA 1IGLA 1TGRA 2L14B 4XSSB 3F2DA 2L29B 5L3LA 1WQJI 2LWZA 2GF1A 1B9GA 2KJIA 1H02B 1H59A 3F2CA 2DSQC 1GZZB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1IMX A;  2DSP I;  2DSR I;  2KQP A;  1PMX A;  5L3N A;  1BQT A;  1ZEI A;  1GZY B;  1SJU A;  2JZQ A;  6INS E;  5L3M A;  1EFE A;  3KR3 D;  3GF1 A;  1GZR B;  3LRI A;  1IGL A;  1TGR A;  4XSS B;  2L29 B;  5L3L A;  1WQJ I;  2LWZ A;  2GF1 A;  1B9G A;  2KJI A;  1H02 B;  1H59 A;  2DSQ C;  1GZZ B; 
#chains in the Genus database with same CATH topology
 1IMX A;  2DSP I;  2DSR I;  2KQP A;  1PMX A;  5L3N A;  1BQT A;  1ZEI A;  1GZY B;  1SJU A;  2JZQ A;  6INS E;  5L3M A;  1EFE A;  3KR3 D;  3GF1 A;  1GZR B;  3F2B A;  3LRI A;  1IGL A;  1TGR A;  2L14 B;  4XSS B;  3F2D A;  2L29 B;  5L3L A;  1WQJ I;  2LWZ A;  2GF1 A;  1B9G A;  2KJI A;  1H02 B;  1H59 A;  3F2C A;  2DSQ C;  1GZZ B; 
#chains in the Genus database with same CATH homology
 1IMX A;  2DSP I;  2DSR I;  2KQP A;  1PMX A;  5L3N A;  1BQT A;  1ZEI A;  1GZY B;  1SJU A;  2JZQ A;  6INS E;  5L3M A;  1EFE A;  3KR3 D;  3GF1 A;  1GZR B;  3LRI A;  1IGL A;  1TGR A;  4XSS B;  2L29 B;  5L3L A;  1WQJ I;  2LWZ A;  2GF1 A;  1B9G A;  2KJI A;  1H02 B;  1H59 A;  2DSQ C;  1GZZ B;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1EFEA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations